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  1. Article: Laparoscopy in the coronavirus disease 2019 (COVID-19) era.

    Angioni, Stefano

    Gynecological surgery

    2020  Volume 17, Issue 1, Page(s) 3

    Abstract: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged in China at the end of 2019 has become a pandemic infection that has now involved 200 countries with 465,915 confirmed cases and 21,031 confirmed deaths. Unfortunately, ... ...

    Abstract The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged in China at the end of 2019 has become a pandemic infection that has now involved 200 countries with 465,915 confirmed cases and 21,031 confirmed deaths. Unfortunately, many data have shown that the high number of undocumented infections could have a major role in the rapid diffusion of the disease. In most of the nations involved, non-urgent, non-cancer procedures have been stopped to reallocate medical and paramedical staff to face the emergency. Moreover, concerns have been raised that minimally invasive surgery could be a procedure that carries the risk of virus diffusion in the operating theater during surgery. This paper reports clinical recommendations and scientific studies to assist clinicians in this field.
    Keywords covid19
    Language English
    Publishing date 2020-05-14
    Publishing country Germany
    Document type Editorial
    ZDB-ID 2158715-2
    ISSN 1613-2084 ; 1613-2076
    ISSN (online) 1613-2084
    ISSN 1613-2076
    DOI 10.1186/s10397-020-01070-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Laparoscopy in the coronavirus disease 2019 (COVID-19) era

    Angioni, Stefano

    Gynecological Surgery

    2020  Volume 17, Issue 1

    Keywords Obstetrics and Gynaecology ; Surgery ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2158715-2
    ISSN 1613-2084 ; 1613-2076
    ISSN (online) 1613-2084
    ISSN 1613-2076
    DOI 10.1186/s10397-020-01070-7
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Metabolomics analysis in endometriosis patients: is it a step toward the future?

    Angioni, Stefano / Saponara, Stefania / Vitale, Salvatore Giovanni

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

    2023  Volume 39, Issue 1, Page(s) 2227276

    MeSH term(s) Female ; Humans ; Endometriosis ; Metabolomics ; Metabolome
    Language English
    Publishing date 2023-06-28
    Publishing country England
    Document type Editorial
    ZDB-ID 639237-4
    ISSN 1473-0766 ; 0951-3590
    ISSN (online) 1473-0766
    ISSN 0951-3590
    DOI 10.1080/09513590.2023.2227276
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  4. Article: Superficial Peritoneal Endometriosis Vaporization Using a CO

    Di Michele, Stefano / Bramante, Silvia / Angioni, Stefano / Bernassola, Michela / De Vita, Tommaso / Iaccarino, Daniela Anna / Giannoni, Luca / Rosati, Maurizio

    Journal of clinical medicine

    2024  Volume 13, Issue 6

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-03-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: New insights on endometriosis.

    Angioni, Stefano

    Minerva ginecologica

    2017  Volume 69, Issue 5, Page(s) 438–439

    MeSH term(s) Endometriosis/diagnosis ; Endometriosis/pathology ; Endometriosis/surgery ; Female ; Humans ; Laparoscopy/methods ; Quality of Life
    Language English
    Publishing date 2017-05-25
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 80159-8
    ISSN 1827-1650 ; 0026-4784 ; 0325-8793
    ISSN (online) 1827-1650
    ISSN 0026-4784 ; 0325-8793
    DOI 10.23736/S0026-4784.17.04089-8
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  6. Article ; Online: p16 Block Type Overexpression, p53 Wild Type Reactivity, and Cervical Involvement do not Always Exclude the Diagnosis of Primary Endometrial Squamous Cell Carcinoma (PESCC).

    Fanni, Daniela / Gerosa, Clara / Peiretti, Michele / Mais, Valerio / Massa, Elena / Angioni, Stefano / Faa, Gavino

    International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists

    2023  Volume 43, Issue 2, Page(s) 200–201

    MeSH term(s) Female ; Humans ; Tumor Suppressor Protein p53/genetics ; Endometrial Neoplasms/diagnosis ; Endometrial Neoplasms/genetics ; Endometrial Neoplasms/pathology ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/pathology ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Biomarkers, Tumor/genetics
    Chemical Substances Tumor Suppressor Protein p53 ; Cyclin-Dependent Kinase Inhibitor p16 ; Biomarkers, Tumor
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604859-6
    ISSN 1538-7151 ; 0277-1691
    ISSN (online) 1538-7151
    ISSN 0277-1691
    DOI 10.1097/PGP.0000000000000970
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  7. Article ; Online: Safety, Efficacy, and Cost-effectiveness of Organ Suspension in Laparoscopic Gynecologic Surgery. A Retrospective Cohort Study to Validate an Innovative Technique: Laparoscopic Organ Suspension sec. Angioni.

