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Book ; Online: Chapter Solution-Processed Graphene-Based Transparent Conductive Electrodes as Ideal ITO Alternatives for Organic Solar Cells

Stylianakis, Minas M. / Konios, Dimitrios / Petridis, Konstantinos / Kymakis, Emmanuel

2017

Keywords	Solid state chemistry ; organic solar cells, transparent electrodes, graphene, reduction
Size	1 Online-Ressource
Publisher	InTechOpen
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021051201
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: A digital twin ecosystem for additive manufacturing using a real-time development platform.

Pantelidakis, Minas / Mykoniatis, Konstantinos / Liu, Jia / Harris, Gregory

The International journal, advanced manufacturing technology

2022 Volume 120, Issue 9-10, Page(s) 6547–6563

Abstract: Additive manufacturing is often used in rapid prototyping and manufacturing, allowing the creation of lighter, more complex designs that are difficult or too expensive to build using traditional manufacturing methods. This work considers the ... ...

Abstract	Additive manufacturing is often used in rapid prototyping and manufacturing, allowing the creation of lighter, more complex designs that are difficult or too expensive to build using traditional manufacturing methods. This work considers the implementation of a novel digital twin ecosystem that can be used for testing, process monitoring, and remote management of an additive manufacturing-fused deposition modeling machine in a simulated virtual environment. The digital twin ecosystem is comprised of two approaches. One approach is data-driven by an open-source 3D printer web controller application that is used to capture its status and key parameters. The other approach is data-driven by externally mounted sensors to approximate the actual behavior of the 3D printer and achieve accurate synchronization between the physical and virtual 3D printers. We evaluate the sensor-data-driven approach against the web controller approach, which is considered to be the ground truth. We achieve near-real-time synchronization between the physical machine and its digital counterpart and have validated the digital twin in terms of position, temperature, and run duration. Our digital twin ecosystem is cost-efficient, reliable, replicable, and hence can be utilized to provide legacy equipment with digital twin capabilities, collect historical data, and generate analytics.
Language	English
Publishing date	2022-04-13
Publishing country	England
Document type	Journal Article
ZDB-ID	1476510-X
ISSN	1433-3015 ; 0268-3768
ISSN (online)	1433-3015
ISSN	0268-3768
DOI	10.1007/s00170-022-09164-6
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Article ; Online: HPV16

Konstantopoulos, Georgios / Leventakou, Danai / Saltiel, Despoina-Rozi / Zervoudi, Efthalia / Logotheti, Eirini / Pettas, Spyros / Karagianni, Korina / Daiou, Angeliki / Hatzistergos, Konstantinos E / Dafou, Dimitra / Arsenakis, Minas / Kottaridi, Christine

Viruses

2024 Volume 16, Issue 1

Abstract: Human Papillomaviruses have been associated with the occurrence of cervical cancer, the fourth most common cancer that affects women globally, while 70% of cases are caused by infection with the high-risk types HPV16 and HPV18. The integration of these ... ...

Abstract	Human Papillomaviruses have been associated with the occurrence of cervical cancer, the fourth most common cancer that affects women globally, while 70% of cases are caused by infection with the high-risk types HPV16 and HPV18. The integration of these viruses' oncogenes
MeSH term(s)	Female ; Humans ; B7-H1 Antigen/genetics ; Human papillomavirus 16/genetics ; Immune Evasion ; MicroRNAs/genetics ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/virology ; Oncogene Proteins, Viral/genetics
Chemical Substances	B7-H1 Antigen ; MicroRNAs ; MIRN143 microRNA, human ; E6 protein, Human papillomavirus type 16 ; Oncogene Proteins, Viral ; HIF1A protein, human
Language	English
Publishing date	2024-01-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v16010113
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Article: Medical Liability in Obstetrics/Gynecology and Co-liability With Anesthesiology in Greece: A Retrospective Study.

Samara, Evangelia / Tzoumas, Lambros / Tzoumas, Konstantinos / Paschopoulos, Minas / Tzimas, Petros / Papadopoulos, Georgios

Cureus

2022 Volume 14, Issue 10, Page(s) e30931

Abstract: Objective To evaluate the current landscape regarding medical liability in obstetric-gynecology (OB/GYN) physicians in Greece. Materials and methods Published court decisions of criminal, civil, administrative, and disciplinary content were searched in ... ...

