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  1. Article ; Online: Ying-Zu Huang, 1966-2021.

    Rothwell, John C / Chen, Rou-Shayn

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    2022  

    Language English
    Publishing date 2022-05-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1463630-x
    ISSN 1872-8952 ; 0921-884X ; 1388-2457
    ISSN (online) 1872-8952
    ISSN 0921-884X ; 1388-2457
    DOI 10.1016/j.clinph.2022.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: In Regard to Ying Li et al.

    Wang, Tao / Tian, Guangyu / Chen, Xiaojun

    International journal of radiation oncology, biology, physics

    2021  Volume 111, Issue 2, Page(s) 581

    Language English
    Publishing date 2021-08-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2021.06.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Ying and Yang balance: Transcription factors OsNAC2 and OsEREBP1 synergistically regulate plant immunity.

    Fang, Yuan / Chen, Jian

    Plant physiology

    2024  

    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208914-2
    ISSN 1532-2548 ; 0032-0889
    ISSN (online) 1532-2548
    ISSN 0032-0889
    DOI 10.1093/plphys/kiae031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: SIRT1/P53 in retinal pigment epithelial cells in diabetic retinopathy: a gene co-expression analysis and He-Ying-Qing-Re formula treatment.

    Zhang, Shuyan / Wu, Jiajun / Wang, Leilei / Mu, Lin / Xu, Xiaoyu / Li, Jiahui / Tang, Guoyi / Chen, Guang / Zhang, Cheng / Zhang, Yinjian / Feng, Yibin

    Frontiers in molecular biosciences

    2024  Volume 11, Page(s) 1366020

    Abstract: ... visual impairment or blindness. He-Ying-Qing-Re formula (HF), a traditional Chinese medicinal concoction, has been ...

    Abstract Objective: Diabetic retinopathy (DR) is a severe diabetic complication that leads to severe visual impairment or blindness. He-Ying-Qing-Re formula (HF), a traditional Chinese medicinal concoction, has been identified as an efficient therapy for DR with retinal vascular dysfunction for decades and has been experimentally reported to ameliorate retinal conditions in diabetic mice. This study endeavors to explore the therapeutic potential of HF with key ingredients in DR and its underlying novel mechanisms.
    Methods: Co-expression gene modules and hub genes were calculated by weighted gene co-expression network analysis (WGCNA) based on transcriptome sequencing data from high-glucose-treated adult retinal pigment epithelial cell line-19 (ARPE-19). The chromatographic fingerprint of HF was established by ultra-performance liquid chromatography coupled with high-resolution mass spectrometry (UPLC-Q-TOF-MS). The molecular affinity of the herbal compound was measured by molecular docking. Reactive oxygen species (ROS) was measured by a DCFDA/H2DCFDA assay. Apoptosis was detected using the TUNEL Assay Kit, while ELISA, Western blot, and real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) were used for detecting the cytokine, protein, and mRNA expressions, respectively.
    Results: Key compounds in HF were identified as luteolin, paeoniflorin, and nobiletin. For WGCNA, ME-salmon ("protein deacetylation") was negatively correlated with ME-purple ("oxidative impairment") in high-glucose-treated ARPE-19. Luteolin has a high affinity for SIRT1 and P53, as indicated by molecular docking. Luteolin has a hypoglycemic effect on type I diabetic mice. Moreover, HF and luteolin suppress oxidative stress production (ROS and MDA), inflammatory factor expression (IL-6, TNF-α, IL1-β, and MCP-1), and apoptosis, as shown in the
    Conclusion: Using HF and its active compound luteolin as therapeutic agents offers a promising approach to diabetic retinopathy treatment. It primarily suppressed protein acetylation and oxidative stress via the SIRT1/P53 pathway in retinal pigment epithelial cells.
    Language English
    Publishing date 2024-04-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2024.1366020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Transcriptome analysis reveals differentially expressed genes involved in somatic embryogenesis and podophyllotoxin biosynthesis of Sinopodophyllum hexandrum (Royle) T. S. Ying.