    Angioni, Stefano / Saponara, Stefania / D'Ancona, Gianmarco / Sicilia, Gilda / D'Alterio, Maurizio Nicola / Vitale, Salvatore Giovanni

    Gynecologic and obstetric investigation

    2024  

    Abstract: ... of the Laparoscopic Organ Suspension sec. Angioni, an innovative approach to transient organ suspension (OS ... endometrial cancer, pelvic prolapse, and benign ovarian cysts. The Laparoscopic Organ Suspension sec. Angioni ... Suspension sec. Angioni is introduced as a straightforward, safe, and cost-effective method ...

    Abstract Objectives: This study aims to evaluate the safety, efficacy, and cost-effectiveness of the Laparoscopic Organ Suspension sec. Angioni, an innovative approach to transient organ suspension (OS) in laparoscopic gynecological procedures. Recognizing the need to enhance surgical site access and overcome limitations of existing organ retraction methods, the study investigates a novel, in-theatre constructed OS device.
    Design: This retrospective observational study was conducted from March 2019 to May 2021 and included 330 patients who underwent multiport or single-site-port laparoscopic surgery employing Angioni's Technique for transient pelvic organ suspension.
    Participants/materials, setting, methods: Participants included individuals undergoing surgery for conditions such as endometriosis, ovarian cancer, endometrial cancer, pelvic prolapse, and benign ovarian cysts. The Laparoscopic Organ Suspension sec. Angioni utilizes a segment of a Foley catheter connected to a Polyglactin suture to provide adjustable tension, minimizing the need for reconfiguration during surgery.
    Results: The application of this OS technique resulted in an average suspension time of 1.9 minutes, with no significant difference between senior and junior surgeons. The method proved more time-efficient for posterior peritoneum suspension than other published methods and showed no additional risks of organ damage, bleeding, conversion to laparotomy, or OS-related complications. The secondary outcomes revealed reduced hospital stays and minimal blood loss, highlighting the procedure's overall efficiency.
    Limitations: Given its retrospective and single-center nature, the study's results may not be widely generalizable. Prospective multicentric comparative studies are recommended to to further validate the Angioni's Technique.
    Conclusions: Laparoscopic Organ Suspension sec. Angioni is introduced as a straightforward, safe, and cost-effective method that significantly streamlines the surgical process. Its adaptability and ease of use suggest that it could be a valuable addition to current gynecological surgical practices, with potential implications for increasing efficiency and reducing procedural costs. Future studies are required to confirm these results across diverse clinical environments.
    Language English
    Publishing date 2024-05-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 800003-7
    ISSN 1423-002X ; 0378-7346
    ISSN (online) 1423-002X
    ISSN 0378-7346
    DOI 10.1159/000538787
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  8. Article ; Online: Highlights on Medical Treatment of Uterine Fibroids.

    Angioni, Stefano / D'Alterio, Maurizio N / Daniilidis, Angelos

    Current pharmaceutical design

    2021  Volume 27, Issue 36, Page(s) 3821–3832

    Abstract: Uterine fibroids (leiomyomas or myomas) are the most frequent benign tumors in women. Heavy menstrual bleeding with resultant anemia, dysmenorrhea, chronic pelvic pain, infertility, urinary symptoms and constipation are generally associated with uterine ... ...

    Abstract Uterine fibroids (leiomyomas or myomas) are the most frequent benign tumors in women. Heavy menstrual bleeding with resultant anemia, dysmenorrhea, chronic pelvic pain, infertility, urinary symptoms and constipation are generally associated with uterine fibroids (UFs). Although strategies mainly resort to surgical intervention, medical treatments are considered the first-line treatment to preserve fertility and avoid surgery. The aim of this review is to offer available and the newest medical treatment options for symptomatic UFs. Various medical therapies are now available for women with uterine fibroids, although each therapy has its own advantages and disadvantages. Our topic specifically explores gonadotropin-releasing hormone (GnRH) analogs and selective progesterone receptor modulators (SPRMs), but also provides the reader with useful advice on the therapies for fibroids available after the recent European Medicines Agency (EMA) warning (EMA/160220/2020). The treatment options depend on the personal treatment objectives of the patients, in addition to treatment effectiveness and necessity for recurrent interventions.
    MeSH term(s) Female ; Humans ; Leiomyoma/drug therapy ; Pelvic Pain ; Uterine Neoplasms/drug therapy
    Language English
    Publishing date 2021-01-02
    Publishing country United Arab Emirates
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/1381612826666210101152820
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  9. Article ; Online: Combined Robotic Transanal Transection Single-Stapled Technique in Ultralow Rectal Endometriosis Involvement Associated With Parametrial and Vaginal Infiltration.

