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  1. Article ; Online: Correction: La Sala et al. New Fast Acting Glucagon for Recovery from Hypoglycemia, a Life-Threatening Situation: Nasal Powder and Injected Stable Solutions.

    La Sala, Lucia / Pontiroli, Antonio E

    International journal of molecular sciences

    2023  Volume 24, Issue 6

    Abstract: The authors would like to make corrections to the reference citations in the original article [ ... ]. ...

    Abstract The authors would like to make corrections to the reference citations in the original article [...].
    Language English
    Publishing date 2023-03-15
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24065625
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  2. Article ; Online: Letter to the Editor: Intranasal Glucagon for Hypoglycemia.

    Pontiroli, Antonio E

    Current diabetes reports

    2017  Volume 17, Issue 1, Page(s) 1

    Language English
    Publishing date 2017-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 2065167-3
    ISSN 1539-0829 ; 1534-4827
    ISSN (online) 1539-0829
    ISSN 1534-4827
    DOI 10.1007/s11892-017-0833-z
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  3. Article ; Online: Role of obesity and hypertension in the incidence of atrial fibrillation, ischaemic heart disease and heart failure in patients with diabetes.

    Sala, Lucia La / Pontiroli, Antonio E

    Cardiovascular diabetology

    2021  Volume 20, Issue 1, Page(s) 162

    Abstract: In a cohort study performed using primary care databases in a General Practitioners Network, Groenewegen et al. report a clear association between diabetes and incidence of the major chronic progressive heart diseases, notably heart failure (Groenewegen ... ...

    Abstract In a cohort study performed using primary care databases in a General Practitioners Network, Groenewegen et al. report a clear association between diabetes and incidence of the major chronic progressive heart diseases, notably heart failure (Groenewegen et al. in Cardiovasc Diabetol 20:123, 2021). However, no mention is made of body mass index and hypertension in the methods or in the results. Obesity is linked to hypertension and hypertension is a major risk factor for all cardiovascular diseases, and prospective studies have shown that obesity and hypertension contribute significantly to atrial fibrillation in persons with diabetes. The data would be improved by assessing the role of obesity and of hypertension in the incidence of heart diseases in these patients. This would also lead to a better and personalized treatment of patients with diabetes, for instance through weight loss and intensification of treatment of hypertension, to modify the incidence of atrial fibrillation, ischaemic heart disease and heart failure.
    MeSH term(s) Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Cohort Studies ; Diabetes Mellitus/diagnosis ; Diabetes Mellitus/epidemiology ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Humans ; Hypertension/diagnosis ; Hypertension/epidemiology ; Incidence ; Myocardial Ischemia/diagnosis ; Myocardial Ischemia/epidemiology ; Obesity/diagnosis ; Obesity/epidemiology ; Prospective Studies ; Risk Factors
    Language English
    Publishing date 2021-08-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ISSN 1475-2840
    ISSN (online) 1475-2840
    DOI 10.1186/s12933-021-01331-5
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  4. Article ; Online: Correction

    Lucia La Sala / Antonio E. Pontiroli

    International Journal of Molecular Sciences, Vol 24, Iss 5625, p

    La Sala et al. New Fast Acting Glucagon for Recovery from Hypoglycemia, a Life-Threatening Situation: Nasal Powder and Injected Stable Solutions. Int. J. Mol. Sci. 2021, 22, 10643

    2023  Volume 5625

    Abstract: The authors would like to make corrections to the reference citations in the original article [.] ...

    Abstract The authors would like to make corrections to the reference citations in the original article [.]
    Keywords n/a ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Comment on: Risk of non-hormonal cancer after bariatric surgery: meta-analysis of retrospective observational studies.

