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  1. Article ; Online: The current landscape of the antimicrobial peptide melittin and its therapeutic potential.

    Zhang, Hai-Qian / Sun, Chengbiao / Xu, Na / Liu, Wensen

    Frontiers in immunology

    2024  Volume 15, Page(s) 1326033

    Abstract: Melittin, a main component of bee venom, is a cationic amphiphilic peptide with a linear α-helix structure. It has been reported that melittin can exert pharmacological effects, such as antitumor, antiviral and anti-inflammatory ... ...

    Abstract Melittin, a main component of bee venom, is a cationic amphiphilic peptide with a linear α-helix structure. It has been reported that melittin can exert pharmacological effects, such as antitumor, antiviral and anti-inflammatory effects
    MeSH term(s) Melitten/pharmacology ; Melitten/chemistry ; Melitten/metabolism ; Antimicrobial Peptides ; Bee Venoms/pharmacology ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Antiviral Agents
    Chemical Substances Melitten (20449-79-0) ; Antimicrobial Peptides ; Bee Venoms ; Anti-Inflammatory Agents ; Antiviral Agents
    Language English
    Publishing date 2024-01-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1326033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Adenosine stimulates the basolateral 50 pS K

    Liu, Hao / Sun, Qi / Ding, Zheng / Shi, Wensen / Wang, Wen-Hui / Zhang, Chengbiao

    Frontiers in physiology

    2023  Volume 14, Page(s) 1242975

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-08-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1242975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The PTB and PRR domains of numb regulate neurite outgrowth by influencing voltage-gated calcium channel expression and kinetics.

    Wang, Guodong / Zhang, Zhengyan / Li, Junmei / Han, Jinhong / Lu, Chengbiao

    Brain research bulletin

    2024  Volume 207, Page(s) 110876

    Abstract: Numb is an evolutionarily conserved protein that regulates the differentiation of neuronal progenitor cells through unknown mechanisms. Numb has four alternative splice variants with different lengths of phosphotyrosine-binding (PTB) and proline-rich ... ...

    Abstract Numb is an evolutionarily conserved protein that regulates the differentiation of neuronal progenitor cells through unknown mechanisms. Numb has four alternative splice variants with different lengths of phosphotyrosine-binding (PTB) and proline-rich regions (PRR) domains. In this study, we demonstrated that Numb expression was increased in the primary cultures of rat cortical and hippocampal neurons over time in vitro, and Numb antisense inhibited neurite outgrowth. We verified that cells overexpressing short PTB (SPTB) or long PTB (LPTB) domains exhibited differentiation or proliferation, respectively. SPTB-mediated differentiation was related to the PRR domains, as cells expressing SPTB/LPRR had longer dendrites and more branched dendrites than cells expressing SPTB/SPRR. The differentiation of both cell types was completely blocked by the Ca
    MeSH term(s) Rats ; Animals ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Neurons/metabolism ; Calcium Channels/genetics ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Protein Isoforms/pharmacology ; Neuronal Outgrowth ; Calcium/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism
    Chemical Substances Membrane Proteins ; Calcium Channels ; Protein Isoforms ; Calcium (SY7Q814VUP) ; numb protein, rat ; Intracellular Signaling Peptides and Proteins
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197620-5
    ISSN 1873-2747 ; 0361-9230
    ISSN (online) 1873-2747
    ISSN 0361-9230
    DOI 10.1016/j.brainresbull.2024.110876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1243: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Robust Superamphiphobic Coating Applied to Grease-Proof Mining Transformer Components.

    Zhang, Jiaxu / Zhu, Lina / Wang, Chengbiao / Huang, Jinxia / Guo, Zhiguang

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 22, Page(s) 7968–7978

    Abstract: The iron core and heat sink in a mining transformer are susceptible to damage from oil spills or the harsh mine environment; the deterioration of oil products in the underground environment and transformers produce massive amounts of harmful liquid ... ...

