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Article ; Online: Identifying Predictors of Momentary Negative Affect and Depression Severity in Adolescents with Autism: An Exploratory Ecological Momentary Assessment Study.

Dallman, Aaron R / Bailliard, Antoine / Harrop, Clare

Journal of autism and developmental disorders

2021 Volume 52, Issue 1, Page(s) 291–303

Abstract: ... of social interaction and enjoyment of the current activity (p < 0.05). Additionally, affective instability predicted ...

Abstract	Depression is a common comorbidity in autism spectrum disorder (ASD). Little is known about risk factors for depression and depressive symptoms in this population. Ecological momentary assessment (EMA) has been used in the typically developing population to identify risk factors for depression, but has been rarely applied in ASD populations. In this exploratory study, 17 autistic adolescents participated in an EMA protocol in which they reported on their current activities and emotions six times per day for seven consecutive days. Results suggested that negative affect is predicted by momentary quality of social interaction and enjoyment of the current activity (p < 0.05). Additionally, affective instability predicted depressive symptoms. These results provide insights into risk factors for depression in this vulnerable population.
MeSH term(s)	Adolescent ; Affect ; Autism Spectrum Disorder ; Autistic Disorder ; Depression/diagnosis ; Ecological Momentary Assessment ; Emotions ; Humans
Language	English
Publishing date	2021-03-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	391999-7
ISSN	1573-3432 ; 0162-3257
ISSN (online)	1573-3432
ISSN	0162-3257
DOI	10.1007/s10803-021-04935-8
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Article ; Online: Inspection of chicken wings and legs for animal welfare monitoring using X-ray computed tomography, visual examination, and histopathology.

Libera, Kacper / Valadian, Roozbeh / Vararattanavech, Patiharn / Dasari, Sri Nithya / Dallman, Timothy J / Weerts, Erik / Lipman, Len

Poultry science

2023 Volume 103, Issue 3, Page(s) 103403

Abstract: In broiler chickens, fractures of wings and legs are recorded at poultry slaughterhouses based on the time of occurrence. Prekilling (PRE) fractures occur before the death of animal, so the chicken was still able to experience pain and distress ... ...

Abstract	In broiler chickens, fractures of wings and legs are recorded at poultry slaughterhouses based on the time of occurrence. Prekilling (PRE) fractures occur before the death of animal, so the chicken was still able to experience pain and distress associated with the injury (an animal welfare issue). Postkilling (POST) fractures occur when the chickens are deceased and fully bled-out and consequently unable to feel pain (not an animal welfare issue). Current practice dictates that fractures are recognized visually and recorded by the animal welfare officers as mandated by European Union and/or national regulations. However, new potential monitoring solutions are desired since human inspection suffers from some significant limitations including subjectivism and fatigue. One possible solution in detecting injuries is X-ray computed tomography (CT) scanning and in this study we aim to evaluate the potential of CT scanning and visual inspection in detecting limb fractures and their causes. Eighty-three chicken wings and 60 chicken legs (n = 143) were collected from a single slaughterhouse and classified by an animal welfare officer as PRE, POST or healthy (HEAL). Samples were photographed and CT scanned at a veterinary hospital. The interpretation of CT scans along with photographs took place in 3 rounds (1. CT scans only, 2. CT scans + photographs, 3. photographs only) and was performed independently by 3 veterinarians. The consistency of the interpretation in 3 rounds was compared with the animal welfare officer's classification. Furthermore, selected samples were also analyzed by histopathological examination due to questionability of their classification (PRE/POST). In questionable samples, presence of hemorrhages was confirmed, thus they fit better as PRE. The highest consistency between raters was obtained in the 2nd round, indicating that interpretation accuracy was the highest when CT scans were combined with photographs. These results indicate that CT scanning in combination with visual inspection can be used in detecting limbs fracture and potentially applied as a tool to monitor animal welfare in poultry slaughterhouses in the future.
MeSH term(s)	Animals ; Humans ; Chickens ; Tomography, X-Ray Computed/veterinary ; Extremities ; Fractures, Bone/veterinary ; Animal Welfare ; Pain/veterinary
Language	English
Publishing date	2023-12-27
Publishing country	England
Document type	Journal Article
ZDB-ID	242586-5
ISSN	1525-3171 ; 0032-5791
ISSN (online)	1525-3171
ISSN	0032-5791
DOI	10.1016/j.psj.2023.103403
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Article: Vitamin e deficiency in premature infants: interaction with iron.

