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Article ; Online: Management of penetrating cardiac injuries in the Department of surgery, Mohamed Thahar Maamouri Hospital, Tunisia: report of 19 cases.

Ezzine, Sonia Baccari / Bouassida, Mahdi / Benali, Mechaal / Ghannouchi, Mosaab / Chebbi, Fethi / Sassi, Sélim / Mighri, Mohamed Mongi / Touinsi, Hassen / Sassi, Sadok

The Pan African medical journal

2012 Volume 11, Page(s) 54

Abstract: The goal of this paper is to discuss how to ameliorate the management of penetrating cardiac injuries in general surgery department. An algorithm for the initial assessment of penetrating injuries in cardiac box, based on our own experience, is presented. ...

Abstract	The goal of this paper is to discuss how to ameliorate the management of penetrating cardiac injuries in general surgery department. An algorithm for the initial assessment of penetrating injuries in cardiac box, based on our own experience, is presented. This was a retrospective study of 19 patients undergoing thoracotomy for penetrating cardiac injuries, managed in the department of general surgery of Nabeul-Tunisia, between 1994 and 2010. The mean age of patients was 25 years old. Sex ratio was 8,5. All patients had cardiac injury resulting from stab wounds inside of the pericardium. 42% of them were critically unstable, 21% had cardiac tamponnade. All these patients were quickly transferred to the operating room without any other investigations. 37% of patients were hemodynamically stable and underwent additional investigations. The management of penetrating cardiac injuries is possible in a general surgery department, but it requires a rapid prehospital transfer, a yet thorough physical examination along with efficient surgical management, all done in minimal time.
MeSH term(s)	Adult ; Cardiovascular Surgical Procedures/statistics & numerical data ; Cohort Studies ; Critical Care/statistics & numerical data ; Female ; Heart Injuries/epidemiology ; Heart Injuries/surgery ; Humans ; Length of Stay/statistics & numerical data ; Male ; Postoperative Complications/epidemiology ; Retrospective Studies ; Surgery Department, Hospital/statistics & numerical data ; Tunisia/epidemiology ; Wounds, Penetrating/epidemiology ; Wounds, Penetrating/surgery ; Wounds, Stab/epidemiology ; Wounds, Stab/surgery
Language	English
Publishing date	2012-03-22
Publishing country	Uganda
Document type	Evaluation Study ; Journal Article
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Correction to: Seroprevalence of Rift Valley Fever virus in one‑humped camels (Camelus dromedaries) in Egypt.

Marzok, Mohamed / Alkashif, Khalid / Kandeel, Mahmoud / Salem, Mohamed / Sayed-Ahmed, Mohamed Z / Selim, Abdelfattah

Tropical animal health and production

2023 Volume 55, Issue 6, Page(s) 394

Language	English
Publishing date	2023-11-04
Publishing country	United States
Document type	Published Erratum
ZDB-ID	603363-5
ISSN	1573-7438 ; 0049-4747
ISSN (online)	1573-7438
ISSN	0049-4747
DOI	10.1007/s11250-023-03806-x
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Article ; Online: Seroprevalence and associated risk factors for bovine leptospirosis in Egypt.

Selim, Abdelfattah / Marzok, Mohamed / Gattan, Hattan S / Abdelhady, Abdelhamed / Salem, Mohamed / Hereba, Abdelrahman M

Scientific reports

2024 Volume 14, Issue 1, Page(s) 4645

Abstract: Leptospirosis is caused by pathogenic bacteria of the genus Leptospira and is one of causative agents of reproductive problems leading to negative economic impact on bovine worldwide. The goal of this study was to investigate the seroprevalence of ... ...