Abstract	Objective To evaluate the current landscape regarding medical liability in obstetric-gynecology (OB/GYN) physicians in Greece. Materials and methods Published court decisions of criminal, civil, administrative, and disciplinary content were searched in legal information banks for the years 1988-2021. The causes that led to the adverse outcome and the decisions were analyzed. Results A total of 184 decisions were directed against OB/GYNs. One hundred seventeen records concerned criminal cases and 67 civil cases. Thirty-four decisions concerned criminal cases of negligent homicide, 35 criminal cases of bodily harm, and 19 were acquittals. The most common causes of bodily injuries were neonatal encephalopathy, obstetric paralysis - quadriplegia and brachial plexus paralysis, and obstetric bleeding. Conclusion According to our results, there is a great need and challenge to maintain high standards in daily practice with continuous training and the use of international protocols. Furthermore, for each case, continuous monitoring of parturients and newborns and coordinated cooperation are necessary to reduce mortality and morbidity.
Language	English
Publishing date	2022-10-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.30931
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Article: Potential Ophthalmological Side Effects Induced by Anti-Neoplastic Regimens for the Treatment of Genitourinary Cancers: A Review.

Sakellakis, Minas / Spathas, Nikolaos / Tsaousis, Konstantinos T / Nikitiadis, Emmanouil N / Linardou, Helena / Diakonis, Vasilios F

Cureus

2022 Volume 14, Issue 7, Page(s) e27266

Abstract: The outcomes of patients with genitourinary (GU) cancers have been steadily improving in recent years. Novel therapies have entered our armamentarium, while several other regimens are currently being studied in clinical trials. This recent explosion of ... ...

Abstract	The outcomes of patients with genitourinary (GU) cancers have been steadily improving in recent years. Novel therapies have entered our armamentarium, while several other regimens are currently being studied in clinical trials. This recent explosion of new agents has improved patient survival and the quality of life for patients, but has also significantly increased the frequency of several side effects. The current review will focus on the potential ocular adverse reactions of GU neoplastic treatments. The broad spectrum of manifestations of ocular toxicity underscores the uniqueness and complexity of the anatomic, physiologic, and metabolic features of the human eye. Most side effects are mild in severity and transient, but some can be severe, disabling, and irreversible. Clinicians should be aware of complications that might be vision threatening and impact the patient's quality of life. In this review, we focused on the ocular toxicity of the antineoplastic regimens that are currently used for the treatment of GU, including prostate cancer, bladder cancer, renal cell carcinoma, testicular cancer, pheochromocytoma, adrenocortical carcinoma, and penile cancer.
Language	English
Publishing date	2022-07-26
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.27266
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Article ; Online: 'My new home?': Strategies and challenges of refugee integration programs in Portugal.

Constantino, Catarina / Minas, Maria

Journal of community psychology

2022 Volume 50, Issue 8, Page(s) 3792–3808

Abstract: Europe is experiencing the greatest humanitarian crisis since the Second World War, which is reflected in an unprecedented influx of refugees into Europe. Against this backdrop, the effective strategies and challenges faced by the programs designed to ... ...

Abstract	Europe is experiencing the greatest humanitarian crisis since the Second World War, which is reflected in an unprecedented influx of refugees into Europe. Against this backdrop, the effective strategies and challenges faced by the programs designed to facilitate the integration of refugees need to be understood. Portugal, together with other countries, has opened its doors to refugees. In this study, qualitative methods are used to understand how the refugee reception and integration are being conducted in Portugal. The perspectives of both refugees and professionals involved in programs aimed at promoting the integration of refugees are taken into consideration. The results suggest that, despite the existence of best practices in the various types of programs, there is significant room for improvement. Thus, specific changes to these programs are proposed with a view to boosting their efficacy and facilitating the integration of refugees in Portugal.
MeSH term(s)	Humans ; Portugal ; Refugees
Language	English
Publishing date	2022-05-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491194-2
ISSN	1520-6629 ; 0090-4392
ISSN (online)	1520-6629
ISSN	0090-4392
DOI	10.1002/jcop.22873
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Article ; Online: Impact of personality on the decision process and on satisfaction rates in pseudophakic presbyopic correction.

Ntonti, Panagiota / Bakirtzis, Minas / Delibasis, Konstantinos / Seimenis, Ioannis / Tsinopoulos, Ioannis / Labiris, Georgios

Journal of cataract and refractive surgery

2022 Volume 48, Issue 12, Page(s) 1433–1439

Abstract: Purpose: To explore the impact of personality on the decision process and satisfaction rates in pseudophakic presbyopic correction.: Setting: Department of Ophthalmology, University Hospital of Alexandroupolis, Greece.: Design: Prospective, ... ...

