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  1. Article: Detection of moisture ratio and carotenoid compounds in mamey (

    López-Morales, Guadalupe / López-Páez, Maria Fernanda / López, Pascual / Carriles, Ramón / Vilchis, Heber

    Journal of food science and technology

    2023  Volume 60, Issue 7, Page(s) 1952–1959

    Abstract: This work presents the study of the moisture ratio and carotenoid compounds in dried mamey ( ...

    Abstract This work presents the study of the moisture ratio and carotenoid compounds in dried mamey (
    Language English
    Publishing date 2023-03-23
    Publishing country India
    Document type Journal Article
    ZDB-ID 242498-8
    ISSN 0975-8402 ; 0022-1155
    ISSN (online) 0975-8402
    ISSN 0022-1155
    DOI 10.1007/s13197-023-05728-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Terahertz time-domain imaging for the examination of gilded wooden artifacts.

    Reyes-Reyes, Edgar Santiago / Carriles-Jaimes, Ramón / D'Angelo, Emanuele / Nazir, Saad / Koch-Dandolo, Corinna Ludovica / Kuester, Falko / Jepsen, Peter Uhd / Castro-Camus, Enrique

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6261

    Abstract: Terahertz imaging is unlocking unique capabilities for the analysis of cultural heritage artifacts. This paper uses terahertz time-domain imaging for the study of a gilded wooden artifact, providing a means to perform stratigraphic analysis, yielding ... ...

    Abstract Terahertz imaging is unlocking unique capabilities for the analysis of cultural heritage artifacts. This paper uses terahertz time-domain imaging for the study of a gilded wooden artifact, providing a means to perform stratigraphic analysis, yielding information about the composition of the artifact, presence of certain materials identifiable through their THz spectral fingerprint, as well as alterations that have been performed over time. Due to the limited information that is available for many historic artifacts, the data that can be obtained through the presented technique can guide proper stewardship of the artifact, informing its long-term preservation.
    Language English
    Publishing date 2024-03-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56913-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Post-synthesis nanostructuration of BSA-Capsaicin nanoparticles generated by sucrose excipient.

    Carriles, Ramón / Zavala-García, Laura E / Nava-Coronel, Sofía / Sánchez-Arreguín, Alejandro / López, Mercedes G / Sánchez-Segura, Lino

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 7549

    Abstract: In the pharmaceutical industry nano-hydrocolloid systems frequently coalesce or present nanoparticle aggregation after a long storage periods. Besides, the lyophilization process used to dry nanoparticles (NPs) produces loss of their original properties ... ...

    Abstract In the pharmaceutical industry nano-hydrocolloid systems frequently coalesce or present nanoparticle aggregation after a long storage periods. Besides, the lyophilization process used to dry nanoparticles (NPs) produces loss of their original properties after dispersion. In this work we evaluated the effect on morphology and physicochemical properties of different protective excipients during drying of bovine serum albumin (BSA) NPs loaded with different concentrations of capsaicin. Capsaicin concentrations of 0, 812, 1625, 2437, and 3250 µg mL
    Language English
    Publishing date 2021-04-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-87241-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Generation of BSA-capsaicin Nanoparticles and Their Hormesis Effect on the

    Sánchez-Arreguin, Alejandro / Carriles, Ramón / Ochoa-Alejo, Neftalí / López, Mercedes G / Sánchez-Segura, Lino

    Molecules (Basel, Switzerland)

    2019  Volume 24, Issue 15

    Abstract: Capsaicin is a chemical compound found in pungent chili peppers ( ...

    Abstract Capsaicin is a chemical compound found in pungent chili peppers (
    MeSH term(s) Capsaicin/chemistry ; Capsaicin/pharmacology ; Cell Line ; Cell Survival/drug effects ; Hormesis ; Humans ; Nanoparticles/chemistry ; Rhodotorula/drug effects ; Rhodotorula/pathogenicity ; Serum Albumin, Bovine/chemistry
    Chemical Substances Serum Albumin, Bovine (27432CM55Q) ; Capsaicin (S07O44R1ZM)
    Language English
    Publishing date 2019-08-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules24152800
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Imaging and SERS Study of the Au Nanoparticles Interaction with HPV and Carcinogenic Cervical Tissues.

