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Article ; Online: A Review of Pathogens Transmitted by the Container-Inhabiting Mosquitoes, Aedes Albopictus, A Global Public Health Threat.

Zhang, Wenrong / Wang, Jinna / Liu, Qinmei / Gong, Zhenyu

China CDC weekly

2023 Volume 5, Issue 44, Page(s) 984–990

Abstract: Dengue virus (DENV), Chikungunya virus (CHIKV), and Zika virus (ZIKV) are highly pathogenic human arboviruses transmitted by ... ...

Abstract	Dengue virus (DENV), Chikungunya virus (CHIKV), and Zika virus (ZIKV) are highly pathogenic human arboviruses transmitted by the
Language	English
Publishing date	2023-11-27
Publishing country	China
Document type	Journal Article ; Review
ISSN	2096-7071
ISSN (online)	2096-7071
DOI	10.46234/ccdcw2023.185
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Antimicrobial Activity of Stilbenes from

Yu, Qian / Sun, Luyao / Peng, Fu / Sun, Chen / Xiong, Fang / Sun, Meiji / Liu, Juan / Peng, Cheng / Zhou, Qinmei

Microorganisms

2023 Volume 11, Issue 12

Abstract: The abnormal proliferation ... ...

Abstract	The abnormal proliferation of
Language	English
Publishing date	2023-12-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms11122958
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Article ; Online: RPL35A drives ovarian cancer progression by promoting the binding of YY1 to CTCF promoter.

Wu, Huijuan / Xia, Liangbin / Sun, Lu / Li, Dan / Liu, Xiangyu / Song, Hualin / Sheng, Jindong / Wang, Ke / Feng, Qinmei

Journal of cellular and molecular medicine

2024 Volume 28, Issue 6, Page(s) e18115

Abstract: Ovarian cancer is one of the most common gynaecological malignancies with poor prognosis and lack of effective treatment. The improvement of the situation of ovarian cancer urgently requires the exploration of its molecular mechanism to develop more ... ...

Abstract	Ovarian cancer is one of the most common gynaecological malignancies with poor prognosis and lack of effective treatment. The improvement of the situation of ovarian cancer urgently requires the exploration of its molecular mechanism to develop more effective molecular targeted drugs. In this study, the role of human ribosomal protein l35a (RPL35A) in ovarian cancer was explored in vitro and in vivo. Our data identified that RPL35A expression was abnormally elevated in ovarian cancer. Clinically, high expression of RPL35A predicted short survival and poor TNM staging in patients with ovarian cancer. Functionally, RPL35A knock down inhibited ovarian cancer cell proliferation and migration, enhanced apoptosis, while overexpression had the opposite effect. Mechanically, RPL35A promoted the direct binding of transcription factor YY1 to CTCF in ovarian cancer cells. Consistently, RPL35A regulated ovarian cancer progression depending on CTCF in vitro and in vivo. Furthermore, RPL35A affected the proliferation and apoptosis of ovarian cancer cells through PPAR signalling pathway. In conclusion, RPL35A drove ovarian cancer progression by promoting the binding of YY1 and CTCF promoter, and inhibiting this process may be an effective strategy for targeted therapy of this disease.
MeSH term(s)	Female ; Humans ; Apoptosis/genetics ; Cell Proliferation/genetics ; Genital Neoplasms, Female ; Ovarian Neoplasms/genetics ; Ribosomal Proteins/genetics ; Ribosomal Proteins/metabolism ; YY1 Transcription Factor/genetics ; YY1 Transcription Factor/metabolism ; CCCTC-Binding Factor/genetics
Chemical Substances	Ribosomal Proteins ; RPL35A protein, human ; YY1 protein, human ; YY1 Transcription Factor ; CTCF protein, human ; CCCTC-Binding Factor
Language	English
Publishing date	2024-03-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2074559-X
ISSN	1582-4934 ; 1582-4934 ; 1582-1838
ISSN (online)	1582-4934
ISSN	1582-4934 ; 1582-1838
DOI	10.1111/jcmm.18115
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Zs.A 5752: Show issues

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ab Jg. 2022: Lesesaal (EG)

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Article: Development and field evaluation of a novel sugar bait device for controlling residential vector mosquitoes in Zhejiang Province, China.

