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  1. Article ; Online: Am I My Brother's Keeper?

    Lo, Warren D / Torres, Alcy

    Neurology

    2023  Volume 101, Issue 18, Page(s) 773–774

    Language English
    Publishing date 2023-07-25
    Publishing country United States
    Document type Editorial
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000207721
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Infarct Analysis to Explain Outcomes of Perinatal Stroke: Leveling the Mountain Voxel by Voxel.

    Haffner, Darrah / Lo, Warren D

    Neurology

    2023  Volume 101, Issue 15, Page(s) 641–642

    MeSH term(s) Humans ; Stroke/diagnostic imaging ; Brain Ischemia ; Infarction
    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000207776
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Phial of Galadriel.

    Raychev, Radoslav / Lo, Warren D

    Neurology

    2021  Volume 96, Issue 16, Page(s) 729–730

    MeSH term(s) Hospitalization ; Humans ; Long-Term Care ; Patient Discharge ; Stroke
    Language English
    Publishing date 2021-03-23
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000011824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Key Metrics Are Required to Refine Guidelines for Pediatric Mechanical Thrombectomy.

    Beslow, Lauren A / Lo, Warren D

    Stroke

    2021  Volume 52, Issue 4, Page(s) 1222–1224

    MeSH term(s) Benchmarking ; Brain Ischemia ; Child ; Humans ; Thrombectomy
    Language English
    Publishing date 2021-03-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.033561
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: How Plastic Are Children? Does the Age at Stroke Occurrence Matter?

    Beslow, Lauren A / Lo, Warren D

    Neurology

    2021  Volume 98, Issue 7, Page(s) 263–264

    MeSH term(s) Child ; Humans ; Particulate Matter ; Plastics ; Stroke/epidemiology
    Chemical Substances Particulate Matter ; Plastics
    Language English
    Publishing date 2021-12-16
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000013201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Stroke Following Acute Chest Syndrome in a Child With Sickle Cell Disease: A Possible Novel Mechanism.

    Kendel, Nicole E / Lo, Warren D / Villella, Anthony D

    Pediatric neurology

    2021  Volume 125, Page(s) 32–33

    MeSH term(s) Acute Chest Syndrome/complications ; Anemia, Sickle Cell/complications ; Child, Preschool ; Humans ; Male ; Stroke/etiology
    Language English
    Publishing date 2021-09-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 639164-3
    ISSN 1873-5150 ; 0887-8994
    ISSN (online) 1873-5150
    ISSN 0887-8994
    DOI 10.1016/j.pediatrneurol.2021.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Quality of life and paediatric stroke: the shadows of things that may be.

    D Lo, Warren

    Developmental medicine and child neurology

    2017  Volume 59, Issue 1, Page(s) 7–8

    MeSH term(s) Child ; Humans ; Quality of Life ; Stroke
    Language English
    Publishing date 2017
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80369-8
    ISSN 1469-8749 ; 0012-1622
    ISSN (online) 1469-8749
    ISSN 0012-1622
    DOI 10.1111/dmcn.13327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Kidney Transplantation Outcomes From Uncontrolled Donation After Circulatory Death: A Systematic Review and Meta-analysis.

    Vijayan, Keshini / Schroder, Hugh J / Hameed, Ahmer / Hitos, Kerry / Lo, Warren / Laurence, Jerome M / Yoon, Peter D / Nahm, Christopher / Lim, Wai H / Lee, Taina / Yuen, Lawrence / Wong, Germaine / Pleass, Henry

    Transplantation

    2024  

    Abstract: Background: Uncontrolled donation after circulatory death (uDCD) is a potential additional source of donor kidneys. This study reviewed uDCD kidney transplant outcomes to determine if these are comparable to controlled donation after circulatory death ( ... ...

    Abstract Background: Uncontrolled donation after circulatory death (uDCD) is a potential additional source of donor kidneys. This study reviewed uDCD kidney transplant outcomes to determine if these are comparable to controlled donation after circulatory death (cDCD).
    Methods: MEDLINE, Cochrane, and Embase databases were searched. Data on demographic information and transplant outcomes were extracted from included studies. Meta-analyses were performed, and risk ratios (RR) were estimated to compare transplant outcomes from uDCD to cDCD.
    Results: Nine cohort studies were included, from 2178 uDCD kidney transplants. There was a moderate degree of bias, as 4 studies did not account for potential confounding factors. The median incidence of primary nonfunction in uDCD was 12.3% versus 5.7% for cDCD (RR, 1.85; 95% confidence intervals, 1.06-3.23; P = 0.03, I2 = 75). The median rate of delayed graft function was 65.1% for uDCD and 52.0% for cDCD. The median 1-y graft survival for uDCD was 82.7% compared with 87.5% for cDCD (RR, 1.43; 95% confidence intervals, 1.02-2.01; P = 0.04; I2 = 71%). The median 5-y graft survival for uDCD and cDCD was 70% each. Notably, the use of normothermic regional perfusion improved primary nonfunction rates in uDCD grafts.
    Conclusions: Although uDCD outcomes may be inferior in the short-term, the long-term outcomes are comparable to cDCD.
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004937
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: OmicNavigator: open-source software for the exploration, visualization, and archival of omic studies.

