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  1. Article: Influence of Individual-technology-task-environment Fit on University Student Online Learning Performance: The Mediating Role of Behavioral, Emotional, and Cognitive Engagement.

    Liu, Kaifeng / Yao, Jingtao / Tao, Da / Yang, Tianrui

    Education and information technologies

    2023  , Page(s) 1–20

    Abstract: The present study aimed to examine whether and to what extent university student online learning performance was influenced by individual-technology fit (ITF), task-technology fit (TTF), environment-technology fit (ETF), and whether the influence was ... ...

    Abstract The present study aimed to examine whether and to what extent university student online learning performance was influenced by individual-technology fit (ITF), task-technology fit (TTF), environment-technology fit (ETF), and whether the influence was mediated by their behavioral, emotional, and cognitive engagement. A theoretical research model was developed by integrating the extended TTF theory and student engagement framework. The validity of the model was assessed using a partial least squares structural equation modeling approach based on data collected from 810 university students. Student learning performance was influenced by TTF (β = 0.25,
    Language English
    Publishing date 2023-05-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2001930-0
    ISSN 1573-7608 ; 1360-2357
    ISSN (online) 1573-7608
    ISSN 1360-2357
    DOI 10.1007/s10639-023-11833-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Rare Root Canal Configuration of a Maxillary Second Molar with Fused C-shaped Buccal Root and Five Canals: A Case Report and Review of literature.

    Liu, Dan / Qiu, Lihong / Yu, Jingtao

    Iranian endodontic journal

    2023  Volume 14, Issue 3, Page(s) 225–231

    Abstract: Having a thorough knowledge of root canal configuration is essential for a successful endodontic treatment. Clinicians should always pay attention to the unusual canal configuration so as to avoid missing extra canals. This paper describes a non-surgical ...

    Abstract Having a thorough knowledge of root canal configuration is essential for a successful endodontic treatment. Clinicians should always pay attention to the unusual canal configuration so as to avoid missing extra canals. This paper describes a non-surgical retreatment of a maxillary second molar with two missing root canals; diagnosed by cone-beam computed tomographic (CBCT) imaging. The tooth had three roots and five canals: a C-shaped buccal root fused by mesiobuccal (MB) and distobuccal (DB) roots with three canals (CBCT scanning showed that the second MB canal was closer to the palatal than the buccal side), a mesiopalatal root with one canal, and a distopalatal root with one canal. The purpose of this case report is to remind clinicians of the importance of anatomical variations, and thus, detection of extra canals.
    Language English
    Publishing date 2023-01-18
    Publishing country Iran
    Document type Case Reports
    ZDB-ID 2684659-7
    ISSN 2008-2746 ; 2008-2746
    ISSN (online) 2008-2746
    ISSN 2008-2746
    DOI 10.22037/iej.v14i3.23900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Water Uptake Tradeoffs of Dominant Shrub Species in the Coastal Wetlands of the Yellow River Delta, China.

    Zhu, Jinfang / Liu, Jingtao / Li, Junsheng / Zhao, Caiyun / Sun, Jingkuan

    Frontiers in plant science

    2022  Volume 13, Page(s) 935025

    Abstract: ... Tamarix ... ...

    Abstract Tamarix chinensis
    Language English
    Publishing date 2022-06-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.935025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ferroptosis-Related Gene SLC1A5 Is a Novel Prognostic Biomarker and Correlates with Immune Microenvironment in HBV-Related HCC

    Hanwen Su / Youyi Liu / Jingtao Huang

    Journal of Clinical Medicine, Vol 12, Iss 1715, p

    2023  Volume 1715

    Abstract: 1) Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with limited treatment satisfaction. Finding new therapeutic targets has remained a major challenge. Ferroptosis is an iron-dependent cell death program that plays ...

    Abstract (1) Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with limited treatment satisfaction. Finding new therapeutic targets has remained a major challenge. Ferroptosis is an iron-dependent cell death program that plays a regulatory role in HBV infection and HCC development. It is necessary to classify the roles of ferroptosis or ferroptosis-related genes (FRGs) in HBV-related HCC progression. (2) Methods: We conducted a matched case–control study from the TCGA database, retrospectively collecting demographic data and common clinical indicators from all subjects. The Kaplan–Meier curve, univariate and multivariate cox regression analysis of the FRGs were used to explore the risk factors for HBV-related HCC. The CIBERSORT algorithm and TIDE algorithm were executed to evaluate the functions of FRGs in the tumor-immune environment. (3) Results: A total of 145 HBV-positive HCC patients and 266 HBV-negative HCC patients were enrolled in our study. Four ferroptosis related genes (FANCD2, CS, CISD1 and SLC1A5) were positively correlated with the progression of HBV-related HCC. Among them, SLC1A5 was an independent risk factor for HBV-related HCC, and correlated with poor prognosis, advanced progression and an immunosuppression microenvironment. (4) Conclusions: Here, we revealed that a ferroptosis-related gene, SLC1A5, may be an excellent predictor of HBV-related HCC and may provide insight into the development of innovative possible therapeutic techniques.
    Keywords HBV ; HCC ; SLC1A5 ; ferroptosis-related gene ; tumor microenvironment ; Medicine ; R
    Subject code 570
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Retraction notice to "Emodin protects hyperglycemia-induced injury in PC-12 cells by up-regulation of miR-9" [Mol. Cell. Endocrinol. 474 (2018) 194-200].

