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  1. Article: Prof. David Moher: Guidelines for Reporting Health Research (A User's Manual).

    Du, Kathy J / Li, Grace S / Zhang, Kaiping / Lin, Yao / Yang, Fanghui / Moher, David

    Annals of translational medicine

    2022  Volume 10, Issue 17, Page(s) 944

    Language English
    Publishing date 2022-09-22
    Publishing country China
    Document type Editorial
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm-2022-24
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lessons from the COVID-19 pandemic and recent developments on the communication of clinical trials, publishing practices, and research integrity: in conversation with Dr. David Moher.

    Lawson, Daeria O / Wang, Michael K / Kim, Kevin / Eikelboom, Rachel / Rodrigues, Myanca / Trapsa, Daniela / Thabane, Lehana / Moher, David

    Trials

    2022  Volume 23, Issue 1, Page(s) 671

    Abstract: ... epidemiologists-in-training. Dr. David Moher, a recognized expert on the science of research reporting and one ... guidelines on trials and issues with the use of CONSORT as a measure of quality. Dr. Moher also addresses how ... To combat this, Dr. Moher believes open science and training initiatives led by institutions can foster ...

    Abstract Background: The torrent of research during the coronavirus (COVID-19) pandemic has exposed the persistent challenges with reporting trials, open science practices, and scholarship in academia. These real-world examples provide unique learning opportunities for research methodologists and clinical epidemiologists-in-training. Dr. David Moher, a recognized expert on the science of research reporting and one of the founders of the Consolidated Standards of Reporting Trials (CONSORT) statement, was a guest speaker for the 2021 Hooker Distinguished Visiting Professor Lecture series at McMaster University and shared his insights about these issues.
    Main text: This paper covers a discussion on the influence of reporting guidelines on trials and issues with the use of CONSORT as a measure of quality. Dr. Moher also addresses how the overwhelming body of COVID-19 research reflects the "publish or perish" paradigm in academia and why improvement in the reporting of trials requires policy initiatives from research institutions and funding agencies. We also discuss the rise of publication bias and other questionable reporting practices. To combat this, Dr. Moher believes open science and training initiatives led by institutions can foster research integrity, including the trustworthiness of researchers, institutions, and journals, as well as counter threats posed by predatory journals. He highlights how metrics like journal impact factor and quantity of publications also harm research integrity. Dr. Moher also discussed the importance of meta-science, the study of how research is carried out, which can help to evaluate audit and feedback systems and their effect on open science practices.
    Conclusion: Dr. Moher advocates for policy to further improve the reporting of trials and health research. The COVID-19 pandemic has exposed how a lack of open science practices and flawed systems incentivizing researchers to publish can harm research integrity. There is a need for a culture shift in assessing careers and "productivity" in academia, and this requires collaborative top-down and bottom-up approaches.
    MeSH term(s) COVID-19 ; Communication ; Humans ; Pandemics ; Publishing ; Research Personnel
    Language English
    Publishing date 2022-08-17
    Publishing country England
    Document type Letter
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-022-06624-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: David Moher, MSc The CONSORT Guidelines: improving the quality of research. Consolidated Standards of Reporting Trials. Interview by Bonnie Horrigan.

    Moher, David

    Alternative therapies in health and medicine

    2002  Volume 8, Issue 3, Page(s) 103–108

    MeSH term(s) Clinical Trials as Topic/standards ; Complementary Therapies/standards ; Evidence-Based Medicine ; Guidelines as Topic ; Humans ; Ontario ; Quality Control ; Randomized Controlled Trials as Topic/standards ; Research Design/standards ; Research Support as Topic
    Language English
    Publishing date 2002-05
    Publishing country United States
    Document type Interview
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4504: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Increasing our return on investment in science: Start with better behavior.

    Moher, David

    Journal of sport and health science

    2023  Volume 12, Issue 3, Page(s) 281–283

    Language English
    Publishing date 2023-02-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 2673028-5
    ISSN 2213-2961 ; 2095-2546
    ISSN (online) 2213-2961
    ISSN 2095-2546
    DOI 10.1016/j.jshs.2023.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Implementing Incentives and Rewards to Improve the Research Ecosystem.

    Moher, David

    JAMA network open

    2021  Volume 4, Issue 11, Page(s) e2138622

    MeSH term(s) Ecosystem ; Humans ; Motivation ; Reward
    Language English
    Publishing date 2021-11-01
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.38622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: COVID-19 and the research scholarship ecosystem: help!

    Moher, David

    Journal of clinical epidemiology

    2021  Volume 137, Page(s) 133–136

    Abstract: Objectives: Data sharing practices remain elusive in biomedicine. The COVID-19 pandemic has highlighted the problems associated with the lack of data sharing. The objective of this article is to draw attention to the problem and possible ways to address ...

    Abstract Objectives: Data sharing practices remain elusive in biomedicine. The COVID-19 pandemic has highlighted the problems associated with the lack of data sharing. The objective of this article is to draw attention to the problem and possible ways to address it.
    Study design and setting: This article examines some of the current open access and data sharing practices at biomedical journals and funders. In the context of COVID-19 the consequences of these practices is also examined.
    Results: Despite the best of intentions on the part of funders and journals, COVID-19 biomedical research is not open. Academic institutions need to incentivize and reward data sharing practices as part of researcher assessment. Journals and funders need to implement strong polices to ensure that data sharing becomes a reality. Patients support sharing of their data.
    Conclusion: Biomedical journals, funders and academic institutions should act to require stronger adherence to data sharing policies.
    MeSH term(s) Biomedical Research ; COVID-19/epidemiology ; Humans ; Information Dissemination ; Open Access Publishing ; Periodicals as Topic
    Language English
    Publishing date 2021-04-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2021.03.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.206: Show issues Location:
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  7. Article ; Online: Key concepts in clinical epidemiology: Research Integrity definitions and challenges.

