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  1. Article ; Online: Rebuttal from Scott K. Powers, Ashley J. Smuder, David Fuller and Sanford Levine.

    Powers, Scott K / Smuder, Ashley J / Fuller, David / Levine, Sanford

    The Journal of physiology

    2013  Volume 591, Issue 21, Page(s) 5263

    MeSH term(s) Animals ; Diaphragm/pathology ; Humans ; Muscular Atrophy/etiology
    Language English
    Publishing date 2013-11-01
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/jphysiol.2013.261552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Audio / Video: Software tools and user's guides to accompany "Fundamentals of heat and mass transfer, 5th edition" & "Introduction to heat transfer, 4th edition", Frank P. Incropera; David P. DeWitt

    DeWitt, David P / Incropera, Frank P / Klein, Sanford A / Smith, Theodore F

    [Interactive heat transfer 2.0 (IHT 2.0) ; Finite element heat transfer (FEHT)]

    2002  

    Title variant Software tools to accompany Incropera & DeWitt: Fundamentals of heat and mass transfer, fifh edition, and Introduction to heat transfer, fourth edition ; FEHT ; Finite element heat transfer program FEHT ; IHT 2.0 ; Interactive heat transfer 2.0
    Institution IntelliPro
    Language English
    Size 1 CD-ROM
    Edition [Elektronische Ressource]
    Publisher Wiley
    Publishing place New York u.a.
    Document type Book ; Audio / Video
    Note IHT 2.0 developed by Intellipro, Inc., user's manual by: Theodore F. Smith, Jin Wen. - FEHT program and user's guide developed by S. A. Klein, W. A. Beckman, and G. E. Meyers
    Accompanying material User's manual (24, 15 S.)
    ISBN 0471075884 ; 0471204021 ; 9780471075882 ; 9780471204022
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Article: Screening Implications for Distribution of Colorectal Cancer Subsite by Age and Role of Flexible Sigmoidoscopy.

    Lin, Gloria / Hein, David M / Liu, Po-Hong / Singal, Amit G / Sanford, Nina N

    Cancers

    2024  Volume 16, Issue 6

    Abstract: Objectives: ...

    Abstract Objectives:
    Language English
    Publishing date 2024-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16061110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Better and faster is cheaper.

    Sanford Kobayashi, Erica F / Dimmock, David P

    Human mutation

    2022  Volume 43, Issue 11, Page(s) 1495–1506

    Abstract: The rapid pace of advancement in genomic sequencing technology has recently reached a new milestone, with a record-setting time to molecular diagnosis of a mere 8 h. The catalyst behind this achievement is the accumulation of evidence indicating that ... ...

    Abstract The rapid pace of advancement in genomic sequencing technology has recently reached a new milestone, with a record-setting time to molecular diagnosis of a mere 8 h. The catalyst behind this achievement is the accumulation of evidence indicating that quicker results more often make an impact on patient care and lead to healthcare cost savings. Herein, we review the diagnostic and clinical utility of rapid whole genome and rapid whole exome sequencing, the associated reduction in healthcare costs, and the relationship between these outcome measures and time-to-diagnosis.
    MeSH term(s) Chromosome Mapping ; Genetic Testing/methods ; Humans ; Whole Exome Sequencing/methods
    Language English
    Publishing date 2022-06-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1126646-6
    ISSN 1098-1004 ; 1059-7794
    ISSN (online) 1098-1004
    ISSN 1059-7794
    DOI 10.1002/humu.24422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: ‘What is this about? Let’s play this out’: the experience of integrating primary health care registered nurses with school learning and support teams.

    Sanford, Catherine / Saurman, Emily / Dennis, Sarah / Lyle, David

    Australian journal of primary health

    2022  Volume 28, Issue 4, Page(s) 321–329

    Abstract: Changes in public health profiles and moves towards inclusive models of education have led to significant number of students in mainstream schools with special health needs. Addressing these needs requires collaboration between health professionals, ... ...

    Abstract Changes in public health profiles and moves towards inclusive models of education have led to significant number of students in mainstream schools with special health needs. Addressing these needs requires collaboration between health professionals, educators and families. Integrated models of school-based health care can facilitate this collaboration; however, there is little evidence to guide their implementation. The School-Based Primary Health Care Service (SB-PHCS) is one such service that has been established in far west New South Wales. The School-Based Primary Health Care Service embeds health district-employed registered nurses with school learning support teams to increase service access, and improve health and education outcomes for students. We conducted focus groups with nurses and learning support teams to explore their experiences of implementing the School-Based Primary Health Care Service. Focus group transcripts were analysed using framework analysis. We found that defining the role and working across systems were challenges to program implementation, whereas a collaborative culture, relationship building and flexibility in work processes facilitated the integration of nurses into the school teams. We recommend others embarking on similar initiatives involve key stakeholders early in service development, understand each other's systems and processes, and provide clarity about the new role, but plan to adapt the role to fit the context. This study will be of interest to those involved in the implementation of integrated models of school-based health care.
    MeSH term(s) Health Personnel ; Humans ; Learning ; Nurses ; Primary Health Care ; School Health Services
    Language English
    Publishing date 2022-06-07
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2566332-X
    ISSN 1836-7399 ; 1448-7527
    ISSN (online) 1836-7399
    ISSN 1448-7527
    DOI 10.1071/PY21190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Consumption of N