Dallman, P R

The Western journal of medicine

2008 Volume 124, Issue 1, Page(s) 49

Language	English
Publishing date	2008-08-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	189235-6
ISSN	1476-2978 ; 0093-0415 ; 0008-1264
ISSN (online)	1476-2978
ISSN	0093-0415 ; 0008-1264
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Article ; Online: Behavioral Inflexibility Across Two Neurogenetic Conditions: Down Syndrome and Fragile X Syndrome.

Harrop, Clare / Dallman, Aaron R / Lecavalier, Luc / Bodfish, James W / Boyd, Brian A

American journal on intellectual and developmental disabilities

2021 Volume 126, Issue 5, Page(s) 409–420

Abstract: ... higher in FXS+ASD than both FXS only and DS (p <.001). Most endorsed items were similar across the three ...

Abstract	Behavioral inflexibility (BI) has been highlighted to occur across genetic and neurodevelopmental disorders. This study characterized BI in two common neurogenetic conditions: Fragile X syndrome (FXS) and Down syndrome (DS). Caregivers of children with FXS (N = 56; with ASD = 28; FXS only = 28) and DS (N = 146) completed the Behavioral Inflexibility Scale (BIS) via an online survey. Total BIS scores were higher in FXS+ASD than both FXS only and DS (p <.001). Most endorsed items were similar across the three groups, but scores were higher in the FXS+ASD group. In all groups, BI associated with other clinical variables (receptive behaviors, anxiety, social communication). The current data suggest that BI is variable across neurogenetic conditions and higher in individuals with comorbid ASD.
MeSH term(s)	Anxiety ; Autism Spectrum Disorder ; Child ; Communication ; Down Syndrome/genetics ; Fragile X Syndrome/genetics ; Humans
Language	English
Publishing date	2021-08-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2477909-X
ISSN	1944-7558 ; 1944-7515
ISSN (online)	1944-7558
ISSN	1944-7515
DOI	10.1352/1944-7558-126.5.409
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Article ; Online: Perioperative allogenic blood transfusions are associated with increased fracture related infection rates, but not nonunion in operatively treated distal femur fractures.

Haase, Douglas R / Haase, Lucas R / Moon, Tyler J / Dallman, Johnathan / Vance, Dylan / Benedick, Alexander / Ochenjele, George / Napora, Joshua K / Wise, Brent T

Injury

2023 Volume 54, Issue 7, Page(s) 110754

Abstract: ... with nonunion (13% vs 12%, P = 0.87), but was associated with FRI (15% vs 4%, P<0.001). Binary ... blood transfusions and FRI: total transfusion ≥2 U PRBC RR= 3.47(1.29, 8.10, P = 0.02), ≥3 RR= 6.99 (3.01, 12.40, P<0 ... 001), and ≥4 RR= 8.94 (4.03, 14.42, P<0.001).: Discussion: In patients undergoing operative ...

