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  1. Article: Calculating Linkage Intensities from F(3) Data.

    Immer, F R

    Genetics

    2007  Volume 19, Issue 2, Page(s) 119–136

    Language English
    Publishing date 2007-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2167-2
    ISSN 1943-2631 ; 0016-6731
    ISSN (online) 1943-2631
    ISSN 0016-6731
    DOI 10.1093/genetics/19.2.119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Organspende und -transplantation. Aktuelle Entwicklungen in der Schweiz

    Immer, Franz

    Hausarzt-Praxis

    2019  Volume 14, Issue 7, Page(s) 1

    Language German
    Document type Article
    ZDB-ID 2229849-6
    ISSN 1661-6197
    Database Current Contents Medicine

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  3. Article: Aktuelle Entwicklungen der Organspende

    Immer, Franz / Kreis, Jeanne

    Anästhesie-Journal = Journal d'anesthésie

    2021  Volume 33, Issue 1, Page(s) 24–25

    Abstract: Die Schweizerische Nationale Stiftung für Organspende und Transplantation Swisstransplant blickt auf ein ereignisreiches Jahr zurück. Die Coronapandemie, politische Debatten um die Widerspruchslösung sowie die nach wie vor hohe Ablehnungsrate in ... ...

    Abstract Die Schweizerische Nationale Stiftung für Organspende und Transplantation Swisstransplant blickt auf ein ereignisreiches Jahr zurück. Die Coronapandemie, politische Debatten um die Widerspruchslösung sowie die nach wie vor hohe Ablehnungsrate in Angehörigengesprächen stellten grosse Herausforderungen dar. Mit 146 postmortalen Organspendern ist die Spenderate im Vergleich zum Vorjahr aber nur leicht zurückgegangen.
    Keywords Organspende
    Language German
    Document type Article
    ZDB-ID 2303083-5
    Database bibnet.org

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  4. Article ; Online: Organ donation after circulatory death in Switzerland: slow but constant progress.

    Immer, Franz F

    Swiss medical weekly

    2015  Volume 145, Page(s) w14062

    MeSH term(s) Clinical Protocols ; Death ; Health Policy ; Heart Arrest ; Humans ; Switzerland ; Tissue and Organ Procurement/classification ; Tissue and Organ Procurement/standards
    Language English
    Publishing date 2015
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2036179-8
    ISSN 1424-3997 ; 1424-7860
    ISSN (online) 1424-3997
    ISSN 1424-7860
    DOI 10.4414/smw.2015.14062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Aktuelle Entwicklungen auf dem Gebiet der Organspende und Transplantation in der Schweiz

    Immer, Franz F.

    Anästhesie-Journal = Journal d'anesthésie

    2017  , Issue 2, Page(s) 24–27

    Keywords Praxis ; Anästhesie
    Language German
    Document type Article
    ZDB-ID 2303083-5
    Database bibnet.org

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  6. Article ; Online: Utilization of organs to pediatric heart transplant recipients.

    Schweiger, Martin / Immer, Franz F

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2018  Volume 38, Issue 3, Page(s) 239–240

    MeSH term(s) Child ; Heart Transplantation ; Humans ; Tissue Donors
    Language English
    Publishing date 2018-12-14
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2018.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Organ donation after circulatory death as compared with organ donation after brain death in Switzerland - an observational study.

    Elmer, Andreas / Rohrer, Mara-Lisa / Benden, Christian / Krügel, Nathalie / Beyeler, Franziska / Immer, Franz F

    Swiss medical weekly

    2022  Volume 152, Page(s) w30139

    Abstract: Aims of the study: Organ donation after circulatory death (DCD) was reintroduced in Switzerland in 2011 and accounts for a third of deceased organ donors today. Controversy persists if DCD transplants are of similar quality to transplants following ... ...