    Fan, Lei / Zhang, Huifeng / Li, Xiaobin / Yang, Guang / Ru, Jingtao / Liu, Tao

    Molecular and cellular endocrinology

    2023  Volume 565, Page(s) 111782

    Language English
    Publishing date 2023-02-17
    Publishing country Ireland
    Document type Journal Article ; Retraction of Publication
    ZDB-ID 187438-x
    ISSN 1872-8057 ; 0303-7207
    ISSN (online) 1872-8057
    ISSN 0303-7207
    DOI 10.1016/j.mce.2022.111782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1127: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  6. Article: Ferroptosis-Related Gene SLC1A5 Is a Novel Prognostic Biomarker and Correlates with Immune Microenvironment in HBV-Related HCC.

    Su, Hanwen / Liu, Youyi / Huang, Jingtao

    Journal of clinical medicine

    2023  Volume 12, Issue 5

    Abstract: 1) Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with limited treatment satisfaction. Finding new therapeutic targets has remained a major challenge. Ferroptosis is an iron-dependent cell death program that plays ...

    Abstract (1) Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with limited treatment satisfaction. Finding new therapeutic targets has remained a major challenge. Ferroptosis is an iron-dependent cell death program that plays a regulatory role in HBV infection and HCC development. It is necessary to classify the roles of ferroptosis or ferroptosis-related genes (FRGs) in HBV-related HCC progression. (2) Methods: We conducted a matched case-control study from the TCGA database, retrospectively collecting demographic data and common clinical indicators from all subjects. The Kaplan-Meier curve, univariate and multivariate cox regression analysis of the FRGs were used to explore the risk factors for HBV-related HCC. The CIBERSORT algorithm and TIDE algorithm were executed to evaluate the functions of FRGs in the tumor-immune environment. (3) Results: A total of 145 HBV-positive HCC patients and 266 HBV-negative HCC patients were enrolled in our study. Four ferroptosis related genes (FANCD2, CS, CISD1 and SLC1A5) were positively correlated with the progression of HBV-related HCC. Among them, SLC1A5 was an independent risk factor for HBV-related HCC, and correlated with poor prognosis, advanced progression and an immunosuppression microenvironment. (4) Conclusions: Here, we revealed that a ferroptosis-related gene, SLC1A5, may be an excellent predictor of HBV-related HCC and may provide insight into the development of innovative possible therapeutic techniques.
    Language English
    Publishing date 2023-02-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12051715
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice.

    Xianchu, Liu / Ming, Liu / Changhao, Cheng / Beiwang, Deng / Jingtao, Xie

    Iranian journal of basic medical sciences

    2022  Volume 24, Issue 12, Page(s) 1695–1701

    Abstract: Objectives: Diabetes is fundamentally connected with the inability of skeletal muscle. Sinapic acid (SA) has multiple biologic functions and is diffusely utilized in diabetic complications. The purpose of this study was to explore the potential ... ...

    Abstract Objectives: Diabetes is fundamentally connected with the inability of skeletal muscle. Sinapic acid (SA) has multiple biologic functions and is diffusely utilized in diabetic complications. The purpose of this study was to explore the potential improvement effect and mechanisms of SA in streptozotocin (STZ)-induced diabetic muscle atrophy.
    Materials and methods: The model of diabetic mice was established by intraperitoneal STZ (200 mg/kg) to evaluate the treatment effect of SA (40 mg/kg/d for 8 weeks) on muscle atrophy. Muscle fiber size was assessed by Hematoxylin and Eosin (HE) staining. Muscle force was measured by a dynamometer. Biochemical parameters were tested by using corresponding commercial kits. The expressions of Atrogin-1, MuRF-1, nuclear respiratory factor 1 (NRF-1), peroxisome proliferative activated receptor gamma coactivator 1 alpha (PGC-1α), CHOP, GRP-78, BAX, and BCL-2 were detected by Western blot.
    Results: Our data demonstrated that SA increased fiber size and weight of gastrocnemius, and enhanced grip strength to alleviate diabetes-induced muscle atrophy. In serum, SA restrained creatine kinase (CK), lactate dehydrogenase (LDH), malondialdehyde (MDA), tumor necrosis factor (TNF-a), and interleukin 6 (IL-6) levels, while enhancing total anti-oxidant capacity (T-AOC), superoxide dismutase (SOD) and catalase (CAT) levels to improve muscle injury. In gastrocnemius, SA promoted NRF-1, PGC-1α, and BCL-2 expressions, while inhibiting Atrogin-1, MuRF-1, CHOP, GRP-87, and BAX expressions.
    Conclusion: SA protected against diabetes-induced gastrocnemius injury via improvement of mitochondrial function, endoplasmic reticulum (ER) stress, and apoptosis, and could be developed to prevent and treat diabetic muscle atrophy.
    Language English
    Publishing date 2022-03-21
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2500485-2
    ISSN 2008-3874 ; 2008-3866
    ISSN (online) 2008-3874
    ISSN 2008-3866
    DOI 10.22038/IJBMS.2021.60324.13370
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  8. Article: Identification of a Novel Prognostic Gene Signature From the Immune Cell Infiltration Landscape of Osteosarcoma.

