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  1. Article ; Online: COMPARACIÓN DE LAS ECUACIONES DE COCKCROFT-GAULT Y MDRD CON LA FÓRMULA HABITUAL PARA LA ESTIMACIÓN DEL FILTRADO GLOMERULAR EN PACIENTES CON ENFERMEDAD RENAL CRÓNICA PROCEDENTES DEL HOSPITAL UNIVERSITARIO “ANTONIO PATRICIO DE ALCALÁ”, CUMANÁ, ESTADO SUCRE I COMPARISON OF EQUATIONS OF COCKCROFT - GAULT AND MDRD WITH USUAL FORMULA FOR THE ESTIMATION OF GLOMERULAR FILTRATION IN PATIENTS WITH CHRONIC KIDNEY DISEASE FROM UNIVERSITY HOSPITAL “ANTONIO PATRICIO DE ALCALÁ”,CUMANÁ, SUCRE STATE

    Haidee Guarache / Oriana González / Luisa Rojas de Astudillo

    Saber , Vol 25, Iss 2, Pp 176-

    2018  Volume 184

    Abstract: ... in patients with chronic kidney disease in stages III and IV, from the University Hospital “Antonio Patricio ...

    Abstract With the objective of comparing the equations of Cockcroft - Gault (CG) and Modification of Diet in Renal Disease (MDRD) with the usual formula for the estimation of the glomerular filtration rate (IFG), in patients with chronic kidney disease in stages III and IV, from the University Hospital “Antonio Patricio de Alcalá”, Cumaná, Sucre State, the anthropometric variables were evaluated, as well as serum creatinine concentrations, in 60 patients of both sexes, aged between 18 to 84 years old. With these results it was obtained that CG presented the highest sensitivity (86.7%) and effectiveness (90%), while specificity was similar to both equations (CG and MDRD = 100.0%). Using the Person’s correlation coefficient, CG showed a greater correlation(r = 0.63) to estimate IFG than the equation of MDRD (r = 0.59). An analysis of variance (ANOVA) indicated that there are significant differences ( p < 0.0001) between CG and MDRD equations with respect to the age. The equation of CG has greater correlation with the usual formula to estimate IFG, resulting that the equation of CG is a reliable, economic, simple and applicable method in the clinical laboratorie
    Keywords Índice de filtración glomerular estimada ; creatinina ; enfermedad renal crónica ; Estimated glomerular filtration rate ; creatinine ; chronic kidney disease ; Science ; Q ; Social Sciences ; H
    Subject code 616
    Language Spanish
    Publishing date 2018-05-01T00:00:00Z
    Publisher Universidad de Oriente
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Online: Nurses bring primary health care to industrial workers / Patricio Rojas, Ruth Stark & Prisca Tembo

    Rojas, Patricio / Stark, Ruth / Tembo, Prisca

    1990  

    Keywords Nurse practitioners ; Occupational health services ; Botswana ; Nursing and Midwifery ; manpower
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Online: Des infirmières assurent des soins de santé primaires sur les lieux de travail / Patricio Rojas, Ruth Stark & Prisca Tembo

    Rojas, Patricio / Stark, Ruth / Tembo, Prisca

    1990  

    Keywords Nurse practitioners ; Occupational health services ; Botswana ; Nursing and Midwifery ; manpower
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online: La planificaci'on estratégica en el desarrollo de los servicios de salud en Chile / Hugo Salinas Portillo y Patricio Silva Rojas

    Salinas Portillo, Hugo / Silva Rojas, Patricio

    1992  

    Keywords Health manpower ; Planning techniques ; Chile ; Human Resources for Health
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Journal ; Article ; Online: La planificación estratégica en el desarrollo de los servicios de salud en Chile / Hugo Salinas Portillo y Patricio Silva Rojas

    Salinas Portillo, Hugo / Silva Rojas, Patricio

    1992  

    Keywords Health Workforce ; Planning Techniques ; Chile ; Human Resources for Health
    Document type Journal ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Book ; Online: Las enfermeras llevan la atenci'on primaria de salud a los lugares de trabajo / Patricio Rojas, Ruth Stark y Prisca Tembo

    Rojas, Patricio / Stark, Ruth / Tembo, Prisca

    1990  

    Keywords Nurse practitioners ; Occupational health services ; Botswana ; Nursing and Midwifery ; manpower
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: A general modeling framework for quantitative tracking, accurate prediction of ICU, and assessing vaccination for COVID-19 in Chile.

