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  1. Article ; Online: Perspectives on Low-grade Sarcomas: The Extraordinary Contributions of Sharon W. Weiss, MD.

    Hastings, Hope / Goldblum, John R

    Advances in anatomic pathology

    2017  Volume 24, Issue 4, Page(s) 195–200

    Abstract: Soft-tissue pathology encompasses a wide spectrum of neoplasms that represent some of the most challenging and problematic tumors in surgical pathology. Owing to the intensive work of dedicated pathologists, this once esoteric field has become ... ...

    Abstract Soft-tissue pathology encompasses a wide spectrum of neoplasms that represent some of the most challenging and problematic tumors in surgical pathology. Owing to the intensive work of dedicated pathologists, this once esoteric field has become increasingly well defined. In this review, Dr Sharon Weiss' monumental contributions to low-grade sarcomas, including low-grade fibromyxoid sarcoma/so-called hyalinizing spindle cell tumor, atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma, epithelioid hemangioendothelioma, and dermatofibrosarcoma protuberans with fibrosarcomatous transformation will be discussed.
    Language English
    Publishing date 2017-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1212493-x
    ISSN 1533-4031 ; 1072-4109
    ISSN (online) 1533-4031
    ISSN 1072-4109
    DOI 10.1097/PAP.0000000000000145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4118: Show issues Location:
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  2. Article ; Online: Advances in Hernia Care State of the Art.

    Hope, William W

    The American surgeon

    2024  , Page(s) 31348241241717

    Abstract: The field of hernia surgery has seen many recent advances and continues to evolve. Care of the hernia patient begins preoperatively by ensuring adequate preparation for surgery with surgeons now having the opportunity to accurately predict risk which can ...

    Abstract The field of hernia surgery has seen many recent advances and continues to evolve. Care of the hernia patient begins preoperatively by ensuring adequate preparation for surgery with surgeons now having the opportunity to accurately predict risk which can aid with informed consent. Imaging studies can now help surgeons diagnose and plan hernia surgery on an individual level based on hernia characteristics as well as abdominal wall musculature. In the operating room, new technology and surgical techniques have allowed surgeons to become increasingly sophisticated with goals of reducing tension on midline closures, utilizing minimally invasive and robotic techniques, and availability of new and varied mesh prosthetics. While modest improvements in outcomes have been witnessed by these advances, there is still opportunity for improvement which will be realized by continued research, use of registries, and education and training. Hernia prevention strategies focusing on minimally invasive surgery, laparotomy closure, and the use of prophylactic mesh will also help with the burden of incisional hernias. These advances in hernia surgery have led to the new field of Abdominal Core Health which helps represent this evolving and growing new subspecialty of general surgery.
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348241241717
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: / by D. W. Dellinger

    Dellinger, D. W / Hope, E. R / Katsura, Makio / Nishida, Tatsuo

    Papers in South-East Asian linguistics

    (Pacific linguistics : Series A ; No. 30 ; Papers in South East Asian linguistics ; No. 3)

    1973  

    Series title Pacific linguistics : Series A ; No. 30
    Papers in South East Asian linguistics ; No. 3
    Language English
    Size iv, 82 S
    Publisher Univ
    Publishing place Canberra
    Document type Book
    ZDB-ID 802043-7
    ISBN 0858830914 ; 9780858830912
    ISSN 0078-9178
    Database Former special subject collection: coastal and deep sea fishing

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  4. Article: [Rezension von: Pomfret, Richard W. T., Constructing a market economy, diverse paths from central planning in Asia and Europe]

    Hope, Nicholas C / Pomfret, Richard

    Journal of economic literature Vol. 41, No. 4 , p. 1328-1329

    2003  Volume 41, Issue 4, Page(s) 1328–1329

    Language English
    Publisher Assoc
    Publishing place Nashville, Tenn
    Document type Article
    ZDB-ID 3076-4 ; 2010159-4
    ISSN 0022-0515
    ISSN 0022-0515
    Database ECONomics Information System

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  5. Article ; Online: Development and application of neonatal physiology-based pharmacokinetic models of amikacin and fosfomycin to assess pharmacodynamic target attainment.

