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  1. Article ; Online: Keeping a cut above the coronavirus disease: surgical perspectives from a public health institution in Singapore during Covid-19.

    Ng, Aven Shan Hua / Chew, Min Hoe / Charn, Tze Choong / Wong, Merng Koon / Wong, Wai Keong / Lee, Lui Shiong

    ANZ journal of surgery

    2020  Volume 90, Issue 5, Page(s) 666–669

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Cost of Illness ; Efficiency, Organizational ; Hospital Administration/standards ; Hospitals, Public/standards ; Humans ; Infection Control/organization & administration ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Prevalence ; Public Health/methods ; SARS-CoV-2 ; Singapore/epidemiology ; Workflow
    Keywords covid19
    Language English
    Publishing date 2020-04-21
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.15904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Keeping a cut above the coronavirus disease: surgical perspectives from a public health institution in Singapore during Covid-19

    Ng, Aven Shan Hua / Chew, Min Hoe / Charn, Tze Choong / Wong, Merng Koon / Wong, Wai Keong / Lee, Lui Shiong

    ANZ J Surg

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32274842
    Database COVID19

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  3. Article: Perceptions of healthcare workers in high-risk areas of a Singapore hospital during COVID-19: a cross-sectional study.

    Au-Yong, Phui-Sze Angie / Peh, Wee-Ming / Koh, Frederick Hong-Xiang / Teo, Li-Ming / Ng, Siok-Peng / Tan, Alina Li-Na / Ng, Aven Shan-Hua / Chew, Min-Hoe

    Singapore medical journal

    2021  Volume 63, Issue 9, Page(s) 514–519

    Abstract: Introduction: There is worldwide concern over the psycho-emotional impact of COVID-19 on healthcare workers (HCWs). This study aimed to elicit HCWs' perceptions of the adequacy of protective measures in high-risk clinical areas and the factors ... ...

    Abstract Introduction: There is worldwide concern over the psycho-emotional impact of COVID-19 on healthcare workers (HCWs). This study aimed to elicit HCWs' perceptions of the adequacy of protective measures in high-risk clinical areas and the factors associated with these perceptions.
    Methods: This was a cross-sectional study conducted in April 2020. An anonymous electronic survey was sent via email to operating theatre (OT) and intensive care unit (ICU) staff of Sengkang General Hospital, Singapore.
    Results: Of the 358 eligible participants, 292 (81.6%) responded to the survey. 93.2% of the participants felt that precautionary measures at work were sufficient and 94.9% acknowledged that adequate training was provided. More than 60% of the participants opined that their chances of contracting COVID-19 were moderate to high. Female gender, nursing occupation and duration of service <10 years were significantly associated with increased fear of contracting COVID-19, less control over occupational exposure and lower perceived need to care for COVID-19 patients. Having young children at home did not significantly affect these perceptions. The most important ICU precautions were availability of personal protective equipment outside the rooms of COVID-19 positive patients (95.3%) and having visitor restrictions (95.3%). The most important OT measures were having a dedicated OT for COVID-19 positive patients (91.2%) and having simulation as part of protocol familiarisation (91.7%).
    Conclusion: Overall, there was high confidence in the adequacy of COVID-19 protective measures to prevent healthcare transmission in Singapore. The pandemic had a lower degree of psycho-emotional impact on HCWs here as compared to other countries.
    MeSH term(s) Child ; Humans ; Female ; Child, Preschool ; COVID-19/epidemiology ; Cross-Sectional Studies ; SARS-CoV-2 ; Singapore/epidemiology ; Health Personnel/psychology ; Hospitals
    Language English
    Publishing date 2021-09-19
    Publishing country India
    Document type Journal Article
    ZDB-ID 604319-7
    ISSN 0037-5675
    ISSN 0037-5675
    DOI 10.11622/smedj.2021046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Keeping a cut above the coronavirus disease

    Ng, Aven Shan Hua / Chew, Min Hoe / Charn, Tze Choong / Wong, Merng Koon / Wong, Wai Keong / Lee, Lui Shiong

    ANZ Journal of Surgery

    surgical perspectives from a public health institution in Singapore during Covid ‐19

    2020  Volume 90, Issue 5, Page(s) 666–669

    Keywords Surgery ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 390816-1
    ISSN 0004-8682 ; 1445-1433
    ISSN 0004-8682 ; 1445-1433
    DOI 10.1111/ans.15904
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men.

    Le Bert, Nina / Chia, Wan Ni / Wan, Wei Yee / Teo, Alvin Kuo Jing / Chong, Samuel Zeng-Rong / Tan, Nicole / Tan, Doreen Soek Chin / Chia, Adeline / Tan, Iain Beehuat / Kunasegaran, Kamini / Chua, Qin Xuan / Abdad, Mohammad Yazid / Ng, Aven Shan Hua / Vasoo, Shawn / Ang, Julian Xiao-Li / Lee, Mao Sheng / Sun, Louisa / Fang, Jinyan / Zhu, Feng /
    Cook, Alex R / Aw, Tar Choon / Huang, Jingxiang / Tam, Clarence / Lee, Fong Sin / Clapham, Hannah / Goh, Enan Jun-Kang / Peou, Monica Socheata Suor / Tan, Shiow Pin / Ong, Siew Kim / Wang, Lin-Fa / Bertoletti, Antonio / Hsu, Li Yang / Ong, Biauw Chi

    Emerging microbes & infections

    2021  Volume 10, Issue 1, Page(s) 2141–2150

    Abstract: Background: We studied humoral and cellular responses against SARS-CoV-2 longitudinally in a homogeneous population of healthy young/middle-aged men of South Asian ethnicity with mild COVID-19.: Methods: In total, we recruited 994 men (median age: 34 ...

    Abstract Background: We studied humoral and cellular responses against SARS-CoV-2 longitudinally in a homogeneous population of healthy young/middle-aged men of South Asian ethnicity with mild COVID-19.
    Methods: In total, we recruited 994 men (median age: 34 years) post-COVID-19 diagnosis. Repeated cross-sectional surveys were conducted between May 2020 and January 2021 at six time points - day 28 (
    Results: All serological tests displayed different kinetics of progressive antibody reduction while the frequency of T cells specific for different structural SARS-CoV-2 proteins was stable over time. Both showed a marked heterogeneity of magnitude among the studied cohort. Comparatively, cellular responses lasted longer than humoral responses and were still detectable nine months after infection in the individuals who lost antibody detection. Correlation between T cell frequencies and all antibodies was lost over time.
    Conclusion: Humoral and cellular immunity against SARS-CoV-2 is induced with differing kinetics of persistence in those with mild disease. The magnitude of T cells and antibodies is highly heterogeneous in a homogeneous study population. These observations have implications for COVID-19 surveillance, vaccination strategies, and post-pandemic planning.
    MeSH term(s) Adult ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; COVID-19/immunology ; Cross-Sectional Studies ; Humans ; Male ; Nucleocapsid Proteins/immunology ; SARS-CoV-2/immunology ; T-Lymphocytes/immunology
    Chemical Substances Antibodies, Neutralizing ; Antibodies, Viral ; Nucleocapsid Proteins
    Language English
    Publishing date 2021-10-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2681359-2
    ISSN 2222-1751 ; 2222-1751
    ISSN (online) 2222-1751
    ISSN 2222-1751
    DOI 10.1080/22221751.2021.1999777
    Database MEDical Literature Analysis and Retrieval System OnLINE

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