LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 8153

Search options

  1. Article ; Online: Gordon M. Cragg, D.Phil., D.Sc. (h.c.): a man for all natural products.

    Bolzani, Vanderlan da Silva / Davies-Coleman, Michael / Newman, David J / Singh, Sheo B

    Journal of natural products

    2012  Volume 75, Issue 3, Page(s) 309–310

    MeSH term(s) Biological Products ; Humans ; Male
    Chemical Substances Biological Products
    Language English
    Publishing date 2012-03-23
    Publishing country United States
    Document type Editorial ; Portraits
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/np201003c
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Metabolism of Tritiated Gibberellins in d-5 Dward Maize: II. [H]Gibberellin A(1), [H]Gibberellin A(3), and Related Compounds.

    Davies, L J / Rappaport, L

    Plant physiology

    2006  Volume 56, Issue 1, Page(s) 60–66

    Abstract: After 30 minutes of incubation of young leaf sections of d-5 maize (Zea mays L.) in [(3)H ... 3)H]GA(1) and [(3)H]GA(3), with their identical D ring structures, were converted to [(3)H]GA(1)-X ... type compounds; [(3)H]-ketoGA(1) and [(3)H]tetrahydroGA(3), with modified D rings, were not converted ...

    Abstract After 30 minutes of incubation of young leaf sections of d-5 maize (Zea mays L.) in [(3)H]gibberellin A(1) ([(3)H]GA(1)), the metabolite [(3)H]GA(8) was present in significant amounts, with a second metabolite, [(3)H]GA(8)-glucose ([(3)H]GA(8)-glu), appearing soon after. A third [(3)H]GA(1) metabolite, the polar uncharacterized conjugate [(3)H]GA(1)-X, took more than 1 hour to appear. The protein synthesis inhibitor cycloheximide inhibited the production of all [(3)H]GA(1) metabolites, indicating a possible protein synthesis requirement for [(3)H]GA(1) metabolism.By preincubating leaf sections in unlabeled GA(1) before exposure to [(3)H]GA(1) or by reducing the specific radioactivity of the [(3)H]GA(1) supplied, it was possible to reduce greatly the conversion of radioactive GA(1) to [(3)H]GA(8)-glu, without affecting conversion to [(3)H]GA(1)-X. Increasing the molar concentration of the [(3)H]GA(1) fed greatly increased the molar yield of [(3)H]GA(1)-X, whereas the molar yields of [(3)H]GA(8) and [(3)H]GA(8)-glu were much less affected.The principal metabolite of [(3)H]GA(3) was a very polar compound having chromatographic properties similar to those of the conjugate [(3)H]GA(1)-X produced from [(3)H]GA(1). The naturally occurring GAs [(3)H]GA(1), [(3)H]GA(3), and [(3)H]tetrahydroGA(3) were metabolized to a much greater extent than were the artifical derivatives [(3)H]ketoGA(1), [(3)H]GA(1)-methyl ester, and [(3)H]pseudoGA(1). Only [(3)H]GA(1) and [(3)H]GA(3), with their identical D ring structures, were converted to [(3)H]GA(1)-X type compounds; [(3)H]-ketoGA(1) and [(3)H]tetrahydroGA(3), with modified D rings, were not converted to this type of conjugate.
    Language English
    Publishing date 2006-04-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208914-2
    ISSN 1532-2548 ; 0032-0889
    ISSN (online) 1532-2548
    ISSN 0032-0889
    DOI 10.1104/pp.56.1.60
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Isolation and characterization of diastereomers of discorhabdins H and K and assignment of absolute configuration to discorhabdins D, N, Q, S, T, and U.

    Grkovic, Tanja / Pearce, A Norrie / Munro, Murray H G / Blunt, John W / Davies-Coleman, Michael T / Copp, Brent R

    Journal of natural products

    2010  Volume 73, Issue 10, Page(s) 1686–1693

    Abstract: ... assigned to the known metabolites discorhabdins H, D, 2-hydroxy-D, N, and Q by comparison of ECD spectra ... waters has led to the characterization of a new diastereomer of discorhabdin H, named discorhabdin H2 ...