Abstract	Leptospirosis is caused by pathogenic bacteria of the genus Leptospira and is one of causative agents of reproductive problems leading to negative economic impact on bovine worldwide. The goal of this study was to investigate the seroprevalence of Leptospira spp. in cattle in some governorates of Egypt's Nile Delta and assess the risk factors for infection. A total of 410 serum samples were collected from cattle and examined using microscopic agglutination test. The overall seroprevalence was 10.2% and the most prevalent serovars were Icterohaemorrhagiae, Pomona and Canicola. In addition, the potential risk factors were associated Leptospira spp. infection were age, herd size, history of abortion, presence of dogs and rodent control. Thus, leptospirosis is common in dairy cattle in the Nile Delta and the presence of rodents in feed and dog-accessible pastures increases the risk of Leptospira spp. infection among animals.
MeSH term(s)	Pregnancy ; Female ; Animals ; Cattle ; Dogs ; Seroepidemiologic Studies ; Egypt/epidemiology ; Cattle Diseases/epidemiology ; Cattle Diseases/microbiology ; Leptospirosis/epidemiology ; Leptospirosis/veterinary ; Leptospirosis/microbiology ; Leptospira ; Risk Factors ; Antibodies, Bacterial
Chemical Substances	Antibodies, Bacterial
Language	English
Publishing date	2024-02-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-54882-4
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Article ; Online: Prevalence and potential risk factors for Cryptosporidium spp. infection in horses from Egypt.

Alruhaili, Mohammed H / Marzok, Mohamed / Gattan, Hattan S / Salem, Mohamed / Kandeel, Mahmoud / Selim, Abdelfattah

Comparative immunology, microbiology and infectious diseases

2024 Volume 106, Page(s) 102140

Abstract: Cryptosporidium is an intestinal protozoan that cause diarrhea in livestock all over the world and have zoonotic importance. The present study aimed to determine the prevalence of Cryptosporidium spp. in horses in Egypt and evaluate the associated risk ... ...

Abstract	Cryptosporidium is an intestinal protozoan that cause diarrhea in livestock all over the world and have zoonotic importance. The present study aimed to determine the prevalence of Cryptosporidium spp. in horses in Egypt and evaluate the associated risk factors. A total of 420 fecal samples were collected from three governorates (Giza, Kafr ElSheikh and Qalyubia) and examined microscopically using Ziehl-Neelsen staining method. The overall prevalence of Cryptosporidium spp. was 29% and Kafr ElSheikh governorate had the highest rate in comparison to other areas. The prevalence of Cryptosporidium spp. in examined horses had significant association with sex, age, type of management, absence of bedding and presence of dogs. The higher prevalence rate was observed in females (32.2%), age group less than two years (43.2%), mixed (grazing and stable) horses (36.1%), animals had history of diarrhea (33%), absence of bedding (35.1%) and contact with dogs (35.7%). These findings give baseline data for further research. It is necessary to establish control strategy for Cryptosporidium spp. infection in order to lower the risk of infection in animals and human.
MeSH term(s)	Female ; Animals ; Humans ; Dogs ; Horses ; Child, Preschool ; Cryptosporidiosis/epidemiology ; Cryptosporidium ; Prevalence ; Egypt/epidemiology ; Risk Factors ; Feces ; Diarrhea/epidemiology ; Diarrhea/veterinary ; Livestock
Language	English
Publishing date	2024-02-09
Publishing country	England
Document type	Journal Article
ZDB-ID	436522-7
ISSN	1878-1667 ; 0147-9571
ISSN (online)	1878-1667
ISSN	0147-9571
DOI	10.1016/j.cimid.2024.102140
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Article ; Online: Secondary metabolites and biodiversity of actinomycetes.

Selim, Manal Selim Mohamed / Abdelhamid, Sayeda Abdelrazek / Mohamed, Sahar Saleh

Journal, genetic engineering & biotechnology

2021 Volume 19, Issue 1, Page(s) 72

Abstract: Background: The ability to produce microbial bioactive compounds makes actinobacteria one of the most explored microbes among prokaryotes. The secondary metabolites of actinobacteria are known for their role in various physiological, cellular, and ... ...