    Fan, Lei / Ru, Jingtao / Liu, Tao / Ma, Chao

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 718624

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-09-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.718624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Polarized Th2 cells attenuate high-fat-diet induced obesity through the suppression of lipogenesis.

    Dong, Lijun / Gao, Jingtao / Yu, Lu / Liu, Shibo / Zhao, Yuxin / Zhang, Wen / Liang, Yinming / Wang, Hui

    BMC immunology

    2024  Volume 25, Issue 1, Page(s) 4

    Abstract: Immune cells, such as macrophages, B cells, neutrophils and T cell subsets, have been implicated in the context of obesity. However, the specific role of Th2 cells in adipose tissue function has remained elusive. Eight-week-old male ... ...

    Abstract Immune cells, such as macrophages, B cells, neutrophils and T cell subsets, have been implicated in the context of obesity. However, the specific role of Th2 cells in adipose tissue function has remained elusive. Eight-week-old male CD3ε
    MeSH term(s) Male ; Animals ; Mice ; Diet, High-Fat/adverse effects ; Lipogenesis ; Th2 Cells ; Obesity/therapy ; Adoptive Transfer
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041500-X
    ISSN 1471-2172 ; 1471-2172
    ISSN (online) 1471-2172
    ISSN 1471-2172
    DOI 10.1186/s12865-024-00598-z
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  10. Article ; Online: Single-cell RNA sequencing reveals aberrant sphingolipid metabolism in non-small cell lung cancer impacts tumor-associated macrophages and stimulates angiogenesis via macrophage inhibitory factor signaling.

    Shen, Luyan / Liu, Jingtao / Hu, Fengling / Fang, Yifan / Wu, Yaya / Zhao, Wei / Ma, Shaohua

    Thoracic cancer

    2024  

    Abstract: Background: Sphingolipids not only serve as structural components for maintaining cell membrane fluidity but also function as bioactive molecules involved in cell signaling and the regulation of various biological processes. Their pivotal role in cancer ...

    Abstract Background: Sphingolipids not only serve as structural components for maintaining cell membrane fluidity but also function as bioactive molecules involved in cell signaling and the regulation of various biological processes. Their pivotal role in cancer cell development, encompassing cancer cell proliferation, migration, angiogenesis, and metastasis, has been a focal point for decades. However, the contribution of sphingolipids to the complexity of tumor microenvironment promoting cancer progression has been rarely investigated.
    Methods: Through the integration of publicly available bulk RNA-seq and single-cell RNA-seq data, we conducted a comprehensive analysis to compare the transcriptomic features between tumors and adjacent normal tissues, thus elucidating the intricacies of the tumor microenvironment (TME).
    Results: Disparities in sphingolipid metabolism (SLM)-associated genes were observed between normal and cancerous tissues, with the TME characterized by the enrichment of sphingolipid signaling in macrophages. Cellular interaction analysis revealed robust communication between macrophages and cancer cells exhibiting low SLM, identifying the crucial ligand-receptor pair, macrophage inhibitory factor (MIF)-CD74. Pseudo-time analysis unveiled the involvement of SLM in modulating macrophage polarization towards either M1 or M2 phenotypes. Categorizing macrophages into six subclusters based on gene expression patterns and function, the SPP1+ cluster, RGS1+ cluster, and CXCL10+ cluster were likely implicated in sphingolipid-induced M2 macrophage polarization. Additionally, the CXCL10+, AGER+, and FABP4+ clusters were likely to be involved in angiogenesis through their interaction with endothelial cells.
    Conclusion: Based on multiple scRNA-seq datasets, we propose that a MIF-targeted strategy could potentially impede the polarization from M1 to M2 and impair tumor angiogenesis in low-SLM non-small cell lung cancer (NSCLC), demonstrating its potent antitumor efficacy.
    Language English
    Publishing date 2024-04-08
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2625856-0
    ISSN 1759-7714 ; 1759-7706
    ISSN (online) 1759-7714
    ISSN 1759-7706
    DOI 10.1111/1759-7714.15283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6921: Show issues Location:
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