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Article ; Online: Pulp Revascularization in Three Immature Permanent Mandibular Molars with Necrotic Pulps: A Case Series.

Hajizadeh, Samane / Youzbashi Zadeh, Reza / Vatanparast, Negin

2023 Volume 14, Issue 4, Page(s) 301–305

Abstract: The management of necrotic immature permanent teeth, with blunderbuss root anatomy, is a treatment challenge. Treatment protocols include root canal apexification, creation of an apical plug and recently, regeneration and revascularization protocol (RRP). ...

Abstract	The management of necrotic immature permanent teeth, with blunderbuss root anatomy, is a treatment challenge. Treatment protocols include root canal apexification, creation of an apical plug and recently, regeneration and revascularization protocol (RRP). The latter may have the advantage of continued root development. The main purpose of this case series was to describe the RRP of three necrotic immature permanent mandibular molars with open apices. RRP involved accessing the pulp chamber, disinfecting the root canal system with copious irrigation using 2.5% sodium hypochlorite, applying triple antibiotic paste/calcium hydroxide as an intracanal medicament and sealing the access cavity. After three weeks, the medicament was removed and the apex was irritated with a K-file to induce blood-clot formation inside the pulp canal space; which would provide a suitable matrix for new tissue in-growth. Mineral trioxide aggregate was employed to seal the canal orifices before final restoration. During follow-up sessions, patients were asymptomatic and root development seemed to be in progress. Therefore, it seems that with proper case selection, regeneration and revascularization can be considered as a suitable alternative for the apexification of necrotic immature teeth.
Language	English
Publishing date	2023-02-06
Publishing country	Iran
Document type	Case Reports
ZDB-ID	2684659-7
ISSN	2008-2746 ; 2008-2746
ISSN (online)	2008-2746
ISSN	2008-2746
DOI	10.22037/iej.v14i4.24930
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Long-Term Prognosis in Patients with Coronary Slow Flow.

Mikaeilvand, Amir / Hajizadeh, Reza / Bateni, Amin / Yahyapour, Zhivar

The journal of Tehran Heart Center

2023 Volume 17, Issue 4, Page(s) 202–206

Abstract: Background: Coronary slow flow (CSF) is defined as decreased coronary blood circulation velocity and delayed opacification of contrast media during angiography. Evidence is insufficient regarding the course and prognosis of CSF patients. Long-term ... ...

Abstract	Background: Coronary slow flow (CSF) is defined as decreased coronary blood circulation velocity and delayed opacification of contrast media during angiography. Evidence is insufficient regarding the course and prognosis of CSF patients. Long-term follow-up can help better understand the physiopathology and outcome of CSF. Accordingly, we assessed the long-term outcomes of CSF patients in this study. Methods: This retrospective cohort study was carried out on 213 CSF patients consecutively admitted to a tertiary health care center from April 2012 through March 2021. After data collection from the patients' files, follow-up was done via telephone call invitations and assessments of existing data in the outpatient cardiology clinic. The comparative analysis was conducted using a logistic regression test. Results: The mean follow-up length was 66.26±15.32 months, 105 patients (52.2%) were male, and the mean age of the patients was 53.81±11.91 years. The left anterior descending was the main affected artery (42.8%). At long-term follow-up, 19 patients (9.5%) required repeated angiography. Three patients (1.5%) had a myocardial infarction and 5 (2.5%) died from cardiovascular etiologies. Three patients (1.5%) underwent percutaneous coronary intervention. No patient required coronary artery bypass grafting. The need for a second angiography had no association with sex, symptoms, and echocardiographic findings. Conclusion: The long-term outcome of CSF patients is good, but their follow-up is necessary for the early diagnosis of cardiovascular-related adverse events.
Language	English
Publishing date	2023-04-18
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2476998-8
ISSN	2008-2371 ; 1735-5370 ; 1735-8620
ISSN (online)	2008-2371
ISSN	1735-5370 ; 1735-8620
DOI	10.18502/jthc.v17i4.11608
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Article ; Online: Associations of circulating advanced glycation end products and their soluble receptors with cancer risk: A systematic review and meta-analysis of observational studies.

