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  1. Article: Child, Robert

    Humphrey, Carol Sue

    American national biography Vol.4

    1999  Volume 4

    Author's details Carol Sue Humphrey
    MeSH term(s) Physicians ; History of Medicine ; History, 17th Century
    Keywords United Kingdom ; United States
    Language English
    Size p. 809-810.
    Publisher Oxford University Press
    Publishing place New York
    Document type Article
    ISBN 0195206355 ; 9780195206357
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Article: Exploring the Diagnostic Spectrum of Children with Raised Faecal Calprotectin Levels.

    Vernon-Roberts, Angharad / Humphrey, Olivia / Day, Andrew S

    Children (Basel, Switzerland)

    2024  Volume 11, Issue 4

    Abstract: Faecal calprotectin (FC) is a marker of gut inflammation. The cause and relevance of raised FC in children outside the context of established inflammatory bowel disease (IBD) have had minimal attention. This study aimed to address this by carrying out a ... ...

    Abstract Faecal calprotectin (FC) is a marker of gut inflammation. The cause and relevance of raised FC in children outside the context of established inflammatory bowel disease (IBD) have had minimal attention. This study aimed to address this by carrying out a retrospective study on children with abnormal FC tests aged 4-17 years without established IBD in the South Island, New Zealand. Abnormal FC results were stratified: 51-249 μg/g, 250-499 μg/g, and 500+ μg/g, and participants were categorised into diagnostic groups. Data were collected on symptoms and diagnostic tests. Three-hundred and ten children had abnormal index FC results, with a mean age of 12.9 years, and a 55% proportion of females. The median FC was 125 μg/g; 71% had levels 51-249 μg/g and 21% had levels 500+ μg/g. Of those with FC 500+ μg/g, 89% either had infectious diarrhoea or were diagnosed with IBD at the time of, or subsequent to, the index FC. Alarm symptoms did not delineate between groups with FC 500+ μg/g. Abnormalities in platelet levels, abdominal ultrasound, and colonoscopy were more frequent for children diagnosed with IBD. Repeat FC test levels were significantly reduced except for those subsequently diagnosed with IBD. Abnormal FC levels for the majority were below the level indicative of mucosal inflammation. Repeat FC testing could play an important role in distinguishing between diagnoses.
    Language English
    Publishing date 2024-04-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children11040420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: What does cognitive screening reveal about early cognitive performance following endovascular clot retrieval and intravenous thrombolysis in acute ischaemic stroke?

    Humphrey, Sam / Pike, Kerryn E / Long, Brian / Ma, Henry / Bourke, Robert / Byrne, Danielle / Wright, Bradley / Wong, Dana

    Brain impairment : a multidisciplinary journal of the Australian Society for the Study of Brain Impairment

    2024  Volume 25

    Abstract: Background Little is known regarding cognitive outcomes following treatment with endovascular clot retrieval (ECR) and intravenous tissue plasminogen activator (t-PA). We aimed to determine if there were any differences on a measure of cognitive ... ...

    Abstract Background Little is known regarding cognitive outcomes following treatment with endovascular clot retrieval (ECR) and intravenous tissue plasminogen activator (t-PA). We aimed to determine if there were any differences on a measure of cognitive screening between patients treated with ECR, t-PA, and those who were managed conservatively. Methods The medical records of ischaemic stroke patients admitted to Monash Medical Centre between January 2019 and December 2019 were retrospectively reviewed. Information extracted from medical records included age, sex, National Institutes of Health Stroke Scale at presentation, location of occlusion, treatment type, medical history, and cognitive screening performance measured by the Montreal Cognitive Assessment (MoCA). Results Eighty-two patients met the inclusion criteria (mean age = 66.5 ± 13.9; 49 male, 33 female). Patients treated with ECR performed significantly better on the MoCA (n  = 36, 24.1 ± 4.3) compared to those who were managed conservatively (n  = 26, 20.7 ± 5.5). Performance for patients treated with t-PA (n  = 20, 23.9 ± 3.5) fell between the ECR and conservative management groups, but they did not significantly differ from either. Conclusion Our retrospective chart review found that ischaemic stroke patients treated with ECR appear to perform better on cognitive screening compared to patients who are managed conservatively. We also found that patients treated with ECR and t-PA appear to have similar cognitive screening performances in the acute stages following ischaemic stroke, although this finding is likely to have been impacted by group differences in stroke characteristics and may reflect the possibility that the ECR group performed better than expected based on their stroke severity.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Aged ; Aged, 80 and over ; Tissue Plasminogen Activator/therapeutic use ; Stroke/drug therapy ; Brain Ischemia/drug therapy ; Fibrinolytic Agents/therapeutic use ; Retrospective Studies ; Ischemic Stroke/drug therapy ; Thrombosis/drug therapy ; Thrombolytic Therapy/methods ; Cognition
    Chemical Substances Tissue Plasminogen Activator (EC 3.4.21.68) ; Fibrinolytic Agents
    Language English
    Publishing date 2024-04-02
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2180113-7
    ISSN 1839-5252 ; 1443-9646
    ISSN (online) 1839-5252
    ISSN 1443-9646
    DOI 10.1071/IB23066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Coproducing the Learning Environment: Lessons Learned from a Year of Near-Peer Teaching.

