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  1. Article ; Online: Corrigendum to "Medically unexplained visual loss in a specialist clinic: A retrospective case-control comparison", [Journal of the Neurological Sciences 361 (2016) 272-276].

    O'Leary, Éanna D / McNeillis, Benjamin / Aybek, Selma / Riordan-Eva, Paul / David, Anthony S

    Journal of the neurological sciences

    2021  Volume 429, Page(s) 117609

    Language English
    Publishing date 2021-08-04
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2021.117609
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  2. Article ; Online: Sigmoid Sinus Diverticulum, Dehiscence, and Venous Sinus Stenosis: Potential Causes of Pulsatile Tinnitus in Patients with Idiopathic Intracranial Hypertension?

    Lansley, J A / Tucker, W / Eriksen, M R / Riordan-Eva, P / Connor, S E J

    AJNR. American journal of neuroradiology

    2017  Volume 38, Issue 9, Page(s) 1783–1788

    Abstract: Background and purpose: Pulsatile tinnitus is experienced by most patients with idiopathic intracranial hypertension. The pathophysiology remains uncertain; however, transverse sinus stenosis and sigmoid sinus diverticulum/dehiscence have been proposed ... ...

    Abstract Background and purpose: Pulsatile tinnitus is experienced by most patients with idiopathic intracranial hypertension. The pathophysiology remains uncertain; however, transverse sinus stenosis and sigmoid sinus diverticulum/dehiscence have been proposed as potential etiologies. We aimed to determine whether the prevalence of transverse sinus stenosis and sigmoid sinus diverticulum/dehiscence was increased in patients with idiopathic intracranial hypertension and pulsatile tinnitus relative to those without pulsatile tinnitus and a control group.
    Materials and methods: CT vascular studies of patients with idiopathic intracranial hypertension with pulsatile tinnitus (
    Results: Severe bilateral transverse sinus stenoses were more frequent in patients with idiopathic intracranial hypertension than in controls (
    Conclusions: While our data corroborate previous studies demonstrating increased prevalence of sigmoid sinus diverticulum/dehiscence and transverse sinus stenosis in idiopathic intracranial hypertension, we did not establish an increased prevalence in patients with idiopathic intracranial hypertension with pulsatile tinnitus compared with those without. It is therefore unlikely that these entities represent a direct structural correlate of pulsatile tinnitus in patients with idiopathic intracranial hypertension.
    MeSH term(s) Aged ; Constriction, Pathologic/complications ; Constriction, Pathologic/epidemiology ; Cranial Sinuses/pathology ; Female ; Humans ; Male ; Middle Aged ; Pseudotumor Cerebri/complications ; Pseudotumor Cerebri/pathology ; Tinnitus/etiology
    Language English
    Publishing date 2017-07-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A5277
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  3. Article: Clinical assessment of optic nerve disorders.

    Riordan-Eva, P

    Eye (London, England)

    2004  Volume 18, Issue 11, Page(s) 1161–1168

    Abstract: Optic nerve disorders range from the manifestations of life-threatening intracranial or systemic disease, to minor congenital anomalies. Careful clinical assessment, which relies upon a thorough evaluation of symptoms as well as signs, is essential for ... ...

    Abstract Optic nerve disorders range from the manifestations of life-threatening intracranial or systemic disease, to minor congenital anomalies. Careful clinical assessment, which relies upon a thorough evaluation of symptoms as well as signs, is essential for effective and timely investigation and treatment. Examination methods and pitfalls to be avoided are discussed.
    MeSH term(s) Color Perception/physiology ; Humans ; Optic Disk/physiology ; Optic Nerve Diseases/complications ; Optic Nerve Diseases/diagnosis ; Optic Nerve Diseases/physiopathology ; Pupil/physiology ; Vision Disorders/etiology ; Vision Tests/methods ; Visual Acuity/physiology ; Visual Fields/physiology
    Language English
    Publishing date 2004-11
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/sj.eye.6701575
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  4. Article: Abnormal optic discs and renal failure: papillorenal syndrome.

    Nguyen, Dan / Riordan-Eva, Paul

    Acta ophthalmologica Scandinavica

    2006  Volume 84, Issue 6, Page(s) 823–824

    MeSH term(s) Abnormalities, Multiple/diagnosis ; Abnormalities, Multiple/genetics ; Adult ; Coloboma/diagnosis ; Female ; Humans ; Hypertension/diagnosis ; Kidney/abnormalities ; Kidney Failure, Chronic/diagnosis ; Optic Disk/abnormalities ; Optic Disk/blood supply ; Syndrome
    Language English
    Publishing date 2006-12
    Publishing country Denmark
    Document type Case Reports ; Journal Article
    ZDB-ID 1230907-2
    ISSN 1600-0420 ; 1395-3907
    ISSN (online) 1600-0420
    ISSN 1395-3907
    DOI 10.1111/j.1600-0420.2006.00688.x
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  5. Article: Neuro-ophthalmology of mitochondrial diseases.

