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  1. Article ; Online: Fungal Secondary Metabolites/Dicationic Pyridinium Iodide Combinations in Combat against Multi-Drug Resistant Microorganisms.

    Abdelalatif, Ayoub M / Elwakil, Bassma H / Mohamed, Mohamed Zakaria / Hagar, Mohamed / Olama, Zakia A

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 6

    Abstract: The spread of antibiotic-resistant opportunistic microbes is a huge socioeconomic burden and a growing concern for global public health. In the current study, two endophytic fungal strains were isolated ... ...

    Abstract The spread of antibiotic-resistant opportunistic microbes is a huge socioeconomic burden and a growing concern for global public health. In the current study, two endophytic fungal strains were isolated from
    MeSH term(s) Iodides/metabolism ; Escherichia coli ; Oleic Acid/metabolism ; Aspergillus niger/metabolism ; Complex Mixtures/metabolism
    Chemical Substances Iodides ; Oleic Acid (2UMI9U37CP) ; Complex Mixtures
    Language English
    Publishing date 2023-03-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28062434
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    Zs.MO 81: Show issues

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  2. Article ; Online: Case study of chemical and enzymatic degumming processes in soybean oil production at an industrial plant.

    Khamies, Maged / Hagar, Mohamed / Kassem, Taher S E / Moustafa, Amira Hossam Eldin

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4064

    Abstract: The vegetable oil degumming process plays a critical role in refining edible oil. Phospholipids (PL) removal from crude extracted soybean oil (SBO) by the enzymatic degumming process has been investigated in this work. Enzymatic degumming of extracted ... ...

    Abstract The vegetable oil degumming process plays a critical role in refining edible oil. Phospholipids (PL) removal from crude extracted soybean oil (SBO) by the enzymatic degumming process has been investigated in this work. Enzymatic degumming of extracted SBO with microbial phospholipase A1 PLA-1 Quara LowP and Lecitase Ultra enzymes have also been studied comparatively. The main novelty of our work is the use of the enzymatic degumming process on an industrial scale (600 tons a day). Many parameters have been discussed to understand in detail the factors affecting oil losses during the degumming process. The factors such as chemical conditioning (CC) by phosphoric acid 85%, the enzyme dosage mg/kg (feedstock dependent), the enzymatic degumming reaction time, and the characteristics of the plant-processed SBO have been discussed in detail. As a main point, the degummed oil with a phosphorus content of < 10 mg/kg increases yield. Quara LowP and Lecitase Ultra enzymes are not specific for certain phospholipids PL; however, the conversion rate depends on the SBO phospholipid composition. After 4 h, over 99% of Phospholipids were degraded to their lysophospholipid LPL (lysolecithin). The results showed a significant effect of operating parameters and characteristics of different origins of SBO, fatty acids FFA content, Phosphorus content and total divalent metals (Calcium Ca, Magnesium Mg and Iron Fe mg/kg) content on the oil loss. The benefit of using enzymatic degumming of vegetable oils rather than traditional chemical refining is that the enzymatic degumming process reduces total oil loss. This decrease is known as enzymatic yield. The enzymatic degumming also decreases wastewater and used chemicals and running costs; moreover, it enables physical refining by lowering the residue phosphorus to < 10 mg/kg.
    MeSH term(s) Soybean Oil/chemistry ; Plant Oils/chemistry ; Phospholipids ; Phospholipases A1 ; Manufacturing and Industrial Facilities ; Phosphorus
    Chemical Substances Soybean Oil (8001-22-7) ; Plant Oils ; Phospholipids ; Phospholipases A1 (EC 3.1.1.32) ; Phosphorus (27YLU75U4W)
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-53865-9
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  3. Article ; Online: Corrigendum to "Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway" [Food and Chemical Toxicology 184 (2024) 114386].

    Shendy, Hagar M / Mohamed, Sarah S / Abd El-Haleim, Enas A / Galal, Omneya / Wadie, Walaa / Helal, Amr / Khayyal, Mohamed T

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2024  Volume 188, Page(s) 114639

    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Published Erratum
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2024.114639
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    Zs.A 529: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: Fungal Secondary Metabolites/Dicationic Pyridinium Iodide Combinations in Combat against Multi-Drug Resistant Microorganisms

    Ayoub M. Abdelalatif / Bassma H. Elwakil / Mohamed Zakaria Mohamed / Mohamed Hagar / Zakia A. Olama

    Molecules, Vol 28, Iss 2434, p

    2023  Volume 2434

    Abstract: The spread of antibiotic-resistant opportunistic microbes is a huge socioeconomic burden and a growing concern for global public health. In the current study, two endophytic fungal strains were isolated from Mangifera Indica roots and identified as ... ...

