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  1. Article ; Online: Hepatobiliary Scintigraphy to Increase the Safety in Right Lobe Living Donor Liver Transplantation: Not Just a Matter of Age and Remnant Volume.

    Serenari, Matteo / Ravaioli, Matteo / Cescon, Matteo

    Transplantation

    2021  Volume 105, Issue 6, Page(s) e63

    MeSH term(s) Hepatectomy ; Humans ; Liver/diagnostic imaging ; Liver Transplantation/adverse effects ; Living Donors ; Radionuclide Imaging
    Language English
    Publishing date 2021-05-28
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000003658
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  2. Article: Refining selection criteria to further increase survival benefit in liver transplantation for unresectable colorectal liver metastases.

    Serenari, Matteo / Ravaioli, Matteo

    Hepatobiliary surgery and nutrition

    2019  Volume 9, Issue 4, Page(s) 490–492

    Keywords covid19
    Language English
    Publishing date 2019-09-26
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn.2019.11.10
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  3. Article ; Online: Reply to: "Impact of MELD 30-allocation policy on liver transplant outcomes in Italy: Considerations".

    Sessa, Maurizio / Lai, Quirino / Germinario, Giuliana / Ravaioli, Matteo

    Journal of hepatology

    2022  Volume 77, Issue 2, Page(s) 573–574

    Language English
    Publishing date 2022-05-07
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2022.04.034
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    Zs.A 2027: Show issues Location:
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  4. Article ; Online: The Importance of Multiorgan Procurement in the Improvement of Residents' Open Surgical Skills.

    Serenari, Matteo / Lenzi, Jacopo / Ricci, Claudio / Odaldi, Federica / Maroni, Lorenzo / Laurenzi, Andrea / Prosperi, Enrico / Bonatti, Chiara / Fallani, Guido / Caputo, Francesca / Rottoli, Matteo / Ravaioli, Matteo / Cescon, Matteo

    The Journal of surgical research

    2024  Volume 296, Page(s) 441–446

    Abstract: Introduction: The multiorgan procurement (MOP) represents a chance for the general surgery resident to learn the fundamental steps of open abdominal surgery. The objective of this study was to evaluate the impact of MOP on the residents' open surgical ... ...

    Abstract Introduction: The multiorgan procurement (MOP) represents a chance for the general surgery resident to learn the fundamental steps of open abdominal surgery. The objective of this study was to evaluate the impact of MOP on the residents' open surgical skills.
    Methods: Residents' surgical skills were assessed during a 6-month transplant rotation (October 2020-March 2021) using a modified Objective Structured Assessment of Technical Skills with the global rating scale. The surgeries were self-assessed by residents and tutors based on 9 specific steps (SS) and 4 general skills (GS). Each item was rated from 1 (poor) to 5 (excellent) with a maximum score of 45 points for SS and 20 for GS. A crossed-effects linear regression analysis was performed both to evaluate any associations between GS/SS scores and some prespecified covariates, and to study differences in the assessments performed by residents and tutors.
    Results: Residents actively participated in a total of 59 procurements. In general, there were no significant differences in SS/GS mean scorings between residents (n = 15) and tutors (n = 5). There was a significantly positive association between mean GS/SS scorings and the number of donor surgeries performed (at least 5). Comparing the evaluations of the tutors with the residents, this significance was retained only when scorings were assigned by the tutors.
    Conclusions: MOP was shown to improve basic open surgical skills among residents. Awareness of the utility of a clinical rotation in transplant surgery should be raised also on an institutional level.
    MeSH term(s) Internship and Residency ; Clinical Competence ; Abdomen ; Learning ; Transplants ; General Surgery/education
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80170-7
    ISSN 1095-8673 ; 0022-4804
    ISSN (online) 1095-8673
    ISSN 0022-4804
    DOI 10.1016/j.jss.2024.01.012
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    Zs.A 178: Show issues Location:
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  5. Article: Liver Transplantation in Patients with Portal Vein Thrombosis: Revisiting Outcomes According to Surgical Techniques.