Hajizadeh-Sharafabad, Fatemeh / Shojaei-Zarghani, Sara / Sharifi-Zahabi, Elham / Gerami, Farzad / Pashaei, Mohammad Reza

Glycoconjugate journal

2024 Volume 41, Issue 1, Page(s) 35–46

Abstract: Advanced glycation end products (AGE) in complex with their receptors (RAGE) cause a chronic inflammatory state in the body, which is the major mechanism in cancer development. This study aimed to conduct a systematic review and meta-analysis on the ... ...

Abstract	Advanced glycation end products (AGE) in complex with their receptors (RAGE) cause a chronic inflammatory state in the body, which is the major mechanism in cancer development. This study aimed to conduct a systematic review and meta-analysis on the observational studies investigating the association between AGEs / sRAGE and cancer incidence. The PubMed, Scopus, and Web of Science databases were comprehensively searched to identify papers focused on the associations of sRAGE and AGEs with cancer incidence up to May 2023. Eight studies with a total of 7690 participants were included in the analysis to evaluate the association between circulating sRAGE and cancer incidence. The results indicated that circulating sRAGE (per 100 ng/L) had a significant inverse association with cancer incidence (RR 0.977; 95% CI 0.956, 0.999; p = 0.036; I
MeSH term(s)	Humans ; Biomarkers ; Glycation End Products, Advanced ; Inflammation ; Neoplasms/epidemiology ; Observational Studies as Topic ; Receptor for Advanced Glycation End Products
Chemical Substances	Biomarkers ; Glycation End Products, Advanced ; Receptor for Advanced Glycation End Products
Language	English
Publishing date	2024-03-18
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	283770-5
ISSN	1573-4986 ; 0282-0080
ISSN (online)	1573-4986
ISSN	0282-0080
DOI	10.1007/s10719-024-10147-w
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Article: Is the New Coronavirus Disease (COVID-19) Pandemic Halted by Malaria Epidemics?

Hajizadeh, Reza / Behnemoon, Mahsa

The archives of bone and joint surgery

2020 Volume 8, Issue Suppl 1, Page(s) 319–320

Keywords	covid19
Language	English
Publishing date	2020-06-06
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2782053-1
ISSN	2345-461X ; 2345-4644
ISSN (online)	2345-461X
ISSN	2345-4644
DOI	10.22038/abjs.2020.47662.2336
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Article ; Online: Evaluation of Apoptotic Gene Expression in Hepatoma Cell Line (HepG2) Following Nisin Treatment.

Zainodini, Nahid / Hajizadeh, Mohammad Reza / Mirzaei, Mohammad Reza

Asian Pacific journal of cancer prevention : APJCP

2021 Volume 22, Issue 5, Page(s) 1413–1419

Abstract: Objective: The present study aims to examine the effects of nisin on the survival and apoptosis of the hepatoma cell line HepG2 and to investigate possible apoptosis pathways activated by nisin.: Materials and methods: For this purpose, viability and ...

Abstract	Objective: The present study aims to examine the effects of nisin on the survival and apoptosis of the hepatoma cell line HepG2 and to investigate possible apoptosis pathways activated by nisin. Materials and methods: For this purpose, viability and apoptosis of the cells were accomplished by the nisin treatment using the MTT assay and Annexin-V-fluorescein/propidium iodide (PI) double staining, respectively. Additionally, the human apoptosis PCR array was performed to determine pathways or genes activated by nisin during possible apoptosis. Results: The results of the present study showed that nisin was able to decrease cell viability (IC50 ~ 40 µg/ml) in a dose-dependent manner and could induce apoptosis in HepG2 cells. PCR data indicated a considerable increase in the expression of genes, such as caspase and BCL2 families, involved in the induction of apoptosis. Conclusions: The data from this study showed that overexpression of genes involved in the intrinsic pathway of apoptosis, especially caspase-9 and BID, increased apoptosis in HepG2 cells treated by nisin, compared to the control group.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Proliferation ; Gene Expression Regulation, Neoplastic/drug effects ; Hep G2 Cells ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Nisin/pharmacology
Chemical Substances	Anti-Bacterial Agents ; Biomarkers, Tumor ; Nisin (1414-45-5)
Language	English
Publishing date	2021-05-01
Publishing country	Thailand
Document type	Evaluation Study ; Journal Article
ZDB-ID	2218955-5
ISSN	2476-762X ; 1513-7368
ISSN (online)	2476-762X
ISSN	1513-7368
DOI	10.31557/APJCP.2021.22.5.1413
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Article ; Online: A magnetic X-band frequency microwave nanoabsorbent made of iron oxide/halloysite nanostructures combined with polystyrene.