    D'Ancona, Gianmarco / Merlot, Benjamin / Denost, Quentin / Angioni, Stefano / Dennis, Thomas / Roman, Horace

    Journal of minimally invasive gynecology

    2023  Volume 31, Issue 4, Page(s) 267–268

    Abstract: Objective: To describe a combined robotic and transanal technique used to treat ultralow rectal endometriosis in a 36-year-old patient with multiple pelvic compartments, which was responsible for infertility, dyspareunia, left sciatic pain, and severe ... ...

    Abstract Objective: To describe a combined robotic and transanal technique used to treat ultralow rectal endometriosis in a 36-year-old patient with multiple pelvic compartments, which was responsible for infertility, dyspareunia, left sciatic pain, and severe dyschezia.
    Design: Surgical video article.
    Setting: The achievement of a perfect bowel anastomosis in patients with low rectal endometriosis could be challenging owing to technical and anatomic limitations [1]. By allowing a right angle rectotomy with a single-stapled anastomosis, the transanal transection single-stapled technique overcomes these technical difficulties ensuring a good-quality anastomosis with an easier correction of postoperative anastomotic leakage when it occurs [2,3].
    Interventions: The surgery starts by splitting the nodule in 3 components according to different anatomic structures involved (parametrium, vagina, and rectum). Parametrial and vaginal fragments are excised as previously described (Supplemental Videos 1) [4]. The rectal involvement is approached following several steps: isolation and cut of inferior mesenteric vessels (inferior mesenteric artery and inferior mesenteric vein) and left colic artery to obtain a proper colon mobilization; transanal rectotomy immediately below the lower limit of the nodule; extraction of the specimen through the anus (Supplemental Videos 2); proximal bowel segment transection 1 cm above the upper limit of the nodule; introduction of circular stapler anvil into the sigmoid colon; placement of 2 purse string to secure the anvil and at distal rectal cuff, respectively; connection of the anvil to the shoulder of circular stapler; stapler closing and firing with coloanal anastomosis formation; stapled line reinforcement by stitching; and integrity anastomosis test (Supplemental Videos 3). No preventive diverting stoma was performed in accordance with our policy [5].
    Conclusions: Although no data are yet available in patients with endometriosis, the use of transanal transection single-stapled technique may be an interesting approach in patients with very low rectal endometriosis involvement.
    MeSH term(s) Female ; Humans ; Adult ; Endometriosis/surgery ; Endometriosis/complications ; Robotic Surgical Procedures ; Rectum/surgery ; Rectal Diseases/surgery ; Rectal Diseases/complications ; Anastomosis, Surgical/methods ; Vagina/surgery ; Laparoscopy/methods ; Rectal Neoplasms/surgery
    Language English
    Publishing date 2023-12-29
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2186934-0
    ISSN 1553-4669 ; 1553-4650
    ISSN (online) 1553-4669
    ISSN 1553-4650
    DOI 10.1016/j.jmig.2023.12.012
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  10. Article: A New Methodology to Assess Fallopian Tubes Microbiota and Its Impact on Female Fertility.

    Vitale, Salvatore Giovanni / Carugno, Jose / D'Alterio, Maurizio Nicola / Mikuš, Mislav / Patrizio, Pasquale / Angioni, Stefano

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 6

    Abstract: Tubal factor is an important contributor to female infertility, and the current diagnostic approaches cannot correctly identify many subtle causes of tubal dysfunction. While it is known that the most common cause of tubal factor infertility is pelvic ... ...

    Abstract Tubal factor is an important contributor to female infertility, and the current diagnostic approaches cannot correctly identify many subtle causes of tubal dysfunction. While it is known that the most common cause of tubal factor infertility is pelvic inflammatory disease (PID), creating critical alterations of the tubal epithelium, little attention has been devoted to understanding the tubal modifications caused by the resident microbial population and their interaction with the surrounding tubal epithelium. Furthermore, most of these samples are obtained by traumatic procedures such as direct sampling during laparoscopy using a cytobrush. However, as in any other organ of the female genital tract, the microbiota environment of the fallopian tube plays an essential role in maintaining tubal functioning, counteracting the pathogenic effect of acquired microbes. Consequentially, to better analyze the tubal microbiota without causing anatomical and/or functional alteration of the fallopian tube and preserving fertility, the hysteroscopic approach might be the method of choice, guarantying maximal integrity of the uterine cavity and tubal lumen. Here we describe our plan for using atraumatic hysteroscopic sampling methods to investigate the correlation between tubal microbiota and female infertility.
    Language English
    Publishing date 2022-06-02
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12061375
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