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  1. Article ; Online: Comment on: "Efficacy and Safety of Saroglitazar in Patients with Cardiometabolic Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials".

    Dutta, Deep / Mohindra, Ritin / Misra, Anoop

    Clinical drug investigation

    2023  Volume 43, Issue 2, Page(s) 147–148

    MeSH term(s) Humans ; Randomized Controlled Trials as Topic ; Pyrroles ; Phenylpropionates ; Cardiovascular Diseases/drug therapy
    Chemical Substances saroglitazar (E0YMX3S4JD) ; Pyrroles ; Phenylpropionates
    Language English
    Publishing date 2023-01-13
    Publishing country New Zealand
    Document type Meta-Analysis ; Systematic Review ; Letter ; Comment
    ZDB-ID 1220136-4
    ISSN 1179-1918 ; 0114-2402 ; 1173-2563
    ISSN (online) 1179-1918
    ISSN 0114-2402 ; 1173-2563
    DOI 10.1007/s40261-022-01245-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2807: Show issues Location:
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  2. Article: Journal Summary: Syndromic Molecular Point-of-Care Testing for Gastrointestinal Pathogens versus Routine Microbiological Testing for Gastroenteritis

    Mohindra, Ritin / Saini, Manpreet / Pahil, Sapna

    Journal of Gastrointestinal Infections

    2023  Volume 13, Issue 02, Page(s) 92–94

    Language English
    Publishing date 2023-07-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 2583-844X
    ISSN (online) 2583-844X
    DOI 10.1055/s-0043-1777088
    Database Thieme publisher's database

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  3. Article ; Online: Some reflections on vaccine research ethics during COVID-19 pandemic.

    Gamad, Nanda / Shafiq, Nusrat / Mohindra, Ritin / Bhalla, Ashish / Malhotra, Samir

    Postgraduate medical journal

    2022  Volume 98, Issue e2, Page(s) e84–e85

    MeSH term(s) COVID-19/prevention & control ; Ethics, Research ; Humans ; Pandemics/prevention & control ; SARS-CoV-2 ; Vaccines
    Chemical Substances Vaccines
    Language English
    Publishing date 2022-02-25
    Publishing country England
    Document type Letter
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1136/postgradmedj-2020-139145
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    Ua VI Zs.340: Show issues Location:
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  4. Article ; Online: Leprosy, steroids, and diabetes: a recipe for mucormycosis?

    Jain, Sejal / Mohindra, Ritin / Chatterjee, Debajyoti / Rudramurthy, Shivaprakash / Vyas, Sameer / Dogra, Sunil / Narang, Tarun

    International journal of dermatology

    2023  Volume 63, Issue 1, Page(s) e16–e18

    MeSH term(s) Humans ; Mucormycosis/diagnosis ; Mucormycosis/drug therapy ; Diabetes Mellitus ; Leprosy/complications ; Leprosy/diagnosis ; Leprosy/drug therapy ; Steroids/therapeutic use
    Chemical Substances Steroids
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.16904
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  5. Article ; Online: Limbic system symptoms of rabies infection.

    Mohindra, Ritin / Madhav, Mohata / Suri, Vikas / Divyashree, Krishna

    BMJ case reports

    2022  Volume 15, Issue 7

    Abstract: Rabies is a fatal aggressive disease of the nervous system which predominantly causes motor and autonomic dysfunction. Limbic system involvement has been reported rarely, with limited data on its prevalence. The diagnosis becomes challenging when a ... ...

    Abstract Rabies is a fatal aggressive disease of the nervous system which predominantly causes motor and autonomic dysfunction. Limbic system involvement has been reported rarely, with limited data on its prevalence. The diagnosis becomes challenging when a patient presents with limbic system involvement in the absence of a clear history of an animal bite. We herein illustrate a case of a young man who presented with recurrent episodes of inappropriate ejaculation. He eventually developed hydrophobia and aerophobia, leading to a diagnosis of rabies. This case emphasises the importance of considering the possibility of rabies encephalitis when a patient presents with symptoms of limbic system involvement since early diagnosis helps in instituting appropriate public health measures and reducing exposure to infection. Furthermore, high-quality intensive care with supportive management is the mainstay of therapy in such patients until we have novel and effective antiviral drugs for rabies treatment.
    MeSH term(s) Animals ; Bites and Stings ; Humans ; Limbic System ; Male ; Phobic Disorders ; Rabies/diagnosis ; Rabies/epidemiology ; Rabies Vaccines ; Rabies virus
    Chemical Substances Rabies Vaccines
    Language English
    Publishing date 2022-07-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2022-249965
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Vaccine Breakthrough Infections with SARS-CoV-2 Variants.