    Cumsille, Patricio / Rojas-Díaz, Oscar / Conca, Carlos

    Frontiers in public health

    2023  Volume 11, Page(s) 1111641

    Abstract: Background: One of the main lessons of the COVID-19 pandemic is that we must prepare to face another pandemic like it. Consequently, this article aims to develop a general framework consisting of epidemiological modeling and a practical identifiability ... ...

    Abstract Background: One of the main lessons of the COVID-19 pandemic is that we must prepare to face another pandemic like it. Consequently, this article aims to develop a general framework consisting of epidemiological modeling and a practical identifiability approach to assess combined vaccination and non-pharmaceutical intervention (NPI) strategies for the dynamics of any transmissible disease.
    Materials and methods: Epidemiological modeling of the present work relies on delay differential equations describing time variation and transitions between suitable compartments. The practical identifiability approach relies on parameter optimization, a parametric bootstrap technique, and data processing. We implemented a careful parameter optimization algorithm by searching for suitable initialization according to each processed dataset. In addition, we implemented a parametric bootstrap technique to accurately predict the ICU curve trend in the medium term and assess vaccination.
    Results: We show the framework's calibration capabilities for several processed COVID-19 datasets of different regions of Chile. We found a unique range of parameters that works well for every dataset and provides overall numerical stability and convergence for parameter optimization. Consequently, the framework produces outstanding results concerning quantitative tracking of COVID-19 dynamics. In addition, it allows us to accurately predict the ICU curve trend in the medium term and assess vaccination. Finally, it is reproducible since we provide open-source codes that consider parameter initialization standardized for every dataset.
    Conclusion: This work attempts to implement a holistic and general modeling framework for quantitative tracking of the dynamics of any transmissible disease, focusing on accurately predicting the ICU curve trend in the medium term and assessing vaccination. The scientific community could adapt it to evaluate the impact of combined vaccination and NPIs strategies for COVID-19 or any transmissible disease in any country and help visualize the potential effects of implemented plans by policymakers. In future work, we want to improve the computational cost of the parametric bootstrap technique or use another more efficient technique. The aim would be to reconstruct epidemiological curves to predict the combined NPIs and vaccination policies' impact on the ICU curve trend in real-time, providing scientific evidence to help anticipate policymakers' decisions.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; Pandemics ; Chile/epidemiology ; Communicable Diseases ; Intensive Care Units
    Language English
    Publishing date 2023-03-31
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1111641
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A general modeling framework for quantitative tracking, accurate prediction of ICU, and assessing vaccination for COVID-19 in Chile

    Patricio Cumsille / Oscar Rojas-Díaz / Carlos Conca

    Frontiers in Public Health, Vol

    2023  Volume 11

    Abstract: BackgroundOne of the main lessons of the COVID-19 pandemic is that we must prepare to face another pandemic like it. Consequently, this article aims to develop a general framework consisting of epidemiological modeling and a practical identifiability ... ...