Abstract	Introduction: Distal femur fractures are common injuries that remain difficult for orthopedic surgeons to treat. High complication rates, including nonunion rates as high as 24% and infection rates of 8%, can lead to increased morbidity for these patients. Allogenic blood transfusions have previously been identified as risk factors for infection in total joint arthroplasty and spinal fusion surgeries. No studies have explored the relationship between blood transfusions and fracture related infection (FRI) or nonunion in distal femur fractures. Methods: 418 patients with operatively treated distal femur fractures at two level I trauma centers were retrospectively reviewed. Patient demographics were collected including age, gender, BMI, medical comorbidities, and smoking. Injury and treatment information was also collected including open fracture, polytrauma status, implant, perioperative transfusions, FRI, and nonunion. Patients with less than three months of follow up were excluded. Results: 366 patients were included in final analysis. One hundred thirty-nine (38%) patients received a perioperative blood transfusion. Forty-seven (13%) nonunions and 30 (8%) FRI were identified. Allogenic blood transfusion was not associated with nonunion (13% vs 12%, P = 0.87), but was associated with FRI (15% vs 4%, P<0.001). Binary logistic regression analysis identified a dose dependent relationship between number of perioperative blood transfusions and FRI: total transfusion ≥2 U PRBC RR= 3.47(1.29, 8.10, P = 0.02), ≥3 RR= 6.99 (3.01, 12.40, P<0.001), and ≥4 RR= 8.94 (4.03, 14.42, P<0.001). Discussion: In patients undergoing operative treatment of distal femur fractures, perioperative blood transfusions are associated with increased risk of fracture related infection, but not the development of a nonunion. This risk association increases in a dose-dependent relationship with increasing total blood transfusions received.
MeSH term(s)	Humans ; Retrospective Studies ; Femoral Fractures, Distal ; Treatment Outcome ; Femoral Fractures/epidemiology ; Femoral Fractures/surgery ; Femoral Fractures/etiology ; Femur/surgery ; Fracture Fixation, Internal/adverse effects ; Fracture Healing
Language	English
Publishing date	2023-05-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	218778-4
ISSN	1879-0267 ; 0020-1383
ISSN (online)	1879-0267
ISSN	0020-1383
DOI	10.1016/j.injury.2023.04.041
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Zs.A 778: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Doing Occupational Justice: A Central Dimension of Everyday Occupational Therapy Practice.

Bailliard, Antoine L / Dallman, Aaron R / Carroll, Amanda / Lee, Ben D / Szendrey, Susan

Canadian journal of occupational therapy. Revue canadienne d'ergotherapie

2020 Volume 87, Issue 2, Page(s) 144–152

Abstract: ... of intervention" (AOTA, 2014, p. S9).: Key issues.: Despite the increasing focus on justice ...

Abstract	Background.: The Canadian Association of Occupational Therapists (CAOT) and the American Occupational Therapy Association (AOTA) state that occupational justice is part of the domain of occupational therapy and that occupational justice is "an aspect of contexts and environments and an outcome of intervention" (AOTA, 2014, p. S9). Key issues.: Despite the increasing focus on justice in the occupational therapy and the occupational science literature, many practitioners in traditional settings do not see its relevance to their everyday practice (Galvin, Wilding, & Whiteford, 2011) or have difficulty envisioning how to enact a justice-informed practice. Purpose.: This paper demonstrates how occupational justice is germane to all settings of occupational therapy, and how it can be enacted at micro, meso, and macro levels of occupational therapy practice. Implications.: We argue that occupational therapy is a justice-oriented profession at its core and will discuss how occupational justice can be enacted at all levels of practice.
MeSH term(s)	Humans ; Occupational Therapy/organization & administration ; Occupational Therapy/standards ; Patient-Centered Care/organization & administration ; Politics ; Social Justice ; Societies, Scientific
Language	English
Publishing date	2020-01-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	417302-8
ISSN	1911-9828 ; 0008-4174 ; 0315-1026
ISSN (online)	1911-9828
ISSN	0008-4174 ; 0315-1026
DOI	10.1177/0008417419898930
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Article ; Online: Whole-genome sequencing revealed concurrent outbreaks of shigellosis in the English Orthodox Jewish Community caused by multiple importations of Shigella sonnei from Israel.

