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  1. Article ; Online: Is Russia's Research Ethics Culture Reliable?

    Litewka, Sergio G / Moreno, Jonathan D

    Ethics & human research

    2022  Volume 44, Issue 6, Page(s) 39–42

    Abstract: The Russian invasion of Ukraine has led to the imposition of economic sanctions intended to isolate Russia from much of global commerce, which implicitly includes the medical research enterprise. The prospect of ongoing isolation of Russia's substantial ... ...

    Abstract The Russian invasion of Ukraine has led to the imposition of economic sanctions intended to isolate Russia from much of global commerce, which implicitly includes the medical research enterprise. The prospect of ongoing isolation of Russia's substantial research enterprise raises issues related to but distinct from the more familiar problem of corruption. In this paper, we identify reasons that the culture of research ethics in Russia may have been weak even before the war, contributing to hard questions about its future role in the global clinical research community.
    MeSH term(s) Humans ; Russia ; Commerce ; Ethics, Research ; Ukraine
    Language English
    Publishing date 2022-09-13
    Publishing country United States
    Document type Journal Article
    ISSN 2578-2363
    ISSN (online) 2578-2363
    DOI 10.1002/eahr.500145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Latin American healthcare systems in times of pandemic.

    Litewka, Sergio G / Heitman, Elizabeth

    Developing world bioethics

    2020  Volume 20, Issue 2, Page(s) 69–73

    Abstract: The COVID- 19 pandemic is a critical test for the already overburdened and mostly underfunded public healthcare systems of Latin America. In a region that suffers from severe inequalities, public healthcare systems are the only source of medical care for ...

    Abstract The COVID- 19 pandemic is a critical test for the already overburdened and mostly underfunded public healthcare systems of Latin America. In a region that suffers from severe inequalities, public healthcare systems are the only source of medical care for a large sector of the population who work in the informal economy or are unemployed. State-run hospitals and clinics are already overstressed by continuous demand for treatment of vector-borne diseases and community-acquired infections as well as high rates of non-communicable diseases. Ideological misconceptions and denial among Latin America's political leaders prevented timely preparations for the pandemic and added to chronic governance problems. As ethical expertise in Latin America focuses on research ethics, few hospitals in the region have functioning clinical ethics committees or clinical ethics policy, forcing healthcare personnel to make excruciating treatment decisions in an environment dominated by material scarcity and public distrust. This essay examines the emergence of COVID-19 in Latin America and the serious challenge that it poses for Latin America's public healthcare systems.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Health Policy ; Health Services Needs and Demand ; Humans ; Latin America/epidemiology ; National Health Programs ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Public Health Administration ; Quarantine ; Resource Allocation ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2049034-3
    ISSN 1471-8847 ; 1471-8731
    ISSN (online) 1471-8847
    ISSN 1471-8731
    DOI 10.1111/dewb.12262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Latin American healthcare systems in times of pandemic

    Litewka, Sergio G / Heitman, Elizabeth

    Dev World Bioeth

    Abstract: The COVID- 19 pandemic is a critical test for the already overburdened and mostly underfunded public healthcare systems of Latin America. In a region that suffers from severe inequalities, public healthcare systems are the only source of medical care for ...

    Abstract The COVID- 19 pandemic is a critical test for the already overburdened and mostly underfunded public healthcare systems of Latin America. In a region that suffers from severe inequalities, public healthcare systems are the only source of medical care for a large sector of the population who work in the informal economy or are unemployed. State-run hospitals and clinics are already overstressed by continuous demand for treatment of vector-borne diseases and community-acquired infections as well as high rates of non-communicable diseases. Ideological misconceptions and denial among Latin America's political leaders prevented timely preparations for the pandemic and added to chronic governance problems. As ethical expertise in Latin America focuses on research ethics, few hospitals in the region have functioning clinical ethics committees or clinical ethics policy, forcing healthcare personnel to make excruciating treatment decisions in an environment dominated by material scarcity and public distrust. This essay examines the emergence of COVID-19 in Latin America and the serious challenge that it poses for Latin America's public healthcare systems.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #46873
    Database COVID19

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  4. Article: [No title information]

    Litewka, Sergio G

    Acta bioethica

    2011  Volume 16, Issue 2, Page(s) 148–154

    Abstract: Argentina ha sido un campo fértil para los intentos de reforma del sector salud, en la búsqueda por mejorar la calidad de sus servicios y, consecuentemente, la accesibilidad y la equidad del mismo. Los resultados obtenidos no han sido proporcionales a ... ...