    Riordan-Eva, P

    Current opinion in ophthalmology

    2000  Volume 11, Issue 6, Page(s) 408–412

    Abstract: Polymorphism in mitochondrial DNA necessitates careful scrutiny of potentially pathogenic mutations to establish their true pathogenic significance. Research on Leber hereditary optic neuropathy continues to provide insights into the pathogenesis of ... ...

    Abstract Polymorphism in mitochondrial DNA necessitates careful scrutiny of potentially pathogenic mutations to establish their true pathogenic significance. Research on Leber hereditary optic neuropathy continues to provide insights into the pathogenesis of mitochondrial disease. Interest in the retinal manifestations of mitochondrial disease has highlighted the macular dystrophy of the 3243 mutation, particularly in association with the syndrome of maternally inherited diabetes and deafness. Mitochondrial encephalopathies present in a number of ways, but imaging predominantly shows abnormalities of myelin and grey-matter nuclei. The mitochondrial myopathies provide insights into interactions between nuclear and mitochondrial DNA mutations and parallels between mitochondrial diseases and aging.
    MeSH term(s) Aging/genetics ; DNA, Mitochondrial/analysis ; DNA, Mitochondrial/genetics ; Diagnosis, Differential ; Diagnostic Imaging ; Humans ; Mitochondrial Myopathies/complications ; Mitochondrial Myopathies/diagnosis ; Mitochondrial Myopathies/genetics ; Mutation ; Optic Atrophies, Hereditary/diagnosis ; Optic Atrophies, Hereditary/etiology ; Optic Atrophies, Hereditary/genetics ; Polymorphism, Genetic ; Retinal Diseases/diagnosis ; Retinal Diseases/etiology ; Retinal Diseases/genetics
    Chemical Substances DNA, Mitochondrial
    Language English
    Publishing date 2000-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1049383-9
    ISSN 1531-7021 ; 1040-8738
    ISSN (online) 1531-7021
    ISSN 1040-8738
    DOI 10.1097/00055735-200012000-00005
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  6. Article ; Online: Medically unexplained visual loss in a specialist clinic: a retrospective case-control comparison.

    O'Leary, Éanna D / McNeillis, Benjamin / Aybek, Selma / Riordan-Eva, Paul / David, Anthony S

    Journal of the neurological sciences

    2015  Volume 361, Page(s) 272–276

    Abstract: Purpose: To compare the clinical and demographic characteristics of adult patients with nonorganic or medically unexplained visual loss (MUVL) to those with other common conditions presenting to a neuro-ophthalmology clinic.: Methods: Case-control ... ...

    Abstract Purpose: To compare the clinical and demographic characteristics of adult patients with nonorganic or medically unexplained visual loss (MUVL) to those with other common conditions presenting to a neuro-ophthalmology clinic.
    Methods: Case-control design: a retrospective review of medical notes on a consecutive case series of 49 patients assessed at the King's College Hospital neuro-ophthalmology clinic with unexplained visual loss and matched with the next assessed patient identified from clinic records. Patients presented post-symptom onset with a mean clinical course of 30 months (SD=67 months) and standard clinical examination used to confirm diagnoses, alongside ancillary investigations if required.
    Results: Seventy-two percent (n=36) of MUVL patients were female. In comparison with patients with organic visual disorders, MUVL cases presented with significantly higher rates of bilateral (cf. unilateral) visual impairment (41%, n=20), premorbid psychiatric (27%, n=13) as well as functional (24%, n=12) diagnoses and psychotropic medication usage (22%, n=11). Medically unexplained cases were significantly more likely to report preceding psychological stress (n=9; 18%).
    Conclusions: Medically unexplained visual impairment may be regarded as part of the spectrum of medically unexplained disorders seen in the general hospital setting. Research is needed to determine long-term outcomes and effective tailored interventions.
    MeSH term(s) Adolescent ; Adult ; Case-Control Studies ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Specialization ; Symptom Assessment ; Vision Disorders/diagnosis ; Vision Disorders/etiology ; Young Adult
    Language English
    Publishing date 2015-12-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2015.12.045
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  7. Article ; Online: Subacute peripheral and optic neuropathy syndrome with no evidence of a toxic or nutritional cause.

