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  1. Book: Schrier's diseases of the kidney / 1

    Coffman, Thomas M. / Schrier, Robert W.

    2013  

    Author's details ed. by Thomas M. Coffman
    Collection Schrier's diseases of the kidney
    Language English
    Size XXV, 1259, 151 S. : Ill., graph. Darst.
    Publisher Wolters Kluwer Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Accompanying material Zugang zu zusätzlichem Internetmaterial über Code
    HBZ-ID HT017432092
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 8720 order for loan Magazin
    Zugang zu zusätzlichem Internetmaterial über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  2. Book: Schrier's diseases of the kidney / 2

    Coffman, Thomas M. / Schrier, Robert W.

    2013  

    Author's details ed. by Thomas M. Coffman
    Collection Schrier's diseases of the kidney
    Language English
    Size XXV, 151 S., S. 1260 - 2603 : Ill., graph. Darst.
    Publisher Wolters Kluwer Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017432108
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 8721 order for loan Magazin

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  3. Book ; Collection: Schrier's diseases of the kidney

    Coffman, Thomas M. / Schrier, Robert W.

    2013  

    Title variant Diseases of the kidney
    Author's details ed. by Thomas M. Coffman
    Keywords Kidney Diseases
    Language English
    Dates of publication 2013-9999
    Edition 9. ed.
    Publisher Wolters Kluwer Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book ; Collection (display volumes)
    Note Rev. ed. of: Diseases of the kidney & urinary tract. c2007 ; Includes bibliographical references and index
    HBZ-ID HT017432059
    ISBN 978-1-4511-1075-3 ; 1-4511-1075-8
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Kidney Renin-Angiotensin System: Lost in a RAS Cascade.

    Crowley, Steven D / Navar, L Gabriel / Prieto, Minolfa C / Gurley, Susan B / Coffman, Thomas M

    Hypertension (Dallas, Tex. : 1979)

    2024  Volume 81, Issue 4, Page(s) 682–686

    Abstract: Renin was discovered more than a century ago. Since then, the functions of the renin-angiotensin system in the kidney have been the focus of intensive research revealing its importance in regulation of renal physiology and in the pathogenesis of heart, ... ...

    Abstract Renin was discovered more than a century ago. Since then, the functions of the renin-angiotensin system in the kidney have been the focus of intensive research revealing its importance in regulation of renal physiology and in the pathogenesis of heart, vascular, and kidney diseases. Inhibitors of renin-angiotensin system components are now foundational therapies for a range of kidney and cardiovascular diseases from hypertension to heart failure to diabetic nephropathy. Despite years of voluminous research, emerging studies continue to reveal new complexities of the regulation of the renin-angiotensin system within the kidney and identification of nonclassical components of the system like the prorenin receptor (PRR) and ACE2 (angiotensin-converting enzyme 2), with powerful renal effects that ultimately impact the broader cardiovascular system. With the emergence of a range of novel therapies for cardiovascular and kidney diseases, the importance of a detailed understanding of the renin-angiotensin system in the kidney will allow for the development of informed complementary approaches for combinations of treatments that will optimally promote health and longevity over the century ahead.
    MeSH term(s) Humans ; Renin-Angiotensin System ; Health Promotion ; Kidney/metabolism ; Hypertension ; Renin/metabolism ; Diabetic Nephropathies/metabolism
    Chemical Substances Renin (EC 3.4.23.15)
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.123.21367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1488: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Oliver Smithies: A Remembrance.

    Coffman, Thomas M

    Hypertension (Dallas, Tex. : 1979)

    2017  Volume 70, Issue 1, Page(s) 3–4

    Language English
    Publishing date 2017-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.117.09118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1488: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: Pathophysiology of Hypertension: The Mosaic Theory and Beyond.

    Harrison, David G / Coffman, Thomas M / Wilcox, Christopher S

    Circulation research

    2021  Volume 128, Issue 7, Page(s) 847–863

    Abstract: Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end-organ damage. Over the years, Dr Page modified his paradigm, and new ... ...