Abstract	Background: The ability to produce microbial bioactive compounds makes actinobacteria one of the most explored microbes among prokaryotes. The secondary metabolites of actinobacteria are known for their role in various physiological, cellular, and biological processes. Main body: Actinomycetes are widely distributed in natural ecosystem habitats such as soil, rhizosphere soil, actinmycorrhizal plants, hypersaline soil, limestone, freshwater, marine, sponges, volcanic cave-hot spot, desert, air, insects gut, earthworm castings, goat feces, and endophytic actinomycetes. The most important features of microbial bioactive compounds are that they have specific microbial producers: their diverse bioactivities and their unique chemical structures. Actinomycetes represent a source of biologically active secondary metabolites like antibiotics, biopesticide agents, plant growth hormones, antitumor compounds, antiviral agents, pharmacological compounds, pigments, enzymes, enzyme inhibitors, anti-inflammatory compounds, single-cell protein feed, and biosurfactant. Short conclusions: Further highlight that compounds derived from actinobacteria can be applied in a wide range of industrial applications in biomedicines and the ecological habitat is under-explored and yet to be investigated for unknown, rare actinomycetes diversity.
Language	English
Publishing date	2021-05-12
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2637420-1
ISSN	2090-5920 ; 1687-157X ; 2090-5920
ISSN (online)	2090-5920
ISSN	1687-157X ; 2090-5920
DOI	10.1186/s43141-021-00156-9
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Article ; Online: Post-COVID-19 syndrome, who at risk and why: an insight from Qatar 2022.

Adli, Nada / Bala, Mohamed / Bougmiza, Mohamed Iheb / Al-Kuwari, Mohamed Ghaith / Al-Khenji, Abdul Hameed / Selim, Nagah

Frontiers in public health

2024 Volume 12, Page(s) 1368568

Abstract: Background: Despite the recovery from the COVID-19 pandemic, many people experience post-COVID-19 syndrome, which negatively impacts their health and function. This condition has become a significant public health problem that requires immediate ... ...

Abstract	Background: Despite the recovery from the COVID-19 pandemic, many people experience post-COVID-19 syndrome, which negatively impacts their health and function. This condition has become a significant public health problem that requires immediate attention. Objective: To study the prevalence, clinical characteristics, and predictors of post-COVID-19 Syndrome in Qatar during 2022. Methods: An analytic cross-sectional study was conducted among COVID-19 confirmed cases from January 2022 to July 2022 in Qatar. A simple random sample was employed to include ( Results: Out of 368, the prevalence of post-COVID-19 syndrome was 43.2% ( Conclusion: Post-COVID-19 syndrome may go under-recognized. More efforts are needed to raise awareness and mobilize the resources to respond to this ongoing public health problem.
MeSH term(s)	Humans ; Qatar/epidemiology ; COVID-19/epidemiology ; Female ; Male ; Cross-Sectional Studies ; Adult ; Middle Aged ; Prevalence ; Post-Acute COVID-19 Syndrome ; Social Support ; Risk Factors ; SARS-CoV-2 ; Surveys and Questionnaires ; Aged
Language	English
Publishing date	2024-04-12
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2024.1368568
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Article: An unusual cause of febrile knee pain in children: Septic arthritis of the proximal tibiofibular joint (a case report).

Safouen, Ben Brahim / Mohamed, Jlidi / Ahmed, Ben Ammar / Walid, Bouaicha / Selim, Daas / Adel, Khorbi

International journal of surgery case reports

2024 Volume 119, Page(s) 109672

Abstract: Introduction and importance: Septic arthritis (SA), an infection affecting joints, is primarily attributed to bacteria, viruses, or fungi, with the hip, knee, and ankle being common sites of involvement. However, SA of the proximal tibiofibular joint is ...