Rew, Vanessa / Mook, Piers / Trienekens, Suzan / Baker, Kate S / Dallman, Timothy J / Jenkins, Claire / Crook, Paul D / Thomson, Nicholas R

Microbial genomics

2018 Volume 4, Issue 3

Abstract: ... of Shigella sonnei linked to the Orthodox Jewish Community (OJC). Ultimately, 52 cases of S. sonnei phage type (PT) P ...

Abstract	In December 2013, Public Health England (PHE) observed an increase in the number of cases of Shigella sonnei linked to the Orthodox Jewish Community (OJC). Ultimately, 52 cases of S. sonnei phage type (PT) P and PT7 were notified between November 2013 and July 2014. Whole-genome sequencing (WGS) was performed on a HiSeq 2500 platform (Illumina) on isolates of S. sonnei submitted to PHE during the investigation. Quality trimmed sequence reads were mapped to a reference genome using BWA-MEM, and single-nucleotide polymorphisms (SNPs) were identified using GATK2. Analysis of the core genome SNP positions (>90 % consensus, minimum depth 10×, MQ≥30) revealed that isolates linked to the outbreak could be categorized as members of distinct monophyletic clusters (MPCs) representing concurrent regional outbreaks occurring in the OJCs across the United Kingdom. A dated phylogeny predicted the date of the most recent common ancestor of the MPCs to be approximately 3.1 years previously [95 % highest posterior density (HPD), 2.4-3.4]. Isolates of S. sonnei from cases from the OJCs in Israel included in the phylogeny, branched from nodes basal to the UK OJC outbreak clusters, indicating they were ancestral to the UK OJC isolates, and that the UK isolates represented multiple importations of S. sonnei into the UK population from Israel. The level of discrimination exhibited by WGS facilitated the identification of clusters of isolates within the closely related bacterial populations circulating in the OJC that may be linked to a unique point sources or transmission routes, thus enabling a more appropriate public health response and targeted interventions.
MeSH term(s)	Disease Outbreaks ; Dysentery, Bacillary/epidemiology ; Dysentery, Bacillary/genetics ; England/epidemiology ; Female ; Genome, Bacterial ; Humans ; Jews ; Male ; Polymorphism, Single Nucleotide ; Shigella sonnei/genetics ; Shigella sonnei/isolation & purification
Language	English
Publishing date	2018-03-27
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2835258-0
ISSN	2057-5858 ; 2057-5858
ISSN (online)	2057-5858
ISSN	2057-5858
DOI	10.1099/mgen.0.000170
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Article ; Online: Linkage of Whole Genome Sequencing, Epidemiological, and Clinical Data to Understand the Genetic Diversity and Clinical Outcomes of Shigella flexneri among Men Who Have Sex with Men in England.

Mitchell, Holly D / Thomson, Nicholas R / Jenkins, Claire / Dallman, Timothy J / Painset, Anaïs / Kirwan, Peter / Delpech, Valerie / Mikhail, Amy F W / Field, Nigel / Hughes, Gwenda

Microbiology spectrum

2021 Volume 9, Issue 3, Page(s) e0121321

Abstract: The public health value of whole genome sequencing (WGS) ... ...

Abstract	The public health value of whole genome sequencing (WGS) for
MeSH term(s)	Adolescent ; Adult ; Aged ; Anti-Bacterial Agents/therapeutic use ; Azithromycin/therapeutic use ; Contact Tracing ; Disease Outbreaks/statistics & numerical data ; Drug Resistance, Bacterial/genetics ; Dysentery, Bacillary/epidemiology ; Dysentery, Bacillary/microbiology ; Dysentery, Bacillary/transmission ; England/epidemiology ; Female ; Genetic Variation/genetics ; Genome, Bacterial/genetics ; HIV Infections/epidemiology ; Homosexuality, Male/statistics & numerical data ; Humans ; Male ; Middle Aged ; Sexual and Gender Minorities/statistics & numerical data ; Sexually Transmitted Diseases, Bacterial/epidemiology ; Sexually Transmitted Diseases, Bacterial/microbiology ; Sexually Transmitted Diseases, Bacterial/transmission ; Shigella flexneri/genetics ; Shigella flexneri/isolation & purification ; Surveys and Questionnaires ; Whole Genome Sequencing ; Young Adult
Chemical Substances	Anti-Bacterial Agents ; Azithromycin (83905-01-5)
Language	English
Publishing date	2021-12-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2807133-5
ISSN	2165-0497 ; 2165-0497
ISSN (online)	2165-0497
ISSN	2165-0497
DOI	10.1128/Spectrum.01213-21
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Article ; Online: Modular Synthesis of Semiconducting Graft Copolymers to Achieve "Clickable" Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting.