Wu, Yuyan / Zhang, Chuan / Feng, Wei / Fu, Sanjun / Dong, Weibo / Wang, Jinna / Liu, Qinmei / Li, Tianqi / Luo, Mingyu / Gong, Zhenyu

Frontiers in veterinary science

2024 Volume 11, Page(s) 1364740

Abstract: Background: Mosquito-borne diseases pose serious public health threats in Zhejiang Province, China, and vector control is believed to be the primary method for reducing transmission. Due to severe resistance problems, effective and sustainable methods ... ...

Abstract	Background: Mosquito-borne diseases pose serious public health threats in Zhejiang Province, China, and vector control is believed to be the primary method for reducing transmission. Due to severe resistance problems, effective and sustainable methods without chemical insecticides are urgently required to control mosquito vectors. Attractive toxic sugar baits (ATSB) are newly developed methods to control mosquitoes in recent decades with the core element sugar bait, which was invented according to the sugar-feeding behavior of mosquitoes. In this study, we developed a Novel Sugar Bait Device (NSBD) trap by combining sugar bait and physical adhesive capture technology. The study aimed to evaluate the effect of the NSBD trap on controlling mosquitoes in residential environments and to identify the optimal sugar solution concentration in the sugar bait of the NSBD for real use. Methods: Four residential villages in Ningbo City with similar geographic environments and mosquito densities were selected for field trials in 2022. One village (site 1) was designated as the control group, and three villages (sites 2-4) served as the test groups to assess the effectiveness of NSBD traps with different sugar solution concentrations (6, 8, and 10%) in the sugar bait. Larval and adult mosquito densities were monitored monthly before and semi-monthly after the trials using the CDC light trap and larval pipette method. Results: Before the trials, we monitored mosquito density for 3 months to confirm the baseline mosquito density among the four sites, and no statistical differences in adult and larval mosquitoes were found (adult, Conclusion: NSBD traps effectively controlled mosquitoes in residential environments during field trials. Without the use of insecticides, this may be a promising choice for mosquito vector control to prevent mosquito-borne diseases.
Language	English
Publishing date	2024-03-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2834243-4
ISSN	2297-1769
ISSN	2297-1769
DOI	10.3389/fvets.2024.1364740
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Article ; Online: OsJRL40

Gao, Qinmei / Yin, Xiaolin / Wang, Feng / Hu, Shuchang / Liu, Weihao / Chen, Liangbi / Dai, Xiaojun / Liang, Manzhong

International journal of molecular sciences

2023 Volume 24, Issue 8

Abstract: High salinity is a major stress factor affecting the quality and productivity of rice ( ...

Abstract	High salinity is a major stress factor affecting the quality and productivity of rice (
MeSH term(s)	Salt Tolerance/genetics ; Oryza/metabolism ; Lectins/genetics ; Lectins/metabolism ; Plant Breeding ; Salt Stress/genetics ; Ions/metabolism ; Gene Expression Regulation, Plant ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Salinity
Chemical Substances	jacalin ; Lectins ; Ions ; Plant Proteins
Language	English
Publishing date	2023-04-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24087441
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Article ; Online: An Optimized Two-Dimensional Quantitative Nuclear Magnetic Resonance Strategy for the Rapid Quantitation of Diester-Type C

Lin, Qiao / Meng, Chunwang / Liu, Jie / Liu, Fei / Zhou, Qinmei / Liu, Juan / Peng, Cheng / Xiong, Liang

Analytical chemistry

2023 Volume 95, Issue 22, Page(s) 8452–8460

Abstract: With the development of nuclear magnetic resonance (NMR) spectrometers and probes, two-dimensional quantitative nuclear magnetic resonance (2D qNMR) technology with a high signal resolution and great application potential has become increasingly ... ...

