LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 2048

Search options

  1. Article ; Online: Gouty stones in the spinal canal.

    Liu, Shu-Zhong / Qiu, Yu-Zhi / Liang, An-Nan / Xing, Jin-Yi / Zhou, Xi / Liu, Yong

    QJM : monthly journal of the Association of Physicians

    2024  

    Language English
    Publishing date 2024-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcae073
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.131: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Biophysical cues of in vitro biomaterials-based artificial extracellular matrix guide cancer cell plasticity.

    Tang, Rui-Zhi / Liu, Xi-Qiu

    Materials today. Bio

    2023  Volume 19, Page(s) 100607

    Abstract: Clinical evidence supports a role for the extracellular matrix (ECM) in cancer plasticity across multiple tumor types. The lack of in vitro models that represent the native ECMs is a significant challenge for cancer research and drug discovery. Therefore, ...

    Abstract Clinical evidence supports a role for the extracellular matrix (ECM) in cancer plasticity across multiple tumor types. The lack of in vitro models that represent the native ECMs is a significant challenge for cancer research and drug discovery. Therefore, a major motivation for developing new tumor models is to create the artificial ECM in vitro. Engineered biomaterials can closely mimic the architectural and mechanical properties of ECM to investigate their specific effects on cancer progression, offering an alternative to animal models for the testing of cancer cell behaviors. In this review, we focused on the biomaterials from different sources applied in the fabrication of the artificial ECM and their biophysical cues to recapitulate key features of tumor niche. Furthermore, we summarized how the distinct biophysical cues guided cell behaviors of cancer plasticity, including morphology, epithelial-to-mesenchymal transition (EMT), enrichment of cancer stem cells (CSCs), proliferation, migration/invasion and drug resistance. We also discuss the future opportunities in using the artificial ECM for applications of tumorigenesis research and precision medicine, as well as provide useful messages of principles for designing suitable biomaterial scaffolds.
    Language English
    Publishing date 2023-03-08
    Publishing country England
    Document type Journal Article
    ISSN 2590-0064
    ISSN (online) 2590-0064
    DOI 10.1016/j.mtbio.2023.100607
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: A Data Augmentation Method for Motor Imagery EEG Signals Based on DCGAN-GP Network.

    Du, Xiuli / Ding, Xiaohui / Xi, Meiling / Lv, Yana / Qiu, Shaoming / Liu, Qingli

    Brain sciences

    2024  Volume 14, Issue 4

    Abstract: Motor imagery electroencephalography (EEG) signals have garnered attention in brain-computer interface (BCI) research due to their potential in promoting motor rehabilitation and control. However, the limited availability of labeled data poses challenges ...

    Abstract Motor imagery electroencephalography (EEG) signals have garnered attention in brain-computer interface (BCI) research due to their potential in promoting motor rehabilitation and control. However, the limited availability of labeled data poses challenges for training robust classifiers. In this study, we propose a novel data augmentation method utilizing an improved Deep Convolutional Generative Adversarial Network with Gradient Penalty (DCGAN-GP) to address this issue. We transformed raw EEG signals into two-dimensional time-frequency maps and employed a DCGAN-GP network to generate synthetic time-frequency representations resembling real data. Validation experiments were conducted on the BCI IV 2b dataset, comparing the performance of classifiers trained with augmented and unaugmented data. Results demonstrated that classifiers trained with synthetic data exhibit enhanced robustness across multiple subjects and achieve higher classification accuracy. Our findings highlight the effectiveness of utilizing a DCGAN-GP-generated synthetic EEG data to improve classifier performance in distinguishing different motor imagery tasks. Thus, the proposed data augmentation method based on a DCGAN-GP offers a promising avenue for enhancing BCI system performance, overcoming data scarcity challenges, and bolstering classifier robustness, thereby providing substantial support for the broader adoption of BCI technology in real-world applications.
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci14040375
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: β-Galactosidase-Activated and Red Light-Induced RNA Modification Strategy for Prolonged NIR Fluorescence/PET Bimodality Imaging.

    Fang, Jing / Liu, Qingzhu / Liu, Yaling / Li, Ke / Qiu, Ling / Xi, Hongjie / Cai, Shuyue / Zou, Pei / Lin, Jianguo

    Analytical chemistry

    2024  Volume 96, Issue 4, Page(s) 1707–1716

    Abstract: Improving the retention of small-molecule-based therapeutic agents in tumors is crucial to achieve precise diagnosis and effective therapy of cancer. Herein, we propose a β-galactosidase (β-Gal)-activated and red light-induced RNA modification (GALIRM) ... ...

