LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 6337

Search options

  1. Article: [No title information]

    Michel, Jean-Marie

    Revue medicale suisse

    2020  Volume 16, Issue 692, Page(s) 964

    Title translation Jean-Marie Michel : « Nous ne sommes pas encore au stade post-COVID ».
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Time Factors
    Language French
    Publishing date 2020-05-06
    Publishing country Switzerland
    Document type Interview
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: [No title information]

    Osiek Marmier, Anouk / Michel, Jean-Marie

    Revue medicale suisse

    2023  Volume 19, Issue 855, Page(s) 2416–2417

    Title translation À Fribourg, notre défi principal est la pénurie de soignants.
    Language French
    Publishing date 2023-12-20
    Publishing country Switzerland
    Document type Interview
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2023.19.855.2416
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Alternative RNA splicing in cancer: what about adult T-cell leukemia?

    Tram, Julie / Mesnard, Jean-Michel / Peloponese, Jean-Marie

    Frontiers in immunology

    2022  Volume 13, Page(s) 959382

    Abstract: Eukaryotic cells employ a broad range of mechanisms to regulate gene expression. Among others, mRNA alternative splicing is a key process. It consists of introns removal from an immature mRNA (pre-mRNA) ...

    Abstract Eukaryotic cells employ a broad range of mechanisms to regulate gene expression. Among others, mRNA alternative splicing is a key process. It consists of introns removal from an immature mRNA (pre-mRNA)
    MeSH term(s) Adult ; Alternative Splicing ; Basic-Leucine Zipper Transcription Factors/genetics ; Cell Transformation, Neoplastic ; Human T-lymphotropic virus 1/genetics ; Humans ; Leukemia-Lymphoma, Adult T-Cell/genetics ; Lymphoma ; RNA, Messenger/metabolism
    Chemical Substances Basic-Leucine Zipper Transcription Factors ; RNA, Messenger
    Language English
    Publishing date 2022-08-01
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.959382
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Book ; Online: Articuler le fantasme et l'histoire

    Gladieu, Marie-Madeleine / Gladieu, Marie-Madeleine / Pottier, Jean-Michel

    (Approches interdisciplinaires de la lecture)

    2015  

    Series title Approches interdisciplinaires de la lecture
    Keywords Literature: history & criticism ; littérature et histoire ; littérature et psychanalyse ; fantasmes dans la littérature ; corps dans la littérature ; création littéraire
    Language fra
    Size 1 electronic resource (254 pages)
    Publisher Éditions et Presses universitaires de Reims
    Publishing place Reims
    Document type Book ; Online
    Note French
    HBZ-ID HT030647809
    ISBN 9782915271966 ; 2915271968
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

  5. Article ; Online: Preface to special issue on advances in quantum chemistry.

    André, Jean-Marie / Bagus, Paul S / Dupuis, Michel

    Journal of physics. Condensed matter : an Institute of Physics journal

    2022  Volume 34, Issue 44

    Language English
    Publishing date 2022-09-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/ac8d41
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Book ; Online: La résonance lectorale

    Gladieu, Marie-Madeleine / Gladieu, Marie-Madeleine / Pottier, Jean-Michel / Trouvé, Alain

    (Approches interdisciplinaires de la lecture)

    2016  

    Series title Approches interdisciplinaires de la lecture
    Keywords Literary theory ; lecture ; sémiotique et littérature ; traduction ; littérarité ; esthétique de la réception ; analyse du discours littéraire
    Language fra
    Size 1 electronic resource (228 pages)
    Publisher Éditions et Presses universitaires de Reims
    Publishing place Reims
    Document type Book ; Online
    Note French
    HBZ-ID HT030647751
    ISBN 9782374960142 ; 2374960145
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

  7. Book ; Online: Paroles de lecteurs

    Chollier, Christine / Gladieu, Marie-Madeleine / Pottier, Jean-Michel / Trouvé, Alain

    (Approches interdisciplinaires de la lecture)

    2018  

    Series title Approches interdisciplinaires de la lecture
    Keywords Theatre management ; Literature: history & criticism ; esthétique de la réception ; intertextualité ; langues ; lecture ; théorie de la lecture ; sémiotique et littérature
    Language fra
    Size 1 electronic resource (274 pages)
    Publisher Éditions et Presses universitaires de Reims
    Publishing place Reims
    Document type Book ; Online
    Note French
    HBZ-ID HT030647499
    ISBN 9782374960630 ; 2374960633
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

