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Book ; Online: "How Robust r u?"

Kim, Seokhwan / Liu, Yang / Jin, Di / Papangelis, Alexandros / Gopalakrishnan, Karthik / Hedayatnia, Behnam / Hakkani-Tur, Dilek

Evaluating Task-Oriented Dialogue Systems on Spoken Conversations

2021

Abstract: Most prior work in dialogue modeling has been on written conversations mostly because of existing data sets. However, written dialogues are not sufficient to fully capture the nature of spoken conversations as well as the potential speech recognition ... ...

Abstract	Most prior work in dialogue modeling has been on written conversations mostly because of existing data sets. However, written dialogues are not sufficient to fully capture the nature of spoken conversations as well as the potential speech recognition errors in practical spoken dialogue systems. This work presents a new benchmark on spoken task-oriented conversations, which is intended to study multi-domain dialogue state tracking and knowledge-grounded dialogue modeling. We report that the existing state-of-the-art models trained on written conversations are not performing well on our spoken data, as expected. Furthermore, we observe improvements in task performances when leveraging n-best speech recognition hypotheses such as by combining predictions based on individual hypotheses. Our data set enables speech-based benchmarking of task-oriented dialogue systems. Comment: To be presented at ASRU 2021
Keywords	Computer Science - Computation and Language
Publishing date	2021-09-28
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Systematic study on the effect of seaweed fertilizer on the growth and yield of Vigna radiata (L.) R. Wilczek (Mung bean)

Karthik T. / Jayasri M.A.

Journal of Agriculture and Food Research, Vol 14, Iss , Pp 100748- (2023)

2023

Abstract: ... for biostimulant potential by performing a pot culture on Vigna radiata (L.) R. Wilczek, along with aqueous control ...

Abstract	Seaweed (Marine algae) extracts have been reported to be beneficial to plants for early seed germination, better plant growth, improved crop yield, and also in preventing biotic and abiotic stress. They are naturally rich in plant growth-promoting factors like microelements, organic matter, vitamins, and fatty acids and can be a low-cost alternative to conventional N:P:K fertilizers and expensive organic farming techniques. Herein, the seaweed fertilizer (SF) have prepared by using three seaweeds, viz., Turbinaria ornata (TSF), Ulva intestinalis (USF), and Portieria hornemannii (PSF). The formulation was evaluated for biostimulant potential by performing a pot culture on Vigna radiata (L.) R. Wilczek, along with aqueous control, chemical fertilizer control (CFC), and organic manure control (OMC). The plants were treated with various groupings (individual and combination) of SF at six different concentrations. The study revealed that PSF (30%) stimulates maximum seed germination and an upsurge in plant growth (shoot length (28%), root length (120%), leaf count (53%), leaf area (62%), fresh weight (41%), and dry weight (54%)), pigment concentration (carotenoid (80%), chlorophyll a (29%), and chlorophyll b (41%)), and biochemical parameters of the leaves (carbohydrate (18%), protein (21%), amino acids (21%), phenolic content(49%)) when compared with aqueous control. The study revealed an 85% surge in the quantity of grains (15.568 g/plant) upon treatment with 30% PSF compared with aqueous control (8.413 g/plant). Followed by 30% (USF + PSF), 30% (TSF + PSF), and 40% PSF, have exhibited 75%, 73%, and 72% increase, respectively, compared with aqueous control. The nutrient uptake study exhibited that 30% PSF improves the efficiency of mineral uptake in V. radiata (L) plants. The results suggest that the tested SF, especially PSF, could be a low-cost and environmentally safe fertilizer. Based on this study, the formulated PSF could be used alone or partially replaced with commercial fertilizers to reduce the total ...
Keywords	Vigna radiata (L.) R. Wilczek ; Macro algae ; Organic fertilizer ; Plant growth promoter ; Yield efficiency ; Nutrient uptake efficiency ; Agriculture (General) ; S1-972 ; Nutrition. Foods and food supply ; TX341-641
Subject code	580
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Cytogenetics and Revised International Staging System (R-ISS): Risk Stratification in Multiple myeloma - A Retrospective Study in Indian Population.

Udupa, Chethana Babu K / Udupa, Karthik Subramanaya / Pai, Ananth / Sherigar, Prathika

Iranian journal of pathology

2020 Volume 15, Issue 3, Page(s) 182–188

Abstract: ... stratification by Revised International Staging System (R-ISS) among Indian population.: Methods: A single ... were staged according to Revised International Staging System (R- ISS).: Results: Out of the 117 ... patients, 37 (31.62%) were staged R-ISS III.: Conclusion: High risk cytogenetics was found in 16.23 ...

