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  1. Article ; Online: Kawasaki disease and COVID-19; a pretext for a hot topic

    Shahin Jafarpour / Masoumeh Abedini / Amin Saburi

    Journal of the Formosan Medical Association, Vol 120, Iss 5, Pp 1279-

    2021  Volume 1281

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Kawasaki disease and COVID-19; a pretext for a hot topic.

    Jafarpour, Shahin / Abedini, Masoumeh / Saburi, Amin

    Journal of the Formosan Medical Association = Taiwan yi zhi

    2020  Volume 120, Issue 5, Page(s) 1279–1281

    MeSH term(s) COVID-19 ; Child ; Humans ; Mucocutaneous Lymph Node Syndrome ; SARS-CoV-2
    Language English
    Publishing date 2020-12-03
    Publishing country Singapore
    Document type Letter ; Comment
    ZDB-ID 2096659-3
    ISSN 1876-0821 ; 0929-6646
    ISSN (online) 1876-0821
    ISSN 0929-6646
    DOI 10.1016/j.jfma.2020.11.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1041: Show issues Location:
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  3. Article ; Online: The First Presentation of Pediatric COVID-19 With Diabetic Ketoacidosis

    Shahin Jafarpour / Masoumeh Abedini / Fatemeh Eghbal / Amin Saburi

    International Journal of Travel Medicine and Global Health, Vol 8, Iss 3, Pp 131-

    A Unique Case Report

    2020  Volume 133

    Abstract: Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19, is a pandemic infectious disease involved all over the world. Its mortality, especially in cases with additional co-morbidities, is so high that is has attracted the ...

    Abstract Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19, is a pandemic infectious disease involved all over the world. Its mortality, especially in cases with additional co-morbidities, is so high that is has attracted the attention of the world. Diabetes mellitus is known as one of its risk factors for mortality. Case Presentation: A unique case of pediatrics COVID-19 who presented with diabetic ketoacidosis (DKA) is reported in this manuscript as the first presentation. He presented with abdominal pain, nausea, and vomiting. RT-PCR test for COVID-19 via nasal swab was performed, and a positive diagnosis was obtained. Chest CT scan confirmed the diagnosis with multifocal bilateral patchy consolidation. Case was discharged after usual treatment of COVID-19. Conclusion: In pediatrics, this disease can be subtle and have a confusion presentation, but it should be controlled to avoid spread of the disease.
    Keywords pediatrics ; coronavirus ; pneumonia ; diabetes mellitus ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher International Travel Medicine Center of Iran
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Effects of silver nanoparticles coated with anti-HER2 on irradiation efficiency of SKBR3 breast cancer cells.

    Aghamiri, Shahin / Jafarpour, Ali / Shoja, Mohsen

    publication RETRACTED

    IET nanobiotechnology

    2019  Volume 13, Issue 8, Page(s) 808–815

    Abstract: Breast cancer is the second cause of death in the world. Ionising radiation is a potent mutagen that can cause DNA damage, chromosomes breakage, and cell death. In the present study, radiotherapy and nanoparticle-antibodies (ABs) have been combined to ... ...