Jelodar, Diana Fallah / Rouhi, Mojtaba / Taheri-Ledari, Reza / Hajizadeh, Zoleikha / Maleki, Ali

RSC advances

2023 Volume 13, Issue 10, Page(s) 6643–6655

Abstract: A novel nanocomposite has been designed and fabricated through ... ...

Abstract	A novel nanocomposite has been designed and fabricated through an
Language	English
Publishing date	2023-02-27
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d2ra08339f
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Article: A new species of Olopachys Berlese (Acari: Pachylaelapidae) from Iran with a key to the world species

Hajizadeh, Jalil / Hosseini, Reza

International journal of acarology. 2020 Oct. 02, v. 46, no. 7

2020

Abstract: A new species, Olopachys masani sp. nov. (Mesostigmata: Pachylaelapidae), is described based on adult female and male specimens collected from soil in Guilan province, northern Iran. Two identification keys are provided, one for all known species of ... ...

Abstract	A new species, Olopachys masani sp. nov. (Mesostigmata: Pachylaelapidae), is described based on adult female and male specimens collected from soil in Guilan province, northern Iran. Two identification keys are provided, one for all known species of Olopachys, and the other for species recorded from Iran. Collection details for pachylaelapid mites associated with citrus orchards in Guilan province Iran are also provided. http://www.zoobank.org/urn:lsid:zoobank.org:pub:A6C51443-0B15-4DC3-A428-A3E247306990
Keywords	Citrus ; Mesostigmata ; acarology ; adults ; females ; males ; new species ; soil ; Iran
Language	English
Dates of publication	2020-1002
Size	p. 530-537.
Publishing place	Taylor & Francis
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2476319-6
ISSN	1945-3892 ; 0164-7954
ISSN (online)	1945-3892
ISSN	0164-7954
DOI	10.1080/01647954.2020.1819411
Database	NAL-Catalogue (AGRICOLA)

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Article: The Effect of Cytotoxicity and Antimicrobial of Synthesized CuO NPs from Propolis on HEK-293 Cells and

Seyyed Hajizadeh, Yasamin / Babapour, Ebrahim / Harzandi, Naser / Yazdanian, Mohsen / Ranjbar, Reza

Evidence-based complementary and alternative medicine : eCAM

2023 Volume 2023, Page(s) 1430839

Abstract: Background: Drug resistance is currently possible anywhere in the world. Due to the discovery of antimicrobials, medicine, and health have made tremendous advances over the past several decades.: Aim: This research evaluated the antimicrobial and ... ...

Abstract	Background: Drug resistance is currently possible anywhere in the world. Due to the discovery of antimicrobials, medicine, and health have made tremendous advances over the past several decades. Aim: This research evaluated the antimicrobial and cytotoxicity effects of green synthesis of copper oxide nanoparticles (CuO NPs) on Results: Synthesized CuO NPs using propolis extracts from Khalkhal (sample 1) and Gillan (sample 2) showed -13.2 and -14.4 mV, respectively. The hydrodynamic sizes of well-dispersed samples 1 and 2 were 3124.9 nm and 1726.7 nm, respectively. According to BET analysis, samples 1 and 2 had 5.37 and 8.45 m Conclusion: There was no evidence of cytotoxicity in the samples. In addition, results showed that the green synthesized CuO NPs from Khalkhal propolis were effective against
Language	English
Publishing date	2023-02-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2023/1430839
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Article ; Online: Umbilical cord blood thyroid hormones are inversely related to telomere length and mitochondrial DNA copy number.

Ohadi, Homa / Khalili, Parvin / Abasnezhad Kasrineh, Farzaneh / Esmaeili, Ozra Sadat / Esmaeili Ranjbar, Faeze / Manshoori, Azita / Hajizadeh, Mohammad Reza / Jalali, Zahra

Scientific reports

2024 Volume 14, Issue 1, Page(s) 3164

Abstract: Hypothyroidism has been linked to reduced mortality rate and increased lifespan and health span. Telomere shortening, enhanced oxidative stress, and reduced cellular mitochondrial content are important hallmarks of aging shown to be related to age- ... ...