Abstract	Background & objective: Cytogenetic abnormalities in Multiple myeloma (MM) has emerged as the most important factor that determine the prognosis and survival. Fluorescence in situ hybridization (FISH) can detect a greater number of cytogenetic abnormalities as compared to conventional karyotyping and hence has become the standard test in determining genetic abnormalities in MM. The present study was planned as there is an unmet need to find out various cytogenetic abnormalities and to implement them in prognostic stratification by Revised International Staging System (R-ISS) among Indian population. Methods: A single institution retrospective study was conducted among a total of 117 patients newly diagnosed as Multiple Myeloma. They were analyzed for various cytogenetic abnormalities by using interphase FISH (iFISH) and were staged according to Revised International Staging System (R- ISS). Results: Out of the 117 patients studied, deletion 17p13 (p53) was present in 16 patients (13.67%). Thirty patients (25.64%) showed deletion 13q14.3. Three patients (2.56%) were detected to have t(4:14).Two patients (1.7%) had t(11:14) and t(14:16), respectively. Total of 19 patients (16.23%) in our study exhibited high risk cytogenetics and two among them had more than one high risk cytogenetic abnormalities. There was a 66.4% moderate correlation between ISS-III and high-risk cytogenetics which was statistically insignificant. Of the total 117 patients, 37 (31.62%) were staged R-ISS III. Conclusion: High risk cytogenetics was found in 16.23 % of our study population and del 17p13 was the most common high-risk cytogenetic abnormality. Of the studied subjects, 31.62% had R-ISS III, which is significantly higher compared to western population.
Language	English
Publishing date	2020-04-21
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2478278-6
ISSN	1735-5303 ; 2345-3656
ISSN	1735-5303 ; 2345-3656
DOI	10.30699/ijp.2020.105128.2078
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Intratumoral T-cell receptor repertoire is predictive of interim PET scan results in patients with diffuse large B-cell lymphoma treated with rituximab/cyclophosphamide/doxorubicin/prednisolone/vincristine (R-CHOP) chemoimmunotherapy.

Shanavas, Mohamed / Law, Soi-Cheng / Hertzberg, Mark / Hicks, Rodney J / Seymour, John F / Li, Zhixiu / Merida de Long, Lilia / Nath, Karthik / Sabdia, Muhammed B / Gunawardana, Jay / Gandhi, Maher K / Keane, Colm

Clinical & translational immunology

2021 Volume 10, Issue 11, Page(s) e1351

Abstract: ... prednisolone/vincristine (R-CHOP) chemoimmunotherapy. We explored the impact of intratumoral TCR repertoire ... on interim PET (iPET) done after four cycles of R-CHOP, the relationships between intratumoral and ... the third complementarity-determining region of TCRβ in tumor samples, blood at pre-therapy and after four cycles of R-CHOP in 35 patients ...

Abstract	Objectives: A diverse intratumoral T-cell receptor (TCR) repertoire is associated with improved survival in diffuse large B-cell lymphoma (DLBCL) treated with rituximab/cyclophosphamide/doxorubicin/prednisolone/vincristine (R-CHOP) chemoimmunotherapy. We explored the impact of intratumoral TCR repertoire on interim PET (iPET) done after four cycles of R-CHOP, the relationships between intratumoral and circulating repertoire, and the phenotypes of expanded clonotypes. Methods: We sequenced the third complementarity-determining region of TCRβ in tumor samples, blood at pre-therapy and after four cycles of R-CHOP in 35 patients enrolled in ALLGNHL21 trial in high-risk DLBCL. We correlated the TCR diversity metrics with iPET status, gene expression profiles and HLA-class I genotypes. We then sequenced the FACS-sorted peripheral blood T cells in six patients, and pentamer-sorted EBV-specific CD8 Results: Compared with iPET Conclusion: This study demonstrates that clonally expanded intratumoral TCR repertoires are associated with iPET
Language	English
Publishing date	2021-10-27
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2694482-0
ISSN	2050-0068
ISSN	2050-0068
DOI	10.1002/cti2.1351
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Article ; Online: Path R-CNN for Prostate Cancer Diagnosis and Gleason Grading of Histological Images.