    Pontiroli, Antonio E / Ceriani, Valerio / Tagliabue, Marta / Centofanti, Lucia / Tagliabue, Elena

    The British journal of surgery

    2023  Volume 110, Issue 5, Page(s) 618

    MeSH term(s) Humans ; Retrospective Studies ; Bariatric Surgery ; Neoplasms ; Observational Studies as Topic
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Meta-Analysis ; Letter ; Comment
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znad068
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    Uk I Zs.66: Show issues Location:
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  6. Article ; Online: Intranasal versus injectable glucagon for hypoglycemia in type 1 diabetes: systematic review and meta-analysis.

    Pontiroli, Antonio E / Tagliabue, Elena

    Acta diabetologica

    2020  Volume 57, Issue 6, Page(s) 743–749

    Abstract: Aims: Glucagon is used to resolve severe hypoglycemia in unconscious patients with diabetes, requiring third-party assistance. A few studies have shown that intranasal (IN) glucagon causes resolution of hypoglycemia in insulin-treated patients with type ...

    Abstract Aims: Glucagon is used to resolve severe hypoglycemia in unconscious patients with diabetes, requiring third-party assistance. A few studies have shown that intranasal (IN) glucagon causes resolution of hypoglycemia in insulin-treated patients with type 1 (T1DM) diabetes. This systematic review and meta-analysis updates the comparison of the effectiveness of IN glucagon with injected intramuscular/subcutaneous (IM/SC) glucagon in treatment of hypoglycemia in T1DM.
    Methods: Controlled randomized studies were considered; eight studies, published in English, were included in a meta-analysis (random-effects model). Intervention effect (resolution of hypoglycemia) was expressed as odds ratio (OR), with 95% confidence intervals. Meta-regression was employed to correlate the effect with size of studies, age of patients, basal blood glucose levels.
    Results: In a total of 467 treatments in 269 patients with IN and IM/SC glucagon, the OR IN versus IM/SC was 0.61 (CI 0.13-2.82); since four of eight studies showed 100% effectiveness, a simulation was made with 1 failure for each treatment; in this simulation analysis, the OR was 0.80 (95% CI 0.28-2.32). Heterogeneity was low and not statistically significant. Publication bias was absent, and quality of papers was high. At meta-regression, no correlation was found between the effect and number of patients in each study, age of patients, basal blood glucose levels. No study formally compared IN versus IM/SC in unconscious patients.
    Conclusions: This meta-analysis indicates that in conscious T1DM patients IN glucagon and IM/SC glucagon are equally effective in resolution of hypoglycemia.
    MeSH term(s) Administration, Intranasal ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/epidemiology ; Glucagon/administration & dosage ; Glucagon/adverse effects ; Humans ; Hypoglycemia/chemically induced ; Hypoglycemia/drug therapy ; Hypoglycemia/epidemiology ; Injections, Intramuscular ; Injections, Subcutaneous ; Insulin/administration & dosage ; Insulin/adverse effects ; Randomized Controlled Trials as Topic/statistics & numerical data ; Treatment Outcome
    Chemical Substances Blood Glucose ; Insulin ; Glucagon (9007-92-5)
    Language English
    Publishing date 2020-02-06
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 1097676-0
    ISSN 1432-5233 ; 0940-5429
    ISSN (online) 1432-5233
    ISSN 0940-5429
    DOI 10.1007/s00592-020-01483-y
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    Zs.A 611: Show issues Location:
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  7. Article ; Online: Effect of Prolonged and Substantial Weight Loss on Incident Atrial Fibrillation: A Systematic Review and Meta-Analysis.

    Pontiroli, Antonio E / Centofanti, Lucia / Le Roux, Carel W / Magnani, Silvia / Tagliabue, Elena / Folli, Franco

    Nutrients

    2023  Volume 15, Issue 4

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Humans ; Atrial Fibrillation/complications ; Obesity ; Weight Loss ; Bariatric Surgery/methods ; Overweight/complications
    Language English
    Publishing date 2023-02-14
    Publishing country Switzerland
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15040940
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  8. Article ; Online: Life Expectancy after Bariatric Surgery - the Swedish Obese Subjects Study.