    Rana, Kirtan / Mohindra, Ritin / Pinnaka, Lakshmi

    The New England journal of medicine

    2021  Volume 385, Issue 2, Page(s) e7

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Communicable Diseases ; Humans ; SARS-CoV-2
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-06-02
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2107808
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    Ua VI Zs.34: Show issues Location:
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  7. Article ; Online: Safety and efficacy of once weekly dipeptidyl-peptidase-4 inhibitor trelagliptin in type-2 diabetes: A meta-analysis.

    Dutta, Deep / Mohindra, Ritin / Surana, Vineet / Sharma, Meha

    Diabetes & metabolic syndrome

    2022  Volume 16, Issue 4, Page(s) 102469

    Abstract: Background & aims: Pooled systematic analysis of safety and efficacy data of trelagliptin in type-2 diabetes (T2DM) is lacking. We undertook this meta-analysis to address this issue.: Methods: Electronic databases were searched for RCTs involving ... ...

    Abstract Background & aims: Pooled systematic analysis of safety and efficacy data of trelagliptin in type-2 diabetes (T2DM) is lacking. We undertook this meta-analysis to address this issue.
    Methods: Electronic databases were searched for RCTs involving people with T2DM receiving trelagliptin in study arm, and placebo/active comparator in control arm. Primary outcome was to evaluate changes in HbA1c. Secondary outcomes were to evaluate alterations in pre and post-meal glucose levels, glycaemic targets, lipid parameters and adverse events.
    Results: From initially screened 63 articles, data from 6 RCTs involving 981 patients was analysed [3 in active control group (ACG) defined as having alogliptin, sitagliptin, linagliptin, teneligliptin, anagliptin or vildagliptin as active comparator; 2 in passive control group (PCG) defined as having placebo as controls; 1 study had both ACG and PCG]. HbA1c reduction by trelagliptin was comparable to ACG [MD 0.06% (95% CI: -0.03 - 0.16); P = 0.20; I
    Conclusion: Once weekly trelagliptin has good glycaemic efficacy and well tolerated in people with T2DM.
    MeSH term(s) Blood Glucose ; Diabetes Mellitus, Type 2/drug therapy ; Dipeptidyl-Peptidase IV Inhibitors/adverse effects ; Humans ; Hypoglycemic Agents/adverse effects ; Treatment Outcome ; Uracil/analogs & derivatives
    Chemical Substances Blood Glucose ; Dipeptidyl-Peptidase IV Inhibitors ; Hypoglycemic Agents ; Uracil (56HH86ZVCT) ; trelagliptin (Q836OWG55H)
    Language English
    Publishing date 2022-03-21
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 2273766-2
    ISSN 1878-0334 ; 1871-4021
    ISSN (online) 1878-0334
    ISSN 1871-4021
    DOI 10.1016/j.dsx.2022.102469
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  8. Article ; Online: Performance of Fast-Acting Aspart Insulin as Compared to Aspart Insulin in Insulin Pump for Managing Type 1 Diabetes Mellitus: A Meta-Analysis.

    Dutta, Deep / Mohindra, Ritin / Mahajan, Kunal / Sharma, Meha

    Diabetes & metabolism journal

    2022  Volume 47, Issue 1, Page(s) 72–81

    Abstract: Background: No meta-analysis has analysed efficacy and safety of fast-acting aspart insulin (FIAsp) with insulin pump in type 1 diabetes mellitus (T1DM).: Methods: Electronic databases were searched for randomised controlled trials (RCTs) involving ... ...

