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  1. Book: Zhongguo yi chuan lun li de zheng ming yu tan suo

    Wang, Yanguang

    The ethical disputes and exploration on ethics of genetics in China

    (Sheng ming ke xue jiao cha yan jiu cong shu)

    2006  

    Title variant Ethical disputes and exploration on ethics of genetics in China
    Author's details Wang Yanguang zhu bian
    Series title Sheng ming ke xue jiao cha yan jiu cong shu
    MeSH term(s) Bioethical Issues ; Genetic Engineering/ethics ; Genetic Techniques/ethics
    Keywords China
    Language Chinese
    Size v, 206 p. :, ill. ;, 24 cm.
    Edition Di 1 ban.
    Publisher Ke xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787030161642 ; 7030161645
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Article: [Research Progressin the Relationship between Interleukin-6 and Intervertebral Disc Degeneration].

    Chen, Jin-Lei / Wang, Shuang / Wang, Ming-Chuan / Wang, Xin

    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

    2023  Volume 45, Issue 1, Page(s) 134–142

    Abstract: Intervertebral disc degeneration (IDD) is one of the main diseases causing low back pain,which seriously affects the quality of life of patients.Recent studies have discovered that interleukin-6 (IL-6) is highly expressed in the tissues and cells of ... ...

    Abstract Intervertebral disc degeneration (IDD) is one of the main diseases causing low back pain,which seriously affects the quality of life of patients.Recent studies have discovered that interleukin-6 (IL-6) is highly expressed in the tissues and cells of degenerative intervertebral disc and is closely related to the occurrence and development of IDD.However,the signaling pathway and role of IL-6 in IDD remain to be understood.Therefore,this article reviews the recent studies about the signaling pathway and role of IL-6 in IDD,aiming to facilitate the clinical work and subsequent research progress.
    MeSH term(s) Humans ; Interleukin-6 ; Intervertebral Disc Degeneration ; Quality of Life ; Peptides
    Chemical Substances Interleukin-6 ; progressin (52012-65-4) ; Peptides
    Language Chinese
    Publishing date 2023-02-27
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 604853-5
    ISSN 1000-503X
    ISSN 1000-503X
    DOI 10.3881/j.issn.1000-503X.14709
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Effect of Yanshen No.1 Recipe on the microinflammatory state in patients with chronic kidney disease.

    Yuan, Guo-Dong / Wang, Ze-Ze / Guo, Ming-Xin / Tan, Jin-Chuan

    Asian journal of surgery

    2024  

    Language English
    Publishing date 2024-01-25
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.01.068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Epidemiological Characteristics and Drug Resistance of Microbial Pathogens of Patients With Silicosis Combined With Pulmonary Infection].

    Su, Ming-Chuan / Wang, Lin-Yao / Wang, Mei-Juan / Qin, Si-Han / Kaderya, Omer / Chen, Peng / Zuo, Hao-Jiang / Xie, Lin-Shen

    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

    2023  Volume 54, Issue 2, Page(s) 411–414

    Abstract: Objective: To investigate the epidemiological characteristics of patients with silicosis combined with pulmonary infection in recent years, to study the distribution and the drug susceptibility of fungal and bacterial pathogens in their sputum samples, ... ...

    Abstract Objective: To investigate the epidemiological characteristics of patients with silicosis combined with pulmonary infection in recent years, to study the distribution and the drug susceptibility of fungal and bacterial pathogens in their sputum samples, and to provide references for the prevention and treatment of silicosis and the appropriate drug use.
    Methods: The clinical data and drug sensitivity test results of patients with silicosis combined with pulmonary infection diagnosed at the Department of Occupational Diseases, West China Fourth Hospital, Sichuan University were retrospectively analyzed.
    Results: A total of 318 patients with silicosis combined with pulmonary infection who received treatment between January 2017 and December 2020 were enrolled. All the patients had positive microorganism test results. All participants were male. Their median age at the time of onset was 51.00 years and the median time of exposure to silica dust at work was 12.40 years. They worked mostly in construction, non-ferrous metal mining, and coal mining. The main types of work they did were pneumatic drilling, coal digging, and mining. The positive detection rates for the first, second and third phases of silicosis were 27.54%, 28.32%, and 32.97%, respectively. A total of 341 strains of fungal and bacterial pathogens were isolated, of which, 54.1% were fungi, including 114 strains (35.8%) of
    Conclusion: Among patients with silicosis combined with pulmonary infection, the incidence of pulmonary infection increases along with the progress of silicosis. Microorganism analysis reveals high detection rates for fungi and the bacteria detected are predominantly gram-negative bacteria. The overall prospect for drug resistance rate was not optimistic.
    MeSH term(s) Humans ; Male ; Female ; Retrospective Studies ; Drug Resistance, Bacterial ; Microbial Sensitivity Tests ; Bacteria ; Pneumonia ; Gram-Negative Bacteria ; Drug Resistance ; Silicosis ; Anti-Bacterial Agents/pharmacology
    Chemical Substances Anti-Bacterial Agents
    Language Chinese
    Publishing date 2023-03-22
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2106840-9
    ISSN 1672-173X
    ISSN 1672-173X
    DOI 10.12182/20230360211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2708: Show issues Location:
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  5. Article ; Online: Three-year hospital-wide pain management system implementation at a tertiary medical center: Pain prevalence analysis.