Li, Wenyuan / Li, Jiayun / Sarma, Karthik V / Ho, King Chung / Shen, Shiwen / Knudsen, Beatrice S / Gertych, Arkadiusz / Arnold, Corey W

IEEE transactions on medical imaging

2018 Volume 38, Issue 4, Page(s) 945–954

Abstract: Prostate cancer is the most common and second most deadly form of cancer in men in the United States. The classification of prostate cancers based on Gleason grading using histological images is important in risk assessment and treatment planning for ... ...

Abstract	Prostate cancer is the most common and second most deadly form of cancer in men in the United States. The classification of prostate cancers based on Gleason grading using histological images is important in risk assessment and treatment planning for patients. Here, we demonstrate a new region-based convolutional neural network framework for multi-task prediction using an epithelial network head and a grading network head. Compared with a single-task model, our multi-task model can provide complementary contextual information, which contributes to better performance. Our model is achieved a state-of-the-art performance in epithelial cells detection and Gleason grading tasks simultaneously. Using fivefold cross-validation, our model is achieved an epithelial cells detection accuracy of 99.07% with an average area under the curve of 0.998. As for Gleason grading, our model is obtained a mean intersection over union of 79.56% and an overall pixel accuracy of 89.40%.
MeSH term(s)	Histocytochemistry ; Humans ; Image Interpretation, Computer-Assisted/methods ; Male ; Neoplasm Grading/methods ; Neural Networks, Computer ; Prostate/diagnostic imaging ; Prostatic Neoplasms/diagnostic imaging
Language	English
Publishing date	2018-10-12
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	622531-7
ISSN	1558-254X ; 0278-0062
ISSN (online)	1558-254X
ISSN	0278-0062
DOI	10.1109/TMI.2018.2875868
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Article ; Online: Biodegradation of Remazol Brilliant Blue R using isolated bacterial culture (Staphylococcus sp. K2204).

Velayutham, Karthikeyan / Madhava, Anil Kumar / Pushparaj, Mohanapriya / Thanarasu, Amudha / Devaraj, Thiruselvi / Periyasamy, Karthik / Subramanian, Sivanesan

Environmental technology

2017 Volume 39, Issue 22, Page(s) 2900–2907

Abstract: ... Brilliant Blue R (RBBR), which belongs to the anthraquinone class of textile dye. Staphylococcus sp. K2204 ...

Abstract	Staphylococcus sp. K2204, a bacterial isolate, was employed in this work to decolorize Remazol Brilliant Blue R (RBBR), which belongs to the anthraquinone class of textile dye. Staphylococcus sp. K2204 biodegraded 100 mg/L RBBR at 37°C under static condition with the help of extracellular laccase and peroxidases. The products of RBBR degradation were characterized using analytical tools including mass spectral technique. The phytotoxicity tests evaluated the toxicity of RBBR and the products of biodegradation. The research outlined here is the first attempt to utilize Staphylococcus sp. K2204 for remediating the wastewater containing anthraquinone textile dye.
MeSH term(s)	Anthraquinones ; Biodegradation, Environmental ; Color ; Coloring Agents ; Laccase ; Staphylococcus
Chemical Substances	Anthraquinones ; Coloring Agents ; Laccase (EC 1.10.3.2) ; Remazol Brilliant Blue R (L51IMM9UP9)
Language	English
Publishing date	2017-09-03
Publishing country	England
Document type	Journal Article
ISSN	1479-487X
ISSN (online)	1479-487X
DOI	10.1080/09593330.2017.1369579
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Article: Biodegradation of Remazol Brilliant Blue R using isolated bacterial culture (Staphylococcus sp. K2204)

Velayutham, Karthikeyan / Amudha Thanarasu / Anil Kumar Madhava / Karthik Periyasamy / Mohanapriya Pushparaj / Sivanesan Subramanian / Thiruselvi Devaraj

Environmental technology. 2018 Nov. 17, v. 39, no. 22

2018

Abstract: ... Brilliant Blue R (RBBR), which belongs to the anthraquinone class of textile dye. Staphylococcus sp. K2204 ...