    Guo, Shenghu / Chen, Yuchao / Zhu, Yongxing / Tian, Mei

    Protoplasma

    2023  Volume 260, Issue 4, Page(s) 1221–1232

    Abstract: Sinopodophyllum hexandrum (Royle) T. S. Ying, an important source of podophyllotoxin (PTOX), has ...

    Abstract Sinopodophyllum hexandrum (Royle) T. S. Ying, an important source of podophyllotoxin (PTOX), has become a rare and endangered plant because of over-harvesting. Somatic embryogenesis (SE) is the main way of seedling rapid propagation and germplasm enhancement, but the regeneration of S. hexandrum has not been well established, and the PTOX biosynthesis abilities at different SE stages remain unclear. Therefore, it is extremely important to elucidate the SE mechanism of S. hexandrum and clarify the biosynthesis variation of PTOX. In this study, the transcriptomes of S. hexandrum at different SE stages were sequenced, the contents of PTOX and 4'-demethylepipodophyllotoxin were assayed, and the transcript expression patterns were validated by qRT-PCR. The results revealed that plant hormone (such as auxins, abscisic acid, zeatin, and gibberellins) related pathways were significantly enriched among different SE stages, indicating these plant hormones play important roles in SE of S. hexandrum; the expression levels of a series of PTOX biosynthesis related genes as well as PTOX and 4'-demethylepipodophyllotoxin contents were much higher in embryogenic callus stage than in the other stages, suggesting embryogenic callus stage has the best PTOX biosynthesis ability among different SE stages. This study will contribute to germplasm conservation and fast propagation of S. hexandrum, and facilitate the production of PTOX.
    MeSH term(s) Podophyllotoxin ; Gene Expression Profiling ; Berberidaceae/genetics ; Transcriptome/genetics ; Plant Growth Regulators ; Plant Somatic Embryogenesis Techniques
    Chemical Substances 4'-demethylepipodophyllotoxin (X0S6I23X6L) ; Podophyllotoxin (L36H50F353) ; Plant Growth Regulators
    Language English
    Publishing date 2023-02-25
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 123809-7
    ISSN 1615-6102 ; 0033-183X
    ISSN (online) 1615-6102
    ISSN 0033-183X
    DOI 10.1007/s00709-023-01843-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Anticoccidial Effect of Herbal Powder "Shi Ying Zi" in Chickens Infected with

    Song, Xu / Li, Yunhe / Chen, Shufan / Jia, Renyong / Huang, Yongyuan / Zou, Yuanfeng / Li, Lixia / Zhao, Xinxin / Yin, Zhongqiong

    Animals : an open access journal from MDPI

    2020  Volume 10, Issue 9

    Abstract: Coccidiosis is one of the most economically important diseases affecting the poultry industry. Currently, anticoccidial drugs used in veterinary clinics show many deficiencies, and new control measures are urgently needed. This study presents an ... ...

    Abstract Coccidiosis is one of the most economically important diseases affecting the poultry industry. Currently, anticoccidial drugs used in veterinary clinics show many deficiencies, and new control measures are urgently needed. This study presents an anticoccidial herbal powder "Shi Yin Zi", which consists of
    Language English
    Publishing date 2020-08-24
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani10091484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The complete chloroplast genome of Sinopodophyllum hexandrum Ying (Berberidaceae).

    Meng, Lihua / Liu, Ruijuan / Chen, Jianbing / Ding, Chenxu

    Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis

    2017  Volume 28, Issue 3, Page(s) 342–343

    Abstract: The complete nucleotide sequence of the Sinopodophyllum hexandrum Ying chloroplast genome (cpDNA ...

