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  1. Book ; Online ; E-Book: Urine Tests

    Sharp, Victoria J.A. / Antes, Lisa M. / Sanders, M. Lee / Lockwood, Gina M.

    A Case-Based Guide to Clinical Evaluation and Application

    2020  

    Abstract: Urine tests are used by a variety of primary care providers and specialists in order to diagnose, monitor and treat patients with various medical conditions. This first-of-its-kind text is a comprehensive clinical guide to the evaluation and application ... ...

    Author's details edited by Victoria J.A. Sharp, Lisa M. Antes, M. Lee Sanders, Gina M. Lockwood
    Abstract Urine tests are used by a variety of primary care providers and specialists in order to diagnose, monitor and treat patients with various medical conditions. This first-of-its-kind text is a comprehensive clinical guide to the evaluation and application of urine tests. Clinical cases are used to highlight important aspects of urine testing. Further evaluation and management are then discussed based on the results of the urine tests. Topics covered include financial considerations, regulations, proper collection, testing methods, dipstick analysis, microscopy as well as cancer and drug screening tests, among others. Each chapter contains specific objectives for focus of study. Pertinent images, algorithms and board style review questions for important topics are also included. Written by nephrologists, urologists, other specialists and primary care physicians, Urine Tests uses a comprehensive approach to the clinical use of both common and uncommon urine testing. Primarily appealing to practicing primary care physicians, this book is also a useful resource for specialists, nurse practitioners, physician assistants, physician fellows, residents and medical students alike. .
    Keywords General practice (Medicine) ; Primary care (Medicine) ; Urology ; General Practice / Family Medicine ; Primary Care Medicine ; Urologia ; Atenció primària
    Subject code 616.07566
    Language English
    Size 1 online resource (XXI, 389 p. 77 illus., 71 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Note Includes index.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-29138-3 ; 3-030-29137-5 ; 978-3-030-29138-9 ; 978-3-030-29137-2
    DOI 10.1007/978-3-030-29138-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Advancing a More Health-Literate Approach to Patient Safety.

    Sanders, Lee M

    The Journal of pediatrics

    2019  Volume 214, Page(s) 10–11

    MeSH term(s) Comprehension ; Health Literacy ; Humans ; Parents ; Patient Discharge ; Patient Safety
    Language English
    Publishing date 2019-08-29
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2019.07.003
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  3. Article ; Online: A Synthetic Strategy toward S-, N-, and O-Heterocyclooctynes Facilitates Bioconjugation Using Multifunctional Handles.

    Hu, Yun / Spiegelhoff, Rachel / Lee, Ken S / Sanders, Kyana M / Schomaker, Jennifer M

    The Journal of organic chemistry

    2024  Volume 89, Issue 7, Page(s) 4512–4522

    Abstract: Over the past two decades, the introduction of bioorthogonal reactions has transformed the ways in which chemoselective labeling, isolation, imaging, and drug delivery are carried out in a complex biological milieu. A key feature of a good bioorthogonal ... ...

    Abstract Over the past two decades, the introduction of bioorthogonal reactions has transformed the ways in which chemoselective labeling, isolation, imaging, and drug delivery are carried out in a complex biological milieu. A key feature of a good bioorthogonal probe is the ease with which it can be attached to a target compound through bioconjugation. This paper describes the expansion of the utility of a class of unique S-, N-, and O-containing heterocyclooctynes (SNO-OCTs), which show chemoselective reactivity with type I and type II dipoles and divergent reactivities in response to electronic tuning of the alkyne. Currently, bioconjugation of SNO-OCTs to a desired target is achieved through an inconvenient aryl or amide linker at the sulfamate nitrogen. Herein, a new synthetic approach toward general SNO-OCT scaffolds is demonstrated that enables the installation of functional handles at both propargylic carbons of the heterocycloalkyne. This capability increases the utility of SNO-OCTs as labeling reagents through the design of bifunctional bioorthogonal probes with expanded capabilities. NMR kinetics also revealed up to sixfold improvement in cycloaddition rates of new analogues compared to first-generation SNO-OCTs.
    MeSH term(s) Cycloaddition Reaction ; Alkynes/chemistry ; Nitrogen/chemistry ; Indicators and Reagents ; Amides
    Chemical Substances Alkynes ; Nitrogen (N762921K75) ; Indicators and Reagents ; Amides
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c02747
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  4. Article ; Online: E-Health Care: Promise or Peril for Chronic Illness.

    Sanders, Lee M

    The Journal of pediatrics

    2018  Volume 195, Page(s) 15

    MeSH term(s) Celiac Disease ; Chronic Disease ; Delivery of Health Care ; Humans ; Telemedicine
    Language English
    Publishing date 2018-01-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2017.12.025
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  5. Article ; Online: Is COVID-19 an adverse childhood experience (ACE)

    Sanders, Lee M.

    The Journal of Pediatrics

    Implications for screening for primary care

    2020  Volume 222, Page(s) 4–6

    Keywords Pediatrics, Perinatology, and Child Health ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2020.05.064
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Stress Symptoms Among Children and Their Parents After ICU Hospitalization.

    Daughtrey, Hannah R / Lee, Justin / Boothroyd, Derek B / Burnside, Georgiana M / Shaw, Richard J / Anand, Kanwaljeet J S / Sanders, Lee M

    Journal of intensive care medicine

    2023  Volume 39, Issue 4, Page(s) 328–335

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Child ; Adolescent ; Prospective Studies ; Cross-Sectional Studies ; Parents ; Hospitalization ; Intensive Care Units, Pediatric
    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632828-3
    ISSN 1525-1489 ; 0885-0666
    ISSN (online) 1525-1489
    ISSN 0885-0666
    DOI 10.1177/08850666231201836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Telehealth Opportunities and Challenges for Managing Pediatric Obesity.

    Cueto, Victor / Sanders, Lee M

    Pediatric clinics of North America

    2020  Volume 67, Issue 4, Page(s) 647–654

    Abstract: Telehealth is well positioned to address the common challenges of providing high-quality care to children and adolescents with obesity. The potential benefits of telehealth for pediatric obesity are applicable across the full spectrum of care from ... ...

    Abstract Telehealth is well positioned to address the common challenges of providing high-quality care to children and adolescents with obesity. The potential benefits of telehealth for pediatric obesity are applicable across the full spectrum of care from diagnosis and assessment to ongoing management. This article reviews the emerging field of telehealth for the treatment of pediatric obesity. The challenges of the current approach to pediatric obesity care are explored, and the potential benefits of incorporating and implementing telehealth in this field are presented. The care of pediatric patients with obesity is particularly well suited for telehealth.
    MeSH term(s) Adolescent ; Child ; Humans ; Mobile Applications ; Observational Studies as Topic ; Pediatric Obesity/diagnosis ; Pediatric Obesity/therapy ; Quality of Health Care ; Randomized Controlled Trials as Topic ; Rural Population ; Telemedicine/methods ; Text Messaging
    Language English
    Publishing date 2020-06-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 215711-1
    ISSN 1557-8240 ; 0031-3955
    ISSN (online) 1557-8240
    ISSN 0031-3955
    DOI 10.1016/j.pcl.2020.04.007
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  8. Article ; Online: Low-voltage-activated inward current in murine antral smooth muscle cells is an artifact.

    Lee, Ji Yeon / Zheng, Haifeng / Sanders, Kenton M / Koh, Sang Don

    American journal of physiology. Cell physiology

    2021  Volume 320, Issue 6, Page(s) C966–C973

    Abstract: Two types of voltage-dependent inward currents were evoked by depolarization in murine antral smooth muscle cells (SMCs) bathed in ... ...

    Abstract Two types of voltage-dependent inward currents were evoked by depolarization in murine antral smooth muscle cells (SMCs) bathed in Ca
    MeSH term(s) Animals ; Artifacts ; Calcium/metabolism ; Calcium Channel Blockers/pharmacology ; Calcium Channels/metabolism ; Cells, Cultured ; Male ; Membrane Potentials/drug effects ; Membrane Potentials/physiology ; Mice ; Mice, Inbred C57BL ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Patch-Clamp Techniques/methods ; Potassium Channels/metabolism
    Chemical Substances Calcium Channel Blockers ; Calcium Channels ; Potassium Channels ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2021-03-31
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 392098-7
    ISSN 1522-1563 ; 0363-6143
    ISSN (online) 1522-1563
    ISSN 0363-6143
    DOI 10.1152/ajpcell.00031.2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Incidence of mental health conditions following pediatric hospital admissions: analysis of a national database.

    Daughtrey, Hannah R / Ruiz, Monica O / Felix, Nicole / Saynina, Olga / Sanders, Lee M / Anand, Kanwaljeet J S

    Frontiers in pediatrics

    2024  Volume 12, Page(s) 1344870

    Abstract: Introduction: Despite increasing survival of children following hospitalization, hospitalization may increase iatrogenic risk for mental health (MH) disorders, including acute stress, post-traumatic stress, anxiety, or depression. Using a population- ... ...

    Abstract Introduction: Despite increasing survival of children following hospitalization, hospitalization may increase iatrogenic risk for mental health (MH) disorders, including acute stress, post-traumatic stress, anxiety, or depression. Using a population-based retrospective cohort study, we assessed the rates of new MH diagnoses during the 12 months after hospitalization, including the moderating effects of ICU exposure.
    Study design/methods: This was a retrospective case control study using the Truven Health Analytics insurance database. Inclusion criteria included children aged 3-21 years, insurance enrollment for >12 months before and after hospital admission. We excluded children with hospitalization 2 years prior to index hospitalization and those with prior MH diagnoses. We extracted admission type, ICD-10 codes, demographic, clinical, and service coordination variables from the database. We established age- and sex-matched cohorts of non-hospitalized children. The primary outcome was a new MH diagnosis. Multivariable regression methods examined the risk of incident MH disorder(s) between hospitalized and non-hospitalized children. Among hospitalized children, we further assessed effect modification from ICU (vs. non-ICU) stay, admission year, length of stay, medical complexity, and geographic region.
    Results: New MH diagnoses occurred among 19,418 (7%) hospitalized children, 3,336 (8%) ICU-hospitalized children and 28,209 (5%) matched healthy controls. The most common MH diagnoses were anxiety (2.5%), depression (1.9%), and stress/trauma (2.2%) disorders. Hospitalization increased the odds of new MH diagnoses by 12.3% (OR: 1.123, 95% CI: 1.079-1.17) and ICU-hospitalization increased these odds by 63% (OR: 1.63, 95% CI: 1.483-1.79) as compared to matched, non-hospitalized children. Children with non-complex chronic diseases (OR: 2.91, 95% CI: 2.84-2.977) and complex chronic diseases (OR: 5.16, 95% CI: 5.032-5.289) had a substantially higher risk for new MH diagnoses after hospitalization compared to patients with acute illnesses.
    Conclusion: Pediatric hospitalization is associated with higher, long-term risk of new mental health diagnoses, and ICU hospitalization further increases that risk within 12 months of the acute episode. Acute care hospitalization confers iatrogenic risks that warrant long-term mental and behavioral health follow-up.
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2024.1344870
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Advancing Adolescent and Young Adult HIV Prevention and Care and Treatment Through Use of Multi-level Theories and Frameworks: A Scoping Review and Adapted HIV Ecological Framework.

    Denison, Julie A / Willis, Kalai / DeLong, Stephanie M / Sievwright, Kirsty M / Agwu, Allison L / Arrington-Sanders, Renata / Kaufman, Michelle R / Prabhu, Sandeep / Williams, Ashlie M / Fields, Errol L / Alexander, Kamila A / Lee, Lana / Yang, Cui

    AIDS and behavior

    2024  Volume 28, Issue 5, Page(s) 1694–1707

    Abstract: While multi-level theories and frameworks have become a cornerstone in broader efforts to address HIV inequities, little is known regarding their application in adolescent and young adult (AYA) HIV research. To address this gap, we conducted a scoping ... ...

    Abstract While multi-level theories and frameworks have become a cornerstone in broader efforts to address HIV inequities, little is known regarding their application in adolescent and young adult (AYA) HIV research. To address this gap, we conducted a scoping review to assess the use and application of multi-level theories and frameworks in AYA HIV prevention and care and treatment empirical research. We systematically searched five databases for articles published between 2010 and May 2020, screened abstracts, and reviewed eligible full-text articles for inclusion. Of the 5890 citations identified, 1706 underwent full-text review and 88 met the inclusion criteria: 70 focused on HIV prevention, with only 14 on care and treatment, 2 on both HIV prevention and care and treatment, and 2 on HIV-affected AYA. Most authors described the theory-based multi-level framework as informing their data analysis, with only 12 describing it as informing/guiding an intervention. More than seventy different multi-level theories were described, with 38% utilizing socio-ecological models or the eco-developmental theory. Findings were used to inform the adaptation of an AYA World Health Organization multi-level framework specifically to guide AYA HIV research.
    MeSH term(s) Humans ; HIV Infections/prevention & control ; Adolescent ; Young Adult ; Male ; Female
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 1339885-4
    ISSN 1573-3254 ; 1090-7165
    ISSN (online) 1573-3254
    ISSN 1090-7165
    DOI 10.1007/s10461-023-04255-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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