    Abstract Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end-organ damage. Over the years, Dr Page modified his paradigm, and new concepts regarding oxidative stress, inflammation, genetics, sodium homeostasis, and the microbiome have arisen that allow further refinements of the Mosaic Theory. A constant feature of this approach to understanding hypertension is that the various nodes are interdependent and that these almost certainly vary between experimental models and between individuals with hypertension. This review discusses these new concepts and provides an introduction to other reviews in this compendium of
    MeSH term(s) Aldosterone/physiology ; Angiotensin II/pharmacology ; Blood Pressure/drug effects ; Blood Pressure/physiology ; Blood Vessels/physiology ; Body Fluids/physiology ; Central Nervous System/physiology ; Humans ; Hypertension/etiology ; Hypertension/physiopathology ; Inflammation/complications ; Kidney/physiology ; Microbiota/physiology ; Reactive Oxygen Species/metabolism ; Risk Factors ; Sodium Chloride/administration & dosage ; Sodium Chloride/adverse effects ; Vasoconstrictor Agents/pharmacology
    Chemical Substances Reactive Oxygen Species ; Vasoconstrictor Agents ; Angiotensin II (11128-99-7) ; Sodium Chloride (451W47IQ8X) ; Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2021-04-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.121.318082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui IV Zs.70: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)
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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: The inextricable role of the kidney in hypertension.

    Coffman, Thomas M

    The Journal of clinical investigation

    2014  Volume 124, Issue 6, Page(s) 2341–2347

    Abstract: An essential link between the kidney and blood pressure control has long been known. Here, we review evidence supporting the premise that an impaired capacity of the kidney to excrete sodium in response to elevated blood pressure is a major contributor ... ...

    Abstract An essential link between the kidney and blood pressure control has long been known. Here, we review evidence supporting the premise that an impaired capacity of the kidney to excrete sodium in response to elevated blood pressure is a major contributor to hypertension, irrespective of the initiating cause. In this regard, recent work suggests that novel pathways controlling key sodium transporters in kidney epithelia have a critical impact on hypertension pathogenesis, supporting a model in which impaired renal sodium excretion is a final common pathway through which vascular, neural, and inflammatory responses raise blood pressure. We also address recent findings calling into question long-standing notions regarding the relationship between sodium intake and changes in body fluid volume. Expanded understanding of the role of the kidney as both a cause and target of hypertension highlights key aspects of pathophysiology and may lead to identification of new strategies for prevention and treatment.
    MeSH term(s) Aldosterone/physiology ; Animals ; Blood Pressure/immunology ; Blood Pressure/physiology ; Homeostasis ; Humans ; Hypertension/etiology ; Hypertension/physiopathology ; Kidney/immunology ; Kidney/physiopathology ; Models, Biological ; Protein Serine-Threonine Kinases/physiology ; Renin-Angiotensin System/physiology ; Sodium/metabolism
    Chemical Substances Aldosterone (4964P6T9RB) ; Sodium (9NEZ333N27) ; Protein Serine-Threonine Kinases (EC 2.7.11.1)
    Language English
    Publishing date 2014-06-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/JCI72274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.184: Show issues Location:
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  8. Article ; Online: Angiotensin II Type 1A Receptor Expressed in Smooth Muscle Cells is Required for Hypertensive Vascular Remodeling in Mice Infused With Angiotensin II.

    Okuno, Keisuke / Torimoto, Keiichi / Cicalese, Stephanie M / Preston, Kyle / Rizzo, Victor / Hashimoto, Tomoki / Coffman, Thomas M / Sparks, Matthew A / Eguchi, Satoru

    Hypertension (Dallas, Tex. : 1979)

    2023  Volume 80, Issue 3, Page(s) 668–677

    Abstract: Background: Ang II (angiotensin II) type 1 (AT: Methods: About 1 µg/kg per minute Ang II was infused for 2 weeks in 2 distinct AT: Results: Medial thickness, adventitial collagen deposition, and immune cell infiltration in aorta were increased in ... ...

