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  1. Article ; Online: Letter to the editor: Effects of self-management interventions for cancer patients with pain: A systematic review of randomized controlled trials.

    Huang, Xiaolu / Ran, Niandong

    Journal of clinical nursing

    2023  Volume 33, Issue 3, Page(s) 1222–1223

    MeSH term(s) Humans ; Self-Management ; Randomized Controlled Trials as Topic ; Pain ; Pain Management ; Neoplasms/therapy
    Language English
    Publishing date 2023-10-11
    Publishing country England
    Document type Systematic Review ; Letter
    ZDB-ID 1159483-4
    ISSN 1365-2702 ; 0962-1067 ; 1752-9816
    ISSN (online) 1365-2702
    ISSN 0962-1067 ; 1752-9816
    DOI 10.1111/jocn.16903
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3764: Show issues Location:
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  2. Article ; Online: Efficacy and safety of telitacicept in patients with lupus nephritis: a single-center, real-world retrospective study.

    Huang, Xiaolu / Lin, Fuan / Chen, Hongpu

    Clinical and experimental nephrology

    2024  

    Abstract: Background: Telitacicept, an innovative drug used for the treatment of systemic lupus erythematosus (SLE), can effectively control disease progression and achieve favorable outcomes. While case reports have mentioned the use of Telitacicept in lupus ... ...

    Abstract Background: Telitacicept, an innovative drug used for the treatment of systemic lupus erythematosus (SLE), can effectively control disease progression and achieve favorable outcomes. While case reports have mentioned the use of Telitacicept in lupus nephritis (LN) treatment, its safety and efficacy in treating patients with LN have not been explored. Therefore, in this study, we aimed to evaluate the safety and efficacy of Telitacicept in managing patients with LN.
    Methods: In a single-center, real-world retrospective study, 30 LN patients with poor response or adverse reactions to conventional glucocorticoids at our Hospital were enrolled to receive Telitacicept. Patients were administered 160 mg of Telitacicept subcutaneously once a week for at least 24 weeks in addition to standard treatment. We assessed the SLE responder index-4 (SRI-4) at the beginning and the end of the treatment period, measured laboratory test indicators at 3, 6, and 9 months, and observed the occurrence of adverse events in these patients.
    Results: The SRI-4 response rate was 86.67% (n = 26), with a significantly lower systemic lupus erythematosus disease activity index (SLEDAI) score compared to the baseline. Post Telitacicept treatment, glucocorticoid intake of patients with LN significantly reduced from 50 (IQR:40, 51.25) at baseline to 10 (IQR:5,10) at the endpoint (Z = - 6.547, p < 0.001). Patients with LN showed significantly improved urine occult blood levels after Telitacicept therapy. While the complement (C3 and C4) contents increased, immunoglobulins (IgG, IgA and IgM) reduced markedly (p < 0.001). The negative rate of dsDNA reached 26.67% and adverse events were alleviated post treatment. Only two cases of LN-related adverse reactions were reported, including herpes and infectious fever, respectively. Telitacicept primarily serves as an agent for the induction of remission therapy, with an attainment of complete remission rate standing at a commendable 73.3%.
    Conclusions: Telitacicept treatment reduced disease severity in patients with LN. The initial clinical trial provided supportive evidence for the effectiveness and safety of Telitacicept as a viable treatment option for LN, allowing a reduction in the daily glucocorticoid intake while maintaining a good safety profile, and improving hypocomplementation in LN management.
    Language English
    Publishing date 2024-04-13
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1338768-6
    ISSN 1437-7799 ; 1342-1751
    ISSN (online) 1437-7799
    ISSN 1342-1751
    DOI 10.1007/s10157-024-02501-x
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    Zs.A 4922: Show issues Location:
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  3. Article: MSCTA imaging analysis of autologous arteriovenous fistula dysfunction in maintenance hemodialysis patients.