    Abstract Breast cancer is the second cause of death in the world. Ionising radiation is a potent mutagen that can cause DNA damage, chromosomes breakage, and cell death. In the present study, radiotherapy and nanoparticle-antibodies (ABs) have been combined to enhance the efficacy of cancer cell treatment. Silver nanoparticles (SNP) were synthesised, coated with anti-HER2, and then characterised with different techniques such as X-ray diffraction, dynamic light scattering, transmission electron microscopy, Fourier transform infrared, and UV-Vis spectroscopy. SKBR3 cells were irradiated with cobalt-60 in the presence of nanoparticle-AB as the drug. Cell viability was measured using the diphenyltetrazolium bromide assay, and the cellular status was assessed by Raman spectroscopy. Irradiation considerably decreased cell viability proportionate to the dose increase and post-irradiation time. The surface-enhanced Raman spectroscopy increased the signal in the presence of SNP. Increasing the dose to 2 Gy increased the irradiation resistance, and higher dose increases (4 and 6 Gy) enhanced the irradiation sensitivity. Moreover, the cellular changes induced by irradiation in the presence of the drug were stable after 48 h. The authors results introduced the combination of the drug with radiation as an effective treatment for cancer and Raman spectroscopy as a suitable tool to diagnose effective irradiation doses.
    MeSH term(s) Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Breast Neoplasms/pathology ; Breast Neoplasms/radiotherapy ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Coated Materials, Biocompatible/pharmacology ; Coated Materials, Biocompatible/therapeutic use ; Drug Screening Assays, Antitumor ; Dynamic Light Scattering ; Female ; Gamma Rays/therapeutic use ; Humans ; Materials Testing ; Metal Nanoparticles/chemistry ; Radiation Tolerance/drug effects ; Radiation-Sensitizing Agents/chemical synthesis ; Radiation-Sensitizing Agents/chemistry ; Radiation-Sensitizing Agents/pharmacology ; Radiation-Sensitizing Agents/therapeutic use ; Receptor, ErbB-2/antagonists & inhibitors ; Silver/chemistry ; Silver/pharmacology ; Spectrum Analysis, Raman ; Trastuzumab/chemistry ; Trastuzumab/pharmacology ; Trastuzumab/therapeutic use ; X-Ray Diffraction
    Chemical Substances Antineoplastic Agents ; Coated Materials, Biocompatible ; Radiation-Sensitizing Agents ; Silver (3M4G523W1G) ; ERBB2 protein, human (EC 2.7.10.1) ; Receptor, ErbB-2 (EC 2.7.10.1) ; Trastuzumab (P188ANX8CK)
    Language English
    Publishing date 2019-09-04
    Publishing country United States
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2264529-9
    ISSN 1751-875X ; 1751-8741
    ISSN (online) 1751-875X
    ISSN 1751-8741
    DOI 10.1049/iet-nbt.2018.5258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effect of resveratrol on the radiosensitivity of 5-FU in human breast cancer MCF-7 cells.

    Aghamiri, Shahin / Jafarpour, Ali / Zandsalimi, Farshid / Aghemiri, Mehran / Shoja, Mohsen

    Journal of cellular biochemistry

    2019  Volume 120, Issue 9, Page(s) 15671–15677

    Abstract: The aim of this study was to assess the efficacy of resveratrol (Res) on radiosensitivity of 5-fluorouracil (5-FU) in the spheroid culture of MCF-7 breast cancer cell line using colony formation examination. Spheroids on day 9 with 300 µm diameters were ... ...

    Abstract The aim of this study was to assess the efficacy of resveratrol (Res) on radiosensitivity of 5-fluorouracil (5-FU) in the spheroid culture of MCF-7 breast cancer cell line using colony formation examination. Spheroids on day 9 with 300 µm diameters were treated with 20 µM resveratrol and/or 1 µM 5-FU for one volume doubling time (VDT) (42 hours) and then irradiated with 2 Gy gamma radiation (
    MeSH term(s) Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Breast Neoplasms/radiotherapy ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Combined Modality Therapy ; Female ; Fluorouracil/pharmacology ; Gamma Rays ; Humans ; MCF-7 Cells ; Radiation Tolerance/drug effects ; Radiation Tolerance/radiation effects ; Resveratrol/pharmacology ; Spheroids, Cellular/drug effects
    Chemical Substances Resveratrol (Q369O8926L) ; Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2019-05-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392402-6
    ISSN 1097-4644 ; 0730-2312
    ISSN (online) 1097-4644
    ISSN 0730-2312
    DOI 10.1002/jcb.28836
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1114: Show issues Location:
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  6. Article ; Online: Overcoming the blood-brain barrier in neurodegenerative disorders and brain tumours.

