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  1. Article ; Online: Journey of a Thai Taxi Driver and Novel Coronavirus.

    Pongpirul, Wannarat A / Pongpirul, Krit / Ratnarathon, Anuttra C / Prasithsirikul, Wisit

    The New England journal of medicine

    2020  Volume 382, Issue 11, Page(s) 1067–1068

    MeSH term(s) Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; China ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/transmission ; Dyspnea/etiology ; Fever/etiology ; Humans ; Male ; Middle Aged ; Occupational Exposure ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Thailand ; Transportation ; Travel
    Keywords covid19
    Language English
    Publishing date 2020-02-12
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2001621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Immunogenicity of ChAdOx1 nCoV-19 Booster Vaccination Following Two CoronaVac Shots in Healthcare Workers.

    Prasithsirikul, Wisit / Pongpirul, Krit / Nopsopon, Tanawin / Phutrakool, Phanupong / Pongpirul, Wannarat / Samuthpongtorn, Chatpol / Suwanwattana, Pawita / Jongkaewwattana, Anan

    Vaccines

    2022  Volume 10, Issue 2

    Abstract: During the early phase of the COVID-19 pandemic, several countries, including Thailand, provided two shots of CoronaVac to healthcare workers. Whereas ChAdOx1 nCoV-19 is the promising vaccine as the booster dose, the data on immunogenicity when ... ...

    Abstract During the early phase of the COVID-19 pandemic, several countries, including Thailand, provided two shots of CoronaVac to healthcare workers. Whereas ChAdOx1 nCoV-19 is the promising vaccine as the booster dose, the data on immunogenicity when administered after CoronaVac have been limited. The purpose of this study was to evaluate the immunogenicity of ChAdOx1 nCoV-19 as the third dose vaccine in healthcare workers who previously received two shots of CoronaVac. The blood samples were obtained before the third vaccination dose, and one month and three months after vaccination. All participants were measured for humoral immunity including anti-spike IgG and neutralizing antibody by ELISA. Twenty participants were stratified by random samples based on baseline IgG status for a cellular immunity function test at three-month post-vaccination, which included T cell and B cell functions by ELISpot. This study showed significant improvement for both humoral and cellular immunity one month after vaccination. Subgroup analysis indicated a significantly higher neutralizing antibody improvement for the population with a negative anti-spike IgG at baseline. Our study suggests that, while immunity level declines at three months post-vaccination, the level was sufficiently high to protect against SARS-CoV-2.
    Language English
    Publishing date 2022-01-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10020217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: ChAdOx1 nCoV-19 Immunogenicity and Immunological Response Following COVID-19 Infection in Patients Receiving Maintenance Hemodialysis.

    Prasithsirikul, Wisit / Nopsopon, Tanawin / Phutrakool, Phanupong / Suwanwattana, Pawita / Kantagowit, Piyawat / Pongpirul, Wannarat / Jongkaewwattana, Anan / Pongpirul, Krit

    Vaccines

    2022  Volume 10, Issue 6

    Abstract: Patients with end-stage renal disease (ESRD) receiving hemodialysis (HD) were found to have a decreased immune response following mRNA COVID-19 immunization. ChAdOx1 nCoV-19 was a promising COVID-19 vaccine that performed well in the general population, ... ...

