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  1. Book: Chih wu chi chih wu sheng li

    Yang, Ta-ch'i

    (Chih yeh kao chi chung hsüeh chiao tsai)

    1989  

    Title translation Plants and plant physiology.
    Author's details Chu pien Yang Ta-ch'i ; pien hsieh Yang Ta-ch'i ... [et al.]
    Series title Chih yeh kao chi chung hsüeh chiao tsai
    Keywords Plant physiology.
    Language Chinese
    Size 2, 5, 378 p. :, ill. ;, 19 cm.
    Edition Ti 1 pan.
    Publisher Ch'ung-ch'ing ch'u pan she ; Yün-nan chiao yü ch'u pan she ; Ssu-ch'uan chiao yü ch'u pan she
    Publishing place Ch'ung-ch'ing
    Document type Book
    ISBN 7536609477 ; 9787536609471
    Database NAL-Catalogue (AGRICOLA)

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  2. Book: Jou yung chai chi sheng chʻan chih nan

    Liu, Kuo-tse / Yang, Hung-mei / Jen, Chung-chʻi

    (Nung tsün chüan yeh hu yang chih tsʻung shu)

    1990  

    Title translation Reference book on production of chicks.
    Author's details Liu Kuo-tse, Yang Hung-mei, Jen Chung-chʻi pien
    Series title Nung tsün chüan yeh hu yang chih tsʻung shu
    Keywords Chickens.
    Language Chinese
    Size 2, 2, 209 p. :, ill. ;, 19 cm.
    Edition Ti 1 pan.
    Publisher Shang-hsi kʻo hsüeh chi shu chʻu pan she ; Hsin hua shu tien Shang-hai fa hsing so fa hsing
    Publishing place Shang-hai
    Document type Book
    ISBN 7532318648 ; 9787532318643
    Database NAL-Catalogue (AGRICOLA)

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  3. Book: Chih wu yu i wei sheng wu ti yen chiu ho ying yu

    Yan, Ssu-chʻi / Yang, Ta-chi / Hsiao, Chien-kuo

    shui tao feng shou chün

    1992  

    Title variant Researches and application on the plant beneficial microorganisms
    Author's details chu pien Yan Ssu-chʻi ; fu chu pien Yang Ta-chi, Hsiao Chien-kuo = Researches and application on the plant beneficial microorganisms : rice growth-promoting rhizobacteria / chief editor Yan Siqi ; deputy chief editors Yang Daqi, Xiao Jianguo
    Keywords Rice/Growth. ; Bacillus cereus. ; Plant growth-promoting rhizobacteria.
    Language Chinese
    Size 4, 122 p., [10] p. of plates :, ill. (some col.) ;, 26 cm.
    Edition Ti 1 pan.
    Publisher Kʻo hsüeh chi shu wen hsien chʻu pan she ; Hsin hua shu tien Chʻung-chʻing fa hsing so fa hsing
    Publishing place Pei-ching
    Document type Book
    Note Summary and added table of contents also in English.
    ISBN 7502318100 ; 9787502318109
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Identification of New Antiseizure Medication Candidates in Preclinical Animal Studies.

    Yang, Chih-Sheng / Wu, Man-Chun / Lai, Ming-Chi / Wu, Sheng-Nan / Huang, Chin-Wei

    International journal of molecular sciences

    2023  Volume 24, Issue 17

    Abstract: Epilepsy is a multifactorial neurologic disease that often leads to many devastating disabilities and an enormous burden on the healthcare system. Until now, drug-resistant epilepsy has presented a major challenge for approximately 30% of the epileptic ... ...

    Abstract Epilepsy is a multifactorial neurologic disease that often leads to many devastating disabilities and an enormous burden on the healthcare system. Until now, drug-resistant epilepsy has presented a major challenge for approximately 30% of the epileptic population. The present article summarizes the validated rodent models of seizures employed in pharmacological researches and comprehensively reviews updated advances of novel antiseizure candidates in the preclinical phase. Newly discovered compounds that demonstrate antiseizure efficacy in preclinical trials will be discussed in the review. It is inspiring that several candidates exert promising antiseizure activities in drug-resistant seizure models. The representative compounds consist of derivatives of hybrid compounds that integrate multiple approved antiseizure medications, novel positive allosteric modulators targeting subtype-selective γ-Aminobutyric acid type A receptors, and a derivative of cinnamamide. Although the precise molecular mechanism, pharmacokinetic properties, and safety are not yet fully clear in every novel antiseizure candidate, the adapted approaches to design novel antiseizure medications provide new insights to overcome drug-resistant epilepsy.
    MeSH term(s) Animals ; Seizures/drug therapy ; Drug Resistant Epilepsy
    Language English
    Publishing date 2023-08-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241713143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Inhibitory Efficacy of Main Components of

