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Article: Study of changes in rs2283265 polymorphisms in dopamine receptor D2 and rs27072 in dopamine transporter gene (SLC6A3) in patients with attention-deficit hyperactivity disorder.

Safavi, Parvin / Soleimani Farsani, Hossein / Farrokhi, Effat / Malekpour Tehrani, Afsaneh / Khoshdel, Nika / Khoshdel, Abolfazl

Iranian journal of child neurology

2022 Volume 16, Issue 3, Page(s) 121–132

Abstract: Objectives: Attention-deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children that lead to numerous complications. This study examined the changes in rs2283265 polymorphisms in the dopamine receptor D2 (DRD2) ... ...

Abstract	Objectives: Attention-deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children that lead to numerous complications. This study examined the changes in rs2283265 polymorphisms in the dopamine receptor D2 (DRD2) and rs27072 in the dopamine transporter gene (SLC6A3) in ADHD patients. Materials & methods: This descriptive-analytical study was performed on children aged 4-12 years with ADHD. In this study, 100 patients in the ADHD group (according to DSM-IV-TR criteria and diagnosed by interview by a child and adolescent psychiatrist) and 100 children in the control group (including patients referring to the pediatrician without hyperactivity) were enrolled. Two polymorphisms rs2283265 and rs27072 in two groups were comparatively investigated using PCR-RFLP method and restriction enzymes. Data were analyzed using SPSS 17. Results: There was a significant correlation between gender and ADHD, and the disease was more common in boys (P=0.021). In this study, there was no significant relationship between ADHD types and frequency distribution of rs2283265 (DRD2) and rs27072 (SLC6A3) polymorphism genotypes (P<0.05). However, there was a significant correlation between distribution of rs2283265 (DRD2) and rs27072 (SLC6A3) polymorphisms and ADHD (P<0.05). Conclusion: It seems that the changes in DRD2 and SLC6A3 genes are associated with ADHD, and study of these genes can be helpful in diagnosis and genetic screening.
Language	English
Publishing date	2022-07-16
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2542305-8
ISSN	2008-0700 ; 1735-4668
ISSN (online)	2008-0700
ISSN	1735-4668
DOI	10.22037/ijcn.v15i4.25340
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Study of the association between serum zinc concentration in pregnant women and preterm birth

Sheida Shabanian / Abolfazl Khoshdel / Majid Dezfuli / Fatemeh Famouri

Journal of Shahrekord University of Medical Sciences, Vol 23, Iss 3, Pp 102-

2021 Volume 105

Abstract: Background and aims: Preterm birth can cause high morbidity and mortality in women. Previous evidence has confirmed the association between zinc (Zn) deficiency in x women and some pregnancy complications. This study investigated the association between ... ...

Abstract	Background and aims: Preterm birth can cause high morbidity and mortality in women. Previous evidence has confirmed the association between zinc (Zn) deficiency in x women and some pregnancy complications. This study investigated the association between serum Zn concentration in pregnant women and preterm birth. Methods: This case-control study focused on evaluating 76 pregnant women with preterm birth (case group) and 62 pregnant women with term birth (control group) and was conducted in the obstetrics ward of Hajar hospital, Shahrekord, Iran in 2014. The Zn level was measured by spectrophotometry and data were analyzed by SPSS, version 15. Results: The prevalence of Zn deficiency was 95.6%. The mean of serum Zn concentration was 39.62±11.83 and 59.81±8.8 in the preterm and term delivery groups, respectively (P<0.001). Similarly, the mean of serum Zn concentrations was 43.06±15.6 and 50.46±13.8 in women with and without the rupture of pregnancy membranes, respectively (P=0.01). Based on the findings, the serum Zn concentration was not significantly associated with parity (P=0.634). Conclusion: Although a decrease in the serum Zn concentration could lead to premature rupture of membranes during pregnancy and preterm birth, it could not be considered as the main factor for preterm birth. In addition, Zn deficiency was highly prevalent in pregnant women. Therefore, nutritional interventions should be performed to prevent complications due to the deficiency of micronutrients such as Zn so that to increase health maintenance in mothers and children.
Keywords	serum ; zinc ; pregnant women ; preterm birth ; Medicine ; R
Subject code	610
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	Shahrekord University of Medical Sciences
Document type	Article ; Online
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Article ; Online: Changes in Hemoglobin Level and Mean Corpuscular Volume During the Convalescent Phase of Acute Febrile Illness in Children