    Ebrahimi, Zahra / Talaei, Sam / Aghamiri, Shahin / Goradel, Nasser Hashemi / Jafarpour, Ali / Negahdari, Babak

    IET nanobiotechnology

    2020  Volume 14, Issue 6, Page(s) 441–448

    Abstract: Drug delivery is one of the major challenges in the treatment of central nervous system disorders. The brain needs to be protected from harmful agents, which are done by the capillary network, the so-called blood-brain barrier (BBB). This protective ... ...

    Abstract Drug delivery is one of the major challenges in the treatment of central nervous system disorders. The brain needs to be protected from harmful agents, which are done by the capillary network, the so-called blood-brain barrier (BBB). This protective guard also prevents the delivery of therapeutic agents to the brain and limits the effectiveness of treatment. For this reason, various strategies have been explored by scientists for overcoming the BBB from disruption of the BBB to targeted delivery of nanoparticles (NPs) and cells and immunotherapy. In this review, different promising brain drug delivery strategies including disruption of tight junctions in the BBB, enhanced transcellular transport by peptide-based delivery, local delivery strategies, NP delivery, and cell-based delivery have been fully discussed.
    MeSH term(s) Animals ; Blood-Brain Barrier/metabolism ; Blood-Brain Barrier/physiology ; Brain Neoplasms/drug therapy ; Brain Neoplasms/metabolism ; Cells, Cultured ; Drug Delivery Systems ; Humans ; Neurodegenerative Diseases/drug therapy ; Neurodegenerative Diseases/metabolism ; Tight Junctions/metabolism
    Language English
    Publishing date 2020-07-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2264529-9
    ISSN 1751-875X ; 1751-875X
    ISSN (online) 1751-875X
    ISSN 1751-875X
    DOI 10.1049/iet-nbt.2019.0351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Targeting siRNA in colorectal cancer therapy: Nanotechnology comes into view.

    Aghamiri, Shahin / Jafarpour, Ali / Malekshahi, Ziba Veisi / Mahmoudi Gomari, Mohammad / Negahdari, Babak

    Journal of cellular physiology

    2019  Volume 234, Issue 9, Page(s) 14818–14827

    Abstract: Colorectal cancer (CRC) is known as one of the most important causes of death and mortality worldwide. Although several efforts have been made for finding new therapies, no achievements have been made in this area. Multidrug resistance (MDR) mechanisms ... ...

    Abstract Colorectal cancer (CRC) is known as one of the most important causes of death and mortality worldwide. Although several efforts have been made for finding new therapies, no achievements have been made in this area. Multidrug resistance (MDR) mechanisms are one of the key factors that could lead to the failure of chemotherapy. Moreover, it has been shown that various chemotherapy drugs are associated with several side effects. Hence, it seems that finding new drugs or new therapeutic platforms is required. Among different therapeutic approaches, utilization of nanoparticles (NPs) for targeting a variety of molecules such as siRNAs are associated with good results for the treatment of CRC. Targeting siRNA-mediated NPs could turn off the effects of oncogenes and MDR-related genes. In the current study, we summarized various siRNAs targeted by NPs which could be used for the treatment of CRC. Moreover, we highlighted other routes such as liposome for targeting siRNAs in CRC therapy.
    Language English
    Publishing date 2019-03-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 3116-1
    ISSN 1097-4652 ; 0021-9541
    ISSN (online) 1097-4652
    ISSN 0021-9541
    DOI 10.1002/jcp.28281
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    Uc I Zs.212: Show issues Location:
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  8. Article ; Online: Quantitative and qualitative assessment of waste produced in sari hospitals

    Mohammad Taha Ebrahimi / Ali Jafarpour / Somayeh Kamgoo / Shahin Aghamiri / Amir Bahador Kazemi / Robabeh Vahidi-Kolur / Nima Danaei

    International Journal of Environmental Health Engineering , Vol 10, Iss 1, Pp 1-

    2021  Volume 1

    Abstract: Aims: The Iranian city of Sari with a green nature has great environmental importance, especially in ecotourism. Thus, the proper management of medical wastes is necessary to maintain a sustainable environment. This study is aimed to determine the ... ...

