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  1. Article ; Online: In Reference to Gastroesophageal Reflux and Chronic Rhinosinusitis: A Mendelian Randomization Study.

    Maniaci, Antonino / Iannella, Giannicola / Chiesa-Estomba, Carlos M / Saibene, Alberto M / Lechien, Jerome R

    The Laryngoscope

    2024  

    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Letter
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.31354
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  2. Article ; Online: Laryngeal verrucous cell carcinoma.

    Lechien, Jerome R / Vaira, Luigi A / Chiesa-Estomba, Carlos M

    Current opinion in otolaryngology & head and neck surgery

    2023  Volume 32, Issue 2, Page(s) 118–124

    Abstract: Purpose of review: To summarize the recent literature on epidemiology, clinical findings, treatment, and survival of laryngeal verrucous cell carcinoma (LVC).: Recent findings: Epidemiological studies report that LVC accounts for 1-3% of all ... ...

    Abstract Purpose of review: To summarize the recent literature on epidemiology, clinical findings, treatment, and survival of laryngeal verrucous cell carcinoma (LVC).
    Recent findings: Epidemiological studies report that LVC accounts for 1-3% of all laryngeal cancers. The incidence is decreasing, while most patients are male individuals and smokers. LVC are commonly detected in early stages because they are more frequently located in the glottic region. Tobacco, alcohol overuse, and, possibly, human papilloma virus are the main contributing factors. Recent studies confirm that surgery is the primary therapeutic approach with better prognosis when compared with other treatment modalities. Surgery alone is associated with 86.8% disease-free and 80.3% overall survival rates, while metastases are anecdotal.
    Summary: LVC presents different clinical, pathological, and survival outcomes when compared with the classic laryngeal squamous cell carcinoma. Biopsies need often to be repeated before getting the most appropriate diagnosis; this supports the need of large-sample biopsy during the tumor diagnosis and staging. The glottic location of most LVC leads to detection of this lesion in its early stages, with ensuing better survival and outcomes after surgery compared with the classic form of squamous cell carcinoma. Future studies are needed to understand the biology of LVC and its related better prognostic outcomes when compared to other laryngeal malignancies.
    MeSH term(s) Humans ; Male ; Female ; Squamous Cell Carcinoma of Head and Neck/pathology ; Carcinoma, Squamous Cell/pathology ; Prognosis ; Larynx ; Laryngeal Neoplasms/diagnosis ; Laryngeal Neoplasms/epidemiology ; Laryngeal Neoplasms/surgery ; Head and Neck Neoplasms/pathology ; Neoplasm Staging
    Language English
    Publishing date 2023-10-10
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1232518-1
    ISSN 1531-6998 ; 1068-9508
    ISSN (online) 1531-6998
    ISSN 1068-9508
    DOI 10.1097/MOO.0000000000000910
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  3. Article ; Online: Dysphagia after supraglottic laryngeal cancer surgery.

    Lechien, Jerome R / Chiesa-Estomba, Carlos M / Maniaci, Antonino / Vaira, Luigi A / Gengler, Isabelle M

    American journal of otolaryngology

    2023  Volume 44, Issue 4, Page(s) 103925

    MeSH term(s) Humans ; Laryngeal Neoplasms/surgery ; Laryngeal Neoplasms/pathology ; Deglutition Disorders/diagnosis ; Deglutition Disorders/etiology ; Deglutition Disorders/surgery ; Squamous Cell Carcinoma of Head and Neck/surgery ; Carcinoma, Squamous Cell/surgery ; Carcinoma, Squamous Cell/pathology ; Head and Neck Neoplasms/surgery ; Laryngectomy/adverse effects ; Retrospective Studies ; Neoplasm Staging
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.103925
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  4. Article ; Online: Performance and Consistency of ChatGPT-4 Versus Otolaryngologists: A Clinical Case Series.

    Lechien, Jérôme R / Naunheim, Mattheuw R / Maniaci, Antonino / Radulesco, Thomas / Saibene, Alberto M / Chiesa-Estomba, Carlos M / Vaira, Luigi A

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2024  

    Abstract: Objective: To study the performance of Chatbot Generative Pretrained Transformer-4 (ChatGPT-4) in the management of cases in otolaryngology-head and neck surgery.: Study design: Prospective case series.: Setting: Multicenter University Hospitals.!# ...

