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  1. Article: Corrigendum: The Contrived Mutant p53 Oncogene - Beyond Loss of Functions.

    Sabapathy, Kanaga

    Frontiers in oncology

    2021  Volume 11, Page(s) 665504

    Abstract: This corrects the article DOI: 10.3389/fonc.2015.00276.]. ...

    Abstract [This corrects the article DOI: 10.3389/fonc.2015.00276.].
    Language English
    Publishing date 2021-03-31
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2021.665504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Editorial: Overcoming the cell membrane to target intracellular oncoproteins.

    Brown, Christopher J / Li, Yong / Sabapathy, Kanaga

    Frontiers in oncology

    2023  Volume 13, Page(s) 1222095

    Language English
    Publishing date 2023-07-12
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1222095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correction: Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis.

    Hochedlinger, Konrad / Wagner, Erwin F / Sabapathy, Kanaga

    Oncogene

    2023  Volume 42, Issue 25, Page(s) 2099–2100

    Language English
    Publishing date 2023-05-31
    Publishing country England
    Document type Published Erratum
    ZDB-ID 639046-8
    ISSN 1476-5594 ; 0950-9232
    ISSN (online) 1476-5594
    ISSN 0950-9232
    DOI 10.1038/s41388-023-02719-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2218: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Editorial: Multidisciplinary Approaches in Exploring Cancer Heterogeneity, TME and Therapy Resistance: Perspectives for Systems Medicine.

    Pützer, Brigitte M / Sabapathy, Kanaga

    Frontiers in cell and developmental biology

    2022  Volume 10, Page(s) 842596

    Language English
    Publishing date 2022-02-03
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.842596
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editorial

    Brigitte M. Pützer / Kanaga Sabapathy

    Frontiers in Cell and Developmental Biology, Vol

    Multidisciplinary Approaches in Exploring Cancer Heterogeneity, TME and Therapy Resistance: Perspectives for Systems Medicine

    2022  Volume 10

    Keywords cancer heterogeneity ; tumor immune microenvironment ; development and homeostasis ; cancer evolution ; p53 family transcription factors ; phenotypic plasticity ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: DNA-delivered monoclonal antibodies targeting the p53 R175H mutant epitope inhibit tumor development in mice.

    Chai, Dafei / Wang, Xu / Neeli, Praveen / Zhou, Shan / Yu, Xingfang / Sabapathy, Kanaga / Li, Yong

    Genes & diseases

    2023  Volume 11, Issue 4, Page(s) 100994

    Abstract: The tumor ... ...

    Abstract The tumor suppressor
    Language English
    Publishing date 2023-06-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2821806-1
    ISSN 2352-3042 ; 2352-3042
    ISSN (online) 2352-3042
    ISSN 2352-3042
    DOI 10.1016/j.gendis.2023.04.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Correction to: context-dependent AMPK activation distinctly regulates TAp73 stability and transcriptional activity.

    Li, Dan / Dulloo, Iqbal / Sabapathy, Kanaga

    Signal transduction and targeted therapy

    2021  Volume 6, Issue 1, Page(s) 163

    Language English
    Publishing date 2021-04-24
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2886872-9
    ISSN 2059-3635 ; 2095-9907
    ISSN (online) 2059-3635
    ISSN 2095-9907
    DOI 10.1038/s41392-021-00504-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Corrigendum to 'Understanding p53 functions through p53 antibodies'.

    Sabapathy, Kanaga / Lane, David P

    Journal of molecular cell biology

    2019  Volume 11, Issue 12, Page(s) 1105

    Language English
    Publishing date 2019-12-24
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 2500949-7
    ISSN 1759-4685 ; 1674-2788
    ISSN (online) 1759-4685
    ISSN 1674-2788
    DOI 10.1093/jmcb/mjz110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration.

    Li, Dan / Neo, Suat Peng / Gunaratne, Jayantha / Sabapathy, Kanaga

    Journal of cell science

    2023  Volume 136, Issue 12

    Abstract: Polyamines promote cellular proliferation. Their levels are controlled by ornithine decarboxylase antizyme 1 (Az1, encoded by OAZ1), through the proteasome-mediated, ubiquitin-independent degradation of ornithine decarboxylase (ODC), the rate-limiting ... ...

    Abstract Polyamines promote cellular proliferation. Their levels are controlled by ornithine decarboxylase antizyme 1 (Az1, encoded by OAZ1), through the proteasome-mediated, ubiquitin-independent degradation of ornithine decarboxylase (ODC), the rate-limiting enzyme of polyamine biosynthesis. Az1-mediated degradation of other substrates such as cyclin D1 (CCND1), DNp73 (TP73) or Mps1 regulates cell growth and centrosome amplification, and the currently known six Az1 substrates are all linked with tumorigenesis. To understand whether Az1-mediated protein degradation might play a role in regulating other cellular processes associated with tumorigenesis, we employed quantitative proteomics to identify novel Az1 substrates. Here, we describe the identification of LIM domain and actin-binding protein 1 (LIMA1), also known as epithelial protein lost in neoplasm (EPLIN), as a new Az1 target. Interestingly, between the two EPLIN isoforms (α and β), only EPLIN-β is a substrate of Az1. The interaction between EPLIN-β and Az1 appears to be indirect, and EPLIN-β is degraded by Az1 in a ubiquitination-independent manner. Az1 absence leads to elevated EPLIN-β levels, causing enhanced cellular migration. Consistently, higher LIMA1 levels correlate with poorer overall survival of colorectal cancer patients. Overall, this study identifies EPLIN-β as a novel Az1 substrate regulating cellular migration.
    MeSH term(s) Humans ; Ornithine Decarboxylase/genetics ; Ornithine Decarboxylase/chemistry ; Ornithine Decarboxylase/metabolism ; Ubiquitin/metabolism ; Protein Isoforms ; Carcinogenesis ; Cytoskeletal Proteins
    Chemical Substances ornithine decarboxylase antizyme ; Ornithine Decarboxylase (EC 4.1.1.17) ; Ubiquitin ; Protein Isoforms ; LIMA1 protein, human ; Cytoskeletal Proteins
    Language English
    Publishing date 2023-06-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2993-2
    ISSN 1477-9137 ; 0021-9533
    ISSN (online) 1477-9137
    ISSN 0021-9533
    DOI 10.1242/jcs.260427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1200: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 14: Show issues

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  10. Article ; Online: Correction: Molecular characterization of hepatocarcinogenesis using mouse models.

    Teoh, Wei Wei / Xie, Min / Vijayaraghavan, Aadhitthya / Yaligar, Jadegoud / Tong, Wei Min / Goh, Liang Kee / Sabapathy, Kanaga

    Disease models & mechanisms

    2023  Volume 16, Issue 10

    Language English
    Publishing date 2023-10-19
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2451104-3
    ISSN 1754-8411 ; 1754-8403
    ISSN (online) 1754-8411
    ISSN 1754-8403
    DOI 10.1242/dmm.050441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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