    Abstract Patients with end-stage renal disease (ESRD) receiving hemodialysis (HD) were found to have a decreased immune response following mRNA COVID-19 immunization. ChAdOx1 nCoV-19 was a promising COVID-19 vaccine that performed well in the general population, but the evidence on immunogenicity in ESRD with HD patients was limited. Moreover, the immunological response to COVID-19 infection was inconclusive in patients with ESRD and HD. The aim of this study was to investigate the immunogenicity of ChAdOx1 nCoV-19 vaccination and the immunological response after COVID-19 infection in ESRD patients with HD. The blood samples were obtained at baseline, 1-month, and 3-month follow-up after each shot or recovery. All participants were measured for anti-spike IgG by the ELISA method, using Euroimmun. This study found a significant increase in anti-spike IgG after 1 month of two-shot ChAdOx1 nCoV-19 vaccination, followed by a significant decrease after 3 months. On the other hand, the anti-spike IgG was maintained in the post-recovery group. There was no significant difference in the change of anti-spike IgG between the one-shot ChAdOx1 nCoV-19-vaccinated and post-recovery groups for both 1-month and 3-month follow-ups. The seroconversion rate for the vaccinated group was 60.32% at 1 month after one-shot vaccination and slightly dropped to 58.73% at the 3-month follow-up, then was 92.06% at 1 month after two-shot vaccination and reduced to 82.26% at the 3-month follow-up. For the recovered group, the seroconversion rate was 95.65% at 1 month post-recovery and 92.50% at 3-month follow-up. This study demonstrated the immunogenicity of two-dose ChAdOx1 nCoV-19 in ESRD patients with HD for humoral immunity. After COVID-19 infection, the humoral immune response was strong and could be maintained for at least three months.
    Language English
    Publishing date 2022-06-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10060959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Potential dual dengue and SARS-CoV-2 infection in Thailand: A case study.

    Ratnarathon, Anuttra C / Pongpirul, Krit / Pongpirul, Wannarat A / Charoenpong, Lantharita / Prasithsirikul, Wisit

    Heliyon

    2020  Volume 6, Issue 6, Page(s) e04175

    Abstract: Coronavirus disease 2019 (Covid-19) has non-specific clinical and laboratory characteristics that might be similar to other viral infection including dengue. Two Covid-19 cases with 'false-positive' dengue serology have been reported in Singapore but no ... ...

    Abstract Coronavirus disease 2019 (Covid-19) has non-specific clinical and laboratory characteristics that might be similar to other viral infection including dengue. Two Covid-19 cases with 'false-positive' dengue serology have been reported in Singapore but no public health consequence was described. We describe a Thai patient with an initial diagnosis of dengue fever who was later confirmed to also infect with SARSCoV-2. The Covid-19 infection appeared to spread to one family member and one healthcare worker.
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2020.e04175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nurse infected with Covid-19 from a provisional dengue patient.

    Prasitsirikul, Wisit / Pongpirul, Krit / Pongpirul, Wannarat A / Panitantum, Nayot / Ratnarathon, Anuttra C / Hemachudha, Thiravat

    Emerging microbes & infections

    2020  Volume 9, Issue 1, Page(s) 1354–1355

    Abstract: We report a 35-year-old female nurse who possibly received the SARS-CoV-2 virus during the blood sampling of a 35-year-old male patient initially suspected as a dengue infection. The patient had mild thrombocytopenia and positive dengue IgG and IgM ... ...

    Abstract We report a 35-year-old female nurse who possibly received the SARS-CoV-2 virus during the blood sampling of a 35-year-old male patient initially suspected as a dengue infection. The patient had mild thrombocytopenia and positive dengue IgG and IgM whereas the clinicians were not aware of the possibility of false-positive dengue serology revealed in the published case report from Singapore. The nurse put on a pair of gloves but did not wear a mask during the only encounter with this patient. This nosocomial transmission raised a safety concern among healthcare professionals in an area with a relatively low Covid-19 prevalence, especially when the clinical and laboratory characteristics could be confused with other viral infections.
    MeSH term(s) Adult ; Betacoronavirus/pathogenicity ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/transmission ; Dengue/diagnosis ; Dengue/virology ; Dengue Virus/pathogenicity ; Dengue Virus/physiology ; Diagnostic Errors ; Female ; Humans ; Infectious Disease Transmission, Patient-to-Professional ; Male ; Nurse Practitioners ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Thailand
    Keywords covid19
    Language English
    Publishing date 2020-05-19
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 2681359-2
    ISSN 2222-1751 ; 2222-1751
    ISSN (online) 2222-1751
    ISSN 2222-1751
    DOI 10.1080/22221751.2020.1775131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Simultaneously complete but not partial taste and smell losses were associated with SARS-CoV-2 infection.

    Trachootham, Dunyaporn / Thongyen, Supeda / Lam-Ubol, Aroonwan / Chotechuang, Nattida / Pongpirul, Wannarat / Prasithsirikul, Wisit

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2021  Volume 106, Page(s) 329–337

    Abstract: Objectives: The aim of this study was to investigate the association between taste and smell losses and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and to elucidate whether taste preference influences such taste loss.: ... ...