Kiavash Fekri / Fatemeh Kianpour / Soleiman Kheiri / Nika Khoshdel / Abolfazl Khoshdel

Acta Medica Iranica, Vol 58, Iss

A Study of the Possible Role of Hemolysis

2020 Volume 1

Abstract: Fever is one of the most common clinical manifestations in children. During the early days of acute febrile illness, some decrease in hemoglobin levels occurs due to unspecified cause. 64 children aged 6 months to 12-year-old with a fever higher than 38° ...

Abstract	Fever is one of the most common clinical manifestations in children. During the early days of acute febrile illness, some decrease in hemoglobin levels occurs due to unspecified cause. 64 children aged 6 months to 12-year-old with a fever higher than 38° for more than one day and with a diagnosis of acute febrile illness were admitted. The values of MCV, ESR, CRP, and hepcidin were measured at baseline and then 7 to 10 days after the improvement of the fever. The levels of reticulocytes, LDH, and bilirubin were also measured in two stages. Data analysis was done using SPSS software. The mean hemoglobin level in the acute phase of febrile illness was significantly increased 7-10 days after discontinuation of the fever by 12.87±1.09 g/dl (P<0.001). The MCV level also significantly increased (P<0.001), and levels of CRP, ESR, LDH, bilirubin, and hepcidin showed significantly decreased during the convalescent phase compared to acute febrile phase, but the level of erythrocyte increased. The present study confirmed the decrease in hemoglobin in children with acute febrile illness. Increasing of bilirubin, LDH, hepcidin, level, and no bleeding was observed during acute febrile infection in children.
Keywords	Hemoglobin ; Mean corpuscular volume (MCV) ; Acute febrile illness ; Medicine (General) ; R5-920
Subject code	630
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	Tehran University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: A comprehensive survey of research towards AI-enabled unmanned aerial systems in pre-, active-, and post-wildfire management

Boroujeni, Sayed Pedram Haeri / Razi, Abolfazl / Khoshdel, Sahand / Afghah, Fatemeh / Coen, Janice L. / ONeill, Leo / Fule, Peter Z. / Watts, Adam / Kokolakis, Nick-Marios T. / Vamvoudakis, Kyriakos G.

2024

Abstract: Wildfires have emerged as one of the most destructive natural disasters worldwide, causing catastrophic losses in both human lives and forest wildlife. Recently, the use of Artificial Intelligence (AI) in wildfires, propelled by the integration of ... ...

Abstract	Wildfires have emerged as one of the most destructive natural disasters worldwide, causing catastrophic losses in both human lives and forest wildlife. Recently, the use of Artificial Intelligence (AI) in wildfires, propelled by the integration of Unmanned Aerial Vehicles (UAVs) and deep learning models, has created an unprecedented momentum to implement and develop more effective wildfire management. Although some of the existing survey papers have explored various learning-based approaches, a comprehensive review emphasizing the application of AI-enabled UAV systems and their subsequent impact on multi-stage wildfire management is notably lacking. This survey aims to bridge these gaps by offering a systematic review of the recent state-of-the-art technologies, highlighting the advancements of UAV systems and AI models from pre-fire, through the active-fire stage, to post-fire management. To this aim, we provide an extensive analysis of the existing remote sensing systems with a particular focus on the UAV advancements, device specifications, and sensor technologies relevant to wildfire management. We also examine the pre-fire and post-fire management approaches, including fuel monitoring, prevention strategies, as well as evacuation planning, damage assessment, and operation strategies. Additionally, we review and summarize a wide range of computer vision techniques in active-fire management, with an emphasis on Machine Learning (ML), Reinforcement Learning (RL), and Deep Learning (DL) algorithms for wildfire classification, segmentation, detection, and monitoring tasks. Ultimately, we underscore the substantial advancement in wildfire modeling through the integration of cutting-edge AI techniques and UAV-based data, providing novel insights and enhanced predictive capabilities to understand dynamic wildfire behavior.
Keywords	Computer Science - Machine Learning ; Computer Science - Artificial Intelligence
Subject code	690
Publishing date	2024-01-04
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Phytotherapy with

Panahandeh, Gholamreza / Khoshdel, Abolfazl / Sedehi, Morteza / Aliakbari, Azam

Journal of clinical and diagnostic research : JCDR

2017 Volume 11, Issue 3, Page(s) SC16–SC19

Abstract: Introduction: Jaundice is one of the most common causes of admission to hospital in newborns which is often associated with several complications.: Aim: The present study was conducted to evaluate the effect of : Materials and methods: In this ... ...