    Chen, Ming-Chuan / Yeh, Te-Feng / Wu, Chih-Cheng / Wang, Yan-Ru / Wu, Chieh-Liang / Chen, Ruei-Ling / Shen, Ching-Hui

    PloS one

    2023  Volume 18, Issue 4, Page(s) e0283520

    Abstract: We developed a pain management system over a 3-year period. In this project, "Towards a pain-free hospital", we combined evidence-based medicine and medical expertise to develop a series of policies. The intervention mainly included the development of ... ...

    Abstract We developed a pain management system over a 3-year period. In this project, "Towards a pain-free hospital", we combined evidence-based medicine and medical expertise to develop a series of policies. The intervention mainly included the development of standard procedures for inpatient pain management, the implementation of hospital-wide pain medicine education and training, the establishment of a dashboard system to track pain status, and regular audits and feedback. This study aimed to gain an understanding of the changes in the prevalence of pain in inpatients under the care of the pain management system. The subjects of the survey are inpatients over 20 years old, and who had been hospitalized in the general ward for at least 3 days. The patients would be excluded if they were unable to respond to the questions. We randomly selected eligible patients in the general ward. Our trained interviewers visited inpatients to complete the questionnaires designed by our pain care specialists. A total of 3,094 inpatients completed the survey from 2018 to 2020. During the three-year period, the prevalence of pain was 69.5% (2018) (reference), 63.3% (2019) (OR:0.768, p<0.01), and 60.1% (2020) (OR:0.662, p <0.001). The prevalence rates of pain in patients undergoing surgery during the 3-year period were 81.4% (2018), 74.3% (2019), and 68.8% (2020), respectively. As for care-related causes of pain, injection, change in position/chest percussion, and rehabilitation showed a decreasing trend over the 3-year period of study. Our pain management system provided immediate professional pain management, and achieved a good result in the management of acute moderate to severe pain, especially perioperative pain. Studies on pain prevalence and Pain-Free Hospitals are scarce in Asia. With the aid of the policies based on evidence-based medicine and the dashboard information system, from 2018 to 2020, the prevalence of pain has decreased year by year.
    MeSH term(s) Humans ; Young Adult ; Adult ; Pain Management ; Prevalence ; Pain/epidemiology ; Pain/drug therapy ; Analgesics/therapeutic use ; Hospitals, Teaching
    Chemical Substances Analgesics
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0283520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Machine Learning Algorithm Predicts Mortality Risk in Intensive Care Unit for Patients with Traumatic Brain Injury.

    Tu, Kuan-Chi / Tau, Eric Nyam Tee / Chen, Nai-Ching / Chang, Ming-Chuan / Yu, Tzu-Chieh / Wang, Che-Chuan / Liu, Chung-Feng / Kuo, Ching-Lung

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 18

    Abstract: Background: Numerous mortality prediction tools are currently available to assist patients with moderate to severe traumatic brain injury (TBI). However, an algorithm that utilizes various machine learning methods and employs diverse combinations of ... ...

    Abstract Background: Numerous mortality prediction tools are currently available to assist patients with moderate to severe traumatic brain injury (TBI). However, an algorithm that utilizes various machine learning methods and employs diverse combinations of features to identify the most suitable predicting outcomes of brain injury patients in the intensive care unit (ICU) has not yet been well-established.
    Method: Between January 2016 and December 2021, we retrospectively collected data from the electronic medical records of Chi Mei Medical Center, comprising 2260 TBI patients admitted to the ICU. A total of 42 features were incorporated into the analysis using four different machine learning models, which were then segmented into various feature combinations. The predictive performance was assessed using the area under the curve (AUC) of the receiver operating characteristic (ROC) curve and validated using the Delong test.
    Result: The AUC for each model under different feature combinations ranged from 0.877 (logistic regression with 14 features) to 0.921 (random forest with 22 features). The Delong test indicated that the predictive performance of the machine learning models is better than that of traditional tools such as APACHE II and SOFA scores.
    Conclusion: Our machine learning training demonstrated that the predictive accuracy of the LightGBM is better than that of APACHE II and SOFA scores. These features are readily available on the first day of patient admission to the ICU. By integrating this model into the clinical platform, we can offer clinicians an immediate prognosis for the patient, thereby establishing a bridge for educating and communicating with family members.
    Language English
    Publishing date 2023-09-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13183016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Three-year hospital-wide pain management system implementation at a tertiary medical center

    Ming-Chuan Chen / Te-Feng Yeh / Chih-Cheng Wu / Yan-Ru Wang / Chieh-Liang Wu / Ruei-Ling Chen / Ching-Hui Shen

    PLoS ONE, Vol 18, Iss 4, p e

    Pain prevalence analysis.

    2023  Volume 0283520

    Abstract: We developed a pain management system over a 3-year period. In this project, "Towards a pain-free hospital", we combined evidence-based medicine and medical expertise to develop a series of policies. The intervention mainly included the development of ... ...