Creamer, Adam / Fiego, Alessandra Lo / Agliano, Alice / Prados-Martin, Lino / Høgset, Håkon / Najer, Adrian / Richards, Daniel A / Wojciechowski, Jonathan P / Foote, James E J / Kim, Nayoung / Monahan, Amy / Tang, Jiaqing / Shamsabadi, André / Rochet, Léa N C / Thanasi, Ioanna A / de la Ballina, Laura R / Rapley, Charlotte L / Turnock, Stephen / Love, Elizabeth A /

Bugeon, Laurence / Dallman, Margaret J / Heeney, Martin / Kramer-Marek, Gabriela / Chudasama, Vijay / Fenaroli, Federico / Stevens, Molly M

Advanced materials (Deerfield Beach, Fla.)

2023 , Page(s) e2300413

Abstract: Semiconducting polymer nanoparticles (SPNs) are explored for applications in cancer theranostics because of their high absorption coefficients, photostability, and biocompatibility. However, SPNs are susceptible to aggregation and protein fouling in ... ...

Abstract	Semiconducting polymer nanoparticles (SPNs) are explored for applications in cancer theranostics because of their high absorption coefficients, photostability, and biocompatibility. However, SPNs are susceptible to aggregation and protein fouling in physiological conditions, which can be detrimental for in vivo applications. Here, a method for achieving colloidally stable and low-fouling SPNs is described by grafting poly(ethylene glycol) (PEG) onto the backbone of the fluorescent semiconducting polymer, poly(9,9'-dioctylfluorene-5-fluoro-2,1,3-benzothiadiazole), in a simple one-step substitution reaction, postpolymerization. Further, by utilizing azide-functionalized PEG, anti-human epidermal growth factor receptor 2 (HER2) antibodies, antibody fragments, or affibodies are site-specifically "clicked" onto the SPN surface, which allows the functionalized SPNs to specifically target HER2-positive cancer cells. In vivo, the PEGylated SPNs are found to have excellent circulation efficiencies in zebrafish embryos for up to seven days postinjection. SPNs functionalized with affibodies are then shown to be able to target HER2 expressing cancer cells in a zebrafish xenograft model. The covalent PEGylated SPN system described herein shows great potential for cancer theranostics.
Language	English
Publishing date	2023-03-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1474949-X
ISSN	1521-4095 ; 0935-9648
ISSN (online)	1521-4095
ISSN	0935-9648
DOI	10.1002/adma.202300413
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Article ; Online: An outbreak of Shiga Toxin-producing Escherichia coli O157:H7 associated with contaminated salad leaves: epidemiological, genomic and food trace back investigations - CORRIGENDUM.

Mikhail, A F W / Jenkins, C / Dallman, T J / Inns, T / Douglas, A / Martín, A I C / Fox, A / Cleary, P / Elson, R / Hawker, J

Epidemiology and infection

2018 Volume 146, Issue 14, Page(s) 1879

Language	English
Publishing date	2018-07-26
Publishing country	England
Document type	Journal Article ; Published Erratum
ZDB-ID	632982-2
ISSN	1469-4409 ; 0950-2688
ISSN (online)	1469-4409
ISSN	0950-2688
DOI	10.1017/S0950268818002108
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