    Lin, Cheng-Han / Chang, Ho-Ju / Lin, Meng-Wei / Yang, Xin-Rui / Lee, Che-Hsiung / Lin, Chih-Sheng

    International journal of molecular sciences

    2024  Volume 25, Issue 5

    Abstract: Blocking the interaction between the SARS-CoV-2 spike protein and the human angiotensin-converting enzyme II (hACE2) protein serves as a therapeutic strategy for treating COVID-19. Traditional Chinese medicine (TCM) treatments containing bioactive ... ...

    Abstract Blocking the interaction between the SARS-CoV-2 spike protein and the human angiotensin-converting enzyme II (hACE2) protein serves as a therapeutic strategy for treating COVID-19. Traditional Chinese medicine (TCM) treatments containing bioactive products could alleviate the symptoms of severe COVID-19. However, the emergence of SARS-CoV-2 variants has complicated the process of developing broad-spectrum drugs. As such, the aim of this study was to explore the efficacy of TCM treatments against SARS-CoV-2 variants through targeting the interaction of the viral spike protein with the hACE2 receptor. Antiviral activity was systematically evaluated using a pseudovirus system.
    MeSH term(s) Humans ; SARS-CoV-2 ; Scutellaria baicalensis ; COVID-19 ; Spike Glycoprotein, Coronavirus ; Flavones ; Angiotensins ; Protein Binding
    Chemical Substances spike protein, SARS-CoV-2 ; Spike Glycoprotein, Coronavirus ; Flavones ; Angiotensins
    Language English
    Publishing date 2024-03-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25052935
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: A Low-Cost Fertilizer Medium Supplemented with Urea for the Lutein Production of

    Kuo, Chiu-Mei / Yang, Yi-Chun / Zhang, Wen-Xin / Wu, Jia-Xun / Chen, Yu-Tso / Lin, Cheng-Han / Lin, Meng-Wei / Lin, Chih-Sheng

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 5

    Abstract: This study aimed to investigate the use of organic fertilizers instead of modified f/2 medium ... ...

    Abstract This study aimed to investigate the use of organic fertilizers instead of modified f/2 medium for
    Language English
    Publishing date 2023-05-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10050594
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bulging Tumor in the Distal Rectum.

    Huang, Chih-Sheng / Huang, Li-Kuo / Yang, Jr-Di

    Gastroenterology

    2020  Volume 158, Issue 8, Page(s) 2061–2062

    MeSH term(s) Adenocarcinoma/diagnostic imaging ; Adenocarcinoma/pathology ; Adenocarcinoma/therapy ; Aged ; Androgen Antagonists/therapeutic use ; Biopsy ; Chemotherapy, Adjuvant ; Humans ; Male ; Neoplasm Invasiveness ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/therapy ; Rectum/diagnostic imaging ; Rectum/pathology ; Sigmoidoscopy ; Tomography, X-Ray Computed ; Transurethral Resection of Prostate
    Chemical Substances Androgen Antagonists
    Language English
    Publishing date 2020-03-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2020.02.049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Hybrid proximal linearized algorithm for the split DC program in infinite-dimensional real Hilbert spaces.

    Chuang, Chih-Sheng / Yang, Pei-Jung

    Journal of inequalities and applications

    2018  Volume 2018, Issue 1, Page(s) 250

    Abstract: To be the best of our knowledge, the convergence theorem for the DC program and split DC program are proposed in finite-dimensional real Hilbert spaces or Euclidean spaces. In this paper, to study the split DC program, we give a hybrid proximal ... ...

