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  1. Article ; Online: Can we trust ECG for diagnosing hyperkalemia? A challenging question for clinicians and bioengineers.

    Regolisti, Giuseppe / Rossi, Giovanni Maria / Genovesi, Simonetta

    International journal of cardiology

    2023  Volume 393, Page(s) 131380

    Language English
    Publishing date 2023-09-22
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2023.131380
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  2. Article: Diagnostic Imaging of Agminated Blue Lesions and Blue Lesions with Satellitosis: Case Series with a Concise Review of the Current Literature.

    Cantisani, Carmen / Paolino, Giovanni / Di Guardo, Antonio / Gomes, Vito / Carugno, Andrea / Greco, Maria Elisabetta / Musolff, Noah / Azzella, Giulia / Rossi, Giovanni / Soda, Giuseppe / Longo, Caterina / Pellacani, Giovanni

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030894
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  3. Article ; Online: Volumetric analysis in primary and residual type B aortic dissection treated with stented-assisted balloon-induced intimal disruption and relamination (STABILISE) technique can predict aortic reintervention.

    Ferraresi, Marco / Molinari, Alessandro Carlo Luigi / Katsarou, Maria / Rossi, Giovanni

    Journal of vascular surgery

    2024  

    Abstract: Objective: The aim of this study was to investigate the mid-term results of stented-assisted balloon-induced intimal disruption and relamination (STABILISE) in patients with aortic dissection with the implementation of volumetric analysis.: Methods: ... ...

    Abstract Objective: The aim of this study was to investigate the mid-term results of stented-assisted balloon-induced intimal disruption and relamination (STABILISE) in patients with aortic dissection with the implementation of volumetric analysis.
    Methods: This was a single-center retrospective analysis of prospectively collected data. From May 2017 to September 2022, 42 patients underwent STABILISE for acute complicated or subacute high-risk aortic dissection. STABILISE was completed with distal extended endovascular aortic repair in 24 patients. A computed tomography scan was performed at baseline, before hospital discharge, and at 1, 3, and 5 years. Perfused total aortic, true lumen, and false lumen volumes were assessed for thoracic, visceral, and aorto-iliac segment. The ratio between false lumen and total volume was named perfusion dissection index (PDI). Complete remodeling was defined as PDI = 0, and positive remodeling as PDI ≤0.1.
    Results: Technical success was 97.6%. No 30-day deaths, spinal cord injuries, or retrograde dissections were observed. Mean follow-up was 44 ± 19.4 months. Thoracic diameter was lower at last available computed tomography scan (36.7 vs 33.0 mm; P = .01). Aortic growth >5 mm was observed in 9.5% of the patients. Thoracic and visceral aortic complete remodeling were 92.8% and 83.3%, respectively, with no difference between acute and subacute group. Distal extended endovascular aortic repair significantly increased complete remodeling in the aorto-iliac segment, compared with STABILISE alone (69.6% vs 21.4%; P < .001). Freedom from vascular reinterventions at 3 years was 83.1% (95% confidence interval, 71.5%-96.6%). Total PDI ≤0.1 at first postoperative control was a predictor of vascular reinterventions (P < .0001).
    Conclusions: STABILISE is a safe and feasible technique associated with high mid-term rates of complete remodeling in the thoracic and visceral aorta. Volumetric analysis allows the quantification of aortic remodeling and represents a predictor of aortic reinterventions.
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2024.02.017
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  4. Article: Endovascular repair of ascending aortic pathologies in patients unfit for open surgery: case series and literature review.

    Ferraresi, Marco / Katsarou, Maria / Luigi Molinari, Alessandro Carlo / Segreti, Sara / Rossi, Giovanni

    Journal of vascular surgery cases and innovative techniques

    2024  Volume 10, Issue 3, Page(s) 101455

    Abstract: The number of vascular centers performing endovascular repair of ascending aortic disease is constantly increasing. Accordingly to the guidelines, open surgical repair remains the gold standard for these pathologies. However, approximately one quarter of ...