    Abstract Objectives: The aim of this study was to investigate the association between taste and smell losses and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and to elucidate whether taste preference influences such taste loss.
    Methods: A matched case-control study was conducted in 366 Thai participants, including 122 who were confirmed SARS-CoV-2-positive by RT-PCR (case group) and 244 who were SARS-CoV-2-negative (control group). Taste, smell, and appetite changes were assessed by self-reported visual analog scale. Preference for sweet, salty, umami, sour, bitter, and spicy were judged using the validated TASTE-26 questionnaire.
    Results: Partial taste and smell losses were observed in both groups, while complete losses (ageusia and anosmia) were detected only in the case group. Moreover, only ageusia and anosmia were associated with SARS-CoV-2 positivity (P < 0.001, odds ratio of 14.5 and 27.5, respectively). Taste, smell, and appetite scores were more severely reduced in the case group (P < 0.0001). Multivariate analysis showed that anosmia and ageusia were the best predictors of SARS-CoV-2 positivity, followed by appetite loss and fever. Simultaneous losses of taste and smell but not taste preferences were associated with SARS-CoV-2 positivity (P < 0.01, odds ratio 2.28).
    Conclusions: Complete, but not partial, losses of taste and smell were the best predictors of SARS-CoV-2 infection. During the current COVID-19 pandemic, healthy persons with sudden simultaneous complete loss of taste and smell should be screened for COVID-19.
    MeSH term(s) Adult ; Ageusia/complications ; Anosmia/complications ; COVID-19/epidemiology ; COVID-19/physiopathology ; Case-Control Studies ; Humans ; Male ; Middle Aged ; Pandemics
    Language English
    Publishing date 2021-04-02
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2021.03.083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Potential dual dengue and SARS-CoV-2 infection in Thailand

    Ratnarathon, Anuttra C. / Pongpirul, Krit / Pongpirul, Wannarat A. / Charoenpong, Lantharita / Prasithsirikul, Wisit

    Heliyon

    A case study

    2020  Volume 6, Issue 6, Page(s) e04175

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2020.e04175
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Potential dual dengue and SARS-CoV-2 infection in Thailand

    Anuttra C. Ratnarathon / Krit Pongpirul / Wannarat A. Pongpirul / Lantharita Charoenpong / Wisit Prasithsirikul

    Heliyon, Vol 6, Iss 6, Pp e04175- (2020)

    A case study

    2020  

    Abstract: Coronavirus disease 2019 (Covid-19) has non-specific clinical and laboratory characteristics that might be similar to other viral infection including dengue. Two Covid-19 cases with ‘false-positive’ dengue serology have been reported in Singapore but no ... ...

    Abstract Coronavirus disease 2019 (Covid-19) has non-specific clinical and laboratory characteristics that might be similar to other viral infection including dengue. Two Covid-19 cases with ‘false-positive’ dengue serology have been reported in Singapore but no public health consequence was described. We describe a Thai patient with an initial diagnosis of dengue fever who was later confirmed to also infect with SARSCoV-2. The Covid-19 infection appeared to spread to one family member and one healthcare worker.
    Keywords Public health ; Epidemiology ; Occupational health ; Infectious disease ; Virology ; COVID-19 ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99 ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Nurse infected with Covid-19 from a provisional dengue patient

    Prasitsirikul, Wisit / Pongpirul, Krit / Pongpirul, Wannarat A. / Panitantum, Nayot / Ratnarathon, Anuttra C. / Hemachudha, Thiravat

    Emerging Microbes & Infections

    2020  Volume 9, Issue 1, Page(s) 1354–1355

    Keywords Immunology ; Epidemiology ; Microbiology ; Drug Discovery ; Parasitology ; Virology ; Infectious Diseases ; General Medicine ; covid19
    Language English
    Publisher Informa UK Limited
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 2681359-2
    ISSN 2222-1751
    ISSN 2222-1751
    DOI 10.1080/22221751.2020.1775131
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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