Abstract	Introduction: Jaundice is one of the most common causes of admission to hospital in newborns which is often associated with several complications. Aim: The present study was conducted to evaluate the effect of Materials and methods: In this double-blind, randomized controlled trials 70 term infants hospitalized due to jaundice in 2014 were enrolled. Control group was treated with full-time phototherapy alone using LED except when the infants were breastfed and case group with phototherapy, as per the protocol in the control group, along with and topical Results: There was a significant difference in mean indirect bilirubin level between the two groups p<0.05, such that the mean indirect bilirubin level was higher in the control group. Furthermore, no significant difference was seen in direct bilirubin level between the two groups at discharge p>0.05. Conclusion: H. vulgare
Language	English
Publishing date	2017-03-01
Publishing country	India
Document type	Journal Article
ZDB-ID	2775283-5
ISSN	0973-709X ; 2249-782X
ISSN (online)	0973-709X
ISSN	2249-782X
DOI	10.7860/JCDR/2017/22177.9586
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The effect of adding ferrous sulfate to methylphenidate on attention-deficit/hyperactivity disorder in children.

Panahandeh, Gholamreza / Vatani, Bahareh / Safavi, Parvin / Khoshdel, Abolfazl

Journal of advanced pharmaceutical technology & research

2017 Volume 8, Issue 4, Page(s) 138–142

Abstract: Attention deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children with several complications. This study was conducted to investigate the effect of adding ferrous sulfate to methylphenidate in decreasing ADHD ... ...

Abstract	Attention deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children with several complications. This study was conducted to investigate the effect of adding ferrous sulfate to methylphenidate in decreasing ADHD symptoms. This study was a double-blind, randomized clinical trial. In this study, 42 nonanemic children with ADHD and serum ferritin below 30 mg/ml were enrolled according to convenience sampling and randomly assigned to two groups of 21 each, cases and controls. The two groups were matched for age and sex. The case group was administered with ferrous sulfate 5 mg/kg in addition to methylphenidate up to 1 mg/kg and the control group with methylphenidate alone. The scores on child symptoms inventory-4 (CSI-4) were recorded at baseline and after 2 months of treatment. Data were analyzed by
Language	English
Publishing date	2017-10-31
Publishing country	India
Document type	Journal Article
ISSN	2231-4040
ISSN	2231-4040
DOI	10.4103/japtr.JAPTR_45_17
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Article ; Online: Study of respiratory allergens and associated factors in patients with allergic rhinitis referring to Imam Ali clinic in Shahrekord

Mohammad Ali Zamani / Monireh Alipour / Ali Ahmadi / Abolfazl Khoshdel

Journal of Shahrekord University of Medical Sciences, Vol 21, Iss 3, Pp 131-

2019 Volume 136

Abstract: Background and aims: Respiratory allergens cause several problems for people with allergic rhinitis and are considered as a global challenge. This disease is an IgE-mediated nasal inflammatory disease that is triggered by the contact of the allergen. ... ...