    Abstract The complete nucleotide sequence of the Sinopodophyllum hexandrum Ying chloroplast genome (cpDNA) was determined based on next-generation sequencing technologies in this study. The genome was 157 203 bp in length, containing a pair of inverted repeat (IRa and IRb) regions of 25 960 bp, which were separated by a large single-copy (LSC) region of 87 065 bp and a small single-copy (SSC) region of 18 218 bp, respectively. The cpDNA contained 148 genes, including 96 protein-coding genes, 8 ribosomal RNA genes, and 44 tRNA genes. In these genes, eight harbored a single intron, and two (ycf3 and clpP) contained a couple of introns. The cpDNA AT content of S. hexandrum cpDNA is 61.5%.
    Language English
    Publishing date 2017-05
    Publishing country England
    Document type Journal Article
    ISSN 2470-1408
    ISSN (online) 2470-1408
    DOI 10.3109/19401736.2015.1122773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Han-la-ying-zhong-cao-yao-ming-da-cidian

    Chen, Fa-Wen

    = A comprehensive Chinese Latin English dictionary of the names of Chinese herbal medicines

    1998  

    Title variant A comprehensive Chinese Latin English dictionary of the names of Chinese herbal medicines ; Han la ying zhong cao yao ming da cidian ; Han-la-ying-chung-ts'ao-yao-ming-ta-t'zu-tien ; A comprehensive Chinese-Latin-English dictionary of the names of Chinese herbal medicines
    Author's details zhubian Chen Fa-Wen
    Language Chinese ; Latin ; English
    Size 137, 1194 S.
    Publisher Shi-jie-tushu-ban-xian-gongsi
    Publishing place S.l.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT012768496
    ISBN 7-5062-3971-X ; 978-7-5062-3971-4
    Database Catalogue ZB MED Medicine, Health

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  9. Article: [Sugar and sugar alcohols in infants Ying Yang Bao based on derivatization and gas chromatography-mass spectrometry].

    Ma, Yan / Cheng, Jiali / Tang, Yanbin / Gong, Zhaolong / Shen, Shi / Chen, Chen / Zhang, Xuesong

    Wei sheng yan jiu = Journal of hygiene research

    2020  Volume 49, Issue 3, Page(s) 442–446

    Abstract: ... of seven sugars and sugar alcohols in infants Ying Yang Bao nutritional supplements.: Methods ...

    Abstract Objective: To establish a gas chromatography-mass spectrometry(GC-MS) method for determination of seven sugars and sugar alcohols in infants Ying Yang Bao nutritional supplements.
    Methods: The samples were extracted with pure water and diluted with 95% ethanol. After being dried by nitrogen, methoxyamine hydrochloride oxime was dissolved in pyridine and derivatized by MSTFA. The capillary column TG-5 Ms(30 m×0. 25 mm, 0. 25 μm) was used for determination by GC-MS.
    Results: The limits of detection(LODs)were 1. 0-3. 0 mg/g and the limits of quantification(LOQs)were 3. 3-10. 0 mg/g. The average recoveries of seven kinds of sugar and sugar alcohols were 86. 7%-96. 7%, and the relative standard deviation was less than 5. 1%(n=6). The contents of seven sugars and sugar alcohols in soybean matrix nutritional supplements were determined in the range of 0. 25-13. 70 g/100 g, which was consistent with the nutrition label of the products.
    Conclusion: The method is convenient, mild and fit for batch sample analysis.
    MeSH term(s) Gas Chromatography-Mass Spectrometry ; Limit of Detection ; Sugar Alcohols/analysis ; Sugars
    Chemical Substances Sugar Alcohols ; Sugars
    Language Chinese
    Publishing date 2020-07-21
    Publishing country China
    Document type Journal Article
    ZDB-ID 1050909-4
    ISSN 1000-8020
    ISSN 1000-8020
    DOI 10. 19813/j. cnki. weishengyanjiu. 2020. 03. 016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Erratum: FENG LIN, ZHI-YING CHEN, KHIN MAR MYINT & XIAO-YONG CHEN (2023) Paracanthocobitis putaoensis, a new loach species (Cypriniformes: Nemacheilidae) from the Irrawaddy basin in northern Myanmar Zootaxa, 5227 (2): 265-278.

    Lin, Feng / Chen, Zhiying / Myint, Khin Mar / Chen, Xiaoyong

    Zootaxa

    2023  Volume 5297, Issue 4, Page(s) 600

    Language English
    Publishing date 2023-06-06
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5297.4.10
    Database MEDical Literature Analysis and Retrieval System OnLINE

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