Abstract	Staphylococcus sp. K2204, a bacterial isolate, was employed in this work to decolorize Remazol Brilliant Blue R (RBBR), which belongs to the anthraquinone class of textile dye. Staphylococcus sp. K2204 biodegraded 100 mg/L RBBR at 37°C under static condition with the help of extracellular laccase and peroxidases. The products of RBBR degradation were characterized using analytical tools including mass spectral technique. The phytotoxicity tests evaluated the toxicity of RBBR and the products of biodegradation. The research outlined here is the first attempt to utilize Staphylococcus sp. K2204 for remediating the wastewater containing anthraquinone textile dye.
Keywords	anthraquinones ; bacterial culture ; biodegradation ; dyes ; environmental technology ; fabrics ; laccase ; peroxidases ; phytotoxicity ; Staphylococcus ; wastewater
Language	English
Dates of publication	2018-1117
Size	p. 2900-2907.
Publishing place	Taylor & Francis
Document type	Article
ISSN	1479-487X
DOI	10.1080/09593330.2017.1369579
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Crystal structure, Hirshfeld surface analysis and DFT studies of 1-[r-2,c-6-diphenyl-t-3-(propan-2-yl)piperidin-1-yl]ethan-1-one

P. Periyannan / M. Beemarao / K. Karthik / S. Ponnuswamy / K. Ravichandran

Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 3, Pp 377-

2020 Volume 381

Abstract: In the title compound, C22H27NO, the piperidine ring adopts a chair conformation. The dihedral angles between the mean plane of the piperidine ring and the phenyl rings are 89.78 (7) and 48.30 (8)°. In the crystal, molecules are linked into chains along ... ...

Abstract	In the title compound, C22H27NO, the piperidine ring adopts a chair conformation. The dihedral angles between the mean plane of the piperidine ring and the phenyl rings are 89.78 (7) and 48.30 (8)°. In the crystal, molecules are linked into chains along the b-axis direction by C—H.O hydrogen bonds. The DFT/B3LYP/6–311 G(d,p) method was used to determine the HOMO–LUMO energy levels. The molecular electrostatic potential surfaces were investigated by Hirshfeld surface analysis and two-dimensional fingerprint plots were used to analyse the intermolecular interactions in the molecule.
Keywords	crystal structure ; piperidine derivative ; hirshfeld surface ; dft ; Chemistry ; QD1-999
Language	English
Publishing date	2020-03-01T00:00:00Z
Publisher	International Union of Crystallography
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Quantitative fractography of mixed-mode fracture in an R-curve material

Gopalakrishnan, Karthik / Mecholsky, John J., Jr

Journal of materials science. 2013 Oct., v. 48, no. 20

2013

Abstract: Mixed-mode fracture surfaces of an R-curve material were quantitatively assessed using fractography ... The R-curve material chosen was a mica glass ceramic. Vickers indentation cracks of different sizes were ...

Abstract	Mixed-mode fracture surfaces of an R-curve material were quantitatively assessed using fractography. The R-curve material chosen was a mica glass ceramic. Vickers indentation cracks of different sizes were introduced at the center of tensile surface of glass ceramic bars fractured in flexure. The bars were fractured in flexure by generating mixed-mode (I/II) loading conditions at crack tips by orienting indentation cracks at various angles with respect to the tensile axis. Quantitative fractography indicated that crack-to-mirror size ratios were a function of crack length and mode mixity. Stress intensity at branching for the mirror–hackle transition during mixed-mode (I/II) fracture condition was a constant and was less than the corresponding stress intensity at branching in mode I loading. An empirical relationship is derived for the effective geometric factors in mixed-mode fracture of ceramics from surface cracks in flexure.
Keywords	ceramics ; glass ; mica ; tensile strength
Language	English
Dates of publication	2013-10
Size	p. 7081-7087.
Publishing place	Springer-Verlag
Document type	Article
ZDB-ID	2015305-3
ISSN	1573-4803 ; 0022-2461
ISSN (online)	1573-4803
ISSN	0022-2461
DOI	10.1007/s10853-013-7520-5
Database	NAL-Catalogue (AGRICOLA)

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Article: "Not everyone deserves the Green Channel": Self-declaration in the publication is only for the truly mature and honest.

Karthik, Raghavendhar

Journal of oral and maxillofacial pathology : JOMFP

2023 Volume 27, Issue 1, Page(s) 18–19

Language	English
Publishing date	2023-03-21
Publishing country	India
Document type	Journal Article
ZDB-ID	2390999-7
ISSN	1998-393X ; 0973-029X
ISSN (online)	1998-393X
ISSN	0973-029X
DOI	10.4103/jomfp.jomfp_77_23
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