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  1. Article ; Online: Graphene-Based Optoelectronic Mixer Device for Time-of-Flight Distance Measurements for Enhanced 3D Imaging Applications.

    Kienitz, Paul / Bablich, Andreas / Bornemann, Rainer / Müller, Maurice / Thiel, Felix / Bolívar, Peter Haring

    Nano letters

    2023  Volume 23, Issue 12, Page(s) 5535–5540

    Abstract: A large and growing number of applications benefit from innovative and powerful 3D image sensors. Graphene photodetectors can achieve 3D sensing functionalities by intrinsic optoelectronic frequency mixing due to the nonlinear output characteristics of ... ...

    Abstract A large and growing number of applications benefit from innovative and powerful 3D image sensors. Graphene photodetectors can achieve 3D sensing functionalities by intrinsic optoelectronic frequency mixing due to the nonlinear output characteristics of the sensor. In first proof of principle distance measurement demonstrations, we achieve modulation frequencies of 3.1 MHz, signal-to-noise ratios of ∼40 dB, distance detection up to at least 1 m, and a mean accuracy of 25.6 mm. The scalable More than Moore detector approach enables geometrical fill factors close to 100% and can easily complement powerful functionalities by simple back-end integration on top of CMOS electronics.
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c00909
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Multifrequency Investigation of Single- and Double-Stranded DNA with Scalable Metamaterial-Based THz Biosensors.

    Weisenstein, Christian / Richter, Merle / Wigger, Anna Katharina / Bosserhoff, Anja K / Haring Bolívar, Peter

    Biosensors

    2022  Volume 12, Issue 7

    Abstract: Due to the occurrence of THz-excited vibrational modes in biomacromolecules, the THz frequency range has been identified as particularly suitable for developing and applying new bioanalytical methods. We present a scalable THz metamaterial-based ... ...

    Abstract Due to the occurrence of THz-excited vibrational modes in biomacromolecules, the THz frequency range has been identified as particularly suitable for developing and applying new bioanalytical methods. We present a scalable THz metamaterial-based biosensor being utilized for the multifrequency investigation of single- and double-stranded DNA (ssDNA and dsDNA) samples. It is demonstrated that the metamaterial resonance frequency shift by the DNA's presence depends on frequency. Our experiments with the scalable THz biosensors demonstrate a major change in the degree of the power function for dsDNA by 1.53 ± 0.06 and, in comparison, 0.34 ± 0.11 for ssDNA as a function of metamaterial resonance frequency. Thus, there is a significant advantage for dsDNA detection that can be used for increased sensitivity of biomolecular detection at higher frequencies. This work represents a first step for application-specific biosensors with potential advantages in sensitivity, specificity, and robustness.
    MeSH term(s) Biosensing Techniques ; DNA ; DNA, Single-Stranded
    Chemical Substances DNA, Single-Stranded ; DNA (9007-49-2)
    Language English
    Publishing date 2022-07-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios12070483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: High specificity THz metamaterial-based biosensor for label-free transcription factor detection in melanoma diagnostics.

    Richter, Merle / Loth, Yannik / Wigger, Anna Katharina / Nordhoff, Daniela / Rachinger, Nicole / Weisenstein, Christian / Bosserhoff, Anja Katrin / Bolívar, Peter Haring

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 20708

    Abstract: In this work, we present a promising diagnostic tool for melanoma diagnosis. With the proposed terahertz biosensor, it was possible to selectively and sensitively detect the early growth response protein 2, a transcription factor with an increased ... ...

    Abstract In this work, we present a promising diagnostic tool for melanoma diagnosis. With the proposed terahertz biosensor, it was possible to selectively and sensitively detect the early growth response protein 2, a transcription factor with an increased activity in melanoma cells, from a complex sample of cellular proteins. Fundamentally, the sensor belongs to the frequency selective surface type metamaterials and consists of a two-dimensional array of asymmetrically, doubly split ring resonator unit cells. The single elements are slits in a metallic layer and are complemented by an undercut etch. This allows a selective functionalization of the active area of the sensor and increases the sensitivity towards the target analyte. Hereby, specific detection of a defined transcription factor is feasible.
    MeSH term(s) Humans ; Transcription Factors ; Melanoma/diagnosis ; Gene Expression Regulation ; Psychomotor Agitation
    Chemical Substances Transcription Factors
    Language English
    Publishing date 2023-11-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-46876-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: High-speed nonlinear focus-induced photoresponse in amorphous silicon photodetectors for ultrasensitive 3D imaging applications.

    Bablich, Andreas / Müller, Maurice / Kienitz, Paul / Bornemann, Rainer / Ogolla, Charles Otieno / Butz, Benjamin / Choubey, Bhaskar / Bolívar, Peter Haring

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 10178

    Abstract: A large and growing number of applications benefit from simple, fast and highly sensitive 3D imaging sensors. The Focus-Induced Photoresponse (FIP) can achieve 3D sensing functionalities by simply evaluating the irradiance dependent nonlinear sensor ... ...