    Abstract The number of vascular centers performing endovascular repair of ascending aortic disease is constantly increasing. Accordingly to the guidelines, open surgical repair remains the gold standard for these pathologies. However, approximately one quarter of patients are deemed unfit for open surgery. In this study, we describe three cases of ascending thoracic endovascular aortic repair (TEVAR) performed at our center. All the patients were deemed unfit for open surgery by the aortic team. Two patients had an ascending aortic pseudoaneurysm, and the third had a focal type A aortic dissection. In two cases, we used two abdominal aortic cuffs deployed from zone 0B to zone 0C, with no need for supra-aortic trunk debranching. In one case, we performed a "reverse" extrathoracic debranching, and we deployed a thoracic endograft from zone 0B to zone 2. Complications included one minor stroke and one inguinal hematoma. In one patient with an infected pseudoaneurysm, we performed ascending TEVAR as a bridge strategy for open repair. This patient developed a type Ia endoleak; however, clinical stabilization and infection control were obtained, and he was able to undergo heart surgery successfully. He underwent a second reintervention to treat superior mesenteric embolic occlusion. At 2 years of follow-up, all three patients were alive. Our preliminary experience demonstrates the technical feasibility and clinical appropriateness of ascending TEVAR using standard, commercially available endografts. However, no consensus has been reached regarding some critical aspects, such as the development of a standardized technique or the efficacy of the currently available devices. The improvements in graft design and the adoption of the "aortic team" approach could help in the near future to standardize the procedure, establish appropriate indications, and ensure good clinical outcomes.
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ISSN 2468-4287
    ISSN 2468-4287
    DOI 10.1016/j.jvscit.2024.101455
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  5. Article ; Online: Recent advances in intestinal fibrosis.

    Lenti, Marco Vincenzo / Santacroce, Giovanni / Broglio, Giacomo / Rossi, Carlo Maria / Di Sabatino, Antonio

    Molecular aspects of medicine

    2024  Volume 96, Page(s) 101251

    Abstract: Despite many progresses have been made in the treatment of inflammatory bowel disease, especially due to the increasing number of effective therapies, the development of tissue fibrosis is a very common occurrence along the natural history of this ... ...

    Abstract Despite many progresses have been made in the treatment of inflammatory bowel disease, especially due to the increasing number of effective therapies, the development of tissue fibrosis is a very common occurrence along the natural history of this condition. To a certain extent, fibrogenesis is a physiological and necessary process in all those conditions characterised by chronic inflammation. However, the excessive deposition of extracellular matrix within the bowel wall will end up in the formation of strictures, with the consequent need for surgery. A number of mechanisms have been described in this process, but some of them are not yet clear. For sure, the main trigger is the presence of a persistent inflammatory status within the mucosa, which in turn favours the occurrence of a pro-fibrogenic environment. Among the main key players, myofibroblasts, fibroblasts, immune cells, growth factors and cytokines must be mentioned. Although there are no available therapies able to target fibrosis, the only way to prevent it is by controlling inflammation. In this review, we summarize the state of art of the mechanisms involved in gut fibrogenesis, how to diagnose it, and which potential targets could be druggable to tackle fibrosis.
    MeSH term(s) Humans ; Crohn Disease/metabolism ; Crohn Disease/pathology ; Intestines ; Fibroblasts/metabolism ; Inflammation/metabolism ; Fibrosis
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 197640-0
    ISSN 1872-9452 ; 0098-2997
    ISSN (online) 1872-9452
    ISSN 0098-2997
    DOI 10.1016/j.mam.2024.101251
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    Zs.A 1189: Show issues Location:
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  6. Article ; Online: Predicting hyperkalemia in patients with acute kidney injury: time for a change of weaponry.

    Bianchi, Stefano / Rossi, Giovanni Maria

    Internal and emergency medicine

    2019  Volume 15, Issue 3, Page(s) 371–372

    MeSH term(s) Acute Kidney Injury ; Arrhythmias, Cardiac ; Electrocardiography ; Humans ; Hyperkalemia
    Language English
    Publishing date 2019-12-03
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-019-02245-7
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  7. Article ; Online: Gender, Obesity, Fat Distribution and 25-Hydroxyvitamin D.