    Abstract Improving the retention of small-molecule-based therapeutic agents in tumors is crucial to achieve precise diagnosis and effective therapy of cancer. Herein, we propose a β-galactosidase (β-Gal)-activated and red light-induced RNA modification (GALIRM) strategy for prolonged tumor imaging. A β-Gal-activatable near-infrared (NIR) fluorescence (FL) and positron emission tomography (PET) bimodal probe
    MeSH term(s) Female ; Humans ; Fluorescence ; Red Light ; Gallium Radioisotopes ; Positron-Emission Tomography/methods ; Ovarian Neoplasms ; beta-Galactosidase ; Furans
    Chemical Substances Gallium Radioisotopes ; beta-Galactosidase (EC 3.2.1.23) ; Furans
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c04845
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4033: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Membrane-Bound Transcription Factor ZmNAC074 Positively Regulates Abiotic Stress Tolerance in Transgenic

    Qian, Yexiong / Xi, Yan / Xia, Lingxue / Qiu, Ziling / Liu, Li / Ma, Hui

    International journal of molecular sciences

    2023  Volume 24, Issue 22

    Abstract: Maize ( ...

    Abstract Maize (
    MeSH term(s) Humans ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Arabidopsis/metabolism ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Plants, Genetically Modified/metabolism ; Gene Expression Regulation, Plant ; Stress, Physiological/genetics ; Zea mays/genetics ; Droughts
    Chemical Substances Transcription Factors ; Plant Proteins
    Language English
    Publishing date 2023-11-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242216157
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Dual-energy CT quantitative parameters to evaluate occult peritoneal metastasis in advanced gastric cancer preoperatively.

    Feng, Qiu-Xia / Zhu, Zhen-Ning / Li, Qiong / Liu, Xi-Sheng

    Abdominal radiology (New York)

    2024  

    Abstract: Purpose: To explore whether dual-energy CT (DECT) quantitative parameters could provide analytic value for the diagnosis of patients with occult peritoneal metastasis (OPM) in advanced gastric cancer preoperatively.: Materials and methods: This ... ...

    Abstract Purpose: To explore whether dual-energy CT (DECT) quantitative parameters could provide analytic value for the diagnosis of patients with occult peritoneal metastasis (OPM) in advanced gastric cancer preoperatively.
    Materials and methods: This retrospective study included 219 patients with advanced gastric cancer and DECT scans. The patient's clinical data and DECT related iodine concentration (IC) parameters and effective atomic number (Z
    Results: Borrmann IV type diagnosed on CT and serum tumor indicator CA125 index were statistically different between the NPM and OPM groups. DECT parameters included IC, normalized IC (NIC), and Z
    Conclusion: The lower quantitative NIC, IC ratio, and Z
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-024-04303-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1262: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: ESRRG, ATP4A, and ATP4B as Diagnostic Biomarkers for Gastric Cancer: A Bioinformatic Analysis Based on Machine Learning.

    Chen, Qiu / Wang, Yu / Liu, Yongjun / Xi, Bin

    Frontiers in physiology

    2022  Volume 13, Page(s) 905523

    Abstract: Based on multiple bioinformatics methods and machine learning techniques, this study was designed to explore potential hub genes of gastric cancer with a diagnostic value. The novel biomarkers were detected through multiple databases of gastric cancer- ... ...

    Abstract Based on multiple bioinformatics methods and machine learning techniques, this study was designed to explore potential hub genes of gastric cancer with a diagnostic value. The novel biomarkers were detected through multiple databases of gastric cancer-related genes. The NCBI Gene Expression Omnibus (GEO) database was used to obtain gene expression files. Three hub genes (
    Language English
    Publishing date 2022-06-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2022.905523
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Facile Construction of 2D/2D ZnIn

    Chen, Yue / Zhu, Liezhen / Shen, Youliang / Liu, Jing / Xi, Jiangbo / Qiu, Lingfang / Xu, Xun / Men, Dandan / Li, Ping / Duo, Shuwang

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 16

    Abstract: A two-dimensional/two-dimensional (2D/2D) ... ...

    Abstract A two-dimensional/two-dimensional (2D/2D) TiO
    Language English
    Publishing date 2023-08-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13162315
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Comparison of Performances among Four Bleeding-Prediction Scores in Elderly Cancer Patients with Venous Thromboembolism.