    Pinelli, Domenico / Cescon, Matteo / Ravaioli, Matteo / Neri, Flavia / Amaduzzi, Annalisa / Serenari, Matteo / Carioli, Greta / Siniscalchi, Antonio / Colledan, Michele

    Journal of clinical medicine

    2023  Volume 12, Issue 7

    Abstract: Surgical strategies for graft portal vein flow restoration vary from termino-terminal portal vein anastomosis to more complex bypass reconstructions. Although the surgical strategy strongly influences the post-operative outcome, the Yerdel grading is ... ...

    Abstract Surgical strategies for graft portal vein flow restoration vary from termino-terminal portal vein anastomosis to more complex bypass reconstructions. Although the surgical strategy strongly influences the post-operative outcome, the Yerdel grading is still commonly used to determine the prognosis of patients with portal vein thrombosis (PVT) undergoing liver transplantation (LT). We retrospectively reviewed the cases of LT performed on recipients with complex PVT at two high-volume transplantation centres. We stratified the patients by the type of portal vein reconstruction, termino-terminal portal vein anastomosis (TTA) versus bypass reconstruction (bypass group), and assessed a multivariable survival analysis. The rate of mortality at 90 days was 21.4% for the bypass group compared to 9.8% in the TTA group (
    Language English
    Publishing date 2023-03-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12072457
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  6. Article ; Online: Reply.

    Dondossola, Daniele / Ravaioli, Matteo / Germinario, Giuliana / Cescon, Matteo / Rossi, Giorgio

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2021  Volume 27, Issue 11, Page(s) 1684–1685

    MeSH term(s) Brain Death ; Humans ; Liver Transplantation ; Perfusion
    Language English
    Publishing date 2021-08-01
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1002/lt.26211
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    Zs.A 4702: Show issues Location:
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  7. Article ; Online: Surgical management of hepatocellular carcinoma-Western versus Eastern attitude.

    Neri, Flavia / Maroni, Lorenzo / Ravaioli, Matteo

    Translational cancer research

    2022  Volume 8, Issue Suppl 3, Page(s) S245–S260

    Abstract: Hepatocellular carcinoma (HCC) is the most common liver tumour and represents a significant health burden. The different characteristics of the disease in the various parts of the world, as much as economic and social features, explain only partially the ...

    Abstract Hepatocellular carcinoma (HCC) is the most common liver tumour and represents a significant health burden. The different characteristics of the disease in the various parts of the world, as much as economic and social features, explain only partially the great diversity in the treatment options offered to patients in different countries. The most apparent contrast in term of tumour management is between the western and eastern world. Striking differences involve not only the attitude towards indications for liver transplantation or liver resection but also the surgical techniques adopted. Although remarkable signs of progress have been achieved in surgical and pharmacological fields, univocal guidelines are yet lacking, preventing effective comparisons between retrospective studies and clinical trials. This review aims to analyse and compare some of the most relevant and essential traits of the eastern and western therapeutic strategy against HCC.
    Language English
    Publishing date 2022-01-15
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2901601-0
    ISSN 2219-6803 ; 2218-676X
    ISSN (online) 2219-6803
    ISSN 2218-676X
    DOI 10.21037/tcr.2018.12.28
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  8. Article ; Online: Using Transesophageal Echocardiography in Liver Transplantation with Veno-Venous Bypass Is a Tool with Many Applications: A Case Series from an Italian Transplant Center.

    Bianchini, Amedeo / Laici, Cristiana / Bordini, Martina / Bianchin, Matteo / Silvas, Catalin Iustin Ioan / Cescon, Matteo / Ravaioli, Matteo / Vitale, Giovanni / Siniscalchi, Antonio

    Journal of cardiovascular development and disease

    2023  Volume 10, Issue 1

    Abstract: Background: Hemodynamic instability (HDI) is common during liver transplantation (LT); veno-venous bypass (VVB) is a tool used in selected cases to ensure hemodynamic stability and for surgical needs. Transesophageal echocardiography (TEE) allows the ... ...

