LIVIVO - Search results -

Search results

Result 1 - 10 of total 271

Search options

Article ; Online: Management of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis with Intracapsular Tonsillectomy.

Ezeh, Uche C / Kahn, Philip J / April, Max M

2023 Volume 134, Issue 4, Page(s) 1967–1969

Abstract: Objective: This study aimed to present 2 children clinically diagnosed with periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome and treated with intracapsular tonsillectomy with adenoidectomy (ITA).: Methods: We conducted ... ...

Abstract	Objective: This study aimed to present 2 children clinically diagnosed with periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome and treated with intracapsular tonsillectomy with adenoidectomy (ITA). Methods: We conducted a retrospective analysis of 2 children who were referred for an otolaryngology consultation between 2019 and 2022 for surgical treatment of PFAPA syndrome. Both patients had symptoms strongly suggestive of PFAPA and were at risk for total tonsillectomy (TT) complications. ITA was performed using a microdebrider. Both patients were followed up postoperatively to assess for symptomatic resolution and complications. Results: Two children exhibited recurrent febrile episodes prior to ITA. The procedure was efficacious in both patients, with neither experiencing postoperative complications or recurring PFAPA symptoms for over 1 year after surgery. Conclusion: Our study reported on the use of ITA as a surgical treatment option for PFAPA. We showed that ITA eliminated febrile attacks and was safely performed without postoperative complications in 2 pediatric patients after 1-year follow-up. Future studies involving larger cohorts of PFAPA patients and lengthier follow-ups will need to be conducted to further evaluate ITA as a surgical option. Laryngoscope, 134:1967-1969, 2024.
MeSH term(s)	Child ; Humans ; Tonsillectomy/methods ; Stomatitis, Aphthous/surgery ; Retrospective Studies ; Pharyngitis/surgery ; Lymphadenitis/diagnosis ; Lymphadenitis/surgery ; Lymphadenopathy ; Amyloidosis/surgery ; Fever/surgery ; Fever/complications ; Syndrome ; Postoperative Complications/surgery
Language	English
Publishing date	2023-08-19
Publishing country	United States
Document type	Case Reports
ZDB-ID	80180-x
ISSN	1531-4995 ; 0023-852X
ISSN (online)	1531-4995
ISSN	0023-852X
DOI	10.1002/lary.30969
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ul II Zs.82: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Lupus anti-coagulant hypoprothrombinemia syndrome across different ages: a case report and review of the literature.

Chumsky, Jessica / Kahn, Philip J / Carroll, William L / Pierce, Kristyn A / Hillier, Kirsty

Clinical rheumatology

2023 Volume 42, Issue 8, Page(s) 2231–2236

Abstract: Lupus anti-coagulant hypoprothrombinemia syndrome (LAHPS) is a rare condition that can be difficult to treat. It increases the risk of thrombosis and bleeding due to the presence of lupus anti-coagulant and factor II deficiency, respectively. There are a ...

Abstract	Lupus anti-coagulant hypoprothrombinemia syndrome (LAHPS) is a rare condition that can be difficult to treat. It increases the risk of thrombosis and bleeding due to the presence of lupus anti-coagulant and factor II deficiency, respectively. There are a limited number of cases described in the literature. Herein we describe a case of LAHPS with bleeding symptoms as a first clinical manifestation of systemic lupus erythematosus (SLE) in an 8-year-old female. She has had multiple recurrences of her bleeding symptoms, requiring treatment with steroids, cyclophosphamide, mycophenolate mofetil, and rituximab. Her course was later complicated by development of arthritis and lupus nephritis. Her complicated course provides a new perspective on the clinical course and treatment of LAHPS. We also present a comprehensive literature review which demonstrates the difficulty in treating patients with LAHPS with underlying SLE and the variability of the clinical course and management of LAHPS depending on the age at presentation.
MeSH term(s)	Humans ; Female ; Child ; Hypoprothrombinemias/complications ; Hypoprothrombinemias/diagnosis ; Hypoprothrombinemias/drug therapy ; Lupus Coagulation Inhibitor ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/drug therapy ; Cyclophosphamide/therapeutic use ; Hemorrhage/complications ; Disease Progression
Chemical Substances	Lupus Coagulation Inhibitor ; Cyclophosphamide (8N3DW7272P)
Language	English
Publishing date	2023-05-08
Publishing country	Germany
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	604755-5
ISSN	1434-9949 ; 0770-3198
ISSN (online)	1434-9949
ISSN	0770-3198
DOI	10.1007/s10067-023-06619-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1740: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Synchronous disease onset and flares in siblings with PFAPA.