    Chee-Sanford, Joanne / Tian, David / Sanford, Robert

    Microbiology (Reading, England)

    2019  Volume 165, Issue 12, Page(s) 1345–1354

    Abstract: Bacteria affiliated with the phylum Gemmatimonadetes are found in high abundance in many terrestrial and aquatic environments, yet little is known about their metabolic capabilities. Difficulty in their cultivation has prompted interest in identifying ... ...

    Abstract Bacteria affiliated with the phylum Gemmatimonadetes are found in high abundance in many terrestrial and aquatic environments, yet little is known about their metabolic capabilities. Difficulty in their cultivation has prompted interest in identifying better growth conditions for metabolic studies, especially related to their ability to reduce N
    MeSH term(s) Ammonium Compounds/metabolism ; Bacteria/growth & development ; Bacteria/metabolism ; Carbon/metabolism ; Culture Media ; Greenhouse Gases/metabolism ; Nitrates/metabolism ; Nitrites/metabolism ; Nitrous Oxide/metabolism ; Oxidation-Reduction ; Oxygen/analysis ; Oxygen/metabolism
    Chemical Substances Ammonium Compounds ; Culture Media ; Greenhouse Gases ; Nitrates ; Nitrites ; Carbon (7440-44-0) ; Nitrous Oxide (K50XQU1029) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2019-10-17
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1180712-x
    ISSN 1465-2080 ; 1350-0872
    ISSN (online) 1465-2080
    ISSN 1350-0872
    DOI 10.1099/mic.0.000847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Apolipoprotein A-I vascular gene therapy reduces vein-graft atherosclerosis.

    Bi, Lianxiang / Wacker, Bradley K / Komandur, Kaushik / Sanford, Nicole / Dichek, David A

    Molecular therapy. Methods & clinical development

    2023  Volume 30, Page(s) 558–572

    Abstract: Coronary artery venous bypass grafts typically fail because of atherosclerosis driven by lipid and macrophage accumulation. Therapy for vein-graft atherosclerosis is limited to statin drugs, which are only modestly effective. We hypothesized that ... ...

    Abstract Coronary artery venous bypass grafts typically fail because of atherosclerosis driven by lipid and macrophage accumulation. Therapy for vein-graft atherosclerosis is limited to statin drugs, which are only modestly effective. We hypothesized that transduction of vein-graft endothelium of fat-fed rabbits with a helper-dependent adenovirus expressing apolipoprotein AI (HDAdApoAI) would reduce lipid and macrophage accumulation. Fat-fed rabbits received bilateral external jugular vein-to-carotid artery interposition grafts. Four weeks later, one graft per rabbit (n = 23 rabbits) was infused with HDAdApoAI and the contralateral graft with HDAdNull. Grafts were harvested 12 weeks later. Paired analyses of grafts were performed, with vein graft cholesterol, intimal lipid, and macrophage content as the primary endpoints. HDAd genomes were detected in all grafts.
    Language English
    Publishing date 2023-08-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2872938-9
    ISSN 2329-0501 ; 2329-0501
    ISSN (online) 2329-0501
    ISSN 2329-0501
    DOI 10.1016/j.omtm.2023.08.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7107: Show issues Location:
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  8. Article ; Online: The relationship between hematologic malignancies on male hypogonadism: a scoping review.

    Roth, Bradley / Moukhtar Hammad, Muhammed A / Sanford, Daniel I / Piper, Molly / Barham, David W / Yafi, Faysal A / Jenkins, Lawrence C

    Sexual medicine reviews

    2024  

    Abstract: Introduction: The associated symptoms of hypogonadism have been reported in patients with various types of cancer. However, the prevalence and significance of hypogonadism among certain hematologic malignancies have not been completely summarized in ... ...