    Abstract Background: No meta-analysis has analysed efficacy and safety of fast-acting aspart insulin (FIAsp) with insulin pump in type 1 diabetes mellitus (T1DM).
    Methods: Electronic databases were searched for randomised controlled trials (RCTs) involving T1DM patients on insulin pump receiving FIAsp in intervention arm, and placebo/active comparator insulin in control arm. Primary outcome was to evaluate changes in 1- and 2-hour post-prandial glucose (1hPPG and 2hPPG). Secondary outcomes were to evaluate alterations in percentage time with blood glucose <3.9 mmol/L (hypoglycaemia), time in range (TIR) blood glucose 3.9 to 10 mmol/L, insulin requirements and adverse events.
    Results: Data from four RCTs involving 640 patients was analysed. FIAsp use in insulin pump was associated with significantly greater lowering of 1hPPG (mean difference [MD], -1.35 mmol/L; 95% confidence interval [CI], -1.72 to -0.98; P<0.01; I2=63%) and 2hPPG (MD, -1.19 mmol/L; 95% CI, -1.38 to -1.00; P<0.01; I2=0%) as compared to controls. TIR was comparable among groups (MD, 1.06%; 95% CI, -3.84 to 5.96; P=0.67; I2=70%). Duration of blood glucose <3.9 mmol/L was lower in FIAsp group, approaching significance (MD, -0.91%; 95% CI, -1.84 to 0.03; P=0.06; I2=0%). Total hypoglycaemic episodes (risk ratio [RR], 1.35; 95% CI, 0.55 to 3.31; P=0.51; I2=0%), severe hypoglycaemia (RR, 2.26; 95% CI, 0.77 to 6.66; P=0.14), infusion site reactions (RR, 1.35; 95% CI, 0.63 to 2.93; P=0.77; I2=0%), and treatment-emergent adverse events (RR, 1.13; 95% CI, 0.80 to 1.60; P=0.50; I2=0%) were comparable.
    Conclusion: FIAsp use in insulin pump is associated with better post-prandial glycaemic control with no increased hypoglycaemia or glycaemic variability.
    MeSH term(s) Humans ; Blood Glucose ; Diabetes Mellitus, Type 1/drug therapy ; Hypoglycemia/chemically induced ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Insulin Aspart/therapeutic use
    Chemical Substances Blood Glucose ; Hypoglycemic Agents ; Insulin ; Insulin Aspart (D933668QVX)
    Language English
    Publishing date 2022-06-24
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2602402-0
    ISSN 2233-6087 ; 2233-6087
    ISSN (online) 2233-6087
    ISSN 2233-6087
    DOI 10.4093/dmj.2022.0035
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  9. Article ; Online: Neisseria mucosa: A not so Benign Culprit of urinary tract infection: A case report.

    Yadav, Sukriti / Pahil, Sapna / Kumar, Mani Bhushan / Mohindra, Ritin / Mohan, Balvinder / Taneja, Neelam

    Indian journal of medical microbiology

    2023  Volume 47, Page(s) 100514

    Abstract: Neisseria mucosa is saprophytic human commensal but reported as a causative agent in a couple of urinary tract infections [UTI] in susceptible individuals. In the present case, a young girl with long standing neurological problems presented with bladder ... ...

    Abstract Neisseria mucosa is saprophytic human commensal but reported as a causative agent in a couple of urinary tract infections [UTI] in susceptible individuals. In the present case, a young girl with long standing neurological problems presented with bladder outlet obstruction and fever. Her urine culture yielded Neisseria mucosa which was susceptible to broad spectrum penicillins, aminoglycosides, cephalosporins, ciprofloxacin, and azithromycin. She recovered with suitable dosage of amoxicillin clavulanic acid and was discharged. Isolation of N. mucosa here becomes clinically significant as this girl had various ureteric and lower limb weaknesses in past and was symptomatic for UTI with this infection.
    MeSH term(s) Humans ; Female ; Neisseria mucosa ; Urinary Tract Infections/diagnosis ; Urinary Tract Infections/drug therapy ; Anti-Bacterial Agents/therapeutic use ; Penicillins ; Cephalosporins
    Chemical Substances Anti-Bacterial Agents ; Penicillins ; Cephalosporins
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.1016/j.ijmmb.2023.100514
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  10. Article ; Online: Poor oral health may prolong COVID-19 illness.

    Gupta, Shipra / Sorsa, Timo / Brandt, Ella / Räisänen, Ismo T / Mohindra, Ritin / Goyal, Kapil

    Journal of translational medicine

    2022  Volume 20, Issue 1, Page(s) 113

    MeSH term(s) COVID-19 ; Humans ; Oral Health ; SARS-CoV-2
    Language English
    Publishing date 2022-03-07
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2118570-0
    ISSN 1479-5876 ; 1479-5876
    ISSN (online) 1479-5876
    ISSN 1479-5876
    DOI 10.1186/s12967-022-03310-0
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