Abstract	Introduction and importance: Septic arthritis (SA), an infection affecting joints, is primarily attributed to bacteria, viruses, or fungi, with the hip, knee, and ankle being common sites of involvement. However, SA of the proximal tibiofibular joint is exceptionally rare. We report a highly uncommon case of lateral knee pain with fever in an 11-year-old boy caused by SA of the proximal tibiofibular joint. Case presentation: The case involves an 11-year-old male admitted with atraumatic knee pain, fever, and limping. Physical examinations revealed no pain or tenderness of the knee joint, but a painful swelling near the proximal tibiofibular region. The patient had a temperature of 38.6 °C and a petechiae-like rash. Initial bloodwork showed an inflammatory syndrome, and blood cultures were negative. Imaging, including X-rays, ultrasound, and MRI, revealed a fusiform collection near the fibula and a 4010 mm mass. Surgery, performed through a posterolateral approach, identified purulence in the tibiofibular joint. Bacteriological samples confirmed methicillin-sensitive Staphylococcus aureus, with histopathological results confirming non-specific septic synovial involvement. The patient received a six-week course of dual empirical antibiotics and showed afebrile status postoperatively. At the two-year follow-up, the patient walked independently with no restrictions in joint mobility. Clinical discussion:* SA of the tibiofibular joint is rare but should be considered in febrile knee pain, especially if lateralized. Conclusions: A favorable outcome require a prompt diagnosis and treatment, involving surgical debridement, appropriate antibiotics, and postoperative immobilization.
Language	English
Publishing date	2024-04-20
Publishing country	Netherlands
Document type	Case Reports
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2024.109672
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Article ; Online: Thrombin activatable fibrinolysis inhibitor plasma levels and TAFI Thr325Ile genetic polymorphism in a cohort of Egyptian sickle cell disease patients and impact on disease severity.

Hamdy, Mona / Shaheen, Iman A / Khallaf, Mohamed / Selim, Yasmeen M M

Pediatric blood & cancer

2024 Volume 71, Issue 6, Page(s) e30959

Abstract: Background: Thrombin is a critical protease modulating thrombosis as well as inflammation, which are one of the main pathophysiological mechanisms in sickle vasculopathy, and its levels were reported to be high in sickle cell disease (SCD). The thrombin- ...

Abstract	Background: Thrombin is a critical protease modulating thrombosis as well as inflammation, which are one of the main pathophysiological mechanisms in sickle vasculopathy, and its levels were reported to be high in sickle cell disease (SCD). The thrombin-thrombomodulin complex activates the TAFI inhibitor of fibrinolysis, which acts by reducing plasmin affinity for its substrate thus hindering fibrinolysis. Objective: We aimed to determine the influence of the Thr325Ile single nucleotide polymorphism (SNP) on TAFI antigen levels and potential effects on the severity of SCD in a cohort of Egyptian patients. Methods: Genotyping of Thr325lle polymorphism using Taq-Man SNP genotyping assay and TAFI level measurement using an enzyme-linked immunosorbent assay were performed for 80 SCD patients (45 homozygous HbSS, 16 S/β Results: Plasma TAFI levels were higher in SCD patients with Thr325Ile polymorphism, yet the difference was not statistically significant (p = .204). SCD patients with polymorphic genotypes had a greater number of hospital admissions (p = .03). Ten patients with acute chest syndrome had the homozygous polymorphic genotype (GG), and all patients with pulmonary hypertension had the polymorphic genotype (six were homozygous [GG] and five were heterozygous [GA]). Patients with SCD complicated with pulmonary hypertension showed significantly higher plasma TAFI levels (p = .044). Conclusion: The analysis of Thr325Ile polymorphisms combined with plasma TAFI levels suggests that the analyzed SNP could influence plasma TAFL levels and SCD disease severity and hospitalization rates, which could be predictors for complex disease.
MeSH term(s)	Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Humans ; Male ; Young Adult ; Anemia, Sickle Cell/genetics ; Anemia, Sickle Cell/blood ; Carboxypeptidase B2/genetics ; Carboxypeptidase B2/blood ; Case-Control Studies ; Cohort Studies ; Egypt ; Genotype ; Polymorphism, Single Nucleotide ; Prognosis ; Severity of Illness Index
Chemical Substances	Carboxypeptidase B2 (EC 3.4.17.20) ; CPB2 protein, human (EC 3.4.17.20)
Language	English
Publishing date	2024-03-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2131448-2
ISSN	1545-5017 ; 1545-5009
ISSN (online)	1545-5017
ISSN	1545-5009
DOI	10.1002/pbc.30959
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Article: Multi-Organ Dysfunction Due to Envenoming Syndrome Following a Massive Bee Attack: A Fatal Case Study and Comprehensive Literature Review.

