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  1. Article ; Online: Impact of covid-19 vaccination on long covid.

    Edwards, Frances / Hamilton, Fergus W

    BMJ medicine

    2023  Volume 2, Issue 1, Page(s) e000470

    Language English
    Publishing date 2023-02-01
    Publishing country England
    Document type Editorial ; Comment
    ISSN 2754-0413
    ISSN (online) 2754-0413
    DOI 10.1136/bmjmed-2022-000470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tolerance versus resistance to infection in sepsis.

    Hamilton, Fergus

    The Lancet. Infectious diseases

    2020  Volume 20, Issue 3, Page(s) 281

    MeSH term(s) Humans ; Immune Tolerance ; Sepsis ; Translational Medical Research
    Language English
    Publishing date 2020-03-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30045-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5743: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Tracking Progress in Improving Diagnosis: a Framework for Defining Undesirable Diagnostic Events.

    Hamilton, Fergus

    Journal of general internal medicine

    2019  Volume 34, Issue 10, Page(s) 1959

    Language English
    Publishing date 2019-01-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-018-4786-y
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    Zs.A 2205: Show issues Location:
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  4. Article ; Online: Author Correction: An observational and Mendelian randomisation study on iron status and sepsis.

    Hamilton, Fergus / Mitchell, Ruth / Ahmed, Haroon / Ghazal, Peter / Timpson, Nicholas J

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6033

    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56374-x
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  5. Article ; Online: Comment on: "Transgender Women in the Female Category of Sport: Perspectives on Testosterone Suppression and Performance Advantage".

    Hamilton, Blair / Guppy, Fergus / Pitsiladis, Yannis

    Sports medicine (Auckland, N.Z.)

    2023  Volume 54, Issue 1, Page(s) 237–242

    MeSH term(s) Humans ; Female ; Transgender Persons ; Sports ; Testosterone
    Chemical Substances Testosterone (3XMK78S47O)
    Language English
    Publishing date 2023-09-20
    Publishing country New Zealand
    Document type Letter
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.1007/s40279-023-01928-8
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    Zs.A 2010: Show issues Location:
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  6. Article ; Online: Novel Assay of Immunity: Adding More Than Adding Up Steroids?

    Hamilton, Fergus

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2018  Volume 67, Issue 12, Page(s) 1956

    MeSH term(s) Humans ; Immunity ; Steroids ; Transplant Recipients
    Chemical Substances Steroids
    Language English
    Publishing date 2018-06-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciy465
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    Zs.A 1505: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 480: Show issues

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  7. Article ; Online: Extended Follow-up of Microbiome Therapeutic SER-109 for Recurrent Clostridioides difficile Infection.

    Hamilton, Fergus / Wright, William F / Lee, Todd C

    JAMA

    2023  Volume 329, Issue 12, Page(s) 1032–1033

    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Follow-Up Studies ; Clostridioides difficile ; Clostridium Infections/microbiology ; Clostridium Infections/therapy ; Gastrointestinal Microbiome/drug effects ; Probiotics/pharmacology ; Probiotics/therapeutic use ; Recurrence
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2023.0497
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    Ua VI Zs.88: Show issues Location:
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  8. Article ; Online: Letter to the Editor From Richmond et al: "Sleep Duration and Visceral Adipose Tissue: Linear and Nonlinear Mendelian Randomization Analyses".

    Richmond, Rebecca C / Hamilton, Fergus W / Davey Smith, George

    The Journal of clinical endocrinology and metabolism

    2023  Volume 109, Issue 3, Page(s) e1316–e1317

    MeSH term(s) Humans ; Sleep Duration ; Mendelian Randomization Analysis ; Sleep ; Obesity, Abdominal ; Genome-Wide Association Study
    Language English
    Publishing date 2023-10-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgad598
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    Uh III Zs.134: Show issues Location:
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  9. Article ; Online: Bad research is not all bad.

    Hamilton, Fergus / Arnold, David / Lilford, Richard

    Trials

    2023  Volume 24, Issue 1, Page(s) 680

    Abstract: In this commentary, we discuss a recent article in Trials that raised concerns about the number of poorly performed randomised trials in the medical literature and discuss the trials literature more widely. Although we all aim for higher methodological ... ...

    Abstract In this commentary, we discuss a recent article in Trials that raised concerns about the number of poorly performed randomised trials in the medical literature and discuss the trials literature more widely. Although we all aim for higher methodological standards in trials, we argue that (i) the idea that 'most randomised trials are bad', which the recent article concludes is an overly simplistic representation of the situation, and (ii) the suggestion that an increased focus on methodological review during trial development (e.g. ethical boards performing some assessment of the methodologists on a trial), while well meaning, may have negative unintended consequences. We therefore propose that (a) trials should be assessed on their merits and weaknesses, including an assessment of risk of bias but placing that in a wider context; (b) we should recognise that although the methodological conduct of trials is of utmost importance, interventions that aim to improve this could have unintended consequences-such as bureaucracy-that have an overall negative effect; and (c) we should therefore generate an evidence base for policy interventions to improve conduct of trials rather than applying arbitrary rules.
    MeSH term(s) Humans ; Bias ; Randomized Controlled Trials as Topic ; Research Design
    Language English
    Publishing date 2023-10-20
    Publishing country England
    Document type Letter
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-023-07706-1
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  10. Article: The Natural History of Antibiotic-Treated Lower Limb Cellulitis: Analysis of Data Extracted From a Multicenter Clinical Trial.

    Williams, O Martin / Hamilton, Fergus / Brindle, Richard

    Open forum infectious diseases

    2023  Volume 10, Issue 10, Page(s) ofad488

    Abstract: Background: Although cellulitis is a relatively common skin infection, there remains uncertainty about management, particularly the length and route of antimicrobials required. Further information on the symptomatology and biomarker changes associated ... ...

    Abstract Background: Although cellulitis is a relatively common skin infection, there remains uncertainty about management, particularly the length and route of antimicrobials required. Further information on the symptomatology and biomarker changes associated with cellulitis over time would guide clinicians and patients as to the expected natural history.
    Methods: We extracted data from a randomized clinical trial (NCT01876628) of clindamycin as adjunctive therapy in cellulitis to illustrate the evolution of local parameters (pain, swelling, local erythema, and warmth) and the resolution of biomarkers over time.
    Results: Data from 247 individuals with mild to moderate unilateral lower limb cellulitis, who attended at least 1 face-to-face interview following recruitment, were used to examine response dynamics. Although there was a local improvement in swelling, warmth, erythema, and pain by day 5 compared with baseline, some individuals still had evidence of local inflammation at 10 days. Most biomarkers demonstrated a return to normal by day 3, although the initial fall in albumin only returned to baseline by day 10.
    Conclusions: Although there was initial resolution, a significant number of individuals still had local symptoms persisting to day 10 and beyond. Clinicians can use these data to reassure themselves and their patients that ongoing local symptoms and signs after completion of antibiotic treatment do not indicate treatment failure or warrant extension of the initial antibiotic treatment or a change in antibiotic class or mode of administration.
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofad488
    Database MEDical Literature Analysis and Retrieval System OnLINE

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