    Abstract Objective: To study the performance of Chatbot Generative Pretrained Transformer-4 (ChatGPT-4) in the management of cases in otolaryngology-head and neck surgery.
    Study design: Prospective case series.
    Setting: Multicenter University Hospitals.
    Methods: History, clinical, physical, and additional examinations of adult outpatients consulting in otolaryngology departments of CHU Saint-Pierre and Dour Medical Center were presented to ChatGPT-4, which was interrogated for differential diagnoses, management, and treatment(s). According to specialty, the ChatGPT-4 responses were assessed by 2 distinct, blinded board-certified otolaryngologists with the Artificial Intelligence Performance Instrument.
    Results: One hundred cases were presented to ChatGPT-4. ChaGPT-4 indicated a mean of 3.34 (95% confidence interval [CI]: 3.09, 3.59) additional examinations per patient versus 2.10 (95% CI: 1.76, 2.34; P = .001) for the practitioners. There was strong consistency (k > 0.600) between otolaryngologists and ChatGPT-4 for the indication of upper aerodigestive tract endoscopy, positron emission tomography and computed tomography, audiometry, tympanometry, and psychophysical evaluations. Primary diagnosis was correctly performed by ChatGPT-4 in 38% to 86% of cases depending on subspecialty. Additional examinations indicated by ChatGPT-4 were pertinent and necessary in 8% to 31% of cases, while the treatment regimen was pertinent in 12% to 44% of cases. The performance of ChatGPT-4 was not influenced by the human-reported level of difficulty of clinical cases.
    Conclusion: ChatGPT-4 may be a promising adjunctive tool in otolaryngology, providing extensive documentation about additional examinations, primary and differential diagnoses, and treatments. The ChatGPT-4 is more effective in providing a primary diagnosis, and less effective in the selection of additional examinations and treatments.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1002/ohn.759
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  5. Article ; Online: ChatGPT performance in laryngology and head and neck surgery: a clinical case-series.

    Lechien, Jerome R / Georgescu, Bianca M / Hans, Stephane / Chiesa-Estomba, Carlos M

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Volume 281, Issue 1, Page(s) 319–333

    Abstract: Objectives: To study the performance of ChatGPT in the management of laryngology and head and neck (LHN) cases.: Methods: History and clinical examination of patients consulting at the Otolaryngology-Head and Neck Surgery department were presented to ...

    Abstract Objectives: To study the performance of ChatGPT in the management of laryngology and head and neck (LHN) cases.
    Methods: History and clinical examination of patients consulting at the Otolaryngology-Head and Neck Surgery department were presented to ChatGPT, which was interrogated for differential diagnosis, management, and treatment. The ChatGPT performance was assessed by two blinded board-certified otolaryngologists using the following items of a composite score and the Ottawa Clinic Assessment Tool: differential diagnosis; additional examination; and treatment options. The complexity of clinical cases was evaluated with the Amsterdam Clinical Challenge Scale test.
    Results: Forty clinical cases were submitted to ChatGPT, accounting for 14 (35%), 12 (30%), and 14 (35%) easy, moderate and difficult cases, respectively. ChatGPT indicated a significant higher number of additional examinations compared to practitioners (p = 0.001). There was a significant agreement between practitioners and ChatGPT for the indication of some common examinations (audiometry, ultrasonography, biopsy, gastrointestinal endoscopy or videofluoroscopy). ChatGPT never indicated some important additional examinations (PET-CT, voice quality assessment, or impedance-pH monitoring). ChatGPT reported highest performance in the proposition of the primary (90%) or the most plausible differential diagnoses (65%), and the therapeutic options (60-68%). The ChatGPT performance in the indication of additional examinations was lowest.
    Conclusions: ChatGPT is a promising adjunctive tool in LHN practice, providing extensive documentation about disease-related additional examinations, differential diagnoses, and treatments. The ChatGPT is more efficient in diagnosis and treatment, rather than in the selection of the most adequate additional examination.
    MeSH term(s) Humans ; Positron Emission Tomography Computed Tomography ; Otolaryngology ; Otolaryngologists ; Biopsy ; Diagnosis, Differential
    Language English
    Publishing date 2023-10-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-023-08282-5
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  6. Article ; Online: Response to: Reconstruction using facial artery system-based flaps. One vascular system for multiple purposes in head and neck reconstructive surgery.