Dammeyer, Kristen L / Schneider, Amanda / April, Max M / Kahn, Philip J

Pediatric rheumatology online journal

2022 Volume 20, Issue 1, Page(s) 87

Abstract: Background: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is a clinical syndrome of unclear etiology. PFAPA has generally been considered a non-hereditary fever syndrome; however, this has been called into question with ...

Abstract	Background: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is a clinical syndrome of unclear etiology. PFAPA has generally been considered a non-hereditary fever syndrome; however, this has been called into question with recent reports of family clustering. Few reports have been published describing siblings with PFAPA. To our knowledge, this is the first report of siblings with near simultaneous onset of disease followed by synchronous disease flares. Case presentation: We describe the case of near simultaneous onset of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis in siblings followed by synchronous disease flares of clear frequency and nearly identical character. Flares were characterized predominantly by fever, aphthous ulceration, cervical lymphadenitis, and the absence of infection. The fever episodes demonstrated a robust response to glucocorticoids and recurred in the same staggered manner every four weeks, with complete absence of symptoms and normal growth and development between episodes. Nine months after onset, the older sibling, a 5-year-old female, underwent tonsillectomy resulting in dramatic resolution of episodes. At the same time, her 2-year-old sister experienced resolution of her fever episodes, though she did not undergo tonsillectomy herself. Conclusion: This is an unusual case of simultaneous onset PFAPA followed by synchronous disease flares. PFAPA is an uncommon clinical syndrome, and it is rarely diagnosed in siblings. The etiology of PFAPA remains unclear. Though the disease is classically considered sporadic, there is a growing body of evidence to suggest that PFAPA may be heritable.
MeSH term(s)	Child, Preschool ; Female ; Fever/diagnosis ; Fever/etiology ; Humans ; Lymphadenitis/diagnosis ; Pharyngitis/diagnosis ; Siblings ; Stomatitis, Aphthous/diagnosis ; Syndrome ; Tonsillectomy/methods
Language	English
Publishing date	2022-10-05
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2279468-2
ISSN	1546-0096 ; 1546-0096
ISSN (online)	1546-0096
ISSN	1546-0096
DOI	10.1186/s12969-022-00744-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Multisystem Inflammatory Syndrome in Children.

Shust, Gail F / Soma, Vijaya L / Kahn, Philip / Ratner, Adam J

Pediatrics in review

2021 Volume 42, Issue 7, Page(s) 399–401

MeSH term(s)	COVID-19/complications ; Child ; Humans ; SARS-CoV-2 ; Syndrome ; Systemic Inflammatory Response Syndrome
Language	English
Publishing date	2021-05-20
Publishing country	United States
Document type	Editorial
ZDB-ID	774515-1
ISSN	1526-3347 ; 0191-9601
ISSN (online)	1526-3347
ISSN	0191-9601
DOI	10.1542/pir.2020-004770
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 2595: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 53: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Anifrolumab for Adolescent Discoid Lupus Erythematosus.

Shaw, Katharina S / Rajeh, Ahmad / Le, Todd / Kahn, Philip J / Oza, Vikash S / Arkin, Lisa M / Vleugels, Ruth Ann

JAMA network open

2023 Volume 6, Issue 10, Page(s) e2338200

MeSH term(s)	Humans ; Adolescent ; Antibodies, Monoclonal, Humanized/therapeutic use ; Lupus Erythematosus, Discoid/drug therapy
Chemical Substances	anifrolumab (38RL9AE51Q) ; Antibodies, Monoclonal, Humanized
Language	English
Publishing date	2023-10-02
Publishing country	United States
Document type	Letter
ISSN	2574-3805
ISSN (online)	2574-3805
DOI	10.1001/jamanetworkopen.2023.38200
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Juvenile idiopathic arthritis: an update for the clinician.