    Armond, Anna Catharina V / Cobey, Kelly D / Moher, David

    Journal of clinical epidemiology

    2024  , Page(s) 111367

    Abstract: Research integrity is guided by a set of principles to ensure research reliability, and rigor. It serves as a pillar to uphold society's trust in science and foster scientific progress. However, over the past two decades, a surge in research integrity ... ...

    Abstract Research integrity is guided by a set of principles to ensure research reliability, and rigor. It serves as a pillar to uphold society's trust in science and foster scientific progress. However, over the past two decades, a surge in research integrity concerns, including fraudulent research, reproducibility challenges, and questionable practices, has raised critical questions about the reliability of scientific outputs, particularly in biomedical research. In the biomedical sciences, any breaches in research integrity could potentially lead to a domino effect impacting patient care, medical interventions, and the broader implementation of healthcare policies. Addressing these breaches requires measures such as rigorous research methods, transparent reporting, and changing the research culture. Institutional support through clear guidelines, robust training, and mentorship is crucial to fostering a culture of research integrity. However, structural and institutional factors, including research incentives and recognition systems, play an important role in research behavior. Therefore, promoting research integrity demands a collective effort from all stakeholders to maintain public trust in the scientific community and ensure the reliability of science. Here we discuss some definitions and principles, the implications for biomedical sciences, and propose actionable steps to foster research integrity.
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2024.111367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.206: Show issues Location:
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  8. Article ; Online: The reporting quality and spin of randomized controlled trials of endometriosis pain: Methodological study based on CONSORT extension on abstracts.

    Shirafkan, Hoda / Moher, David / Mirabi, Parvaneh

    PloS one

    2024  Volume 19, Issue 5, Page(s) e0302108

    Abstract: Objective: To assess the reporting quality of published RCT abstracts regarding patients with endometriosis pelvic pain and investigate the prevalence and characteristics of spin in these abstracts.: Methods: PubMed and Scopus were searched for RCT ... ...

    Abstract Objective: To assess the reporting quality of published RCT abstracts regarding patients with endometriosis pelvic pain and investigate the prevalence and characteristics of spin in these abstracts.
    Methods: PubMed and Scopus were searched for RCT abstracts addressing endometriosis pelvic pain published from January 1st, 2010 to December 1st, 2023.The reporting quality of RCT abstracts was assessed using the CONSORT statement for abstracts. Additionally, spin was evaluated in the results and conclusions section of the abstracts, defined as the misleading reporting of study findings to emphasize the perceived benefits of an intervention or to confound readers from statistically non-significant results. Assessing factors affecting the reporting quality and spin existence, linear and logistic regression was used, respectively.
    Results: A total of 47 RCT abstracts were included. Out of 16 checklist items, only three items including objective, intervention and conclusions were sufficiently reported in the most abstracts (more than 95%), and none of the abstracts presented precise data as required by the CONSORT-A guidelines. In the reporting quality of material and method section, trial design, type of randomization, the generation of random allocation sequences, the allocation concealment and blinding were most items identified that were suboptimal. The total score for the quality varied between 5 and 15 (mean: 9.59, SD: 3.03, median: 9, IQR: 5). Word count (beta = 0.015, p-value = 0.005) and publishing in open-accessed journals (beta = 2.023, p-value = 0.023) were the significant factors that affecting the reporting quality. Evaluating spin within each included paper, we found that 18 (51.43%) papers had statistically non-significant results. From these studies, 12 (66.66%) had spin in both results and conclusion sections. Furthermore, the spin intensity increased during 2010-2023 and 38.29% of abstracts had spin in both results and conclusion sections.
    Conclusion: Overall poor adherence to CONSORT-A was observed, with spin detected in several RCTs featuring non-significant primary endpoints in obstetrics and gynecology literature.
    MeSH term(s) Humans ; Female ; Randomized Controlled Trials as Topic/standards ; Endometriosis ; Research Design/standards ; Pelvic Pain ; Abstracting and Indexing/standards
    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0302108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The White House’s march towards open science

    David Moher / Kelly D. Cobey

    FACETS, Vol 8, Iss , Pp 1-

    implications for Canada

    2023  Volume 4

    Keywords Education ; L ; Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Canadian Science Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article ; Online: Reporting guidelines: doing better for readers.

    Moher, David

    BMC medicine

    2018  Volume 16, Issue 1, Page(s) 233

    Abstract: There is clear guidance on the responsibilities of editors to ensure that the research they publish is of the highest possible quality. Poor reporting is unethical and directly impacts patient care. Reporting guidelines are a relatively recent ... ...

    Abstract There is clear guidance on the responsibilities of editors to ensure that the research they publish is of the highest possible quality. Poor reporting is unethical and directly impacts patient care. Reporting guidelines are a relatively recent development to help improve the accuracy, clarity, and transparency of biomedical publications. They have caught on, with hundreds of reporting guidelines now available. Some journals endorse reporting guidelines while a smaller number have used various approaches to implement them. Yet challenges remain - biomedical research is still not optimally reported despite the abundance of reporting guidelines. Electronic algorithms are now being developed to facilitate the choice of correct reporting guideline(s), while other tools are being integrated into journal editorial management processes. Universities need to consider whether it is responsible to advance careers of faculty based on poorly reported research which is of little societal value. If journals embraced auditing of the quality of articles they publish this would give them and their readers essential feedback from which to improve their product.
    MeSH term(s) Biomedical Research/standards ; Humans ; Publications/standards ; Publishing/standards ; Research Report/standards
    Language English
    Publishing date 2018-12-14
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ISSN 1741-7015
    ISSN (online) 1741-7015
    DOI 10.1186/s12916-018-1226-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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