    Ceja-Fdez, Andrea / Carriles, Ramon / González-Yebra, Ana Lilia / Vivero-Escoto, Juan / de la Rosa, Elder / López-Luke, Tzarara

    Molecules (Basel, Switzerland)

    2021  Volume 26, Issue 12

    Abstract: In this work, gold NPs were prepared by the Turkevich method, and their interaction with HPV and cancerous cervical tissues were studied by scanning electron microscopy, energy-dispersive x-ray spectroscopy, confocal and multiphoton microscopy and SERS. ... ...

    Abstract In this work, gold NPs were prepared by the Turkevich method, and their interaction with HPV and cancerous cervical tissues were studied by scanning electron microscopy, energy-dispersive x-ray spectroscopy, confocal and multiphoton microscopy and SERS. The SEM images confirmed the presence and localization of the gold NPs inside of the two kinds of tissues. The light absorption of the gold NPs was at 520 nm. However, it was possible to obtain two-photon imaging (red emission region) of the gold NPs inside of the tissue, exciting the samples at 900 nm, observing the morphology of the tissues. The infrared absorption was probably due to the aggregation of gold NPs inside the tissues. Therefore, through the interaction of gold nanoparticles with the HPV and cancerous cervical tissues, a surface enhanced Raman spectroscopy (SERS) was obtained. As preliminary studies, having an average of 1000 Raman spectra per tissue, SERS signals showed changes between the HPV-infected and the carcinogenic tissues; these spectral signatures occurred mainly in the DNA bands, potentially offering a tool for the rapid screening of cancer.
    MeSH term(s) DNA/chemistry ; Female ; Gold/chemistry ; Humans ; Metal Nanoparticles/chemistry ; Microscopy, Electron, Scanning/methods ; Papillomaviridae/isolation & purification ; Papillomaviridae/pathogenicity ; Papillomavirus Infections/complications ; Papillomavirus Infections/pathology ; Papillomavirus Infections/virology ; Spectrum Analysis, Raman/methods ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/diagnostic imaging ; Uterine Cervical Neoplasms/metabolism ; Uterine Cervical Neoplasms/virology
    Chemical Substances Gold (7440-57-5) ; DNA (9007-49-2)
    Language English
    Publishing date 2021-06-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26123758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Post-synthesis nanostructuration of BSA-Capsaicin nanoparticles generated by sucrose excipient

    Ramón Carriles / Laura E. Zavala-García / Sofía Nava-Coronel / Alejandro Sánchez-Arreguín / Mercedes G. López / Lino Sánchez-Segura

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 14

    Abstract: Abstract In the pharmaceutical industry nano-hydrocolloid systems frequently coalesce or present nanoparticle aggregation after a long storage periods. Besides, the lyophilization process used to dry nanoparticles (NPs) produces loss of their original ... ...

    Abstract Abstract In the pharmaceutical industry nano-hydrocolloid systems frequently coalesce or present nanoparticle aggregation after a long storage periods. Besides, the lyophilization process used to dry nanoparticles (NPs) produces loss of their original properties after dispersion. In this work we evaluated the effect on morphology and physicochemical properties of different protective excipients during drying of bovine serum albumin (BSA) NPs loaded with different concentrations of capsaicin. Capsaicin concentrations of 0, 812, 1625, 2437, and 3250 µg mL−1 were used; subsequently, NPs were dried with deionized water (DW), NaCl (DN), sucrose (DS), and not dried (ND). We found that ND, DW, and DN treatments showed a negative effect on the NPs properties; while, DS reduced the aggregation and produced the formation of isolated nanoparticles at higher concentrations of capsaicin (3250 µg mL−1), improving their circular shape, morphometrical parameters, and ζ-potential. The stability of the BSA-capsaicin NPs was associated to complex capsaicin/amino acid/water, in which GLY/GLN, ALA/HIS, ARG, THR, TYR, and Iso/CYS amino acids are involved in the restructuration of capsaicin molecules into the surface of nanoparticles during the drying process. The secondary nanostructuration in the post-synthesis stage can improve the molecular stability of the particles and the capacity of entrapping hydrophobic drugs, like capsaicin.
    Keywords Medicine ; R ; Science ; Q
    Subject code 660
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Two-Photon Excitation Spectroscopy of Silicon Quantum Dots and Ramifications for Bio-Imaging.