    Tagliabue, Elena / Ceriani, Valerio / Pontiroli, Antonio E

    The New England journal of medicine

    2021  Volume 384, Issue 1, Page(s) 88

    MeSH term(s) Bariatric Surgery ; Humans ; Life Expectancy ; Obesity ; Sweden/epidemiology
    Language English
    Publishing date 2021-01-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2033331
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    Ua VI Zs.34: Show issues Location:
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  9. Article ; Online: Vaccination against influenza viruses reduces infection, not hospitalization or death, from respiratory COVID-19: A systematic review and meta-analysis.

    Pontiroli, Antonio E / Scovenna, Francesco / Carlini, Valentina / Tagliabue, Elena / Martin-Delgado, Jimmy / La Sala, Lucia / Tanzi, Elisabetta / Zanoni, Ivan

    Journal of medical virology

    2024  Volume 96, Issue 1, Page(s) e29343

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19 and has brought a huge burden in terms of human lives. Strict social distance and influenza vaccination have been recommended to avoid co-infections between influenza viruses ... ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19 and has brought a huge burden in terms of human lives. Strict social distance and influenza vaccination have been recommended to avoid co-infections between influenza viruses and SARS-CoV-2. Scattered reports suggested a protective effect of influenza vaccine on COVID-19 development and severity. We analyzed 51 studies on the capacity of influenza vaccination to affect infection with SARS-CoV-2, hospitalization, admission to Intensive Care Units (ICU), and mortality. All subjects taken into consideration did not receive any anti-SARS-CoV-2 vaccine, although their status with respect to previous infections with SARS-CoV-2 is not known. Comparison between vaccinated and not-vaccinated subjects for each of the four endpoints was expressed as odds ratio (OR), with 95% confidence intervals (CIs); all analyses were performed by DerSimonian and Laird model, and Hartung-Knapp model when studies were less than 10. In a total of 61 029 936 subjects from 33 studies, influenza vaccination reduced frequency of SARS-CoV-2 infection [OR plus 95% CI = 0.70 (0.65-0.77)]. The effect was significant in all studies together, in health care workers and in the general population; distance from influenza vaccination and the type of vaccine were also of importance. In 98 174 subjects from 11 studies, frequency of ICU admission was reduced with influenza vaccination [OR (95% CI) = 0.71 (0.54-0.94)]; the effect was significant in all studies together, in pregnant women and in hospitalized subjects. In contrast, in 4 737 328 subjects from 14 studies hospitalization was not modified [OR (95% CI) = 1.05 (0.82-1.35)], and in 4 139 660 subjects from 19 studies, mortality was not modified [OR (95% CI) = 0.76 (0.26-2.20)]. Our study emphasizes the importance of influenza vaccination in the protection against SARS-CoV-2 infection.
    MeSH term(s) Female ; Humans ; Pregnancy ; COVID-19/epidemiology ; COVID-19/mortality ; Hospitalization ; Influenza Vaccines/administration & dosage ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; SARS-CoV-2 ; Vaccination
    Chemical Substances Influenza Vaccines
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29343
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  10. Article ; Online: Coffee, LDL-cholesterol and cardiovascular risk.

    La Sala, Lucia / Pontiroli, Antonio E

    Nutrition, metabolism, and cardiovascular diseases : NMCD

    2021  Volume 31, Issue 9, Page(s) 2735–2736

    MeSH term(s) Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Cholesterol, LDL ; Coffee/adverse effects ; Heart Disease Risk Factors ; Humans ; Risk Factors
    Chemical Substances Cholesterol, LDL ; Coffee
    Language English
    Publishing date 2021-06-22
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1067704-5
    ISSN 1590-3729 ; 0939-4753
    ISSN (online) 1590-3729
    ISSN 0939-4753
    DOI 10.1016/j.numecd.2021.05.036
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