    Xi, Shaozhi / Liu, Chaoyang / Yu, Shuihua / Qiu, Jingxuan / He, Shuibo / Yi, Zhong

    Hamostaseologie

    2023  Volume 43, Issue 4, Page(s) 281–288

    Abstract: The performances of RIETE, VTE-BLEED, SWITCO65 + , and Hokusai-VTE scores for predicting major bleeding events in hospitalized elderly cancer patients with venous thromboembolism (VTE) have not been evaluated. This study validated the performances of ... ...

    Abstract The performances of RIETE, VTE-BLEED, SWITCO65 + , and Hokusai-VTE scores for predicting major bleeding events in hospitalized elderly cancer patients with venous thromboembolism (VTE) have not been evaluated. This study validated the performances of these scoring systems in a cohort of elderly cancer patients with VTE. Between June 2015 and March 2021, a total of 408 cancer patients (aged ≥ 65 years) with acute VTE were consecutively enrolled. The overall rates of in-hospital major bleeding and clinically relevant bleeding (CRB) were 8.3% (34/408) and 11.8% (48/408), respectively. RIETE score could categorize patients with increasing rate of major bleeding and CRB into low-/intermediate- and high-risk categories (7.1 vs. 14.1%,
    MeSH term(s) Aged ; Humans ; Venous Thromboembolism/complications ; Venous Thromboembolism/diagnosis ; Hemorrhage/diagnosis ; Hemorrhage/etiology ; Neoplasms/complications ; Predictive Value of Tests ; Anticoagulants ; Risk Factors
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2023-05-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 801512-0
    ISSN 2567-5761 ; 0720-9355
    ISSN (online) 2567-5761
    ISSN 0720-9355
    DOI 10.1055/a-1984-7210
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1631: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Poly-L-lactic acid/gelatin electrospun membrane-loaded bone marrow-derived mesenchymal stem cells attenuate erectile dysfunction caused by cavernous nerve injury.

    Hu, Daoyuan / Liu, Chang / Ge, Yunlong / Ye, Lei / Guo, Qiang / Xi, Yuhang / Zhu, Wenliang / Wang, Dejuan / Xu, Tao / Qiu, Jianguang

    International journal of biological macromolecules

    2024  Volume 265, Issue Pt 2, Page(s) 131099

    Abstract: Radical prostatectomy (RP) can cause neurogenic erectile dysfunction (ED), which negatively affects the quality of life of patients with prostate cancer. Currently, there is a dearth of effective therapeutic strategies. Although stem cell therapy is ... ...

    Abstract Radical prostatectomy (RP) can cause neurogenic erectile dysfunction (ED), which negatively affects the quality of life of patients with prostate cancer. Currently, there is a dearth of effective therapeutic strategies. Although stem cell therapy is promising, direct cell transplantation to injured cavernous nerves is constrained by poor cell colonization. In this study, poly-L-lactic acid (PLLA)/gelatin electrospun membranes (PGEM) were fabricated to load bone marrow-derived mesenchymal stem cells (BM-MSCs) as a patch to be placed on injured nerves to alleviate ED. This study aimed to establish a promising and innovative approach to mitigate neurogenic ED post-RP and lay the foundation for modifying surgical procedures. Electrospinning and molecular biotechnology were performed in vitro and in vivo, respectively. It was observed that PGEM enhanced the performance of BM-MSCs and Schwann cells due to their excellent mechanical properties and biocompatibility. The transplanted PGEM and loaded BM-MSCs synergistically improved bilateral cavernous nerve injury-related ED and the corresponding histopathological changes. Nevertheless, transplantation of BM-MSCs alone has been verified to be ineffective. Overall, PGEM can serve as an ideal carrier to supply a more suitable survival environment for BM-MSCs and Schwann cells, thereby promoting the recovery of injured cavernous nerves and erectile function.
    MeSH term(s) Male ; Rats ; Animals ; Humans ; Erectile Dysfunction/etiology ; Erectile Dysfunction/therapy ; Gelatin/metabolism ; Penis/innervation ; Penis/pathology ; Bone Marrow/pathology ; Quality of Life ; Rats, Sprague-Dawley ; Disease Models, Animal ; Mesenchymal Stem Cells/metabolism ; Polyesters
    Chemical Substances poly(lactide) (459TN2L5F5) ; Gelatin (9000-70-8) ; Polyesters
    Language English
    Publishing date 2024-03-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.131099
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2374: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top