    Ernst, Terrence R / Blischak, John D / Nordlund, Paul / Dalen, Joe / Moore, Justin / Bhamidipati, Akshay / Dwivedi, Pankaj / LoGrasso, Joe / Curado, Marco Rocha / Engelmann, Brett Warren

    BMC bioinformatics

    2024  Volume 25, Issue 1, Page(s) 162

    Abstract: Background: The results of high-throughput biology ('omic') experiments provide insight into biological mechanisms but can be challenging to explore, archive and share. The scale of these challenges continues to grow as omic research volume expands and ... ...

    Abstract Background: The results of high-throughput biology ('omic') experiments provide insight into biological mechanisms but can be challenging to explore, archive and share. The scale of these challenges continues to grow as omic research volume expands and multiple analytical technologies, bioinformatic pipelines, and visualization preferences have emerged. Multiple software applications exist that support omic study exploration and/or archival. However, an opportunity remains for open-source software that can archive and present the results of omic analyses with broad accommodation of study-specific analytical approaches and visualizations with useful exploration features.
    Results: We present OmicNavigator, an R package for the archival, visualization and interactive exploration of omic studies. OmicNavigator enables bioinformaticians to create web applications that interactively display their custom visualizations and analysis results linked with app-derived analytical tools, graphics, and tables. Studies created with OmicNavigator can be viewed within an interactive R session or hosted on a server for shared access.
    Conclusions: OmicNavigator can be found at https://github.com/abbvie-external/OmicNavigator.
    MeSH term(s) Software ; Computational Biology/methods ; User-Computer Interface ; Computer Graphics
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2041484-5
    ISSN 1471-2105 ; 1471-2105
    ISSN (online) 1471-2105
    ISSN 1471-2105
    DOI 10.1186/s12859-024-05743-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Arterial Ischemic Stroke in Children and Young Adults.

    Lo, Warren D / Kumar, Riten

    Continuum (Minneapolis, Minn.)

    2017  Volume 23, Issue 1, Cerebrovascular Disease, Page(s) 158–180

    Abstract: Purpose of review: This article reviews risk factors, recurrence risk, evaluation, management, and outcomes of arterial ischemic stroke in children and young adults.: Recent findings: The risk for recurrence and mortality appear to be low for ... ...

    Abstract Purpose of review: This article reviews risk factors, recurrence risk, evaluation, management, and outcomes of arterial ischemic stroke in children and young adults.
    Recent findings: The risk for recurrence and mortality appear to be low for neonatal and childhood stroke. Most children have relatively mild deficits, but those who have greater neurologic deficits, poststroke epilepsy, or strokes early in life are at risk for lower overall cognitive function. Stroke recurrence and long-term mortality after stroke in young adults are greater than originally thought. Cognitive impairments, depression, and anxiety are associated with higher levels of poststroke unemployment and represent targets for improved poststroke care. Poststroke care in young adults involves more than medical management. Self-reported memory and executive function impairments may be more severe than what is detected by objective measures. Assessment of possible cognitive impairments and appropriate management of psychological comorbidities are key to maximizing the long-term functional outcome of stroke survivors.
    Summary: Childhood and young adult stroke survivors survive for many more years than older patients with stroke. To ensure that these survivors maximize the productivity of their lives, neurologists must not only optimize medical management but also recognize that impairments in cognition and mood may be remediable barriers to long-term functional independence.
    MeSH term(s) Child ; Cognition ; Cognition Disorders/complications ; Cognition Disorders/diagnosis ; Cognition Disorders/etiology ; Depression/diagnosis ; Depression/physiopathology ; Executive Function/physiology ; Female ; Humans ; Stroke/diagnosis ; Stroke/etiology ; Stroke/therapy ; Young Adult
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, N.I.H., Extramural ; Review
    ISSN 1538-6899
    ISSN (online) 1538-6899
    DOI 10.1212/CON.0000000000000438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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