    Gonzalez-Garcia, Jose A / Chiesa-Estomba, Carlos M

    Acta otorrinolaringologica espanola

    2020  Volume 72, Issue 2, Page(s) 136

    MeSH term(s) Arteries/surgery ; Humans ; Reconstructive Surgical Procedures ; Surgical Flaps
    Language Spanish
    Publishing date 2020-12-30
    Publishing country Spain
    Document type Letter ; Comment
    ISSN 2173-5735
    ISSN (online) 2173-5735
    DOI 10.1016/j.otorri.2020.08.007
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  7. Article ; Online: La alteración del olfato y el gusto en pacientes COVID-19. Un recurso diagnóstico en atención primaria.

    Chiesa-Estomba, Carlos M / Lechien, Jerome R / Saussez, Sven

    Atencion primaria

    2020  Volume 52, Issue 8, Page(s) 592–593

    Title translation The alteration of smell and taste in COVID-19 patients. A diagnostic resource in primary care.
    MeSH term(s) COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Humans ; Olfaction Disorders/etiology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Primary Health Care ; Taste Disorders/etiology
    Keywords covid19
    Language Spanish
    Publishing date 2020-05-27
    Publishing country Spain
    Document type Letter
    ZDB-ID 1200787-0
    ISSN 1578-1275 ; 0212-6567
    ISSN (online) 1578-1275
    ISSN 0212-6567
    DOI 10.1016/j.aprim.2020.05.005
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  8. Article ; Online: Is the evolving role of artificial intelligence and chatbots in the field of otolaryngology embracing the future?

    Chiesa-Estomba, Carlos Miguel / Speth, Marlene M / Mayo-Yanez, Miguel / Liu, David T / Maniaci, Antonino / Borsetto, Daniele

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Volume 281, Issue 4, Page(s) 2179–2180

    MeSH term(s) Humans ; Artificial Intelligence
    Language English
    Publishing date 2023-12-22
    Publishing country Germany
    Document type Letter
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-023-08382-2
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  9. Article: Tunnelized Facial Artery Myomucosal Island Flap: A Modification of the FAMM Flap that Enhance its Reconstructive Versatility.

    Vaira, Luigi Angelo / Massarelli, Olindo / Lechien, Jerome R / Chiesa-Estomba, Carlos M / Ayad, Tareck / De Riu, Giacomo

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2023  Volume 76, Issue 1, Page(s) 1419–1420

    Language English
    Publishing date 2023-08-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-023-04169-3
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  10. Article: A Novel Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) 3D Printing Method for Nasal Framework Reconstruction Using Microvascular Free Flaps.

    Chiesa-Estomba, Carlos M / González-García, Jose / Sistiaga-Suarez, Jon A / González Fernández, Iago

    Cureus

    2022  Volume 14, Issue 9, Page(s) e28971

    Abstract: The need for a total or subtotal nose resection represents a dramatic situation for any patient and a challenge for the reconstructive surgeon. Because even in the most skillful hands, an optimal result may be difficult to achieve. In this way, sometimes ...

    Abstract The need for a total or subtotal nose resection represents a dramatic situation for any patient and a challenge for the reconstructive surgeon. Because even in the most skillful hands, an optimal result may be difficult to achieve. In this way, sometimes a free flap reconstruction is needed. A subtotal nasal reconstruction is presented using a fasciocutaneous free flap supported by computer-aided design (CAD), computer-aided manufacturing (CAM), and novel 3D printed guide to recreate the nasal cartilage framework. A successfully free flap reconstruction of the nasal framework was achieved supported by the CAD/CAM 3D printed template. We present a novel approach for nasal total or subtotal reconstruction using a CAD/CAM 3D printed model to create the nasal framework, based on the anatomical and radiological evaluation of the patient.
    Language English
    Publishing date 2022-09-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.28971
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