    Abstract The iron core and heat sink in a mining transformer are susceptible to damage from oil spills or the harsh mine environment; the deterioration of oil products in the underground environment and transformers produce massive amounts of harmful liquid substances, which may lead to unnecessary economic losses in drilling engineering. To overcome this issue, a convenient and economical way to protect transformer components was developed. Herein, we proposed an air spray technology at room temperature for the preparation of antigreasy superamphiphobic coatings, which are suitable for bulk metallic glass transformer cores and ST13 heat sinks. The addition of polypyrrole powder effectively improves the thermal conductivity and specific heat of the coating in the range of 50-70 °C. More importantly, the fabricated coating has excellent repellency to liquids, such as water, ethylene glycerol, hexadecane, and rapeseed oil. Meanwhile, the coating has excellent physical and chemical resistance and outstanding antifouling features, which provide a feasible solution for combating grease pollution and corrosion in the mine environment. Taking multifaceted stability into consideration, this work contributes to enhancing the application of superamphiphobic coatings in the fields of protecting transformer components in the harsh environment or during transformer operation faults.
    Language English
    Publishing date 2023-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c00858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: An injectable and biodegradable zwitterionic gel for extending the longevity and performance of insulin infusion catheters.

    Zhang, Ershuai / Shi, Yuanjie / Han, Xiangfei / Zhu, Hui / Song, Boyi / Yang, Chengbiao / Cao, Zhiqiang

    Nature biomedical engineering

    2023  

    Abstract: Continuous subcutaneous insulin infusion (CSII) is an essential insulin replacement therapy in the management of diabetes. However, the longevity of clinical CSII is limited by skin complications, by impaired insulin absorption and by occlusions ... ...

    Abstract Continuous subcutaneous insulin infusion (CSII) is an essential insulin replacement therapy in the management of diabetes. However, the longevity of clinical CSII is limited by skin complications, by impaired insulin absorption and by occlusions associated with the subcutaneous insertion of CSII catheters, which require replacement and rotation of the insertion site every few days. Here we show that a biodegradable zwitterionic gel covering the tip end of commercial off-the-shelf CSII catheters fully resolves early skin irritations, extends the longevity of catheters and improves the rate of insulin absorption (also with respect to conventional syringe-based subcutaneous injection) for longer than 6 months in diabetic mice, and by 11 days in diabetic minipigs (from 2 to 13 days, under standard CSII-wearing conditions of insulin pump therapy and in a continuous basal-plus-bolus-infusion setting). The implanted gel displayed anti-inflammatory and anti-foreign-body-reaction properties and promoted the local formation of new blood vessels. The gel is subcutaneously injected before the tip of catheter is inserted into it, and should be generally applicable to CSII catheters and other implantable devices.
    Language English
    Publishing date 2023-10-26
    Publishing country England
    Document type Journal Article
    ISSN 2157-846X
    ISSN (online) 2157-846X
    DOI 10.1038/s41551-023-01108-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Alkali and Heavy Metal Copoisoning Resistant Catalytic Reduction of NO

    Shen, Zhi / Liu, Xiangyu / Impeng, Sarawoot / Zhang, Chengbiao / Yan, Tingting / Wang, Penglu / Zhang, Dengsong

    Environmental science & technology

    2022  Volume 56, Issue 8, Page(s) 5141–5149

    Abstract: The catalyst deactivation caused by the coexistence of alkali and heavy metals remains an obstacle for selective catalytic reduction of ... ...

    Abstract The catalyst deactivation caused by the coexistence of alkali and heavy metals remains an obstacle for selective catalytic reduction of NO
    MeSH term(s) Alkalies ; Ammonia ; Cadmium ; Catalysis ; Lewis Acids ; Oxidation-Reduction
    Chemical Substances Alkalies ; Lewis Acids ; Cadmium (00BH33GNGH) ; Ammonia (7664-41-7)
    Language English
    Publishing date 2022-04-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.1c08096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Discovery of Telluride and Selenide in the Giant Pulang Porphyry Cu-Au Deposit, Yunnan Province

    SHEN Qiwu / WANG Dazhao / LENG Chengbiao / YU Haijun / ZHANG Chuanyu / SU Xiaoyu / MAO Jinwei / LIANG Feng

    Yankuang ceshi, Vol 42, Iss 3, Pp 643-

    2023  Volume 646

    Keywords Geology ; QE1-996.5 ; Ecology ; QH540-549.5
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Science Press, PR China
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Corrigendum: A neutralizing bispecific single-chain antibody against SARS-CoV-2 Omicron variant produced based on CR3022.