    Furey, Brandon J / Stacy, Benjamin J / Shah, Tushti / Barba-Barba, Rodrigo M / Carriles, Ramon / Bernal, Alan / Mendoza, Bernardo S / Korgel, Brian A / Downer, Michael C

    ACS nano

    2022  Volume 16, Issue 4, Page(s) 6023–6033

    Abstract: Two-photon excitation in the near-infrared (NIR) of colloidal nanocrystalline silicon quantum dots (nc-SiQDs) with photoluminescence also in the NIR has potential opportunities in the field of deep biological imaging. Spectra of the degenerate two-photon ...

    Abstract Two-photon excitation in the near-infrared (NIR) of colloidal nanocrystalline silicon quantum dots (nc-SiQDs) with photoluminescence also in the NIR has potential opportunities in the field of deep biological imaging. Spectra of the degenerate two-photon absorption (2PA) cross section of colloidal nc-SiQDs are measured using two-photon excitation over a spectral range 1.46 < ℏω < 1.91 eV (wavelength 850 > λ > 650 nm) above the two-photon band gap E<sub>g</sub><sup>(QD)</sup>/2, and at a representative photon energy ℏω = 0.99 eV (λ = 1250 nm) below this gap. Two-photon excited photoluminescence (2PE-PL) spectra of nc-SiQDs with diameters d = 1.8 ± 0.2 nm and d = 2.3 ± 0.3 nm, each passivated with 1-dodecene and dispersed in toluene, are calibrated in strength against 2PE-PL from a known concentration of Rhodamine B dye in methanol. The 2PA cross section is observed to be smaller for the smaller diameter nanocrystals, and the onset of 2PA is observed to be blue shifted from the two-photon indirect band gap of bulk Si, as expected for quantum confinement of excitons. The efficiencies of nc-SiQDs for bioimaging using 2PE-PL are simulated in various biological tissues and compared to efficiencies of other quantum dots and molecular fluorophores and found to be comparable or superior at greater depths.
    MeSH term(s) Silicon/chemistry ; Quantum Dots/chemistry ; Photons ; Nanoparticles/chemistry ; Spectrum Analysis
    Chemical Substances Silicon (Z4152N8IUI)
    Language English
    Publishing date 2022-03-31
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ISSN 1936-086X
    ISSN (online) 1936-086X
    DOI 10.1021/acsnano.1c11428
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Generation of BSA-capsaicin Nanoparticles and Their Hormesis Effect on the Rhodotorula mucilaginosa Yeast

    Alejandro Sánchez-Arreguin / Ramón Carriles / Neftalí Ochoa-Alejo / Mercedes G. López / Lino Sánchez-Segura

    Molecules, Vol 24, Iss 15, p

    2019  Volume 2800

    Abstract: Capsaicin is a chemical compound found in pungent chili peppers ( Capsicum spp.). In biotechnology, capsaicin has been proposed as a pathogen control; however, its low solubility in water and high instability limits its uses. The aim of this work was to ... ...

    Abstract Capsaicin is a chemical compound found in pungent chili peppers ( Capsicum spp.). In biotechnology, capsaicin has been proposed as a pathogen control; however, its low solubility in water and high instability limits its uses. The aim of this work was to study the effect of high concentrations of capsaicin on the synthesis of nanoparticles and to evaluate their inhibitory effect on the growth of Rhodotorula mucilaginosa yeast. Bovine serum albumin (BSA)-capsaicin nanoparticles were formulated at 0, 16.2, 32.5, 48.7 and 65.0 µg of capsaicin per mg of BSA. Nanoparticle properties were evaluated and they were added to cultures of R. mucilaginosa to quantify their effect on cell viability. We found that increased capsaicin levels caused several changes to the physicochemical parameters, probably due to changes in the hydrophobicity sites of the albumin during the nanostructuration. The administration of nanoparticles to cultures of R. mucilaginosa produced a maximal viability with nanoparticles at 16.2 µg/mg; on the contrary, nanoparticles at 65.0 µg/mg caused maximal cell death. R. mucilaginosa cells displayed a hormesis effect in response to the nanoparticle dose concentration. The nanoparticles showed different responses during the uptake process, probably as a consequence of the nanostructural properties of capsaicin in the BSA molecules.
    Keywords capsaicin ; bovine serum albumin ; nanoparticles ; fungi ; Rhodoturola ; hormesis ; Organic chemistry ; QD241-441
    Subject code 500
    Language English
    Publishing date 2019-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Imaging and SERS Study of the Au Nanoparticles Interaction with HPV and Carcinogenic Cervical Tissues

    Andrea Ceja-Fdez / Ramon Carriles / Ana Lilia González-Yebra / Juan Vivero-Escoto / Elder de la Rosa / Tzarara López-Luke

    Molecules, Vol 26, Iss 3758, p

    2021  Volume 3758

    Abstract: In this work, gold NPs were prepared by the Turkevich method, and their interaction with HPV and cancerous cervical tissues were studied by scanning electron microscopy, energy-dispersive x-ray spectroscopy, confocal and multiphoton microscopy and SERS. ... ...