    Abstract Investigations of four different sponge populations of Latrunculia species collected in New Zealand waters has led to the characterization of a new diastereomer of discorhabdin H, named discorhabdin H2, confirmation of the structure of discorhabdin K ((+)-7), and presentation of a new diastereomer, discorhabdin K2 ((-)-8). In each case the structures were established by extensive NMR and MS studies and the absolute configurations interrogated by electronic circular dichroism (ECD). Absolute configurations were assigned to the known metabolites discorhabdins H, D, 2-hydroxy-D, N, and Q by comparison of ECD spectra with those recorded for discorhabdin alkaloids of defined absolute configuration, while the configurations of discorhabdins S, T, and U were assigned by semisynthesis from (+)-(6S,8S)-discorhabdin B.
    MeSH term(s) Alkaloids/chemistry ; Animals ; Molecular Structure ; New Zealand ; Porifera/chemistry ; Pyrroles/chemistry ; Pyrroles/isolation & purification ; Quinolones ; Quinones/chemistry ; Quinones/isolation & purification ; Spiro Compounds/chemistry ; Spiro Compounds/isolation & purification ; Stereoisomerism ; Thiazepines
    Chemical Substances Alkaloids ; Pyrroles ; Quinolones ; Quinones ; Spiro Compounds ; Thiazepines ; discorhabdin B ; discorhabdin H ; discorhabdin K ; discorhabdin S
    Language English
    Publishing date 2010-10-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/np100443c
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Al-H and Al-D complexes in Si: A uniaxial-stress study of the hydrogen vibrational modes.

    Stavola / Cheng / Davies

    Physical review. B, Condensed matter

    1996  Volume 54, Issue 16, Page(s) 11322–11330

    Language English
    Publishing date 1996-10-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209770-9
    ISSN 1095-3795 ; 1550-235X ; 0163-1829 ; 2469-9950 ; 1098-0121 ; 0556-2805
    ISSN (online) 1095-3795 ; 1550-235X
    ISSN 0163-1829 ; 2469-9950 ; 1098-0121 ; 0556-2805
    DOI 10.1103/physrevb.54.11322
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Occupational health and the 1975 d.i.h. course.

    Davies, J B

    Proceedings of the Mine Medical Officers' Association of S. A

    1976  Volume 56, Issue 422, Page(s) 16–19

    MeSH term(s) Curriculum ; Education, Medical, Graduate ; Occupational Medicine/education
    Language English
    Publishing date 1976-01
    Publishing country South Africa
    Document type Journal Article
    ZDB-ID 603999-6
    ISSN 0026-4490
    ISSN 0026-4490
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: The First Crystallographic Evidence for the Structures of ortho-Lithiated Aromatic Tertiary Amides This work was supported by the UK EPSRC (M.A.H.), and St. Catharine's (R.P.D.) and Gonville & Caius (A.E.H.W.) Colleges, Cambridge.

    Clayden, Jonathan / Davies, Robert P. / Hendy, Mark A. / Snaith, Ronald / Wheatley, Andrew E. H.

    Angewandte Chemie (International ed. in English)

    2001  Volume 40, Issue 7, Page(s) 1238–1240

    Language English
    Publishing date 2001-04-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Effect of Mercury in Acute Rheumatism.

    Davies, D H

    The Medical and physical journal

    2018  Volume 26, Issue 152, Page(s) 277–278

    Language English
    Publishing date 2018-11-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2535269-6
    ISSN 0267-0100
    ISSN 0267-0100
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: On Calomel and Opium in Rheumatism.

    Davies, D H

    The Medical and physical journal

    2018  Volume 26, Issue 151, Page(s) 210–212

    Language English
    Publishing date 2018-11-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2535269-6
    ISSN 0267-0100
    ISSN 0267-0100
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Mr. Davies's Case of Poison by Arsenic.

    Davies, D H

    The Medical and physical journal

    2018  Volume 28, Issue 165, Page(s) 345–350

    Language English
    Publishing date 2018-11-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2535269-6
    ISSN 0267-0100
    ISSN 0267-0100
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Case of Tumor on the Nose, by Mr. Davies.

    Davies, D H

    The Medical and physical journal

    2018  Volume 29, Issue 171, Page(s) 391–393

    Language English
    Publishing date 2018-11-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2535269-6
    ISSN 0267-0100
    ISSN 0267-0100
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top