    Abstract A large and growing number of applications benefit from simple, fast and highly sensitive 3D imaging sensors. The Focus-Induced Photoresponse (FIP) can achieve 3D sensing functionalities by simply evaluating the irradiance dependent nonlinear sensor response in defect-based materials. Since this advantage is intricately associated to a slow response, the electrical bandwidth of present FIP detectors is limited to a few [Formula: see text] only. The devices presented in this work enable modulation frequencies of 700 kHz and beat frequency detection up to at least 3.8 MHz, surpassing the bandwidth of reported device architectures by more than two orders of magnitude. The sensors achieve a SNR of at least [Formula: see text] at [Formula: see text] and a DC FIP detection limit of 0.6 µW/mm
    MeSH term(s) Imaging, Three-Dimensional ; Silicon
    Chemical Substances Silicon (Z4152N8IUI)
    Language English
    Publishing date 2022-06-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-14330-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Imaging the Terahertz Nanoscale Conductivity of Polycrystalline CsPbBr

    Schäffer, Stephan / Ogolla, Charles Otieno / Loth, Yannik / Haeger, Tobias / Kreusel, Cedric / Runkel, Manuel / Riedl, Thomas / Butz, Benjamin / Wigger, Anna Katharina / Bolívar, Peter Haring

    Nano letters

    2023  Volume 23, Issue 6, Page(s) 2074–2080

    Abstract: Terahertz (THz) radiation is a valuable tool to investigate the electronic properties of lead halide perovskites (LHPs). However, attaining high-resolution information remains elusive, as the diffraction-limited spatial resolution (∼300 μm) of ... ...

    Abstract Terahertz (THz) radiation is a valuable tool to investigate the electronic properties of lead halide perovskites (LHPs). However, attaining high-resolution information remains elusive, as the diffraction-limited spatial resolution (∼300 μm) of conventional THz methods prevents a direct analysis of microscopic effects. Here, we employ THz scattering scanning near-field optical microscopy (THz-sSNOM) for nanoscale imaging of cesium lead bromide (CsPbBr
    Language English
    Publishing date 2023-03-02
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.2c03214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Exploration of Time Reversal for Wireless Communications within Computing Packages

    Bandara, Ama / Rodríguez-Galán, Fátima / de Santana, Elana Pereira / Bolívar, Peter Haring / Alarcón, Eduard / Abadal, Sergi

    2023  

    Abstract: Wireless Network-on-Chip (WNoC) is a promising paradigm to overcome the versatility and scalability issues of conventional on-chip networks for current processor chips. However, the chip environment suffers from delay spread which leads to intense Inter- ... ...

    Abstract Wireless Network-on-Chip (WNoC) is a promising paradigm to overcome the versatility and scalability issues of conventional on-chip networks for current processor chips. However, the chip environment suffers from delay spread which leads to intense Inter-Symbol Interference (ISI). This degrades the signal when transmitting and makes it difficult to achieve the desired Bit Error Rate (BER) in this constraint-driven scenario. Time reversal (TR) is a technique that uses the multipath richness of the channel to overcome the undesired effects of the delay spread. As the flip-chip channel is static and can be characterized beforehand, in this paper we propose to apply TR to the wireless in-package channel. We evaluate the effects of this technique in time and space from an electromagnetic point of view. Furthermore, we study the effectiveness of TR in modulated data communications in terms of BER as a function of transmission rate and power. Our results show not only the spatiotemporal focusing effect of TR in a chip that could lead to multiple spatial channels, but also that transmissions using TR outperform, BER-wise, non-TR transmissions it by an order of magnitude
    Keywords Computer Science - Hardware Architecture ; Electrical Engineering and Systems Science - Signal Processing
    Subject code 003
    Publishing date 2023-07-19
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Conference proceedings ; Online: MIMO Design of 12x64 Element Polarization Sensitive SiGe Array for 3D In-line Detection of Defects at 220-260 GHz

    Kahl, Matthias / Weisenstein, Christian / Hussung, Raphael / Keil, Andreas / Friederich, Fabian / Haring Bolivar, Peter

    2022  

    Abstract: 509 ... 510 ... Non-destructive testing of glass fiber-reinforced composites in mass production requires suitable in-line testing methods that allow single part inspection for quality assurance. We show a design for a MIMO array whose high number of elements ...