Abstract	With the development of nuclear magnetic resonance (NMR) spectrometers and probes, two-dimensional quantitative nuclear magnetic resonance (2D qNMR) technology with a high signal resolution and great application potential has become increasingly accessible for the quantitation of complex mixtures. However, the requirement that the relaxation recovery time be equal to at least five times
MeSH term(s)	Aconitum/chemistry ; Reproducibility of Results ; Alkaloids/analysis ; Diterpenes/analysis ; Magnetic Resonance Spectroscopy ; Plant Roots/chemistry ; Molecular Structure
Chemical Substances	Alkaloids ; Diterpenes
Language	English
Publishing date	2023-05-20
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1508-8
ISSN	1520-6882 ; 0003-2700
ISSN (online)	1520-6882
ISSN	0003-2700
DOI	10.1021/acs.analchem.2c05109
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Zs.A 4033: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: LncRNA NR_003508 Suppresses Mycobacterium tuberculosis -Induced Programmed Necrosis via Sponging miR-346-3p to Regulate RIPK1

Li Liu / Zhirui Yu / Qinmei Ma / Jialin Yu / Zhaoqian Gong / Guangcun Deng / Xiaoling Wu

International Journal of Molecular Sciences, Vol 24, Iss 8016, p

2023 Volume 8016

Abstract: Emerging evidence suggests that long non-coding RNAs (LncRNAs) are involved in Mtb-induced programmed necrosis. Among these LncRNAs, LncRNA NR_003508 is associated with LPS-induced acute respiratory distress syndrome. However, whether LncRNA NR_003508 ... ...

Abstract	Emerging evidence suggests that long non-coding RNAs (LncRNAs) are involved in Mtb-induced programmed necrosis. Among these LncRNAs, LncRNA NR_003508 is associated with LPS-induced acute respiratory distress syndrome. However, whether LncRNA NR_003508 contributes to Mtb-induced programmed necrosis remains undocumented. Firstly, the expression of LncRNA NR_003508 was determined using RT-qPCR and FISH. The protein expression of RIPK1, p-RIPK1, RIPK3, p-RIPK3, MLKL, and p-MLKL was measured by Western blot in RAW264.7 and mouse lung tissues. Furthermore, luciferase reporter assays and bioinformatics were used to predict specific miRNA (miR-346-3p) and mRNA (RIPK1) regulated by LncRNA NR_003508. In addition, RT-qPCR was used to detect the RIPK1 expression in TB patients and healthy peripheral blood. The flow cytometry assay was performed to detect cell necrosis rates. Here we show that BCG infection-induced cell necrosis and increased LncRNA NR_003508 expression. si-NR_003508 inhibited BCG/H37Rv-induced programmed necrosis in vitro or in vivo. Functionally, LncRNA NR_003508 has been verified as a ceRNA for absorbing miR-346-3p, which targets RIPK1. Moreover, RIPK1 expression was elevated in the peripheral blood of TB patients compared with healthy people. Knockdown of LncRNA NR_003508 or miR-346-3p overexpression suppresses cell necrosis rate and ROS accumulation in RAW264.7 cells. In conclusion, LncRNA NR_003508 functions as a positive regulator of Mtb-induced programmed necrosis via sponging miR-346-3p to regulate RIPK1. Our findings may provide a promising therapeutic target for tuberculosis.
Keywords	LncRNA NR_003508 ; programmed necrosis ; Mycobacterium tuberculosis ; miR-346-3p ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	616
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Retraction notice to "Kuntai capsule attenuates premature ovarian failure through the PI3K/AKT/mTOR pathway" [J. Ethnopharmacol. 239 (2019) 111885].

Zhang, Han / Qin, Fenfen / Liu, Anlong / Sun, Qinmei / Wang, Qisheng / Li, Qian / Lu, Shengfeng / Zhang, Dong / Lu, Zhigang

Journal of ethnopharmacology

2022 Volume 289, Page(s) 115091

Language	English
Publishing date	2022-02-09
Publishing country	Ireland
Document type	Journal Article ; Retraction of Publication
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2022.115091
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Zs.A 1494: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: From SARS to the Omicron variant of COVID-19: China's policy adjustments and changes to prevent and control infectious diseases.