    Abstract BackgroundOne of the main lessons of the COVID-19 pandemic is that we must prepare to face another pandemic like it. Consequently, this article aims to develop a general framework consisting of epidemiological modeling and a practical identifiability approach to assess combined vaccination and non-pharmaceutical intervention (NPI) strategies for the dynamics of any transmissible disease.Materials and methodsEpidemiological modeling of the present work relies on delay differential equations describing time variation and transitions between suitable compartments. The practical identifiability approach relies on parameter optimization, a parametric bootstrap technique, and data processing. We implemented a careful parameter optimization algorithm by searching for suitable initialization according to each processed dataset. In addition, we implemented a parametric bootstrap technique to accurately predict the ICU curve trend in the medium term and assess vaccination.ResultsWe show the framework's calibration capabilities for several processed COVID-19 datasets of different regions of Chile. We found a unique range of parameters that works well for every dataset and provides overall numerical stability and convergence for parameter optimization. Consequently, the framework produces outstanding results concerning quantitative tracking of COVID-19 dynamics. In addition, it allows us to accurately predict the ICU curve trend in the medium term and assess vaccination. Finally, it is reproducible since we provide open-source codes that consider parameter initialization standardized for every dataset.ConclusionThis work attempts to implement a holistic and general modeling framework for quantitative tracking of the dynamics of any transmissible disease, focusing on accurately predicting the ICU curve trend in the medium term and assessing vaccination. The scientific community could adapt it to evaluate the impact of combined vaccination and NPIs strategies for COVID-19 or any transmissible disease in any country and help ...
    Keywords COVID-19 ; predictive modeling ; epidemiological modeling ; time delays ; vaccination ; practical identifiability ; Public aspects of medicine ; RA1-1270
    Subject code 006
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Probiotic Encapsulation: Bead Design Improves Bacterial Performance during In Vitro Digestion.

    Rojas-Muñoz, Yesica Vanesa / Santagapita, Patricio Román / Quintanilla-Carvajal, María Ximena

    Polymers

    2023  Volume 15, Issue 21

    Abstract: The stability and release properties of all bioactive capsules are strongly related to the composition of the wall material. This study aimed to evaluate the effect of the wall materials during the encapsulation process by ionotropic gelation on the ... ...

    Abstract The stability and release properties of all bioactive capsules are strongly related to the composition of the wall material. This study aimed to evaluate the effect of the wall materials during the encapsulation process by ionotropic gelation on the viability of
    Language English
    Publishing date 2023-11-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15214296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Después de los estudios sociales de la ciencia y tecnología

    Patricio Rojas

    Athenea Digital, Vol 17, Iss

    recomponiendo lo psicológico y la experiencia ante la bifurcación de la naturaleza

    2017  Volume 3

    Abstract: En este artículo presento una discusión teórica sobre cómo se pueden entender lo psicológico y la experiencia luego de los desafíos a los que dichas nociones han sido sometidas por los estudios sociales de ciencia y tecnología (CTS). Los CTS han ... ...

    Abstract En este artículo presento una discusión teórica sobre cómo se pueden entender lo psicológico y la experiencia luego de los desafíos a los que dichas nociones han sido sometidas por los estudios sociales de ciencia y tecnología (CTS). Los CTS han desarrollado una forma de crítica constructivista que se opone a lo que han denominado “bifurcación de la naturaleza”, es decir, la división del mundo entre cualidades primarias —lo material, la realidad en sí—, y cualidades secundarias: experiencia, conciencia y asuntos humanos. Tomando como guía interrogantes surgidas durante una investigación empírica sobre la “experiencia de ser paciente” en usuarios policonsultantes de salud pública, planteo que la crítica a la bifurcación de la naturaleza suele asumir nociones de lo psicológico y la experiencia humana que las sitúan como un callejón sin salida. Argumento entonces que la filosofía de procesos presenta argumentos útiles para rebatir esta simplificación, entendiendo lo psicológico como un flujo de constante co-afectación entre lo humano y el mundo, donde la experiencia no resulta separada de la naturaleza.
    Keywords Experiencia ; Bifurcación de la naturaleza ; Estudios sociales de la ciencia y tecnología ; Psicología social crítica ; History of scholarship and learning. The humanities ; AZ20-999 ; Social sciences (General) ; H1-99
    Language Catalan
    Publishing date 2017-11-01T00:00:00Z
    Publisher Universitat Autonoma de Barcelona
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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