    Yu, Kaikai / Liu, Bin / Yu, Haotian / Sun, Chengbiao / Wang, Xuefeng / Li, Guorui / Dong, Mingxin / Wang, Yan / Zhang, Jianxu / Xu, Na / Liu, Wensen

    Frontiers in cellular and infection microbiology

    2023  Volume 13, Page(s) 1264974

    Abstract: This corrects the article DOI: 10.3389/fcimb.2023.1155293.]. ...

    Abstract [This corrects the article DOI: 10.3389/fcimb.2023.1155293.].
    Language English
    Publishing date 2023-08-24
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1264974
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Asymmetric Robust Superhydrophobic/Superhydrophilic Janus Membranes for the Moisture Proofing of Oil and Purification of Water.

    Zhang, Jiaxu / Zhu, Lina / Huang, Junfei / Wang, Chengbiao / Huang, Jinxia / Guo, Zhiguang

    Langmuir : the ACS journal of surfaces and colloids

    2022  Volume 38, Issue 34, Page(s) 10611–10620

    Abstract: The performance degradation of oil caused by moisture and water pollution induced by the infiltration of oil can result in huge losses for society. This is especially true of stable emulsified mixtures of oil and water, which are difficult to separate ... ...

    Abstract The performance degradation of oil caused by moisture and water pollution induced by the infiltration of oil can result in huge losses for society. This is especially true of stable emulsified mixtures of oil and water, which are difficult to separate and urgently require a processing method. In this work, a robust Janus membrane prepared by combining simple electrodeposition and spraying processes was used to separate water-in-transformer oil/lubricating oil emulsions and various oil-in-water emulsions. The membrane with outstanding separation efficiency was also endowed high flux to emulsions, even after 10 separation cycles and 100 sand impact tests, indicating that separation ability was retained. Furthermore, the excellent resistance to acidic and alkaline liquids of the superhydrophobic side groups of the membrane increased the possibility of its service in harsh environments. This study's findings reveal great potential regarding the expansion and application of oil-water separation materials.
    Language English
    Publishing date 2022-08-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.2c01496
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Asymmetric Robust Superhydrophobic/Superhydrophilic Janus Membranes for the Moisture Proofing of Oil and Purification of Water

    Zhang, Jiaxu / Zhu, Lina / Huang, Junfei / Wang, Chengbiao / Huang, Jinxia / Guo, Zhiguang

    Langmuir. 2022 Aug. 17, v. 38, no. 34

    2022  

    Abstract: The performance degradation of oil caused by moisture and water pollution induced by the infiltration of oil can result in huge losses for society. This is especially true of stable emulsified mixtures of oil and water, which are difficult to separate ... ...

    Abstract The performance degradation of oil caused by moisture and water pollution induced by the infiltration of oil can result in huge losses for society. This is especially true of stable emulsified mixtures of oil and water, which are difficult to separate and urgently require a processing method. In this work, a robust Janus membrane prepared by combining simple electrodeposition and spraying processes was used to separate water-in-transformer oil/lubricating oil emulsions and various oil-in-water emulsions. The membrane with outstanding separation efficiency was also endowed high flux to emulsions, even after 10 separation cycles and 100 sand impact tests, indicating that separation ability was retained. Furthermore, the excellent resistance to acidic and alkaline liquids of the superhydrophobic side groups of the membrane increased the possibility of its service in harsh environments. This study’s findings reveal great potential regarding the expansion and application of oil–water separation materials.
    Keywords artificial membranes ; electroplating ; hydrophilicity ; hydrophobicity ; oils ; sand ; water pollution ; water purification
    Language English
    Dates of publication 2022-0817
    Size p. 10611-10620.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.2c01496
    Database NAL-Catalogue (AGRICOLA)

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