    Humphrey, Kristen N / Daulton, Robert S / Weber, Danielle / Sall, Dana / Kelleher, Matthew

    Journal of medical education and curricular development

    2022  Volume 9, Page(s) 23821205221096288

    Abstract: Purpose: Few medical schools offer electives with the goal of teaching medical students to be effective teachers prior to residency. We developed a novel year-long, longitudinal course, the Clinical Teaching Elective (CTE), that develops fourth-year ... ...

    Abstract Purpose: Few medical schools offer electives with the goal of teaching medical students to be effective teachers prior to residency. We developed a novel year-long, longitudinal course, the Clinical Teaching Elective (CTE), that develops fourth-year medical students as student teachers within Clinical Skills (CS).
    Approach/methods: The elective was designed by Clinical Skills (CS) Course Directors and two fourth-year medical students (M4) as a longitudinal elective. The elective involves teaching in the Simulation Center where M4 student instructors teach first and second-year medical students. Each session, in addition to simulated patient case topics, emphasizes application of a key topic within medical education (ie clinical reasoning, reflective practice, dual process reasoning).
    Discussion: Six "teaching takeaways" were crafted to summarize common themes experienced by near-peer medical student educators. Teaching is not about the destination, but rather the diagnostic journey.Students thrive when learning is co-produced.A little bit of praise goes a long way.You can't please every learner.When students struggle, there is more to teach than just the answer.Facilitating learner independent thinking promotes future autonomy.
    Significance: A novel CTE for fourth-year medical students that emphasizes medical education pedagogy prepares students to serve as educators in residency. The CTE provides an opportunity for medical students to develop into effective clinical educators prior to residency. The focus of our elective on medical education pedagogy furthers medical student understanding of adult learning theory and fosters professional development in teaching clinical reasoning.
    Language English
    Publishing date 2022-05-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2798123-X
    ISSN 2382-1205
    ISSN 2382-1205
    DOI 10.1177/23821205221096288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Increased Regular Season Soft Tissue Injury Rates in National Football League (NFL) Players May Be Associated With the Canceled 2020 NFL Preseason Due to COVID-19.

    Sclafani, Salvatore / Frane, Nicholas / Humphrey, Tyler J / Miceli, Joseph / Trasolini, Robert

    Cureus

    2022  Volume 14, Issue 5, Page(s) e24674

    Abstract: Introduction The purpose of this study is to evaluate the rates of regular season soft tissue injuries in National Football League (NFL) players during the 2020 season, which had a canceled preseason due to the COVID-19 pandemic. Methods This study ... ...