    Wang, Yingjie / Qin, Yanlei / Huang, Xiaolu / Liu, Weihong

    American journal of translational research

    2024  Volume 16, Issue 3, Page(s) 955–963

    Abstract: Objective: To observe the multi-slice spiral CT angiography (MSCTA) imaging features of arteriovenous fistula dysfunction in patients undergoing maintenance hemodialysis and analyze the significance of the imaging examination.: Methods: Altogether 90 ...

    Abstract Objective: To observe the multi-slice spiral CT angiography (MSCTA) imaging features of arteriovenous fistula dysfunction in patients undergoing maintenance hemodialysis and analyze the significance of the imaging examination.
    Methods: Altogether 90 patients with end-stage renal disease treated by maintenance hemodialysis in General Hospital of China Resources & Wisco from June 2020 to February 2023 were divided into a normal function group (n=68) and a dysfunction group (n=22) according to the function of autogenous arteriovenous fistula. The clinical data of the two groups were recorded. The MSCTA was performed in each patient, and the manifestations of arteriovenous fistula dysfunction were analyzed. Additionally, the vascular access stenosis, vascular access lumen stenosis, arteriovenous diameter, blood flow, and hemodynamic indices were tested, and the value of MSCTA in predicting arteriovenous fistula function was analyzed by Logistic regression.
    Results: The degree of vascular access stenosis and vascular access lumen stenosis in the normal group were less than those in the dysfunctional group (P<0.05). The arteriovenous diameter, blood flow, blood flow velocity at anastomotic vein end, dialysis adequacy (spKt/V), and von Willebrand factor (vWF) function in the normal group were larger than those in the dysfunction group, and the radial artery shear force was lower than in the dysfunction group, with statistical significance (P<0.05). Among the arteriovenous fistula dysfunction, there were 3 patients with anastomotic + outflow vein stenosis, 4 patients with outflow vein stenosis, 9 patients with inflow artery + anastomosis + outflow vein stenosis, and 6 patients with superior vena cava stenosis. Logistic regression analysis showed that slow blood flow velocity at the venous end of anastomosis and high shear force of radial artery were influencing factors of arteriovenous fistula dysfunction, and the area under ROC curve of blood flow velocity at the venous end of anastomosis plus shear force of radial artery was 0.93, with a sensitivity of 0.87 and a specificity of 0.85.
    Conclusion: MSCTA can be used to evaluate the dysfunction of autologous arteriovenous fistula in patients undergoing maintenance hemodialysis, and provide important reference information for the formulation of the next best clinical treatment plan.
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
    DOI 10.62347/YEGN9292
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  4. Article ; Online: Closed-loop process for selective leaching and recovery of palladium from spent auto-exhaust catalysts using iodotrihalide ionic liquids.

    Yin, Xiaolu / Li, Jun / Liu, Xiaoxia / Huang, Kaiqiang / Yang, Yanzhao

    Journal of hazardous materials

    2024  Volume 467, Page(s) 133665

    Abstract: The recovery of palladium from spent auto-exhaust catalysts (SAE-catalysts) is of great significance for resource sustainability. Herein, we proposed an efficient closed-loop leaching and recovery method for palladium from SAE-catalysts using ... ...

    Abstract The recovery of palladium from spent auto-exhaust catalysts (SAE-catalysts) is of great significance for resource sustainability. Herein, we proposed an efficient closed-loop leaching and recovery method for palladium from SAE-catalysts using iodotrihalide ionic liquids (ILs). Recovery design was explored aimed at green leaching and process simplification. Iodotrihalide ILs exhibited exceptional performance in terms of leaching efficiency (99.1%), selectivity (selectivity > 6.8 ×10
    Language English
    Publishing date 2024-02-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2024.133665
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  5. Article ; Online: Conservative treatment of perforation during endoscopic submucosal dissection of lower rectal tumor by use of an endotracheal tube.