    Abstract Introduction: The associated symptoms of hypogonadism have been reported in patients with various types of cancer. However, the prevalence and significance of hypogonadism among certain hematologic malignancies have not been completely summarized in recent literature.
    Objective: In this review we aimed to examine the current literature on hypogonadism in patients with hematologic malignancies, with emphasis on leukemias, lymphomas, and multiple myeloma (MM).
    Methods: This review included relevant studies published before July 2023 that were retrieved through a search of PubMed using the keywords "hematologic cancer," "hematologic malignancy," blood cancer," "leukemia," "lymphoma," "hypogonadism," "multiple myeloma," and "testosterone."
    Results: The search yielded 214 studies, of which 21 met the inclusion criteria. Commonly reported findings were that patients who had received hematopoietic stem cell therapy for acute lymphoblastic leukemia and acute myelogenous leukemia as children had laboratory-confirmed hypogonadism as adults. However, the impact of these diseases on hypogonadal symptoms was variable in these studies.Studies reporting on lymphoma and hypogonadism had mixed results, with some studies finding that the degree of cytotoxic chemotherapy was associated with hypogonadism, while others showed no correlation. Regardless, multiple studies found that hypogonadism secondary to lymphoma treatment and symptoms of hypogonadism had no apparent association.The most comprehensive assessment of the frequency of hypogonadism in an MM cohort found that 74% of 561 MM patients were classified as hypogonadal compared to 33% of patients in a control population. Testosterone supplementation was found to lower interleukin-6 levels, which could potentially help manage some of the adverse effects of MM, including decreased bone mineral density.
    Conclusion: There is a relationship between hematologic malignancies and hypogonadism, which is likely multifactorial. In this review we established that the most plausible factors are related to the secondary effects of gonadotoxic treatments and/or systemic inflammatory responses to the diseases.
    Language English
    Publishing date 2024-03-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2722257-3
    ISSN 2050-0521 ; 2050-0513
    ISSN (online) 2050-0521
    ISSN 2050-0513
    DOI 10.1093/sxmrev/qeae017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6997: Show issues Location:
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  9. Article ; Online: Management of Acute Myeloid Leukemia: A Review for General Practitioners in Oncology.

    Stubbins, Ryan J / Francis, Annabel / Kuchenbauer, Florian / Sanford, David

    Current oncology (Toronto, Ont.)

    2022  Volume 29, Issue 9, Page(s) 6245–6259

    Abstract: Acute myeloid leukemia (AML) is a hematologic malignancy that most frequently develops in older adults. Overall, AML is associated with a high mortality although advancements in genetic risk stratification and new treatments are leading to improvements ... ...

    Abstract Acute myeloid leukemia (AML) is a hematologic malignancy that most frequently develops in older adults. Overall, AML is associated with a high mortality although advancements in genetic risk stratification and new treatments are leading to improvements in outcomes for some subgroups. In this review, we discuss an individualized approach to intensive therapy with a focus on the role of recently approved novel therapies as well as the selection of post-remission therapies for patients in first remission. We discuss the management of patients with relapsed and refractory AML, including the role of targeted treatment and allogeneic stem cell transplant. Next, we review non-intensive treatment for older and unfit AML patients including the use of azacitidine and venetoclax. Finally, we discuss the integration of palliative care in the management of patients with AML.
    MeSH term(s) Aged ; Azacitidine ; General Practitioners ; Hematopoietic Stem Cell Transplantation ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Leukemia, Myeloid, Acute/therapy
    Chemical Substances Azacitidine (M801H13NRU)
    Language English
    Publishing date 2022-08-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol29090491
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The influence of body painting on L4 spinous process palpation accuracy in novice palpators.

    Scogin, William M / Sanford, David / Greenway, Mary Beth / Ledbetter, Maria / Washmuth, Nicholas B

    The Journal of manual & manipulative therapy

    2023  , Page(s) 1–6

    Abstract: Objectives: Current literature remains inconclusive regarding the best methodology to accurately palpate lumbar spinous processes (SP). Body painting (BP) uses markers to draw anatomical structures on the skin's surface. While BP can be a useful tool ... ...

    Abstract Objectives: Current literature remains inconclusive regarding the best methodology to accurately palpate lumbar spinous processes (SP). Body painting (BP) uses markers to draw anatomical structures on the skin's surface. While BP can be a useful tool for engaging learners, it is unknown whether it improves palpation accuracy. The purpose of this study was to investigate whether the addition of body painting to palpation education improves lumbar spinous process palpation accuracy in first-year Doctor of Physical Therapy (DPT) students.
    Methods: Thirty-eight DPT students were randomized into a traditional palpation group and a body painting (BP) group. Each group received identical instruction on palpating the lumbar spine, with the BP group additionally drawing lumbar SPs on their laboratory partner with a marker. Students were then assessed on their ability to accurately palpate the L4 SP on randomly assigned subjects. Two Certified Registered Nurse Anesthetists (CRNAs) used ultrasound imaging to confirm the location of each student's palpation. Palpation time was also recorded. The BP group also completed a survey on the learning experience.
    Results: Forty-five percent of students were able to accurately palpate the L4 SP. There was no significant difference (
    Discussion/conclusion: While body painting was an enjoyable activity to incorporate into palpation laboratory, it is unclear whether it enhanced lumbar SP palpation accuracy in first-year DPT students.
    Language English
    Publishing date 2023-11-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 920432-5
    ISSN 2042-6186 ; 1066-9817
    ISSN (online) 2042-6186
    ISSN 1066-9817
    DOI 10.1080/10669817.2023.2278264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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