    Abstract We developed a pain management system over a 3-year period. In this project, "Towards a pain-free hospital", we combined evidence-based medicine and medical expertise to develop a series of policies. The intervention mainly included the development of standard procedures for inpatient pain management, the implementation of hospital-wide pain medicine education and training, the establishment of a dashboard system to track pain status, and regular audits and feedback. This study aimed to gain an understanding of the changes in the prevalence of pain in inpatients under the care of the pain management system. The subjects of the survey are inpatients over 20 years old, and who had been hospitalized in the general ward for at least 3 days. The patients would be excluded if they were unable to respond to the questions. We randomly selected eligible patients in the general ward. Our trained interviewers visited inpatients to complete the questionnaires designed by our pain care specialists. A total of 3,094 inpatients completed the survey from 2018 to 2020. During the three-year period, the prevalence of pain was 69.5% (2018) (reference), 63.3% (2019) (OR:0.768, p<0.01), and 60.1% (2020) (OR:0.662, p <0.001). The prevalence rates of pain in patients undergoing surgery during the 3-year period were 81.4% (2018), 74.3% (2019), and 68.8% (2020), respectively. As for care-related causes of pain, injection, change in position/chest percussion, and rehabilitation showed a decreasing trend over the 3-year period of study. Our pain management system provided immediate professional pain management, and achieved a good result in the management of acute moderate to severe pain, especially perioperative pain. Studies on pain prevalence and Pain-Free Hospitals are scarce in Asia. With the aid of the policies based on evidence-based medicine and the dashboard information system, from 2018 to 2020, the prevalence of pain has decreased year by year.
    Keywords Medicine ; R ; Science ; Q
    Subject code 360
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  8. Article ; Online: Three-year hospital-wide pain management system implementation at a tertiary medical center

    Ming-Chuan Chen / Te-Feng Yeh / Chih-Cheng Wu / Yan-Ru Wang / Chieh-Liang Wu / Ruei-ling Chen / Ching-Hui Shen

    PLoS ONE, Vol 18, Iss

    Pain prevalence analysis

    2023  Volume 4

    Abstract: We developed a pain management system over a 3-year period. In this project, “Towards a pain-free hospital”, we combined evidence-based medicine and medical expertise to develop a series of policies. The intervention mainly included the development of ... ...

    Abstract We developed a pain management system over a 3-year period. In this project, “Towards a pain-free hospital”, we combined evidence-based medicine and medical expertise to develop a series of policies. The intervention mainly included the development of standard procedures for inpatient pain management, the implementation of hospital-wide pain medicine education and training, the establishment of a dashboard system to track pain status, and regular audits and feedback. This study aimed to gain an understanding of the changes in the prevalence of pain in inpatients under the care of the pain management system. The subjects of the survey are inpatients over 20 years old, and who had been hospitalized in the general ward for at least 3 days. The patients would be excluded if they were unable to respond to the questions. We randomly selected eligible patients in the general ward. Our trained interviewers visited inpatients to complete the questionnaires designed by our pain care specialists. A total of 3,094 inpatients completed the survey from 2018 to 2020. During the three-year period, the prevalence of pain was 69.5% (2018) (reference), 63.3% (2019) (OR:0.768, p<0.01), and 60.1% (2020) (OR:0.662, p <0.001). The prevalence rates of pain in patients undergoing surgery during the 3-year period were 81.4% (2018), 74.3% (2019), and 68.8% (2020), respectively. As for care-related causes of pain, injection, change in position/chest percussion, and rehabilitation showed a decreasing trend over the 3-year period of study. Our pain management system provided immediate professional pain management, and achieved a good result in the management of acute moderate to severe pain, especially perioperative pain. Studies on pain prevalence and Pain-Free Hospitals are scarce in Asia. With the aid of the policies based on evidence-based medicine and the dashboard information system, from 2018 to 2020, the prevalence of pain has decreased year by year.
    Keywords Medicine ; R ; Science ; Q
    Subject code 360
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  9. Article: Coptis chinensis

    Hsieh, Pao-Chuan / Chen, Wu-Yuan / Wang, Tzu-Ming / Chu, Yung-Lin

    Journal of traditional and complementary medicine

    2023  Volume 13, Issue 3, Page(s) 270–276

    Abstract: This study aimed to investigate the anti-obesity effects ... ...

    Abstract This study aimed to investigate the anti-obesity effects of
    Language English
    Publishing date 2023-01-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2709698-1
    ISSN 2225-4110
    ISSN 2225-4110
    DOI 10.1016/j.jtcme.2023.01.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Correction to: BMP2 Modified by the m

    Wang, Hai-Feng / Kuang, Ming-Jie / Han, Shi-Jie / Wang, An-Bang / Qiu, Jie / Wang, Feng / Tan, Bing-Yi / Wang, Da-Chuan

    Calcified tissue international

    2024  

    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 304266-2
    ISSN 1432-0827 ; 0944-0747 ; 0008-0594 ; 0171-967X
    ISSN (online) 1432-0827
    ISSN 0944-0747 ; 0008-0594 ; 0171-967X
    DOI 10.1007/s00223-024-01206-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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