Kahn, Philip

Bulletin of the NYU hospital for joint diseases

2012 Volume 70, Issue 3, Page(s) 152–166

Abstract: Juvenile idiopathic arthritis (JIA) comprises a collection of all forms of chronic arthritis in childhood with no apparent cause. JIA is the most common rheumatic disease in children, and may result in significant pain, joint deformity, and growth ... ...

Abstract	Juvenile idiopathic arthritis (JIA) comprises a collection of all forms of chronic arthritis in childhood with no apparent cause. JIA is the most common rheumatic disease in children, and may result in significant pain, joint deformity, and growth impairment, with persistence of active arthritis into adulthood. Prior to the mid 1990s, the therapeutic armamentarium for JIA was more limited, utilizing non- specific agents, many with significant adverse effects. With the relatively recent use of biologics, one can provide more target-specific therapy, which may be better tolerated. Through continued translational research and clinical trials, one better understands the biology mediating disease, with the hope of offering safer, more effective medicine, and potential cure. This review will outline the clinical features of JIA, as well as provide the latest updates in current and future pharmacotherapy.
MeSH term(s)	Adolescent ; Animals ; Antirheumatic Agents/adverse effects ; Antirheumatic Agents/therapeutic use ; Arthritis, Juvenile/diagnosis ; Arthritis, Juvenile/drug therapy ; Arthritis, Juvenile/epidemiology ; Arthritis, Juvenile/immunology ; Biological Products/adverse effects ; Biological Products/therapeutic use ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Predictive Value of Tests ; Remission Induction ; Treatment Outcome
Chemical Substances	Antirheumatic Agents ; Biological Products
Language	English
Publishing date	2012
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	390411-8
ISSN	1936-9727 ; 2328-5273 ; 1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
ISSN (online)	1936-9727 ; 2328-5273
ISSN	1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uk I Zs.233: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Neutrophilic dermatosis in a patient with an IKZF1 variant and a review of monogenic autoinflammatory disorders presenting with neutrophilic dermatoses.

Guirguis, Justina / Iosim, Sonia / Jones, Derek / Likhite, Maryel / Chen, Fei / Kesserwan, Chimene / Gindin, Tatyana / Kahn, Philip J / Beck, David / Oza, Vikash S / Hillier, Kirsty

Pediatric dermatology

2024

Abstract: Monogenic diseases of immune dysregulation should be considered in the evaluation of children presenting with recurrent neutrophilic dermatoses in association with systemic signs of inflammation, autoimmune disease, hematologic abnormalities, and ... ...

Abstract	Monogenic diseases of immune dysregulation should be considered in the evaluation of children presenting with recurrent neutrophilic dermatoses in association with systemic signs of inflammation, autoimmune disease, hematologic abnormalities, and opportunistic or recurrent infections. We report the case of a 2-year-old boy presenting with a neutrophilic dermatosis, found to have a novel likely pathogenic germline variant of the IKAROS Family Zinc Finger 1 (IKZF1) gene; the mutation likely results in a loss of function dimerization defective protein based on reports and studies of similar variants. IKZF1 variants could potentially lead to aberrant neutrophil chemotaxis and development of neutrophilic dermatoses. Long-term surveillance is required to monitor the development of hematologic malignancy, autoimmunity, immunodeficiency, and infection in patients with pathogenic IKZF1 germline variants.
Language	English
Publishing date	2024-02-27
Publishing country	United States
Document type	Case Reports
ZDB-ID	605539-4
ISSN	1525-1470 ; 0736-8046
ISSN (online)	1525-1470
ISSN	0736-8046
DOI	10.1111/pde.15566
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1882: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A letter to the editor: The effects of alcohol use on brain glutamate in first episode psychosis.

King, Bridget / Kempton, Matthew J / Broberg, Brian V / Merritt, Kate / Barker, Gareth J / Lythgoe, David J / Perez-Iglesias, Rocio / Baandrup, Lone / Düring, Signe W / Stone, James M / Rostrup, Egill / Sommer, Iris E / Glenthøj, Birte / Kahn, René S / Dazzan, Paola / McGuire, Philip K / Egerton, Alice

Schizophrenia research

2024 Volume 266, Page(s) 234–236

MeSH term(s)	Humans ; Glutamic Acid ; Psychotic Disorders ; Brain/diagnostic imaging ; Proton Magnetic Resonance Spectroscopy
Chemical Substances	Glutamic Acid (3KX376GY7L)
Language	English
Publishing date	2024-03-01
Publishing country	Netherlands
Document type	Letter
ZDB-ID	639422-x
ISSN	1573-2509 ; 0920-9964
ISSN (online)	1573-2509
ISSN	0920-9964
DOI	10.1016/j.schres.2024.02.013
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2351: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 543: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Symptom resolution following a repeat concussion within the same athlete.