    Abstract The spread of antibiotic-resistant opportunistic microbes is a huge socioeconomic burden and a growing concern for global public health. In the current study, two endophytic fungal strains were isolated from Mangifera Indica roots and identified as Aspergillus niger MT597434.1 and Trichoderma lixii KU324798.1. Secondary metabolites produced by A. niger and T. lixii were extracted and tested for their antimicrobial activity. The highest activity was noticed against Staphylococcus aureus and E. coli treated with A. niger and T. lixii secondary metabolites, respectively. A. niger crude extract was mainly composed of Pentadecanoic acid, 14-methyl-, methyl ester and 9-Octadecenoic acid ( Z )-, methyl ester (26.66 and 18.01%, respectively), while T. lixii crude extract’s major components were 2,4-Decadienal, ( E , E ) and 9-Octadecenoic acid ( Z )-, and methyl ester (10.69 and 10.32%, respectively). Moreover, a comparative study between the fungal extracts and dicationic pyridinium iodide showed that the combination of A. niger and T. lixii secondary metabolites with dicationic pyridinium iodide compound showed a synergistic effect against Klebsiella pneumoniae . The combined formulae inhibited the bacterial growth after 4 to 6 h through cell wall breakage and cells deformation, with intracellular components leakage and increased ROS production.
    Keywords endophytic fungi ; Trichoderma lixii ; Aspergillus niger ; dicationic pyridinium iodide ; multi-drug resistant ; Organic chemistry ; QD241-441
    Subject code 500
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Sulfadiazine analogs: anti-Toxoplasma in vitro study of sulfonamide triazoles.

    Arafa, Fadwa M / Osman, Doaa Hassan / Tolba, Mona Mohamed / Rezki, Nadjet / Aouad, Mohamed R / Hagar, Mohamed / Osman, Mervat / Said, Heba

    Parasitology research

    2023  Volume 122, Issue 10, Page(s) 2353–2365

    Abstract: Toxoplasmosis is an infection that prevails all over the world and is caused by the obligate intracellular protozoan parasite Toxoplasma gondii (T. gondii). Promising novel compounds for the treatment of T. gondii are introduced in the current ... ...

    Abstract Toxoplasmosis is an infection that prevails all over the world and is caused by the obligate intracellular protozoan parasite Toxoplasma gondii (T. gondii). Promising novel compounds for the treatment of T. gondii are introduced in the current investigation. In order to test their in vitro potency against T. gondii tachyzoites, six 1,2,3-triazoles-based sulfonamide scaffolds with terminal NH
    MeSH term(s) Sulfadiazine/pharmacology ; Toxoplasma ; Sulfanilamide ; Sulfonamides ; Triazoles
    Chemical Substances Sulfadiazine (0N7609K889) ; Sulfanilamide (21240MF57M) ; Sulfonamides ; Triazoles
    Language English
    Publishing date 2023-08-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 284966-5
    ISSN 1432-1955 ; 0932-0113 ; 0044-3255
    ISSN (online) 1432-1955
    ISSN 0932-0113 ; 0044-3255
    DOI 10.1007/s00436-023-07936-x
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    Uh II Zs.124: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Lattice-charge imbalance and redox catalysis over perovskite-type ferrite- and manganite-based mixed oxides as studied by XRD, FTIR, UV-Vis DRS, and XPS.

    Mekhemer, Gamal A H / Mohamed, Hagar A A / Bumajdad, Ali / Zaki, Mohamed I

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 7453

    Abstract: In the present investigation, two sets of pure and substituted ferrite- and manganite-based mixed oxides were prepared within the stoichiometric formula[Formula: see text], where A = Bi or La, ... ...

    Abstract In the present investigation, two sets of pure and substituted ferrite- and manganite-based mixed oxides were prepared within the stoichiometric formula[Formula: see text], where A = Bi or La, A
    Language English
    Publishing date 2023-05-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-34065-3
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  7. Article ; Online: Novel Novolac Phenolic Polymeric Network of Chalcones: Synthesis, Characterization, and Thermal-Electrical Conductivity Investigation.