    Guagnano, Maria Teresa / D'Ardes, Damiano / Di Giovanni, Pamela / Rossi, Ilaria / Boccatonda, Andrea / Bucci, Marco / Cipollone, Francesco

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 6

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Adult ; Humans ; Male ; Middle Aged ; Overweight/complications ; Overweight/epidemiology ; Vitamin D Deficiency/complications ; Body Mass Index ; Obesity/complications ; Vitamin D ; Calcifediol
    Chemical Substances 25-hydroxyvitamin D (A288AR3C9H) ; Vitamin D (1406-16-2) ; Calcifediol (P6YZ13C99Q)
    Language English
    Publishing date 2023-06-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59061123
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  8. Article ; Online: Regression Models to Study the Total LOS Related to Valvuloplasty.

    Scala, Arianna / Trunfio, Teresa Angela / De Coppi, Lucia / Rossi, Giovanni / Borrelli, Anna / Triassi, Maria / Improta, Giovanni

    International journal of environmental research and public health

    2022  Volume 19, Issue 5

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Aged ; Cardiac Surgical Procedures ; Heart Failure ; Humans ; Italy ; Length of Stay ; Mitral Valve Insufficiency
    Language English
    Publishing date 2022-03-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19053117
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  9. Article: Morphological and Genetic Characterization of Maize Landraces Adapted to Marginal Hills in North-West Italy.

    Di Pasquale, Giovanni Maria / Stagnati, Lorenzo / Lezzi, Alessandra / Lanubile, Alessandra / Marocco, Adriano / Rossi, Graziano / Busconi, Matteo

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 7

    Abstract: The growing interest in maize landraces over the past two decades has led to the need to characterize the Italian maize germplasm. In Italy, hundreds of maize landraces have been developed, but only a few of them have been genetically characterized, and ... ...

    Abstract The growing interest in maize landraces over the past two decades has led to the need to characterize the Italian maize germplasm. In Italy, hundreds of maize landraces have been developed, but only a few of them have been genetically characterized, and even fewer are currently employed in agriculture or for breeding purposes. In the present study, 13 maize landraces of the west Emilia-Romagna region were morphologically and genetically characterized. These accessions were sampled in 1954 from three provinces, Modena, Parma, and Piacenza, during the characterization project of Italian maize landraces. The morphological characterization of these 13 accessions was performed according to the UPOV protocol CPVO/TP2/3, examining 34 phenotypic traits. A total of 820 individuals were genotyped with 10 SSR markers. The genetic characterization revealed 74 different alleles, a F
    Language English
    Publishing date 2024-04-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13071030
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  10. Article ; Online: Thrombotic microangiopathy due to primary antiphospholipid syndrome: successful treatment with eculizumab.

    Pala, Chiara / Parenti, Elisabetta / Vizzini, Giuseppe / Gianfreda, Davide / Rossi, Giovanni Maria

    Journal of nephrology

    2023  

    Abstract: Antiphospholipid syndrome nephropathy includes a variety of histological lesions, including thrombotic microangiopathy, which is not included among the diagnostic criteria of antiphospholipid syndrome. Whereas in secondary antiphospholipid syndrome, e.g. ...

    Abstract Antiphospholipid syndrome nephropathy includes a variety of histological lesions, including thrombotic microangiopathy, which is not included among the diagnostic criteria of antiphospholipid syndrome. Whereas in secondary antiphospholipid syndrome, e.g. to systemic lupus erythematosus, there is emerging evidence of a benefit from complement blockade with eculizumab, optimal treatment of primary antiphospholipid syndrome-associated thrombotic microangiopathy is currently unknown. We report the case of a 36-year-old male patient with primary antiphospholipid syndrome-associated thrombotic microangiopathy, presenting with a clinical picture of atypical hemolytic-uremic syndrome with frequent relapses, treated with eculizumab (four 900 mg weekly doses followed by 1200 mg fortnightly infusions) leading to resolution of hemolysis, long-term remission and partial kidney function recovery (peak serum creatinine 3.8 mg/dL, decreased and stabilized around 2.5 mg/dL) over a follow up period of over 2 years.
    Language English
    Publishing date 2023-10-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-023-01789-4
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