Abstract	Purpose: To explore the impact of personality on the decision process and satisfaction rates in pseudophakic presbyopic correction. Setting: Department of Ophthalmology, University Hospital of Alexandroupolis, Greece. Design: Prospective, comparative study. Methods: A consistent consultation was conducted in patients with cataract that explained the benefits and the drawbacks of bilateral trifocal correction, which was offered at no extra cost. In all participants, personality was evaluated by The Traits Personality Questionnaire 5. Data modeling with decision trees and multiple regression analysis identified the contributions of personality traits to the decision process and postoperative satisfaction. Results: Of 120 participants (60 men and 60 women), 81 (67.5%, 24 men, 57 women) selected premium correction. In men, low neuroticism and high extraversion were the primary personality contributors for selecting premium surgery. In women, all personality traits contributed to the selection process. Women were more demanding in the expected postoperative distant acuity than men (0.1 vs 0.2 logMAR) to present high satisfaction. For both men and women, openness to experience, conscientiousness, and extraversion are primary contributors for optimal satisfaction rates. Conclusions: Men and women demonstrate differences in the selection process for premium pseudophakic surgery and differences in the expected postoperative visual acuity. It seems that the personality of the patient plays a significant role in the perceived outcome after premium surgery.
MeSH term(s)	Male ; Humans ; Female ; Personal Satisfaction ; Prospective Studies ; Personality ; Surveys and Questionnaires ; Cataract
Language	English
Publishing date	2022-07-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	632744-8
ISSN	1873-4502 ; 0886-3350
ISSN (online)	1873-4502
ISSN	0886-3350
DOI	10.1097/j.jcrs.0000000000001021
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Article ; Online: Photo-Fenton and TiO

Kanata, Eirini / Paspaltsis, Ioannis / Sotiriadis, Sotiris / Berberidou, Chrysanthi / Tsoumachidou, Sophia / Dafou, Dimitra / Xanthopoulos, Konstantinos / Arsenakis, Minas / Arsenakis, Athanasios / Poulios, Ioannis / Sklaviadis, Theodoros

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 3

Abstract: Photocatalytic inactivation of pathogens in aqueous waste is gaining increasing attention. Several homogeneous and heterogeneous photocatalytic protocols exist using the Fenton's reagent and ... ...

Abstract	Photocatalytic inactivation of pathogens in aqueous waste is gaining increasing attention. Several homogeneous and heterogeneous photocatalytic protocols exist using the Fenton's reagent and TiO
MeSH term(s)	Hydrogen Peroxide ; Titanium/pharmacology ; Catalysis
Chemical Substances	titanium dioxide (15FIX9V2JP) ; Hydrogen Peroxide (BBX060AN9V) ; Titanium (D1JT611TNE)
Language	English
Publishing date	2023-01-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28031199
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Article ; Online: Development and Validation of the First Smart TV-Based Visual Acuity Test

Georgios Labiris / Konstantinos Delibasis / Eirini-Kanella Panagiotopoulou / Vassilis Pigadas / Minas Bakirtzis / Christos Panagis / Doukas Dardabounis / Panagiota Ntonti

Healthcare, Vol 10, Iss 2117, p

A Prospective Study

2022 Volume 2117

Abstract: 1) Background: While smartphones are among the primary devices used in telemedical applications, smart TV healthcare apps are not prevalent despite smart TVs’ penetrance in home settings. The present study’s objective was to develop and validate the ... ...