    Title translation QUALITY, HEALTH SYSTEM AND GOVERNANCE. THE ARGENTINEAN CASE.
    Abstract Argentina ha sido un campo fértil para los intentos de reforma del sector salud, en la búsqueda por mejorar la calidad de sus servicios y, consecuentemente, la accesibilidad y la equidad del mismo. Los resultados obtenidos no han sido proporcionales a los esfuerzos desarrollados. Aunque la bioética debería, como forma de reflexión interdisciplinaria, participar en la fundamentación de nuevas políticas sanitarias y sus efectos sobre los usuarios, parece haber permanecido ajena, en general, a los graves problemas derivados de la corrupción, prefiriendo enfocarse en cuestiones vinculadas a planteos abstractos de justicia y solidaridad, atribuyendo los fracasos a la imposición de modelos económicos foráneos.
    Language Spanish
    Publishing date 2011-06-02
    Publishing country Chile
    Document type Journal Article
    ZDB-ID 2122084-0
    ISSN 1726-569X ; 0717-5906
    ISSN (online) 1726-569X
    ISSN 0717-5906
    DOI 10.4067/S1726-569X2010000200007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: CALIDAD, SISTEMA DE SALUD Y GOBERNANZA

    Sergio G Litewka

    Acta Bioethica, Vol 16, Iss 2, Pp 148-

    EL CASO ARGENTINO QUALIDADE, SISTEMA DE SAÚDE E GOVERNANÇA: O CASO ARGENTINO QUALITY, HEALTH SYSTEM AND GOVERNANCE: THE ARGENTINEAN CASE

    2010  Volume 154

    Abstract: Argentina ha sido un campo fértil para los intentos de reforma del sector salud, en la búsqueda por mejorar la calidad de sus servicios y, consecuentemente, la accesibilidad y la equidad del mismo. Los resultados obtenidos no han sido proporcionales a ... ...

    Abstract Argentina ha sido un campo fértil para los intentos de reforma del sector salud, en la búsqueda por mejorar la calidad de sus servicios y, consecuentemente, la accesibilidad y la equidad del mismo. Los resultados obtenidos no han sido proporcionales a los esfuerzos desarrollados. Aunque la bioética debería, como forma de reflexión interdisciplinaria, participar en la fundamentación de nuevas políticas sanitarias y sus efectos sobre los usuarios, parece haber permanecido ajena, en general, a los graves problemas derivados de la corrupción, prefiriendo enfocarse en cuestiones vinculadas a planteos abstractos de justicia y solidaridad, atribuyendo los fracasos a la imposición de modelos económicos foráneos. Argentina tem sido um campo fértil para os intentos de reforma do setor saúde, na busca pela melhoria da qualidade de seus serviços e, consequentemente, melhoria de sua acessibilidade e equidade. Os resultados obtidos não têm sido proporcionais aos esforços desenvolvidos. Ainda que a bioética devesse, como forma de reflexão interdisciplinar, participar na fundamentação de novas políticas sanitárias e de seus efeitos sobre os usuários, estas parecem ter permanecido alheias, em geral, aos graves problemas derivados da corrupção, preferindo-se enfocar questões vinculadas a propostas abstratas de justiça e solidariedade, atribuindo os fracassos à imposição de modelos econômicos estrangeiros. Argentina had been a fertile ground for reform attempts, focusing in the quality of its health services and subsequently, improving the accessibility and equity to the system. Even though bioethics, as a tool for interdisciplinary reflection, should had been a participant for the foundations of health policies and the impact on its users, it seems that local bioethics had omitted the deleterious consequences created by the lack of governance and corruption on the Argentinean public and social security healthcare systems, choosing instead for focusing in blurry discussions about universal issues related to solidarity and justice, blaming for the failures to the imposition of foreign economical models.
    Keywords Argentina ; corrupción ; salud ; ética ; corrupção ; saúde ; Argentine ; corruption ; health ; ethics ; Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language Spanish
    Publisher Centro Interdisciplinario de Estudios en Bioética, Universidad de Chile
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Vitamin D deficiency among patients with pulmonary hypertension.