Abstract	Background and aims: Respiratory allergens cause several problems for people with allergic rhinitis and are considered as a global challenge. This disease is an IgE-mediated nasal inflammatory disease that is triggered by the contact of the allergen. Therefore, this study was conducted to investigate respiratory allergens and associated factors in patients with allergic rhinitis who referred to a clinic in Shahrekord located in the southwest of Iran. Methods: In this cross-sectional study, 200 patients including 100 males and 100 females were enrolled using a convenience sampling technique. Diagnoses were made according to clinical symptoms and observation. In addition, the skin prick tests were used to detect the allergens. Finally, data were recorded and then analyzed by Stata. Results: Based on the results, 73.5%, 70.5%, 46%, and 43% of the patients were allergic to the following allergens including Dermatophagoid pteronyssinus, Dermatophagoides parinae, tree, and grass, respectively. Further, the mean height in the group with a positive and negative test for the inhaled allergens equaled 144.92±29.72 and 131.65±30.93, respectively, with a statistically significant difference (P<0.05). However, the mean weight, age, and the time at the onset of the disease were not significantly different between the two groups (P>0.05). Furthermore, the negative or positive reaction to the allergens failed to significantly differ with respect to gender, marital status, occupation, the county of residence, the area of residence, family size, and a family history of the disease (P>0.05). Conclusion: Allergic rhinitis is regarded as a common disorder among teenagers and young adults in this setting. Allergy to one or more respiratory allergens was found to be highly prevalent in patients with allergic rhinitis and the highest rate of allergy was observed to the mites, followed by tree and grass.
Keywords	Allergens ; Allergic rhinitis ; Respiratory system ; Medicine ; R
Subject code	610
Language	Persian
Publishing date	2019-07-01T00:00:00Z
Publisher	Shahrekord University of Medical Sciences
Document type	Article ; Online
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Article: Effect of Ramadan Fast on Liver Function Tests.

Nasiri, Jafar / Kheiri, Soleiman / Khoshdel, Abolfazl / Boroujeni, Amirgholi Jafari

Iranian journal of medical sciences

2016 Volume 41, Issue 5, Page(s) 459–460

Language	English
Publishing date	2016-08-31
Publishing country	Iran
Document type	Journal Article
ZDB-ID	603872-4
ISSN	1735-3688 ; 0253-0716
ISSN (online)	1735-3688
ISSN	0253-0716
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Article: Comparison of amoxicillin and metronidazole effect on three-drug regimen for the treatment of

Kasiri, Karam-Ali / Khoshdel, Abolfazl / Karimi, Afshin / Sedehi, Morteza / Kasiri, Niloufar

Journal of advanced pharmaceutical technology & research

2017 Volume 8, Issue 2, Page(s) 63–66

Abstract: Helicobacter ... ...

Abstract	Helicobacter pylori
Language	English
Publishing date	2017-03-28
Publishing country	India
Document type	Journal Article
ISSN	2231-4040
ISSN	2231-4040
DOI	10.4103/japtr.JAPTR_162_16
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Article ; Online: Phytotherapy with Hordeum Vulgare

Gholamreza Panahandeh / Abolfazl Khoshdel / Morteza Sedehi / Azam Aliakbari

Journal of Clinical and Diagnostic Research, Vol 11, Iss 3, Pp SC16-SC

A Randomized Controlled Trial on Infants with Jaundice

2017 Volume 19

Abstract: Introduction: Jaundice is one of the most common causes of admission to hospital in newborns which is often associated with several complications. Aim: The present study was conducted to evaluate the effect of H. vulgare in reducing jaundice. Materials ... ...

Abstract	Introduction: Jaundice is one of the most common causes of admission to hospital in newborns which is often associated with several complications. Aim: The present study was conducted to evaluate the effect of H. vulgare in reducing jaundice. Materials and Methods: In this double-blind, randomized controlled trials 70 term infants hospitalized due to jaundice in 2014 were enrolled. Control group was treated with full-time phototherapy alone using LED except when the infants were breastfed and case group with phototherapy, as per the protocol in the control group, along with and topical H. vulgare seed flour three times a day. Data were analysed using and analysis of covariance (ANCOVA) and paired t-test in SPSS version 16.0. Results: There was a significant difference in mean indirect bilirubin level between the two groups p<0.05, such that the mean indirect bilirubin level was higher in the control group. Furthermore, no significant difference was seen in direct bilirubin level between the two groups at discharge p>0.05. Conclusion: H. vulgare flour can cause decrease in indirect bilirubin. Because the rate of decrease in indirect bilirubin can be effective in preventing severe complications due to bilirubinemia, H. vulgare can be used as a complementary therapy to treat jaundice.
Keywords	hordeum vulgare flour ; neonatal jaundice ; phototherapy ; Medicine ; R
Language	English
Publishing date	2017-03-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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