Abstract	(1) Background: While smartphones are among the primary devices used in telemedical applications, smart TV healthcare apps are not prevalent despite smart TVs’ penetrance in home settings. The present study’s objective was to develop and validate the first smart TV-based visual acuity (VA) test (Democritus Digital Visual Acuity Test (DDiVAT)) that allows a reliable VA self-assessment. (2) Methods: This is a prospective validation study. DDiVAT introduces several advanced features for reliable VA self-testing; among them: automatic calibration, voice recognition, voice guidance, automatic calculation of VA indexes, and a smart TV-based messaging system. Normal and low vision participants were included in the validation. DDiVAT VA results (VA DDiVAT ) were compared against the ones from: (a) the gold-standard conventional ETDRS (VA ETDRS ), and, (b) an independent ophthalmologist who monitored the self-examination testing (VA RES ). Comparisons were performed by noninferiority test (set at 2.5-letters) and intraclass correlation coefficients (ICCs). DDiVAT’s test-retest reliability was assessed within a 15-day time-window. (3) Results: A total of 300 participants (185 and 115 with normal and low vision, respectively) responded to ETDRS and DDiVAT. Mean difference in letters was −0.05 for VA ETDRS –VA RES , 0.62 for VA RES –VA DDiVAT , and 0.67 for VA ETDRS –VA DDiVAT , significantly lower than the 2.5 letter noninferiority margin. ICCs indicated an excellent level of agreement, collectively and for each group (0.922-0.996). All displayed letters in DDiVAT presented a similar difficulty. The overall accuracy of the voice recognition service was 96.01%. ICC for VA DDiVAT test-retest was 0.957. (4) Conclusions: The proposed DDiVAT presented non-significant VA differences with the ETDRS, suggesting that it can be used for accurate VA self-assessment in telemedical settings, both for normal and low-vision patients.
Keywords	visual acuity test ; smart TV ; smartphone ; home ; validation ; telemedicine ; Medicine ; R
Subject code	150
Language	English
Publishing date	2022-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Outcomes from treatment of metastatic renal-cell carcinoma following failure of first-line anti-VEGF/VEGFR therapy: real-life evidence on the change of the treatment paradigm.

Bamias, Aristotelis / Zakopoulou, Roubini / Tzannis, Kimon / Sakellakis, Minas / Koutsoukos, Konstantinos / Kyriazoglou, Anastasios / Panagiotou, Aikaterini / Armylagos, Stylianos / Rokas, Konstantinos / Gotzias, Dimitrios / Boulouta, Anna / Bozionelou, Vassiliki / Stravodimos, Konstantinos / Varkarakis, Ioannis / Mavroudis, Dimitrios / Dimopoulos, Meletios-Athanasios

Anti-cancer drugs

2022 Volume 34, Issue 3, Page(s) 413–421

Abstract: Recently approved agents for post-vascular endothelial growth factor/post-vascular endothelial growth factor receptor (VEGF/VEGFR) inhibitors treatment of metastatic renal-cell carcinomas (mRCC), such as axitinib, nivolumab, and cabozantinib were shown ... ...

Abstract	Recently approved agents for post-vascular endothelial growth factor/post-vascular endothelial growth factor receptor (VEGF/VEGFR) inhibitors treatment of metastatic renal-cell carcinomas (mRCC), such as axitinib, nivolumab, and cabozantinib were shown to improve prognosis and substituted everolimus in this setting. We studied practice patterns, efficacy, and tolerability of these agents in a real-world series of Greek patients. We included patients with mRCC who received everolimus, axitinib, or nivolumab after progression on first-line anti-VEGF/VEGFRs therapy. Patients were stratified into three groups. Group A received nivolumab with or without cabozantinib at some point in their disease. Group B received axitinib but without nivolumab or cabozantinib. Group C received only everolimus among the four approved agents. Overall, 131 patients were included in the analysis. Everolimus and nivolumab were mainly used in the second line, while axitinib and cabozantinib were mostly used in the third and fourth lines. Median overall survival (OS) from first-line initiation was 8.7 [95% confidence interval (CI), 4-not reached], 3.6 (95% CI, 2-6), and 2.1 years (95% CI, 1.4-2.6) for Group A, B, and C, respectively ( P < 0.001). Median OS from the initiation of second-line therapy was 3.5, 2.7, and 1.3 years, respectively ( P < 0.001). There was no impact of first-line agent or treatment timing on survival. International Metastatic Renal Cell Carcinoma Database Consortium risk stratification was associated with OS. Toxicities observed were within expected frequencies. Grade ≥3 events were rare. Adoption of modern standards in everyday treatment of mRCC results in prolongation of survival. Real-world datasets are the new landmarks of survival for future research.
MeSH term(s)	Humans ; Antineoplastic Agents/therapeutic use ; Axitinib/therapeutic use ; Carcinoma, Renal Cell/drug therapy ; Everolimus/therapeutic use ; Kidney Neoplasms/drug therapy ; Nivolumab/therapeutic use ; Vascular Endothelial Growth Factor A
Chemical Substances	Antineoplastic Agents ; Axitinib (C9LVQ0YUXG) ; cabozantinib (1C39JW444G) ; Everolimus (9HW64Q8G6G) ; Nivolumab (31YO63LBSN) ; Vascular Endothelial Growth Factor A
Language	English
Publishing date	2022-11-16
Publishing country	England
Document type	Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1065301-6
ISSN	1473-5741 ; 0959-4973
ISSN (online)	1473-5741
ISSN	0959-4973
DOI	10.1097/CAD.0000000000001420
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