Abstract	Hypothyroidism has been linked to reduced mortality rate and increased lifespan and health span. Telomere shortening, enhanced oxidative stress, and reduced cellular mitochondrial content are important hallmarks of aging shown to be related to age-associated diseases. It was proposed that the status of these markers in early life can be predictive of lifespan and the predisposition to certain age-associated disease in adulthood. Animal studies indicated that prenatal injection of thyroid hormones affects postnatal telomere length. Here, we sought to determine whether thyroid hormones TSH and fT4 are related to the telomere length, mitochondrial DNA copy number (mtDNAcn), and oxidative stress resistance marker GPX in the cord blood of newborns. In this study, we analyzed 70 mothers (18-42 years) and neonate dyads born in 2022 at the Nik Nafs maternity Hospital in Rafsanjan. The relative telomere length (RTL) and mtDNAcn were measured in the genomic DNA of cord blood leukocytes using real-time PCR. GPX enzyme activity was measured in the serum using colorimetric assays. In this study the correlation between these markers and the cord blood TSH and fT4 hormones were assessed using regression models. We found a reverse relationship between TSH levels and RTL in the cord blood of neonates. Additionally, our results displayed increased TSH levels associated with enhanced GPX activity. Regarding the mitochondrial DNA copy number, we found an indirect relationship between fT4 level and mtDNAcn only in male newborns. Future analyses of various oxidative stress markers, mitochondrial biogenesis status, telomerase activity, and the level of DNA damage are warranted to demonstrate the underlying mechanism of our observations.
MeSH term(s)	Humans ; Infant, Newborn ; Animals ; Male ; Female ; Pregnancy ; Child, Preschool ; DNA, Mitochondrial/genetics ; Fetal Blood ; DNA Copy Number Variations ; Thyroid Hormones ; Telomere/genetics ; Thyrotropin/genetics
Chemical Substances	DNA, Mitochondrial ; Thyroid Hormones ; Thyrotropin (9002-71-5)
Language	English
Publishing date	2024-02-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-53628-6
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Article ; Online: Evaluation of epigenetic-related gene expression (DNMT, HDAC1) in Iranian patients with systemic lupus erythematosus.

Abbasifard, Mitra / Mohammadiranjbar, Fahimeh / Mohammad-Sadeghipour, Maryam / Mahmoodi, Mehdi / Hassanshahi, Gholamhossein / Swann, Jennifer / Zarei, Sadegh / Hosseiniara, Reza / Hajizadeh, Mohammad Reza

Reumatologia clinica

2023 Volume 19, Issue 7, Page(s) 358–362

Abstract: Background: Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system abnormally reacts against cells and tissues leading to inflammation. Epigenetic alterations, including DNA methylation and histone modification, have ... ...

Abstract	Background: Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system abnormally reacts against cells and tissues leading to inflammation. Epigenetic alterations, including DNA methylation and histone modification, have critical effects on autoimmune disease and SLE pathogenesis via dysregulation of critical genes. Aims: The purpose of this study was to evaluate the epigenetic-related gene expression of DNA methyltransferase (DNMT) and histone deacetylase 1 (HDAC1) in Iranian patients with SLE. Methods: This matched case-control study included 16 people with SLE and 16 healthy people who were referred to the Rafsanjani rheumatology clinic, in southeast Iran. The expression of DNMT and HDAC1 genes was measured through a real-time PCR assay of blood samples. Results: DNMT gene expression did not differ significantly between SLE and healthy groups (P=0.21). In contrast, HDAC1 gene expression was enhanced in the SLE group, but this enhancement failed to reach statistical significance (P=0.94). Conclusion: The results of this study suggest that overexpression of HDAC1 could serve as a diagnostic for SLE disease. Additional studies with larger sample sizes are required to confirm our findings. Evaluation of other genes related to SLE disease is essential and may help to make an accurate diagnosis of the disease.
MeSH term(s)	Humans ; Case-Control Studies ; Epigenesis, Genetic ; Gene Expression ; Histone Deacetylase 1/genetics ; Histone Deacetylase 1/metabolism ; Iran ; Lupus Erythematosus, Systemic/diagnosis
Chemical Substances	HDAC1 protein, human (EC 3.5.1.98) ; Histone Deacetylase 1 (EC 3.5.1.98) ; DNMT1 protein, human (EC 2.1.1.37)
Language	English
Publishing date	2023-09-03
Publishing country	Spain
Document type	Journal Article
ISSN	2173-5743
ISSN (online)	2173-5743
DOI	10.1016/j.reumae.2022.12.006
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