    Atamañuk, Andrés N / Litewka, Diego F / Baratta, Sergio J / Seropian, Ignacio M / Perez Prados, Graciela / Payaslian, Miguel O / Ortiz Fragola, Juan P / Escribano Subias, Pilar

    BMC pulmonary medicine

    2019  Volume 19, Issue 1, Page(s) 258

    Abstract: Background: There is little information about vitamin D (Vit D) deficiency in patients with pulmonary hypertension (PH). The objective of this study was: 1) compare Vit D levels between patients with PH, left ventricular failure (LVF) and healthy ... ...

    Abstract Background: There is little information about vitamin D (Vit D) deficiency in patients with pulmonary hypertension (PH). The objective of this study was: 1) compare Vit D levels between patients with PH, left ventricular failure (LVF) and healthy subjects (HS); 2) correlate, in patients with PH, Vit D levels with prognosis-related variables, such as the 6-min walk test (6MWT).
    Methods: Vitamin D levels were measured in a cross-sectional study in 126 patients from one of three groups: patients with PH (n = 53), patients with LVF (n = 42) and healthy subjects (n = 31). In all groups, 8-h fasting blood samples were obtained in the morning. In the PH and the LVF group, functional class (WHO criteria), metres covered in the 6MWT and echocardiographic parameters were analysed. In the PH group, plasma N terminal pro B type natriuretic peptide (NT-proBNP) level was analysed and a complete haemodynamic evaluation by right heart catheterisation was made.
    Results: Mean Vit D levels were lower in PH than in both other groups (ng/ml, mean ± SD): PH 19.25 ± 10, LVF 25.68 ± 12, HS 28.8 ± 12 (PH vs LVF p = 0.017, PH vs HS p = 0.001 and HS vs LVF p = 0.46). Vit D deficiency prevalence was higher in PH as compared to the other groups (PH 53.8%, LVF 45.2%, HS 25%, p = 0.01). Patients with PH in functional class (FC; WHO criteria) III-IV had higher Vit D deficiency prevalence than those in FC I-II (86.7% vs 40.5%, p = 0.003). There was a significant linear correlation between the 6MWT and Vit D levels in PH (p < 0.01), but not in LVF (p = 0.69).
    Conclusions: Vit D levels were lower in patients with PH as compared to patients with LVF and HS and correlated directly with 6-min walk distance.
    MeSH term(s) Adult ; Aged ; Case-Control Studies ; Cross-Sectional Studies ; Echocardiography ; Female ; Heart Failure/epidemiology ; Humans ; Hypertension, Pulmonary/blood ; Hypertension, Pulmonary/epidemiology ; Hypertension, Pulmonary/physiopathology ; Male ; Middle Aged ; Natriuretic Peptide, Brain/blood ; Peptide Fragments/blood ; Prevalence ; Prognosis ; Ventricular Dysfunction, Left/epidemiology ; Vitamin D/analogs & derivatives ; Vitamin D/blood ; Vitamin D Deficiency/blood ; Vitamin D Deficiency/epidemiology ; Walk Test ; Young Adult
    Chemical Substances Peptide Fragments ; pro-brain natriuretic peptide (1-76) ; Natriuretic Peptide, Brain (114471-18-0) ; Vitamin D (1406-16-2) ; 25-hydroxyvitamin D (A288AR3C9H)
    Language English
    Publishing date 2019-12-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-019-1011-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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