    Abstract Introduction The purpose of this study is to evaluate the rates of regular season soft tissue injuries in National Football League (NFL) players during the 2020 season, which had a canceled preseason due to the COVID-19 pandemic. Methods This study retrospectively reviewed the injury rates of the 2020-2021 NFL regular season in comparison to the 2018-2019 NFL regular season using publicly available injury data. The focus of our analysis was comparing the following soft tissue injuries: hamstring, groin, calf, quadriceps, thigh, knee - anterior cruciate ligament (ACL), pectoral, and Achilles. The week of injury occurrence, duration of injury in weeks, position of the injured player, and age of the NFL player at injury were obtained. Injury rates were calculated per 1000 athletic exposures with 95% confidence intervals (CIs). A chi-square test and Student's t-test were utilized as appropriate. Results There were 1370 total injuries in the 2018-2019 regular NFL season and 2086 total injuries reported in the 2020-2021 regular NFL season. The total number of injuries per 1000 athletic exposures was significantly higher in the 2020-2021 NFL season compared to the 2018-2019 NFL season (88.57 versus 58.17, p < 0.001). The rates of injuries per 1000 athletic exposures for hamstring (9.98 versus 5.31, p = 0.043), groin (5.56 versus 2.46, p = 0.007), calf (4.08 versus 1.61, p = 0.006), quadriceps (2.00 versus 0.72, p = 0.030), and thigh (1.23 versus 0.30, p = 0.012) injuries were significantly higher in the 2020-2021 regular NFL season compared to the 2018-2019 NFL regular season. Conclusions The 2020-2021 NFL season had a significantly higher incidence of soft tissue injuries compared to the 2018-2019 regular NFL season, which may have been associated with the absent preseason due to the COVID-19 pandemic and an abrupt increase in the athletic workload of players.
    Language English
    Publishing date 2022-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.24674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Interventions to improve access to primary care for inclusion health groups in England: a scoping review.

    Carruthers, Elspeth / Dobbin, Joanna / Fagan, Lucy / Humphrey, Ada / Nagasivam, Ahimza / Stevenson, Kerrie / Yuan, Jin-Min / Aldridge, Robert W / Burns, Rachel

    Lancet (London, England)

    2023  Volume 402 Suppl 1, Page(s) S32

    Abstract: Background: Everyone in England has the right to primary care without financial charges. Nevertheless, evidence shows that barriers remain for inclusion health populations such as vulnerable migrants, people experiencing homelessness, Gypsy, Roma, and ... ...

    Abstract Background: Everyone in England has the right to primary care without financial charges. Nevertheless, evidence shows that barriers remain for inclusion health populations such as vulnerable migrants, people experiencing homelessness, Gypsy, Roma, and Traveller (GRT) communities, and people who sell sex. There is little evidence for what works to improve access. This study was a scoping review of interventions to improve access to mainstream primary care for inclusion health groups in England.
    Methods: In this scoping review, we searched databases (Embase, Medline, APA PsychInfo, the Cochrane Collaboration Library, Web of Science and CINAHL) and grey literature sources, including the National Health Service and National Institute for Clinical Excellence, for articles published in English between Jan 1, 2010, and Dec 31, 2020, with no limit on study design. Data were extracted according to inclusion criteria, including interventions taking place in England and targeting people with insecure immigration status, people who sell sex, people experiencing homelessness, and GRT communities. Results were presented in a narrative synthesis.
    Findings: 39 studies describing one or more interventions were included: four peer-reviewed articles (one randomised trial, two quality improvement projects, and one mixed-methods study protocol) and 25 grey literature items (38 interventions in total). Interventions mostly targeted people with insecure immigration status (17/38, 45%), and a majority (12/38, 32%) took place in London. The most common types of intervention were training, education, and resources (such as leaflets or websites) for patients or staff (25/38, 66%), and most interventions targeted GP registration processes (28/38, 74%). Interventions commonly involved voluntary and community sector organisations (16/38, 42%). Most interventions were not evaluated to understand their effectiveness (23/38, 61%). Sources with evaluations identified staff training, direct patient advocacy, and involvement of people with lived experience as effective elements.
    Interpretation: Interventions to improve access to primary care for inclusion health groups in England were heterogeneous, commonly undertaken at community level, and developed to serve local inclusion health groups. Considerations for policymakers and practitioners include groups and geographical areas less commonly included in interventions, the elements of positive practice identified in evaluations, and the need for evaluation of future interventions.
    Funding: National Institute for Health and Care Research (NIHR 202050).
    MeSH term(s) Humans ; State Medicine ; Access to Primary Care ; England ; Roma ; London
    Language English
    Publishing date 2023-11-23
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)02081-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: PeRsOnaliSed care Planning for oldER people with frailty (PROSPER): protocol for a randomised controlled trial.