    Huang, Xiaojie / Lin, Xiaolu / Deng, Wanyin

    Gastrointestinal endoscopy

    2023  Volume 97, Issue 6, Page(s) 1167–1168

    MeSH term(s) Humans ; Endoscopic Mucosal Resection/adverse effects ; Conservative Treatment ; Rectal Neoplasms/surgery ; Rectal Neoplasms/pathology ; Intestinal Mucosa/pathology ; Intubation, Intratracheal ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.01.029
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 283: Show issues Location:
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    Zs.MO 519: Show issues

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  6. Article ; Online: Visualization and Quantification of the Dynamics of Actin Filaments in Arabidopsis Pollen Tubes.

    Lu, Qiaonan / Liu, Xiaonan / Qu, Xiaolu / Huang, Shanjin

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2604, Page(s) 285–295

    Abstract: The actin cytoskeleton plays an essential role in the regulation of polarized pollen tube growth, and its functions are dictated by its spatial organization and dynamics. Here we describe an assay to monitor the dynamics of actin filaments decorated with ...

    Abstract The actin cytoskeleton plays an essential role in the regulation of polarized pollen tube growth, and its functions are dictated by its spatial organization and dynamics. Here we describe an assay to monitor the dynamics of actin filaments decorated with Lifeact-mEGFP in Arabidopsis pollen tubes using spinning disk confocal microscopy and measuring the parameters associated with their dynamics. The method allows us to assess the dynamics of actin filaments in growing Arabidopsis pollen tubes.
    MeSH term(s) Arabidopsis ; Pollen Tube ; Arabidopsis Proteins ; Actins ; Actin Cytoskeleton
    Chemical Substances Arabidopsis Proteins ; Actins
    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2867-6_23
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  7. Article ; Online: Resected specimen extraction using a medical glove in endoscopic submucosal dissection of a large gastric submucosal tumor (with video).

    Lin, Xiaolu / Huang, Xiaojie / Chen, Guifen / Yang, Shijie / Deng, Wanyin

    Gastrointestinal endoscopy

    2023  Volume 98, Issue 3, Page(s) 449–450

    MeSH term(s) Humans ; Endoscopic Mucosal Resection ; Stomach Neoplasms/surgery ; Stomach Neoplasms/pathology ; Gastroscopy ; Gastric Mucosa/surgery ; Gastric Mucosa/pathology
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Video-Audio Media ; Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.05.004
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  8. Article: NUF2

    Jiang, Feng / Huang, Xiaolu / Yang, Xiang / Zhou, Huixin / Wang, Yumin

    Frontiers in oncology

    2022  Volume 12, Page(s) 795971

    Abstract: Aberrant expression of the gene encoding the Ndc80 kinetochore complex component ( ...

    Abstract Aberrant expression of the gene encoding the Ndc80 kinetochore complex component (
    Language English
    Publishing date 2022-06-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.795971
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  9. Article ; Online: Effectiveness of acupuncture-related therapies on schizophrenia: a Bayesian network Meta-analysis.

    Zhaohan, Huang / Yuan, Fang / Xiaolu, Wang / Yue, Han / Qi, Y U / Tong, Wang

    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

    2023  Volume 43, Issue 2, Page(s) 239–251

    Abstract: Objective: To create the hierarchical model for the comparison of efficacy of different ATs for schizophrenia.: Methods: PubMed, Web of Science, Embase, The Cochrane Library, ClinicalTrials, China National Knowledge Infrastructure Database, China ... ...