Luo, Mingyu / Liu, Qinmei / Wang, Jinna / Gong, Zhenyu

Bioscience trends

2021 Volume 15, Issue 6, Page(s) 418–423

Abstract: The COVID-19 pandemic has been the biggest public health crisis in a century. Since it was initially reported in 2019, the duration and intensity of its impacts are still in serious question around the world, and it is about to enter its third year. The ... ...

Abstract	The COVID-19 pandemic has been the biggest public health crisis in a century. Since it was initially reported in 2019, the duration and intensity of its impacts are still in serious question around the world, and it is about to enter its third year. The first public health revolution failed to achieve its ultimate targets, as previously contained infectious diseases seem to have returned, and new infectious diseases continue to emerge. The prevention and control of infectious diseases is still a public health priority worldwide. After SARS, China adjusted a series of its infectious disease policies. In order to ensure the effectiveness and implementation of prevention and control interventions, the government should integrate the concept of public health. Perhaps we need a global public health system at the government level to fight the potential threat of infectious disease. This system could include multifaceted strategies, not just specific prevention and control interventions, and it could also be a comprehensive system to ensure unimpeded communication and cooperation as well as sustainable development.
MeSH term(s)	COVID-19 ; China ; Communicable Diseases/epidemiology ; Humans ; Pandemics ; Policy ; SARS-CoV-2
Language	English
Publishing date	2021-12-18
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2543899-2
ISSN	1881-7823 ; 1881-7823
ISSN (online)	1881-7823
ISSN	1881-7823
DOI	10.5582/bst.2021.01535
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Article ; Online: LncRNA NR_003508 Suppresses

Liu, Li / Yu, Zhirui / Ma, Qinmei / Yu, Jialin / Gong, Zhaoqian / Deng, Guangcun / Wu, Xiaoling

International journal of molecular sciences

2023 Volume 24, Issue 9

Abstract	Emerging evidence suggests that long non-coding RNAs (LncRNAs) are involved in Mtb-induced programmed necrosis. Among these LncRNAs, LncRNA NR_003508 is associated with LPS-induced acute respiratory distress syndrome. However, whether LncRNA NR_003508 contributes to Mtb-induced programmed necrosis remains undocumented. Firstly, the expression of LncRNA NR_003508 was determined using RT-qPCR and FISH. The protein expression of RIPK1, p-RIPK1, RIPK3, p-RIPK3, MLKL, and p-MLKL was measured by Western blot in RAW264.7 and mouse lung tissues. Furthermore, luciferase reporter assays and bioinformatics were used to predict specific miRNA (miR-346-3p) and mRNA (RIPK1) regulated by LncRNA NR_003508. In addition, RT-qPCR was used to detect the RIPK1 expression in TB patients and healthy peripheral blood. The flow cytometry assay was performed to detect cell necrosis rates. Here we show that BCG infection-induced cell necrosis and increased LncRNA NR_003508 expression. si-NR_003508 inhibited BCG/H37Rv-induced programmed necrosis in vitro or in vivo. Functionally, LncRNA NR_003508 has been verified as a ceRNA for absorbing miR-346-3p, which targets RIPK1. Moreover, RIPK1 expression was elevated in the peripheral blood of TB patients compared with healthy people. Knockdown of LncRNA NR_003508 or miR-346-3p overexpression suppresses cell necrosis rate and ROS accumulation in RAW264.7 cells. In conclusion, LncRNA NR_003508 functions as a positive regulator of Mtb-induced programmed necrosis via sponging miR-346-3p to regulate RIPK1. Our findings may provide a promising therapeutic target for tuberculosis.
MeSH term(s)	Animals ; Mice ; BCG Vaccine ; Cell Proliferation/genetics ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Mycobacterium tuberculosis/metabolism ; Necrosis/genetics ; Receptor-Interacting Protein Serine-Threonine Kinases/genetics ; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism
Chemical Substances	BCG Vaccine ; MicroRNAs ; Receptor-Interacting Protein Serine-Threonine Kinases (EC 2.7.11.1) ; Ripk1 protein, mouse (EC 2.7.11.1) ; RNA, Long Noncoding ; MIRN346 microRNA, mouse
Language	English
Publishing date	2023-04-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24098016
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