    Heaven, Anne / Bower, Peter / Day, Florence / Farrin, Amanda / Fernadez, Catherine / Foster, Marilyn / Foy, Robbie / Hawkins, Rebecca / Hulme, Claire / Humphrey, Sara / Lawton, Rebecca / Parker, Catriona / Thompson, Ellen / West, Robert / Clegg, Andrew

    Trials

    2024  Volume 25, Issue 1, Page(s) 8

    Abstract: Background: Frailty is common in older age and is characterised by loss of biological reserves across multiple organ systems. These changes associated with frailty mean older people can be vulnerable to sudden, dramatic changes in health because of ... ...

    Abstract Background: Frailty is common in older age and is characterised by loss of biological reserves across multiple organ systems. These changes associated with frailty mean older people can be vulnerable to sudden, dramatic changes in health because of relatively small problems. Older people with frailty are at increased risk of adverse outcomes including disability, hospitalisation, and care home admission, with associated reduction in quality of life and increased NHS and social care costs. Personalised Care Planning offers an anticipatory, preventative approach to supporting older adults to live independently for longer, but it has not been robustly evaluated in a population of older adults with frailty.
    Methods: Following an initial feasibility study, this multi-centre, individually randomised controlled trial aims to establish whether personalised care planning for older people improves health-related quality of life. It will recruit 1337 participants from general practices across Yorkshire and Humber and Mid-Mersey in the North of England. Eligible patients will be aged 65 and over with an electronic frailty index score of 0.21 or above, living in their own homes, without severe cognitive impairment and not in receipt of end-of-life care. Following confirmation of eligibility, informed consent and baseline data collection, participants will be individually randomised to the PeRsOnaliSed care Planning for oldER people with frailty (PROSPER) intervention or usual care in a 2.6:1 allocation ratio. Participants will not be blinded to allocation, but data collection and analysis will be blinded. The intervention will be delivered over 12 weeks by a Personal Independence Co-ordinator worker based within a voluntary sector organisation, Age UK. The primary outcomes are health-related quality of life, measured using both the physical and mental components of the Short-Form 12 Item Health Questionnaire at 12 months after randomisation. Secondary outcomes comprise activities of daily living, self-management capabilities and loneliness, admission to care homes, hospitalisations, and health and social care resource use at 12 months post randomisation. Parallel cost-effectiveness and process evaluations will be conducted alongside the trial.
    Discussion: The PROSPER study will evaluate the effectiveness and cost-effectiveness of a personalised care planning approach for older people with frailty and inform the process of its implementation.
    Trial registration: ISRCTN16123291 .  Registered on  28 August 2020.
    MeSH term(s) Humans ; Aged ; Activities of Daily Living ; Frailty/diagnosis ; Frailty/therapy ; Quality of Life ; England ; Surveys and Questionnaires ; Cost-Benefit Analysis ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-023-07857-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: C reactive protein response after routine vaccination among rural Zimbabwean infants.

    Broad, Jonathan / Church, James / Mutasa, Kuda / Majo, Florence D / Tavengwa, Naume V / Chasekwa, Bernard / Humphrey, Jean H / Ntozini, Robert / Prendergast, Andrew J

    Archives of disease in childhood

    2022  Volume 108, Issue 2, Page(s) 146–147

    MeSH term(s) Infant ; Humans ; C-Reactive Protein ; Zimbabwe/epidemiology ; Vaccination ; Immunization Schedule ; Rural Population
    Chemical Substances C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2022-11-28
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2022-324883
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Once upon a Time in War

    Humphrey, Robert E

    The 99th Division in World War II

    (Campaigns and Commanders Series ; v.18)

    2014  

    Series title Campaigns and Commanders Series ; v.18
    Language English
    Size Online-Ressource (387 p)
    Publisher University of Oklahoma Press
    Publishing place Norman
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9780806139463 ; 0806139463
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  10. Article ; Online: Response to Letter to the Editor Regarding "Does the Primary Surgical Approach Matter When Choosing the Approach for Revision Total Hip Arthroplasty?"

    Christensen, Thomas H / Humphrey, Tyler J / Salimy, Mehdi S / Roundy, Robert S / Goel, Rahul K / Guild, George N / Schwarzkopf, Ran / Bedair, Hany S / Aggarwal, Vinay K

    The Journal of arthroplasty

    2023  Volume 39, Issue 2, Page(s) e7–e9

    MeSH term(s) Humans ; Arthroplasty, Replacement, Hip ; Reoperation
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Letter
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2023.09.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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