    Allen, D / Riordan-Eva, P / Paterson, R W / Hadden, R D M

    Clinical neurology and neurosurgery

    2013  Volume 115, Issue 8, Page(s) 1389–1393

    Abstract: Background: The syndrome of subacute simultaneous peripheral neuropathy and bilateral optic neuropathy is known to occur in tropical countries, probably due to malnutrition or toxicity, but not often seen in developed countries. We report seven patients ...

    Abstract Background: The syndrome of subacute simultaneous peripheral neuropathy and bilateral optic neuropathy is known to occur in tropical countries, probably due to malnutrition or toxicity, but not often seen in developed countries. We report seven patients in London who were not malnourished or alcoholic, and in whom no clear cause was found.
    Methods: We retrospectively reviewed the case notes and arranged some further investigations.
    Results: All patients developed peripheral and bilateral optic neuropathy within 6 months. Patients were aged 30-52, and all of Jamaican birth and race but lived in the UK. Most had subacute, painful ataxic sensory axonal neuropathy or neuronopathy, some with myelopathy. Nerve conduction studies revealed minor demyelinating features in two cases. The optic neuropathy was symmetrical, subacute and monophasic, usually with marked reduction in visual acuity. CSF protein concentration was usually elevated but other laboratory investigations were normal. Patients showed only modest improvement at follow-up.
    Conclusion: These patients share a common clinical and electrophysiological phenotype, age, ethnicity and elevated CSF protein, but otherwise normal laboratory investigations. The syndrome is a cause of significant morbidity in young people. The cause remains uncertain despite thorough investigation.
    MeSH term(s) Adult ; Alcoholism/epidemiology ; Anti-Inflammatory Agents/therapeutic use ; Cerebrospinal Fluid Proteins/analysis ; Electromyography ; Electroretinography ; Evoked Potentials, Visual/physiology ; Female ; Humans ; London/epidemiology ; Male ; Middle Aged ; Neural Conduction ; Neurologic Examination ; Nutritional Status ; Optic Nerve Diseases/complications ; Optic Nerve Diseases/drug therapy ; Optic Nerve Diseases/etiology ; Pain/etiology ; Peripheral Nervous System Diseases/complications ; Peripheral Nervous System Diseases/drug therapy ; Peripheral Nervous System Diseases/etiology ; Polyneuropathies/complications ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/complications ; Retrospective Studies ; Steroids/therapeutic use ; Syndrome ; Visual Acuity
    Chemical Substances Anti-Inflammatory Agents ; Cerebrospinal Fluid Proteins ; Steroids
    Language English
    Publishing date 2013-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 193107-6
    ISSN 1872-6968 ; 0303-8467
    ISSN (online) 1872-6968
    ISSN 0303-8467
    DOI 10.1016/j.clineuro.2013.01.002
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  8. Article: Disorders of the anterior visual pathways.

    Madill, S A / Riordan-Eva, P

    Journal of neurology, neurosurgery, and psychiatry

    2004  Volume 75 Suppl 4, Page(s) iv12–19

    MeSH term(s) Diagnosis, Differential ; Diagnostic Techniques, Ophthalmological ; Electrophysiology ; Humans ; Optic Nerve Diseases/diagnosis ; Optic Nerve Diseases/pathology ; Retinal Diseases/diagnosis ; Retinal Diseases/pathology
    Language English
    Publishing date 2004-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp.2004.053421
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  9. Article: Late onset of Leber's hereditary optic neuropathy precipitated by anaemia.

    Goyal, S / Riordan-Eva, P / Coakes, R L

    Eye (London, England)

    2004  Volume 18, Issue 10, Page(s) 1017–1018

    MeSH term(s) Aged ; Anemia/complications ; Humans ; Male ; Optic Atrophy, Hereditary, Leber/etiology ; Scotoma/etiology
    Language English
    Publishing date 2004-10
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/sj.eye.6701388
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  10. Article ; Online: A 67-year-old woman with shaking of the world.

    Turner, Stephen J / Riordan-Eva, Paul / Connor, Steve / Samuel, Michael

    Digital journal of ophthalmology : DJO

    2008  Volume 14, Page(s) 28–29

    Language English
    Publishing date 2008
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2030129-7
    ISSN 1542-8958 ; 1542-8958
    ISSN (online) 1542-8958
    ISSN 1542-8958
    DOI 10.5693/djo.03.2008.009
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