    Abstract Background: Ang II (angiotensin II) type 1 (AT
    Methods: About 1 µg/kg per minute Ang II was infused for 2 weeks in 2 distinct AT
    Results: Medial thickness, adventitial collagen deposition, and immune cell infiltration in aorta were increased in control mice but not in both smooth muscle AT
    Conclusions: Smooth muscle AT
    MeSH term(s) Mice ; Animals ; Receptor, Angiotensin, Type 1/genetics ; Angiotensin II/pharmacology ; Vascular Remodeling ; Hypertension ; Myocytes, Smooth Muscle ; Cardiomegaly ; Fibrosis ; Mice, Knockout ; Mice, Inbred C57BL
    Chemical Substances Receptor, Angiotensin, Type 1 ; Angiotensin II (11128-99-7)
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.122.20601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1488: Show issues Location:
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  9. Article: Gratitude Conversations: An Experimental Trial of an Online Parenting Tool.

    Hussong, Andrea M / Coffman, Jennifer L / Thomas, Taylor E

    The journal of positive psychology

    2019  Volume 15, Issue 2, Page(s) 267–277

    Abstract: Gratitude is associated with a host of positive outcomes; yet, little is understood about the ways in which parents may foster gratitude in their children. The current study allows for the examination of one possible mechanism, namely parent-child ... ...

    Abstract Gratitude is associated with a host of positive outcomes; yet, little is understood about the ways in which parents may foster gratitude in their children. The current study allows for the examination of one possible mechanism, namely parent-child conversations, that may be used to encourage gratitude in children. Using a rigorous experimental design, we tested whether an online program that was designed to enrich parents' skills in having conversations about gratitude with their children was effective in changing parents' socialization behaviors and children's gratitude. Results demonstrated that parents can successfully utilize an online program to enhance their gratitude-related communication. This training permeates other aspects of how parents socialize gratitude in children and positively impacts children's gratitude moments. Implications for program development and understanding the role of parents in the development of children's gratitude are discussed.
    Language English
    Publishing date 2019-05-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2234160-2
    ISSN 1743-9779 ; 1743-9760
    ISSN (online) 1743-9779
    ISSN 1743-9760
    DOI 10.1080/17439760.2019.1610484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: In the Wake of Systolic Blood Pressure Intervention Trial: New Targets for Improving Hypertension Management in Chronic Kidney Disease?

    Tyson, Crystal C / Coffman, Thomas M

    Nephron

    2017  Volume 135, Issue 4, Page(s) 287–290

    Abstract: Systolic Blood Pressure Intervention Trial (SPRINT) was a multicenter randomized controlled trial showing the significant benefit of intensive reduction of blood pressure to a target of 120 mm Hg in individuals with hypertension and elevated ... ...

    Abstract Systolic Blood Pressure Intervention Trial (SPRINT) was a multicenter randomized controlled trial showing the significant benefit of intensive reduction of blood pressure to a target of 120 mm Hg in individuals with hypertension and elevated cardiovascular risk. Because SPRINT includes the largest cohort of adults with chronic kidney disease (CKD) to be prospectively studied in a hypertension intervention trial, it has particular relevance to the field of nephrology. Here, we review the findings of SPRINT and assess their potential impact on guidelines for treatment of hypertension in patients with CKD. We believe that the data from SPRINT will support a recommendation for lowering blood pressure targets to 120 mm Hg in a substantial segment of adults with CKD.
    MeSH term(s) Adult ; Antihypertensive Agents/therapeutic use ; Blood Pressure/drug effects ; Cardiovascular Diseases/complications ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/physiopathology ; Humans ; Hypertension/complications ; Hypertension/drug therapy ; Hypertension/physiopathology ; Practice Guidelines as Topic ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/drug therapy ; Renal Insufficiency, Chronic/physiopathology ; Risk Factors
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2017
    Publishing country Switzerland
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 207121-6
    ISSN 2235-3186 ; 1423-0186 ; 1660-8151 ; 0028-2766
    ISSN (online) 2235-3186 ; 1423-0186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000455130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 169: Show issues Location:
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