    Abstract 509

    510

    Non-destructive testing of glass fiber-reinforced composites in mass production requires suitable in-line testing methods that allow single part inspection for quality assurance. We show a design for a MIMO array whose high number of elements can accelerate the measurement process and enables inline capable 3D imaging systems. The MIMO array achieves a lateral resolution of 1mm and provides for the first time a polarization selective arrangement to better detect defects as deviations in the periodic structures of composite materials. Furthermore, the design of the high frequency PCBs for the installation of the SiGe receivers is shown as a first step on the way to a 3D imaging system.
    Keywords Optical fiber polarization ; Mass production ; Three-dimensional displays ; Quality assurance ; Imaging ; Receivers ; stereo image processing ; DDC::500 Naturwissenschaften und Mathematik
    Language English
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: High-speed nonlinear focus-induced photoresponse in amorphous silicon photodetectors for ultrasensitive 3D imaging applications

    Andreas Bablich / Maurice Müller / Paul Kienitz / Rainer Bornemann / Charles Otieno Ogolla / Benjamin Butz / Bhaskar Choubey / Peter Haring Bolívar

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Volume 11

    Abstract: Abstract A large and growing number of applications benefit from simple, fast and highly sensitive 3D imaging sensors. The Focus-Induced Photoresponse (FIP) can achieve 3D sensing functionalities by simply evaluating the irradiance dependent nonlinear ... ...

    Abstract Abstract A large and growing number of applications benefit from simple, fast and highly sensitive 3D imaging sensors. The Focus-Induced Photoresponse (FIP) can achieve 3D sensing functionalities by simply evaluating the irradiance dependent nonlinear sensor response in defect-based materials. Since this advantage is intricately associated to a slow response, the electrical bandwidth of present FIP detectors is limited to a few $${\text{kHz}}$$ kHz only. The devices presented in this work enable modulation frequencies of 700 kHz and beat frequency detection up to at least 3.8 MHz, surpassing the bandwidth of reported device architectures by more than two orders of magnitude. The sensors achieve a SNR of at least $$\sim 53\;{\text{dB}}$$ ∼ 53 dB at $$115\;{\text{cm}}$$ 115 cm and a DC FIP detection limit of 0.6 µW/mm2. The mature and scalable low-temperature a-Si:H process technology allows operating the device under ambient air conditions waiving additional back-end passivation, geometrical fill factors of $$100\%$$ 100 % and tailoring the FIP towards adjustable 3D sensing applications.
    Keywords Medicine ; R ; Science ; Q
    Subject code 621
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book ; Online: Scalable multi-chip quantum architectures enabled by cryogenic hybrid wireless/quantum-coherent network-in-package

    Alarcón, Eduard / Abadal, Sergi / Sebastiano, Fabio / Babaie, Masoud / Charbon, Edoardo / Bolívar, Peter Haring / Palesi, Maurizio / Blokhina, Elena / Leipold, Dirk / Staszewski, Bogdan / Garcia-Sáez, Artur / Almudever, Carmen G.

    2023  

    Abstract: The grand challenge of scaling up quantum computers requires a full-stack architectural standpoint. In this position paper, we will present the vision of a new generation of scalable quantum computing architectures featuring distributed quantum cores ( ... ...

    Abstract The grand challenge of scaling up quantum computers requires a full-stack architectural standpoint. In this position paper, we will present the vision of a new generation of scalable quantum computing architectures featuring distributed quantum cores (Qcores) interconnected via quantum-coherent qubit state transfer links and orchestrated via an integrated wireless interconnect.

    Comment: 5 pages, 2 figures, accepted for presentation at the IEEE International Symposium on Circuits and Systems (ISCAS) 2023
    Keywords Quantum Physics ; Computer Science - Emerging Technologies
    Publishing date 2023-03-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Ultrasensitive THz biosensor for PCR-free cDNA detection based on frequency selective surfaces.

    Weisenstein, Christian / Schaar, Dominik / Katharina Wigger, Anna / Schäfer-Eberwein, Heiko / Bosserhoff, Anja K / Haring Bolívar, Peter

    Biomedical optics express

    2019  Volume 11, Issue 1, Page(s) 448–460

    Abstract: THz technologies are a powerful tool for label-free detection of biomolecules. However, significant reduction of the lower detection limit is required to apply THz-sensors in biomedical diagnosis. This paper reports an ultrasensitive THz-biosensor based ... ...

    Abstract THz technologies are a powerful tool for label-free detection of biomolecules. However, significant reduction of the lower detection limit is required to apply THz-sensors in biomedical diagnosis. This paper reports an ultrasensitive THz-biosensor based on asymmetric double split ring resonators (aDSRR) for the direct label- and PCR-free detection of DNA at physiologically relevant concentrations. We introduce selective functionalization and localized electric field concentration to enhance aDSRR sensitivity and specificity. The sensor characteristics are demonstrated using the human tumor marker MIA in cDNA samples produced from total RNA without PCR-amplification. Measurements of DNA samples with concentrations as low as 1.55 × 10
    Language English
    Publishing date 2019-12-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2572216-5
    ISSN 2156-7085
    ISSN 2156-7085
    DOI 10.1364/BOE.380818
    Database MEDical Literature Analysis and Retrieval System OnLINE

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