Osman, Ubah Mumin Ali / Turfan, Selim / Mohamud, Mohamed Farah Yusuf

International medical case reports journal

2024 Volume 17, Page(s) 353–357

Abstract: Honeybee bites are a common public health hazard, the incidence of which is gradually increasing. A bee sting incident involving more than fifty stings is categorized as massive envenomation. The clinical manifestations of honey bee stings can range from ...

Abstract	Honeybee bites are a common public health hazard, the incidence of which is gradually increasing. A bee sting incident involving more than fifty stings is categorized as massive envenomation. The clinical manifestations of honey bee stings can range from localized symptoms to severe allergic and systemic reactions.This case study presents a 60-year-old male who experienced multi-organ failure following a severe bee sting incident. According to our research, this is the first documented instance in Somalia of multi-organ failure resulting from a sting by a giant honey bee. The case highlights the potential severity of bee stings, which, while often considered minor, can lead to serious medical complications. Interestingly, despite the patient suffering numerous stings and receiving a substantial amount of venom, an immediate anaphylactic reaction did not occur. Instead, a delayed severe response leading to multi-organ failure emerged within 48 hours of the incident.
Language	English
Publishing date	2024-04-17
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2495077-4
ISSN	1179-142X
ISSN	1179-142X
DOI	10.2147/IMCRJ.S456777
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Article ; Online: Bluetongue virus infection in cattle: serosurvey and its associated risk factors.

Selim, Abdelfattah / Marzok, Mohamed / Alkashif, Khalid / Kandeel, Mahmoud / Salem, Mohamed / Sayed-Ahmed, Mohamed Z

Tropical animal health and production

2023 Volume 55, Issue 5, Page(s) 285

Abstract: Bluetongue virus (BTV) is a vector-borne virus that primarily affects sheep. However, the disease is usually asymptomatic in cattle without obvious clinical signs related to BTV infection. Although there is evidence of BTV antibodies through serology in ... ...

Abstract	Bluetongue virus (BTV) is a vector-borne virus that primarily affects sheep. However, the disease is usually asymptomatic in cattle without obvious clinical signs related to BTV infection. Although there is evidence of BTV antibodies through serology in Egypt, it is still unknown whether Egyptian cattle have ever been exposed to the virus in the north or south of the country. The study's aims were to determine the seroprevalence of BTV and evaluate the potential risk factors for BTV infection in cattle in Egypt. We used a competitive ELISA to screen 690 healthy cattle for BTV-specific immunoglobulin G (IgG) antibodies in four governorates in Egypt. A total seroprevalence of BTV antibodies in examined cattle was 51.47%, 95%CI: 48.01-55.45. The odds of BTV seropositivity were higher in Aswan (OR=1.30, 95%CI: 0.71-2.36), females (OR=3.29, 95%CI: 1.87-5.79), and elder cattle >8 years (OR=12.91, 95%CI: 6.63-25.13). Moreover, cattle contacted with other animals (OR=1.40, 95%CI: 0.94-2.10), with history of abortion (OR=4.88, 95%CI: 3.14-7.59), and those living with presence of insects (OR=12.34, 95%CI: 8-19.30) were more likely to be infected with bluetongue (BT). To effectively predict and respond to a potential BTV outbreak in Egypt, surveillance for BTV infection should be expanded to cover other susceptible ruminants and the range of the insect vectors.
MeSH term(s)	Female ; Cattle ; Animals ; Sheep ; Bluetongue virus ; Seroepidemiologic Studies ; Cattle Diseases ; Ruminants ; Bluetongue/epidemiology ; Antibodies, Viral ; Risk Factors ; Sheep Diseases
Chemical Substances	Antibodies, Viral
Language	English
Publishing date	2023-08-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	603363-5
ISSN	1573-7438 ; 0049-4747
ISSN (online)	1573-7438
ISSN	0049-4747
DOI	10.1007/s11250-023-03701-5
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