    Darlow, Christopher A / Parrott, Neil / Peck, Richard W / Hope, William

    CPT: pharmacometrics & systems pharmacology

    2024  Volume 13, Issue 3, Page(s) 464–475

    Abstract: Antimicrobial resistance increasingly complicates neonatal sepsis in a global context. Fosfomycin and amikacin are two agents being tested in an ongoing multicenter neonatal sepsis trial. Although neonatal pharmacokinetics (PKs) have been described for ... ...

    Abstract Antimicrobial resistance increasingly complicates neonatal sepsis in a global context. Fosfomycin and amikacin are two agents being tested in an ongoing multicenter neonatal sepsis trial. Although neonatal pharmacokinetics (PKs) have been described for these drugs, the physiological variability within neonatal populations makes population PKs in this group uncertain. Physiologically-based pharmacokinetic (PBPK) models were developed in Simcyp for fosfomycin and amikacin sequentially for adult, pediatric, and neonatal populations, with visual and quantitative validation compared to observed data at each stage. Simulations were performed using the final validated neonatal models to determine drug exposures for each drug across a demographic range, with probability of target attainment (PTA) assessments. Successfully validated neonatal PBPK models were developed for both fosfomycin and amikacin. PTA analysis demonstrated high probability of target attainment for amikacin 15 mg/kg i.v. q24h and fosfomycin 100 mg/kg (in neonates aged 0-7 days) or 150 mg/kg (in neonates aged 7-28 days) i.v. q12h for Enterobacterales with fosfomycin and amikacin minimum inhibitory concentrations at the adult breakpoints. Repeat analysis in premature populations demonstrated the same result. PTA analysis for a proposed combination fosfomycin-amikacin target was also performed. The simulated regimens, tested in a neonatal sepsis trial, are likely to be adequate for neonates across different postnatal ages and gestational age. This work demonstrates a template for determining target attainment for antimicrobials (alone or in combination) in special populations without sufficient available PK data to otherwise assess with traditional pharmacometric methods.
    MeSH term(s) Humans ; Infant, Newborn ; Amikacin/pharmacokinetics ; Anti-Bacterial Agents/pharmacokinetics ; Fosfomycin/pharmacokinetics ; Microbial Sensitivity Tests ; Neonatal Sepsis/drug therapy ; Multicenter Studies as Topic ; Clinical Trials as Topic
    Chemical Substances Amikacin (84319SGC3C) ; Anti-Bacterial Agents ; Fosfomycin (2N81MY12TE)
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2697010-7
    ISSN 2163-8306 ; 2163-8306
    ISSN (online) 2163-8306
    ISSN 2163-8306
    DOI 10.1002/psp4.13097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: / by Warren W. Glover, Maria Hari, E. R. Hope

    Glover, Warren W / Hari, Maria / Hope, E. R

    Papers in South-East Asian linguistics

    (Pacific linguistics : Series A, Occasional papers ; No. 29 ; Papers in South East Asian linguistics ; No. 2)

    1971  

    Series title Pacific linguistics : Series A, Occasional papers ; No. 29
    Papers in South East Asian linguistics ; No. 2
    Language English
    Size iv, 78 S, graph. Darst., 1 Kt
    Publisher Univ
    Publishing place Canberra
    Document type Book
    ZDB-ID 802043-7
    ISBN 0858830310 ; 9780858830318
    ISSN 0078-9178
    Database Former special subject collection: coastal and deep sea fishing

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  7. Article: A Simplified Abdominal Wall Model to Teach Complex Abdominal Wall Reconstruction.

    Bilezikian, Jordan A / Hope, William W

    Plastic and reconstructive surgery. Global open

    2022  Volume 10, Issue 5, Page(s) e4322

    Abstract: A simplified and functional abdominal wall model is necessary for surgical education. The utility of such a model encompasses medical student, resident, and fellow education. This is especially relevant in the fields of general surgery and plastic ... ...

    Abstract A simplified and functional abdominal wall model is necessary for surgical education. The utility of such a model encompasses medical student, resident, and fellow education. This is especially relevant in the fields of general surgery and plastic surgery. An abdominal wall model helps with a more complete understanding of abdomen access, hernia repair, and complex abdominal wall reconstruction. Although several models have been proposed, they are expensive and limitations exist due to access, costly repairs, maintenance, and part replacements. There is currently no consensus or widely adopted model used in surgical training programs. We present a simplified abdominal wall model that is inexpensive and easily reproducible.
    Language English
    Publishing date 2022-05-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000004322
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7091: Show issues Location:
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  8. Article ; Online: Modelled impact of Tiny Targets on the distribution and abundance of riverine tsetse.