Tang, Alan R / Williams, Kristen L / Davis, Philip J / Grusky, Alan Z / Hou, Brian Q / Hajdu, Katherine S / Yengo-Kahn, Aaron M / Zuckerman, Scott L / Terry, Douglas P

Brain injury

2024 Volume 38, Issue 4, Page(s) 295–303

Abstract: Introduction: Repeat sport-related concussion (SRC) is anecdotally associated with prolonged recovery. Few studies have examined repeat concussion within the same athlete. We sought to explore differences in symptom burden and recovery outcomes in an ... ...

Abstract	Introduction: Repeat sport-related concussion (SRC) is anecdotally associated with prolonged recovery. Few studies have examined repeat concussion within the same athlete. We sought to explore differences in symptom burden and recovery outcomes in an individual athlete's initial and repeat SRC. Methods: A retrospective within-subject cohort study of athletes aged 12-23 years diagnosed with two separate SRCs from 11/2017-10/2020 was conducted. Primary outcomes were initial symptom severity and time-to-symptom-resolution. Secondary outcomes included return-to-learn (RTL) and return-to-play (RTP) duration. Results: Of 868 athletes seen, 47 athletes presented with repeat concussions. Median time between concussions was 244 days (IQR 136-395). Comparing initial to repeat concussion, no differences were observed in time-to-clinic (4.3 ± 7.3vs.3.7 ± 4.6 days, Conclusion: No significant differences in symptom duration and RTP/RTL were seen between initial/repeat concussion.
MeSH term(s)	Humans ; Athletic Injuries/complications ; Athletic Injuries/diagnosis ; Cohort Studies ; Retrospective Studies ; Brain Concussion/diagnosis ; Brain Concussion/complications ; Athletes
Language	English
Publishing date	2024-02-09
Publishing country	England
Document type	Journal Article
ZDB-ID	639115-1
ISSN	1362-301X ; 0269-9052
ISSN (online)	1362-301X
ISSN	0269-9052
DOI	10.1080/02699052.2024.2311341
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2242: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Juvenile idiopathic arthritis - what the clinician needs to know.

Kahn, Philip J

Bulletin of the Hospital for Joint Disease (2013)

2013 Volume 71, Issue 3, Page(s) 194–199

Abstract: Juvenile idiopathic arthritis (JIA) includes several forms of chronic arthritis in childhood with no apparent cause. JIA is the most common rheumatic disease in children, and may result in pain, joint deformity, and growth im- pairment, with possible ... ...

Abstract	Juvenile idiopathic arthritis (JIA) includes several forms of chronic arthritis in childhood with no apparent cause. JIA is the most common rheumatic disease in children, and may result in pain, joint deformity, and growth im- pairment, with possible persistent active arthritis into adulthood. Prior treatment involved non-specific agents, several with significant adverse effects. The recent use of biologics now provides target-specific therapy, which may be better tolerated. Through continued translational research and clinical trials, one better understands the biology mediating disease, with the hope of offering safer, more effective medicine, and potential cure. This review will outline the clinical features of JIA, as well as provide the latest updates in treatment.
MeSH term(s)	Age Factors ; Animals ; Antirheumatic Agents/therapeutic use ; Arthritis, Juvenile/diagnosis ; Arthritis, Juvenile/drug therapy ; Arthritis, Juvenile/immunology ; Child ; Disease Progression ; Humans ; Remission Induction ; Treatment Outcome
Chemical Substances	Antirheumatic Agents
Language	English
Publishing date	2013
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	390411-8
ISSN	2328-5273 ; 1936-9727 ; 1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
ISSN (online)	2328-5273 ; 1936-9727
ISSN	1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uk I Zs.233: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito