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  1. Article: Lung Ultrasound: A Leading Diagnostic Tool.

    Demi, Marcello / Soldati, Gino

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 10

    Abstract: Thoracic ultrasound is an important diagnostic tool employed by many clinicians in well-defined applications [ ... ]. ...

    Abstract Thoracic ultrasound is an important diagnostic tool employed by many clinicians in well-defined applications [...].
    Language English
    Publishing date 2023-05-12
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13101710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: What Is COVID 19 Teaching Us about Pulmonary Ultrasound?

    Soldati, Gino / Demi, Marcello

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 4

    Abstract: In lung ultrasound (LUS), the interactions between the acoustic pulse and the lung surface (including the pleura and a small subpleural layer of tissue) are crucial. Variations of the peripheral lung density and the subpleural alveolar shape and its ... ...

    Abstract In lung ultrasound (LUS), the interactions between the acoustic pulse and the lung surface (including the pleura and a small subpleural layer of tissue) are crucial. Variations of the peripheral lung density and the subpleural alveolar shape and its configuration are typically connected to the presence of ultrasound artifacts and consolidations. COVID-19 pneumonia can give rise to a variety of pathological pulmonary changes ranging from mild diffuse alveolar damage (DAD) to severe acute respiratory distress syndrome (ARDS), characterized by peripheral bilateral patchy lung involvement. These findings are well described in CT imaging and in anatomopathological cases. Ultrasound artifacts and consolidations are therefore expected signs in COVID-19 pneumonia because edema, DAD, lung hemorrhage, interstitial thickening, hyaline membranes, and infiltrative lung diseases when they arise in a subpleural position, generate ultrasound findings. This review analyzes the structure of the ultrasound images in the normal and pathological lung given our current knowledge, and the role of LUS in the diagnosis and monitoring of patients with COVID-19 lung involvement.
    Language English
    Publishing date 2022-03-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12040838
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Lung Ultrasound Artifacts Interpreted as Pathology Footprints.

    Demi, Marcello / Soldati, Gino / Ramalli, Alessandro

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 6

    Abstract: Background: The original observation that lung ultrasound provides information regarding the physical state of the organ, rather than the anatomical details related to the disease, has reinforced the idea that the observed acoustic signs represent ... ...

    Abstract Background: The original observation that lung ultrasound provides information regarding the physical state of the organ, rather than the anatomical details related to the disease, has reinforced the idea that the observed acoustic signs represent artifacts. However, the definition of artifact does not appear adequate since pulmonary ultrasound signs have shown valuable diagnostic accuracy, which has been usefully exploited by physicians in numerous pathologies.
    Method: A specific method has been used over the years to analyze lung ultrasound data and to convert artefactual information into anatomical information.
    Results: A physical explanation of the genesis of the acoustic signs is provided, and the relationship between their visual characteristics and the surface histopathology of the lung is illustrated. Two important sources of potential signal alteration are also highlighted.
    Conclusions: The acoustic signs are generated by acoustic traps that progressively release previously trapped energy. Consequently, the acoustic signs highlight the presence of acoustic traps and quantitatively describe their distribution on the lung surface; they are not artifacts, but pathology footprints and anatomical information. Moreover, the impact of the dynamic focusing algorithms and the impact of different probes on the visual aspect of the acoustic signs should not be neglected.
    Language English
    Publishing date 2023-03-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13061139
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  4. Article ; Online: Trick or Trap? Reply to Vertical Artifacts as Lung Ultrasound Signs.

    Smargiassi, Andrea / Zanforlin, Alessandro / Tursi, Francesco / Soldati, Gino / Inchingolo, Riccardo

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2023  Volume 43, Issue 1, Page(s) 215–216

    MeSH term(s) Humans ; Artifacts ; Lung/diagnostic imaging ; Ultrasonography
    Language English
    Publishing date 2023-09-21
    Publishing country England
    Document type Letter
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.16337
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  5. Article ; Online: What Is COVID 19 Teaching Us about Pulmonary Ultrasound?

    Gino Soldati / Marcello Demi

    Diagnostics, Vol 12, Iss 838, p

    2022  Volume 838

    Abstract: In lung ultrasound (LUS), the interactions between the acoustic pulse and the lung surface (including the pleura and a small subpleural layer of tissue) are crucial. Variations of the peripheral lung density and the subpleural alveolar shape and its ... ...

    Abstract In lung ultrasound (LUS), the interactions between the acoustic pulse and the lung surface (including the pleura and a small subpleural layer of tissue) are crucial. Variations of the peripheral lung density and the subpleural alveolar shape and its configuration are typically connected to the presence of ultrasound artifacts and consolidations. COVID-19 pneumonia can give rise to a variety of pathological pulmonary changes ranging from mild diffuse alveolar damage (DAD) to severe acute respiratory distress syndrome (ARDS), characterized by peripheral bilateral patchy lung involvement. These findings are well described in CT imaging and in anatomopathological cases. Ultrasound artifacts and consolidations are therefore expected signs in COVID-19 pneumonia because edema, DAD, lung hemorrhage, interstitial thickening, hyaline membranes, and infiltrative lung diseases when they arise in a subpleural position, generate ultrasound findings. This review analyzes the structure of the ultrasound images in the normal and pathological lung given our current knowledge, and the role of LUS in the diagnosis and monitoring of patients with COVID-19 lung involvement.
    Keywords COVID-19 ; clinical review ; lung ultrasound imaging ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Short-coupled Purkinje ectopy inducible by pharmacological and hyperventilation tests.

    Grifoni, Gino / Haissaguerre, Michel / Bongiorni, Maria Grazia / Benali, Karim / Soldati, Ezio / Zucchelli, Giulio

    HeartRhythm case reports

    2023  Volume 10, Issue 1, Page(s) 68–71

    Language English
    Publishing date 2023-10-31
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2023.10.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Lung Ultrasound Artifacts Interpreted as Pathology Footprints

    Marcello Demi / Gino Soldati / Alessandro Ramalli

    Diagnostics, Vol 13, Iss 1139, p

    2023  Volume 1139

    Abstract: Background: The original observation that lung ultrasound provides information regarding the physical state of the organ, rather than the anatomical details related to the disease, has reinforced the idea that the observed acoustic signs represent ... ...

    Abstract Background: The original observation that lung ultrasound provides information regarding the physical state of the organ, rather than the anatomical details related to the disease, has reinforced the idea that the observed acoustic signs represent artifacts. However, the definition of artifact does not appear adequate since pulmonary ultrasound signs have shown valuable diagnostic accuracy, which has been usefully exploited by physicians in numerous pathologies. Method: A specific method has been used over the years to analyze lung ultrasound data and to convert artefactual information into anatomical information. Results: A physical explanation of the genesis of the acoustic signs is provided, and the relationship between their visual characteristics and the surface histopathology of the lung is illustrated. Two important sources of potential signal alteration are also highlighted. Conclusions: The acoustic signs are generated by acoustic traps that progressively release previously trapped energy. Consequently, the acoustic signs highlight the presence of acoustic traps and quantitatively describe their distribution on the lung surface; they are not artifacts, but pathology footprints and anatomical information. Moreover, the impact of the dynamic focusing algorithms and the impact of different probes on the visual aspect of the acoustic signs should not be neglected.
    Keywords lung ultrasound ; b-lines ; vertical artifacts ; pulmonary artifacts ; physical models ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Vertical Artifacts in Lung Ultrasonography: Some Common Clinician Questions and the Related Engineer Answers.

    Demi, Marcello / Buda, Natalia / Soldati, Gino

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 1

    Abstract: Introduction: Vertical artifacts, including B lines, are frequently seen in a variety of lung diseases. Their sonomorphology varies in length, width, shape, and internal reverberations. The reason for this diversity is still unknown and is the cause of ... ...

    Abstract Introduction: Vertical artifacts, including B lines, are frequently seen in a variety of lung diseases. Their sonomorphology varies in length, width, shape, and internal reverberations. The reason for this diversity is still unknown and is the cause of discussion between clinicians and ultrasound physics engineers.
    Aim: The aim of this work is to sum up the most common clinician observations and provide an explanation to each of them derived from ultrasound physics.
    Materials and methods: Based on clinical and engineering experiences as well as data collected from relevant literature, the sonomorphology of vertical artifacts was analyzed. Thirteen questions and answers were prepared on the common sonomorphology of vertical artifacts, current nomenclature, and clinical observations.
    Conclusions: From a clinical standpoint, the analysis of vertical artifacts is very important and requires that further clinical studies be conducted in cooperation with engineers who specialize in physics.
    Language English
    Publishing date 2022-01-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12010215
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  9. Article ; Online: Vertical Artifacts in Lung Ultrasonography

    Marcello Demi / Natalia Buda / Gino Soldati

    Diagnostics, Vol 12, Iss 215, p

    Some Common Clinician Questions and the Related Engineer Answers

    2022  Volume 215

    Abstract: Introduction: Vertical artifacts, including B lines, are frequently seen in a variety of lung diseases. Their sonomorphology varies in length, width, shape, and internal reverberations. The reason for this diversity is still unknown and is the cause of ... ...

    Abstract Introduction: Vertical artifacts, including B lines, are frequently seen in a variety of lung diseases. Their sonomorphology varies in length, width, shape, and internal reverberations. The reason for this diversity is still unknown and is the cause of discussion between clinicians and ultrasound physics engineers. Aim: The aim of this work is to sum up the most common clinician observations and provide an explanation to each of them derived from ultrasound physics. Materials and Methods: Based on clinical and engineering experiences as well as data collected from relevant literature, the sonomorphology of vertical artifacts was analyzed. Thirteen questions and answers were prepared on the common sonomorphology of vertical artifacts, current nomenclature, and clinical observations. Conclusions: From a clinical standpoint, the analysis of vertical artifacts is very important and requires that further clinical studies be conducted in cooperation with engineers who specialize in physics.
    Keywords lung ultrasonography LUS ; B lines ; vertical artifacts ; sonomorphology of artifacts ; cardiac edema ; pulmonary fibrosis ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Ultrasound patterns of pulmonary edema.

    Soldati, Gino / Demi, Marcello / Demi, Libertario

    Annals of translational medicine

    2019  Volume 7, Issue Suppl 1, Page(s) S16

    Language English
    Publishing date 2019-04-11
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2019.01.49
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