    Abstract Background: Hemodynamic instability (HDI) is common during liver transplantation (LT); veno-venous bypass (VVB) is a tool used in selected cases to ensure hemodynamic stability and for surgical needs. Transesophageal echocardiography (TEE) allows the transplant team to identify the causes of HDI and to guide therapies. We present a case series of four patients showing the valuable role of TEE during LT in VVB.
    Methods: We report four explicative cases of TEE use in LT with VVB performed at IRCCS Azienda Ospedaliero-Universitaria di Bologna. Four transplants were performed between 2016 and 2022.
    Results: Many authors have highlighted the diagnostic value of TEE during LT in the case of HDI. However, its specific role during LT with VVB is poorly described. This paper illustrates multiple potential uses of TEE in LT with VVB: TEE as a guide for catheterization and optimal cannula positioning, TEE as a tool for intraoperative Patent Foramen Ovale management, TEE as help for anticoagulation therapy and finally, TEE as support when evaluating bypass efficiency and correcting hypovolemia.
    Conclusion: TEE is a useful instrument during LT with VVB. However, further studies are needed to assess the suitable applications of TEE during LT in patients with HDI requiring VVB. TEE should be part of the anesthetist's cultural background.
    Language English
    Publishing date 2023-01-16
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10010032
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  9. Article: Refining selection criteria to further increase survival benefit in liver transplantation for unresectable colorectal liver metastases

    Serenari, Matteo / Ravaioli, Matteo

    Hepatobiliary Surg Nutr

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32832500
    Database COVID19

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  10. Article ; Online: The role of cold ischemia time and hypothermic perfusion in predicting early hepatocellular carcinoma recurrences after liver transplantation.

    Dajti, Gerti / Germinario, Giuliana / Prosperi, Enrico / Siniscalchi, Antonio / Vasuri, Francesco / Valente, Sabrina / Odaldi, Federica / Maroni, Lorenzo / Serenari, Matteo / Bertuzzo, Valentina / Laurenzi, Andrea / Del Gaudio, Massimo / Cescon, Matteo / Ravaioli, Matteo

    Artificial organs

    2024  

    Abstract: Aim: The aim of the study was to identify predictors of early tumor recurrence in patients with hepatocellular carcinoma (HCC) after liver transplantation (LT).: Methods: Retrospective cohort study in 237 consecutive liver recipients with HCC between ...

    Abstract Aim: The aim of the study was to identify predictors of early tumor recurrence in patients with hepatocellular carcinoma (HCC) after liver transplantation (LT).
    Methods: Retrospective cohort study in 237 consecutive liver recipients with HCC between 2016 and 2021. Multivariate logistic analysis was performed to identify predictors of early HCC recurrences. The impact of hypothermic-oxygenated perfusion (HOPE) on outcome was analyzed after propensity score weighting.
    Results: Early recurrences were observed in 15 cases. Microvascular invasion (OR 3.737, 95% CI 1.246-11.206, p = 0.019) and cold ischemia time (OR 1.155, 95% CI 1.001-1.333, p = 0.049) were independently associated with a lower risk of HCC recurrences. After balancing for relevant variables, patients in the HOPE group had lower rates of tumor recurrence (weighted OR 0.126, 95% CI 0.016-0.989, p = 0.049) and higher recurrence free survival (weighted HR 0.132, 95% CI 0.017-0.999, p = 0.050).
    Conclusion: Reducing cold ischemia time and graft perfusion with HOPE can lead to lower rates of early HCC recurrences and higher recurrence-free survival.
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 441812-8
    ISSN 1525-1594 ; 0160-564X
    ISSN (online) 1525-1594
    ISSN 0160-564X
    DOI 10.1111/aor.14715
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