  8. Article ; Online: The 3-hit animal models of schizophrenia: Improving strategy to decipher and treat the disease?

    Percelay, Solenn / Lahogue, Caroline / Billard, Jean-Marie / Freret, Thomas / Boulouard, Michel / Bouet, Valentine

    Neuroscience and biobehavioral reviews

    2024  Volume 157, Page(s) 105526

    Abstract: Schizophrenia is a complex disease related to combination and interactions between genetic and environmental factors, with an epigenetic influence. After the development of the first mono-factorial animal models of schizophrenia (1-hit), that reproduced ... ...

    Abstract Schizophrenia is a complex disease related to combination and interactions between genetic and environmental factors, with an epigenetic influence. After the development of the first mono-factorial animal models of schizophrenia (1-hit), that reproduced patterns of either positive, negative and/or cognitive symptoms, more complex models combining two factors (2-hit) have been developed to better fit with the multifactorial etiology of the disease. In the two past decades, a new way to design animal models of schizophrenia have emerged by adding a third hit (3-hit). This review aims to discuss the relevance of the risk factors chosen for the tuning of the 3-hit animal models, as well as the validities measurements and their contribution to schizophrenia understanding. We intended to establish a comprehensive overview to help in the choice of factors for the design of multiple-hit animal models of schizophrenia.
    MeSH term(s) Animals ; Schizophrenia/genetics ; Disease Models, Animal ; Risk Factors
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 282464-4
    ISSN 1873-7528 ; 0149-7634
    ISSN (online) 1873-7528
    ISSN 0149-7634
    DOI 10.1016/j.neubiorev.2023.105526
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Proactive screening algorithm for early onset pneumonia in patients with out-of-hospital cardiac arrest: a before-after implementation study.

    Lemée, Pauline / Chapalain, Xavier / Bailly, Pierre / Sparrow, Rosemary L / Jean-Michel, Vanessa / Prat, Gwenael / Renault, Anne / Tonnelier, Jean-Marie / Aubron, Cécile

    Shock (Augusta, Ga.)

    2024  

    Abstract: Introduction: Early Onset Pneumonia (EOP) occurs in around 50% of critically ill patients with out-of-hospital cardiac arrest (OHCA), and is associated with increased morbidity. Prompt diagnosis of EOP in these patients is difficult because of targeted ... ...

    Abstract Introduction: Early Onset Pneumonia (EOP) occurs in around 50% of critically ill patients with out-of-hospital cardiac arrest (OHCA), and is associated with increased morbidity. Prompt diagnosis of EOP in these patients is difficult because of targeted temperature management and the post-cardiac arrest syndrome. We hypothesized that an algorithm for proactive screening of EOP would improve patient outcomes.
    Methods: We conducted a single-center observational study comparing the outcomes of mechanically-ventilated adult patients with OHCA, before (study period 1) and after (study period 2) implementation of an algorithm for proactive diagnosis of EOP, including an early distal pulmonary specimen. An inverse probability treatment weighted (IPTW) multivariable regression was performed to identify independent parameters associated with duration of mechanical ventilation. A subgroup analysis was conducted in patients alive on day 5 after ICU admission.
    Results: Over the 4-year study period, 190 patients (99 and 91 for study periods 1 and 2, respectively) were enrolled. The overall incidence of EOP was 57.4% and was similar between both study periods. Although there was no difference in the time-interval to antibiotic initiation, study period 2 was independently associated with higher SpO2/FiO2 ratios on days 3 and 4. We also observed a decrease in mechanical ventilation time in study period 2 (4.5 [1 - 11.3] versus 3 [2 - 5.8] days; p = 0.07), and this reached statistical significance in the subgroup analysis of patients alive at day 5 (10 [5 - 17] versus 5 [3 - 9] days, p = 0.01).
    Conclusion: In critically ill patients with OHCA, proactive diagnosis of EOP was not associated with a significant change in the time to antibiotic initiation. Further research is warranted to better define optimal diagnosis and management of EOP in this setting.
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1185432-7
    ISSN 1540-0514 ; 1073-2322
    ISSN (online) 1540-0514
    ISSN 1073-2322
    DOI 10.1097/SHK.0000000000002347
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top