    Sharshira, Essam Mohamed / Ataalla, Ahmed A / Hagar, Mohamed / Salah, Mohammed / Jaremko, Mariusz / Shehata, Nader

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 17

    Abstract: A series of novolac phenolic polymeric networks (NPPN) were prepared via an acid-catalyzed polycondensation reaction of formaldehyde with chalcones possessing ... ...

    Abstract A series of novolac phenolic polymeric networks (NPPN) were prepared via an acid-catalyzed polycondensation reaction of formaldehyde with chalcones possessing a
    MeSH term(s) Chalcone ; Chalcones ; Electric Conductivity ; Formaldehyde ; Phenols ; Polymers
    Chemical Substances Chalcones ; Phenols ; Polymers ; Formaldehyde (1HG84L3525) ; Chalcone (5S5A2Q39HX)
    Language English
    Publishing date 2022-08-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27175409
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    Zs.MO 81: Show issues

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  8. Article ; Online: Anticorrosive performance of newly synthesized dipyridine based ionic liquids by experimental and theoretical approaches.

    Moustafa, Amira Hossam Eldin / Abdel-Rahman, Hanaa H / Hagar, Mohamed / Aouad, Mohamed R / Rezki, Nadjet / Bishr, Sherif A A

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 19197

    Abstract: Two newly synthetic nontoxic dipyridine-based ionic liquids ( ... ...

    Abstract Two newly synthetic nontoxic dipyridine-based ionic liquids (P
    Language English
    Publishing date 2023-11-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-45822-9
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  9. Article ; Online: Lattice-charge imbalance and redox catalysis over perovskite-type ferrite- and manganite-based mixed oxides as studied by XRD, FTIR, UV–Vis DRS, and XPS

    Gamal A. H. Mekhemer / Hagar A. A. Mohamed / Ali Bumajdad / Mohamed I. Zaki

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 9

    Abstract: Abstract In the present investigation, two sets of pure and substituted ferrite- and manganite-based mixed oxides were prepared within the stoichiometric formula $$A_{1 - x} A^{\prime}_{x} B_{1 - x} B^{\prime}_{x} O_{3}$$ A 1 - x A x ′ B 1 - x B x ′ O 3 , ...

    Abstract Abstract In the present investigation, two sets of pure and substituted ferrite- and manganite-based mixed oxides were prepared within the stoichiometric formula $$A_{1 - x} A^{\prime}_{x} B_{1 - x} B^{\prime}_{x} O_{3}$$ A 1 - x A x ′ B 1 - x B x ′ O 3 , where A = Bi or La, A ′ = Sr, B = Fe or Mn, B′ = Co, x = 0 or 0.2, by calcination at 700 °C (for 1 h) of corresponding metal citrate xerogels. Materials thus obtained were examined for bulk and surface characteristics using X-ray diffractometry, ex situ Fourier transform infrared spectroscopy, UV–Vis diffuse reflectance spectroscopy, X-ray photoelectron spectroscopy, and N2 sorptiometry. Their redox catalytic activity was evaluated towards a 2-propanol dehydrogenation reaction in the gas phase by employing in situ Fourier transform infrared spectroscopy. The results obtained could help reveal that (1) the presence of Bi (versus La) and Mn (versus Fe) facilitated the formation of polymeric crystalline phases assuming lattice-charge imbalance (due to excess positive charge), (2) the surface exposure of the excess positive charge was manifested in the generation of Mn sites having various oxidation states ≥ 3+, (3) the consequent development of visible light absorptions at 498–555 nm suggested occurrence of electron double-exchange facilitated by the formation of Mnn+–O2−–Mn(n+1)+ Zener-type linkages, and (4) the exposure of such linkages at the surface warrants the establishment of the electron-mobile environment necessitated by the redox catalytic activity. Moreover, the relationship between the alcohol dehydrogenation activity and the magnitude of the lattice-charge imbalance (i.e., the net excess positive charge) of the catalysts was highlighted.
    Keywords Medicine ; R ; Science ; Q
    Subject code 540
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Nanoformulation-Based 1,2,3-Triazole Sulfonamides for Anti-

    Arafa, Fadwa M / Said, Heba / Osman, Doaa / Rezki, Nadjet / Aouad, Mohamed R / Hagar, Mohamed / Osman, Mervat / Elwakil, Bassma H / Jaremko, Mariusz / Tolba, Mona Mohamed

    Tropical medicine and infectious disease

    2023  Volume 8, Issue 8

    Abstract: Toxoplasma ... ...

    Abstract Toxoplasma gondii
    Language English
    Publishing date 2023-08-07
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed8080401
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