    Vale, Glyn A / Hargrove, John W / Hope, Andrew / Torr, Steve J

    PLoS neglected tropical diseases

    2024  Volume 18, Issue 4, Page(s) e0011578

    Abstract: Background: The insecticide-treated baits known as Tiny Targets are one of the cheapest means of controlling riverine species of tsetse flies, the vectors of the trypanosomes that cause sleeping sickness in humans. Models of the efficacy of these ... ...

    Abstract Background: The insecticide-treated baits known as Tiny Targets are one of the cheapest means of controlling riverine species of tsetse flies, the vectors of the trypanosomes that cause sleeping sickness in humans. Models of the efficacy of these targets deployed near rivers are potentially useful in planning control campaigns and highlighting the principles involved.
    Methods and principal findings: To evaluate the potential of models, we produced a simple non-seasonal model of the births, deaths, mobility and aging of tsetse, and we programmed it to simulate the impact of seven years of target use against the tsetse, Glossina fuscipes fuscipes, in the riverine habitats of NW Uganda. Particular attention was given to demonstrating that the model could explain three matters of interest: (i) good control can be achieved despite the degradation of targets, (ii) local elimination of tsetse is impossible if invasion sources are not tackled, and (iii) with invasion and target degradation it is difficult to detect any effect of control on the age structure of the tsetse population.
    Conclusions: Despite its simplifications, the model can assist planning and teaching, but allowance should be made for any complications due to seasonality and management challenges associated with greater scale.
    MeSH term(s) Tsetse Flies/physiology ; Tsetse Flies/parasitology ; Animals ; Insect Control/methods ; Uganda ; Insecticides/pharmacology ; Humans ; Trypanosomiasis, African/prevention & control ; Trypanosomiasis, African/epidemiology ; Insect Vectors/parasitology ; Insect Vectors/physiology
    Chemical Substances Insecticides
    Language English
    Publishing date 2024-04-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0011578
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Correlates of Spirituality among African American and Black Caribbean Emerging Adults.

    Hope, Meredith O / Nguyen, Ann W / Taylor, Robert Joseph / Chatters, Linda

    Religions

    2024  Volume 15, Issue 3

    Abstract: Spirituality is a significant cultural strength and resource for Black emerging adults. Numerous studies show that increasing numbers of emerging adults tend to identify themselves as being spiritual but not religious. However, no studies to date have ... ...

    Abstract Spirituality is a significant cultural strength and resource for Black emerging adults. Numerous studies show that increasing numbers of emerging adults tend to identify themselves as being spiritual but not religious. However, no studies to date have identified the demographic correlates of spirituality for Black emerging adults from different ethnic groups (i.e., African American vs. Black Caribbean). Data from the National Survey of American Life was used to identify the demographic correlates of 2 indicators of spirituality (e.g., self-rated spirituality and subjective spirituality) for 802 African American and 428 Black Caribbean emerging adults using linear regression. For African Americans, being a woman predicted both greater self-rated spirituality and subjective spirituality. However, among Black Caribbeans men rated spirituality higher in importance than women. African Americans who reported higher educational attainment tended to report higher levels of self-rated spirituality and subjective spirituality. Romantic status for Black Caribbeans, whether they had no romantic involvement or a current romantic partner, was associated with lower self-ratings of spirituality. Unmarried cohabitating individuals in both ethnic groups tended to report lower levels of self-related spirituality. Unemployment for Black Caribbeans was associated with lower subjective spirituality. Findings are of interest to those who serve and work with Black emerging adults.
    Language English
    Publishing date 2024-03-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620962-7
    ISSN 2077-1444
    ISSN 2077-1444
    DOI 10.3390/rel15030341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Invited comment to: European Hernia Society Guidelines on prevention and treatment of parastomal hernias.

    Hope, W W

    Hernia : the journal of hernias and abdominal wall surgery

    2017  Volume 22, Issue 1, Page(s) 201

    MeSH term(s) Hernia, Ventral ; Humans
    Language English
    Publishing date 2017-11-14
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1388125-5
    ISSN 1248-9204 ; 1265-4906
    ISSN (online) 1248-9204
    ISSN 1265-4906
    DOI 10.1007/s10029-017-1694-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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