    Abstract Aims of the study: Organ donation after circulatory death (DCD) was reintroduced in Switzerland in 2011 and accounts for a third of deceased organ donors today. Controversy persists if DCD transplants are of similar quality to transplants following donation after brain death (DBD), mainly due to warm ischaemia time DCD organs are exposed to. We compared DCD with DBD in Switzerland.
    Methods: Data on deceased adults who were referred to and approved for organ donation from 1 September 2011 to 31 December 2019 were retrospectively analysed (217 DCD, 840 DBD donors). We compared DCD and DBD donor/organ characteristics, transplant rates of lungs, liver, kidneys, and pancreas, and early liver and kidney graft function in the recipient. The effect of DCD/DBD on transplant rates (organ transplanted or not) and 72-hour recipient graft function (moderate/good vs delayed graft function / organ loss) was analysed using multivariable logistic regression. Among utilised DCD donors, we analysed the effect of functional warm ischaemia time (FWIT) and donor age on 72-hour post-transplant liver and kidney graft function, also using multivariable logistic regression.
    Results: DCD donors were more often male (64.5% vs 56.8% p = 0.039), presented with heart disease (36.4% vs 25.5%, p <0.001), were resuscitated before hospital admission (41.9% vs 30.7%, p = 0.006), and died from anoxia (41.9% vs 23.9%). Kidney function before transplantation was comparable, lung, liver and pancreas function were poorer in DCD than DBD. Eighty-one and 91% of approved DCD and DBD donors were utilised (p <0.001). Median FWIT in DCD was 29 minutes (interquartile range 25-35). DCD transplant rates ranged from 4% (pancreas) to 73% (left kidney) and were all lower compared with DBD. Seventy-two-hour liver graft function was comparable between DCD and DBD (94.2% vs 96.6% moderate/good, p = 0.199). DCD kidney transplants showed increased risk of delayed graft function or early organ loss (odds ratios 8.32 and 5.05; 95% confidence intervals CI 5.28-13.28 and 3.22-7.95; both p <0.001, for left and right kidney transplants, respectively). No negative effect of prolonged FWIT or higher donor age was detected.
    Conclusion: Despite less favourable donor/organ characteristics compared with donation after brain death, donation after circulatory death donors are increasingly referred and today provide an important source for scarce transplants in Switzerland. We identified a higher risk for delayed graft function or early organ loss for DCD kidney transplants, but not for DCD liver transplants. When carefully selected and allowed for other risk factors in organ allocation, prolonged functional warm ischaemia time or higher age in donation after circulatory death does not seem to be associated with impaired graft function early after transplantation.
    MeSH term(s) Adult ; Aged ; Brain Death ; Death ; Graft Survival ; Humans ; Male ; Retrospective Studies ; Switzerland ; Tissue Donors ; Tissue and Organ Procurement
    Language English
    Publishing date 2022-02-18
    Publishing country Switzerland
    Document type Journal Article ; Observational Study
    ZDB-ID 2036179-8
    ISSN 1424-3997 ; 1424-7860
    ISSN (online) 1424-3997
    ISSN 1424-7860
    DOI 10.4414/smw.2022.w30132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Wie frei ist die Meinungsfreiheit?

    Immer, Franz

    Krankenpflege. Soins infirmiers

    2013  Volume 106, Issue 9, Page(s) 29

    Title translation How free is freedom of expression?.
    MeSH term(s) Attitude of Health Personnel ; Freedom ; Humans ; Nurse's Role/psychology ; Switzerland ; Tissue Donors/psychology ; Tissue and Organ Procurement
    Language German
    Publishing date 2013
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 80459-9
    ISSN 0253-0465
    ISSN 0253-0465
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Current status and further potential of lung donation after circulatory death.

    Ehrsam, Jonas P / Benden, Christian / Immer, Franz F / Inci, Ilhan

    Clinical transplantation

    2021  Volume 35, Issue 7, Page(s) e14335

    Abstract: Chronic organ shortage remains the most limiting factor in lung transplantation. To overcome this shortage, a minority of centers have started with efforts to reintroduce donation after circulatory death (DCD). This review aims to evaluate the ... ...

    Abstract Chronic organ shortage remains the most limiting factor in lung transplantation. To overcome this shortage, a minority of centers have started with efforts to reintroduce donation after circulatory death (DCD). This review aims to evaluate the experimental background, the current international clinical experience, and the further potential and challenges of the different DCD categories. Successful strategies have been implemented to reduce the problems of warm ischemic time, thrombosis after circulatory arrest, and difficulties in organ assessment, which come with DCD donation. From the currently reported results, controlled-DCD lungs are an effective and safe method with good mid-term and even long-term survival outcomes comparable to donation after brain death (DBD). Primary graft dysfunction and onset of chronic allograft dysfunction seem also comparable. Thus, controlled-DCD lungs should be ceased to be treated as marginal and instead be promoted as an equivalent alternative to DBD. A wide implementation of controlled-DCD-lung donation would significantly decrease the mortality on the waiting list. Therefore, further efforts in establishment of legislation and logistics are crucial. With regard to uncontrolled DCD, more data are needed analyzing long-term outcomes. To help with the detailed assessment and improvement of uncontrolled or otherwise questionable grafts after retrieval, ex-vivo lung perfusion is promising.
    MeSH term(s) Brain Death ; Death ; Graft Survival ; Humans ; Lung ; Lung Transplantation ; Retrospective Studies ; Tissue Donors ; Tissue and Organ Procurement
    Language English
    Publishing date 2021-05-18
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/ctr.14335
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  10. Article: CME-Fortbildung. Organspende und -transplantation. Gesetzliche Regelung und Organisation in der Schweiz / CME-Fortbildungsfragen zu Organspende

    Elmer, Andreas / Immer, Franz F.

    Hausarzt-Praxis

    2019  Volume 14, Issue 7, Page(s) 12/18

    Language German
    Document type Article
    ZDB-ID 2229849-6
    ISSN 1661-6197
    Database Current Contents Medicine

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