    Abstract Aims: The Iranian city of Sari with a green nature has great environmental importance, especially in ecotourism. Thus, the proper management of medical wastes is necessary to maintain a sustainable environment. This study is aimed to determine the quantitative and qualitative wastes in the hospitals of Sari. Materials and Methods: This was a cross-sectional study using a descriptive-analytical approach to analyze the infectious and noninfectious wastes of four hospitals in Sari. The data collection instrument was a checklist that was completed on visits to hospitals and observation of cases. Data analysis was performed using Excel and R software programs. Results: The average quantity of the total waste produced in hospitals was 218, 482, 19.5, and 17 kg/day for infectious, household, sharp-cutter, and pharmaceutical wastes, respectively. The rate of hospital waste production for various types of infectious, household, sharp-cutter, and pharmaceutical wastes equaled 1.15, 2.13, 0.09, and 0.28 kg/bed, respectively. Conclusion: Due to the high percentage of infectious wastes, despite considerable efforts to separate wastes, there are still problems in the hospitals that require more attention from the authorities, as well as the incorporation of new methods to render waste safe before it leaves the hospital.
    Keywords hospital waste ; iran ; qualitative and quantitative analysis ; waste management ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental engineering ; TA170-171 ; Environmental sciences ; GE1-350
    Subject code 710
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Effects of Various Substrates and Supplements on King Oyster (Pleurotus eryngii)

    Kazemi Jeznabadi, Elahe / Jafarpour, Mehrdad / Eghbalsaied, Shahin / Pessarakli, Mohammad

    Compost science & utilization

    2017  Volume 25, Issue Suppl.1, Page(s) 1

    Language English
    Document type Article
    ZDB-ID 1171776-2
    ISSN 1065-657X
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 5254: Show issues

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  10. Article ; Online: Diseases and Health Outcomes Registry Systems in I.R. Iran: Successful Initiative to Improve Public Health Programs, Quality of Care, and Biomedical Research.

    Mojarrab, Shahnaz / Rafei, Ali / Akhondzadeh, Shahin / Jeddian, Alireza / Jafarpour, Maryam / Zendehdel, Kazem

    Archives of Iranian medicine

    2017  Volume 20, Issue 11, Page(s) 696–703

    Abstract: Registration systems for diseases and other health outcomes provide important resource for biomedical research, as well as tools for public health surveillance and improvement of quality of care. The Ministry of Health and Medical Education (MOHME) of ... ...

    Abstract Registration systems for diseases and other health outcomes provide important resource for biomedical research, as well as tools for public health surveillance and improvement of quality of care. The Ministry of Health and Medical Education (MOHME) of Iran launched a national program to establish registration systems for different diseases and health outcomes. Based on the national program, we organized several workshops and training programs and disseminated the concepts and knowledge of the registration systems. Following a call for proposals, we received 100 applications and after thorough evaluation and corrections by the principal investigators, we approved and granted about 80 registries for three years. Having strong steering committee, committed executive and scientific group, establishing national and international collaboration, stating clear objectives, applying feasible software, and considering stable financing were key components for a successful registry and were considered in the evaluation processes. We paid particulate attention to non-communicable diseases, which constitute an emerging public health problem. We prioritized establishment of regional population-based cancer registries (PBCRs) in 10 provinces in collaboration with the International Agency for Research on Cancer. This initiative was successful and registry programs became popular among researchers and research centers and created several national and international collaborations in different areas to answer important public health and clinical questions. In this paper, we report the details of the program and list of registries that were granted in the first round.
    MeSH term(s) Biomedical Research/standards ; Humans ; Iran/epidemiology ; Neoplasms/epidemiology ; Program Evaluation/standards ; Public Health ; Registries/statistics & numerical data
    Language English
    Publishing date 2017-11-01
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2204979-4
    ISSN 1735-3947 ; 1029-2977
    ISSN (online) 1735-3947
    ISSN 1029-2977
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6228: Show issues Location:
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