    Abstract In this work, gold NPs were prepared by the Turkevich method, and their interaction with HPV and cancerous cervical tissues were studied by scanning electron microscopy, energy-dispersive x-ray spectroscopy, confocal and multiphoton microscopy and SERS. The SEM images confirmed the presence and localization of the gold NPs inside of the two kinds of tissues. The light absorption of the gold NPs was at 520 nm. However, it was possible to obtain two-photon imaging (red emission region) of the gold NPs inside of the tissue, exciting the samples at 900 nm, observing the morphology of the tissues. The infrared absorption was probably due to the aggregation of gold NPs inside the tissues. Therefore, through the interaction of gold nanoparticles with the HPV and cancerous cervical tissues, a surface enhanced Raman spectroscopy (SERS) was obtained. As preliminary studies, having an average of 1000 Raman spectra per tissue, SERS signals showed changes between the HPV-infected and the carcinogenic tissues; these spectral signatures occurred mainly in the DNA bands, potentially offering a tool for the rapid screening of cancer.
    Keywords gold nanoparticles ; HPV ; cervical cancer ; two-photon imaging ; confocal microscopy ; multiphoton microscopy ; Organic chemistry ; QD241-441
    Subject code 540
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Book ; Online: Im$\{\chi^{(3)}\}$ spectra of 110-cut GaAs, GaP, and Si near the two-photon absorption band edge

    Furey, Brandon J / Barba-Barba, Rodrigo M. / Carriles, Ramon / Bernal, Alan / Mendoza, Bernardo S. / Downer, Michael C.

    2021  

    Abstract: Spectra of the degenerate two-photon absorption coefficient $\beta(\omega)$, anisotropy parameter $\sigma(\omega)$, and dichroism parameter $\delta(\omega) = \big[\sigma(\omega) + 2\eta(\omega)\big]/2$ of crystalline 110-cut GaAs, GaP, and Si at 300 K ... ...

    Abstract Spectra of the degenerate two-photon absorption coefficient $\beta(\omega)$, anisotropy parameter $\sigma(\omega)$, and dichroism parameter $\delta(\omega) = \big[\sigma(\omega) + 2\eta(\omega)\big]/2$ of crystalline 110-cut GaAs, GaP, and Si at 300 K were measured using femtosecond pump-probe modulation spectroscopy over an excitation range in the vicinity of each material's half-band gap $E_g/2$ (overall $0.62 < \hbar \omega < 1.91$ eV, or $2000 > \lambda > 650$ nm). Together these three parameters completely characterize the three independent components of the imaginary part of the degenerate third-order nonlinear optical susceptibility tensor $\mathrm{Im}\{\chi^{(3)}_{abcd}(\omega)\}$. In direct-gap GaAs, these components peak at $\hbar \omega \approx 0.78 E_g$ which is close to the peak at $\hbar \omega = 0.71 E_g$ predicted by the Jones-Reiss phenomenological model. The dispersion is comparable to ab initio calculations. In indirect-gap GaP and Si, these components tend to increase with $\hbar \omega$ over our tuning range. In Si, the dispersion differs significantly from predictions of semi-empirical models and ab initio calculations do not account for transitions below the two-photon direct band gap, motivating further investigation. Kleinman symmetry was observed to be broken in all three materials. We also note anomalies observed and their possible origins, emphasizing the advantages of a 2-beam experiment in identifying the contribution of various nonlinear effects.

    Comment: 62 pages, 63 figures, 86 references. The following article has been accepted by J. Appl. Phys. After it is published, it will be found at https://aip.scitation.org/journal/jap; added references, changes to manuscript after peer review, minor changes to supplementary material, and typos corrected
    Keywords Condensed Matter - Materials Science ; Physics - Optics
    Subject code 535
    Publishing date 2021-02-14
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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