    Abstract To be the best of our knowledge, the convergence theorem for the DC program and split DC program are proposed in finite-dimensional real Hilbert spaces or Euclidean spaces. In this paper, to study the split DC program, we give a hybrid proximal linearized algorithm and propose related convergence theorems in the settings of finite- and infinite-dimensional real Hilbert spaces, respectively.
    Language English
    Publishing date 2018-09-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2028512-7
    ISSN 1029-242X ; 1025-5834
    ISSN (online) 1029-242X
    ISSN 1025-5834
    DOI 10.1186/s13660-018-1840-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: ACE2 and a Traditional Chinese Medicine Formula NRICM101 Could Alleviate the Inflammation and Pathogenic Process of Acute Lung Injury

    Cheng-Han Lin / Yi-Ju Chen / Meng-Wei Lin / Ho-Ju Chang / Xin-Rui Yang / Chih-Sheng Lin

    Medicina, Vol 59, Iss 1554, p

    2023  Volume 1554

    Abstract: COVID-19 is a highly transmittable respiratory illness caused by SARS-CoV-2, and acute lung injury (ALI) is the major complication of COVID-19. The challenge in studying SARS-CoV-2 pathogenicity is the limited availability of animal models. Therefore, it ...

    Abstract COVID-19 is a highly transmittable respiratory illness caused by SARS-CoV-2, and acute lung injury (ALI) is the major complication of COVID-19. The challenge in studying SARS-CoV-2 pathogenicity is the limited availability of animal models. Therefore, it is necessary to establish animal models that can reproduce multiple characteristics of ALI to study therapeutic applications. The present study established a mouse model that has features of ALI that are similar to COVID-19 syndrome to investigate the role of ACE2 and the administration of the Chinese herbal prescription NRICM101 in ALI. Mice with genetic modifications, including overexpression of human ACE2 (K18-hACE2 TG) and absence of ACE2 (mACE2 KO), were intratracheally instillated with hydrochloric acid. The acid intratracheal instillation induced severe immune cell infiltration, cytokine storms, and pulmonary disease in mice. Compared with K18-hACE2 TG mice, mACE2 KO mice exhibited dramatically increased levels of multiple inflammatory cytokines (IL-6 and TNF-α) in bronchoalveolar lavage fluid, histological evidence of lung injury, and dysregulation of MAPK and MMP activation. In mACE2 KO mice, NRICM101 could ameliorate the disease progression of acid-induced ALI. In conclusion, the established mouse model provided an effective platform for researchers to investigate pathological mechanisms and develop therapeutic strategies for ALI, including COVID-19-related ALI.
    Keywords angiotensin-converting enzyme type II (ACE2) ; acute lung injury (ALI) ; animal model ; traditional Chinese medicine ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: ACE2

    Lin, Cheng-Han / Chen, Yi-Ju / Lin, Meng-Wei / Chang, Ho-Ju / Yang, Xin-Rui / Lin, Chih-Sheng

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 9

    Abstract: COVID-19 is a highly transmittable respiratory illness caused by SARS-CoV-2, and acute lung injury (ALI) is the major complication of COVID-19. The challenge in studying SARS-CoV-2 pathogenicity is the limited availability of animal models. Therefore, it ...

    Abstract COVID-19 is a highly transmittable respiratory illness caused by SARS-CoV-2, and acute lung injury (ALI) is the major complication of COVID-19. The challenge in studying SARS-CoV-2 pathogenicity is the limited availability of animal models. Therefore, it is necessary to establish animal models that can reproduce multiple characteristics of ALI to study therapeutic applications. The present study established a mouse model that has features of ALI that are similar to COVID-19 syndrome to investigate the role of ACE2 and the administration of the Chinese herbal prescription NRICM101 in ALI. Mice with genetic modifications, including overexpression of human ACE2 (K18-hACE2 TG) and absence of ACE2 (mACE2 KO), were intratracheally instillated with hydrochloric acid. The acid intratracheal instillation induced severe immune cell infiltration, cytokine storms, and pulmonary disease in mice. Compared with K18-hACE2 TG mice, mACE2 KO mice exhibited dramatically increased levels of multiple inflammatory cytokines (IL-6 and TNF-α) in bronchoalveolar lavage fluid, histological evidence of lung injury, and dysregulation of MAPK and MMP activation. In mACE2 KO mice, NRICM101 could ameliorate the disease progression of acid-induced ALI. In conclusion, the established mouse model provided an effective platform for researchers to investigate pathological mechanisms and develop therapeutic strategies for ALI, including COVID-19-related ALI.
    Language English
    Publishing date 2023-08-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59091554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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