    Abstract Objective: To create the hierarchical model for the comparison of efficacy of different ATs for schizophrenia.
    Methods: PubMed, Web of Science, Embase, The Cochrane Library, ClinicalTrials, China National Knowledge Infrastructure Database, China Science and Technology Journal Database, Wanfang Database, and SinoMed were searched using a specified search strategy to identify relevant studies up to December 2021. The data were extracted independently by two reviewers. The quality of included trials was evaluated based on the guidelines of "Cochrane Handbook for Systematic Reviews of Interventions". Bayesian network meta-analysis was conducted by statistical analysis software Addis 1.16.6 and Stata 15.1.
    Results: In total, 60 randomized controlled trials covering 4810 patients were enrolled. The network meta-analysis result showed that Body Acupuncture (BA), BA + Electro-acupuncture (EA), Scalp Acupuncture (SA) + EA, Auricular Acupuncture (AA), Low-dose medication and Acupuncture (LA), Acupoint Injection (AI), and Acupoint Catgut Embedding (ACE), when combined with Western Medications (WM), demonstrated a better clinical effect at improving the symptoms of schizophrenia, compared to WM alone. Results of rank probability showed that BA, when combined with WM, was the most optimal AT for schizophrenia at decreasing three aspects of PANSS scale score.
    Conclusions: Acupuncture-related therapies help improve the symptoms of schizophrenia, and BA combined with WM may be a better therapy for schizophrenia. This study has been registered on the "PROSPERO" website, and the registration number is CRD42021227403.
    MeSH term(s) Humans ; Network Meta-Analysis ; Bayes Theorem ; Schizophrenia/therapy ; Systematic Reviews as Topic ; Acupuncture Therapy/methods ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2023-03-16
    Publishing country China
    Document type Meta-Analysis ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603186-9
    ISSN 2589-451X ; 0254-6272 ; 0255-2922
    ISSN (online) 2589-451X ; 0254-6272
    ISSN 0255-2922
    DOI 10.19852/j.cnki.jtcm.20221226.001
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  10. Article ; Online: Analysis of heavy metal and polycyclic aromatic hydrocarbon pollution characteristics of a typical metal rolling industrial site based on data mining.

    Li, De'an / Deng, Yirong / Liu, LiLi / Wang, Jun / Huang, Zaoquan / Zhang, Xiaolu

    Environmental geochemistry and health

    2024  Volume 46, Issue 5, Page(s) 146

    Abstract: With the transformation and upgrading of industries, the environmental problems caused by industrial residual contaminated sites are becoming increasingly prominent. Based on actual investigation cases, this study analyzed the soil pollution status of a ... ...

    Abstract With the transformation and upgrading of industries, the environmental problems caused by industrial residual contaminated sites are becoming increasingly prominent. Based on actual investigation cases, this study analyzed the soil pollution status of a remaining sites of the copper and zinc rolling industry, and found that the pollutants exceeding the screening values included Cu, Ni, Zn, Pb, total petroleum hydrocarbons and 6 polycyclic aromatic hydrocarbon monomers. Based on traditional analysis methods such as the correlation coefficient and spatial distribution, combined with machine learning methods such as SOM + K-means, it is inferred that the heavy metal Zn/Pb may be mainly related to the production history of zinc rolling. Cu/Ni may be mainly originated from the production history of copper rolling. PAHs are mainly due to the incomplete combustion of fossil fuels in the melting equipment. TPH pollution is speculated to be related to oil leakage during the industrial use period and later period of vehicle parking. The results showed that traditional analysis methods can quickly identify the correlation between site pollutants, while SOM + K-means machine learning methods can further effectively extract complex hidden relationships in data and achieve in-depth mining of site monitoring data.
    MeSH term(s) Copper/analysis ; Polycyclic Aromatic Hydrocarbons/analysis ; Lead/analysis ; Soil Pollutants/analysis ; Metals, Heavy/analysis ; Zinc/analysis ; Environmental Pollution/analysis ; Soil ; Environmental Pollutants/analysis ; Data Mining ; Environmental Monitoring/methods ; China ; Risk Assessment
    Chemical Substances Copper (789U1901C5) ; Polycyclic Aromatic Hydrocarbons ; Lead (2P299V784P) ; Soil Pollutants ; Metals, Heavy ; Zinc (J41CSQ7QDS) ; Soil ; Environmental Pollutants
    Language English
    Publishing date 2024-04-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 52039-1
    ISSN 1573-2983 ; 0142-7245 ; 0269-4042
    ISSN (online) 1573-2983
    ISSN 0142-7245 ; 0269-4042
    DOI 10.1007/s10653-024-01928-1
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