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Article ; Online: Danser la communauté comme une danse populaire. "Bit" de Maguy Marin

Claudia Palazzolo

Danza e Ricerca, Vol 10, Iss 10, Pp 147-

2018 Volume 159

Abstract: Cet article est l’étape d’une recherche concernant le traitement théâtral des pratiques sociales de la danse et les effets de ce traitement du point de vue esthétique et dramaturgique. Le cas ici analysé est la pièce Bit(2014) de la chorégraphe Maguy ... ...

Abstract	Cet article est l’étape d’une recherche concernant le traitement théâtral des pratiques sociales de la danse et les effets de ce traitement du point de vue esthétique et dramaturgique. Le cas ici analysé est la pièce Bit(2014) de la chorégraphe Maguy Marin. En s’appuyant sur l’appareil discursif constitué de déclarations publiques de la chorégraphe et de l’ensemble de textes de réception critique, l’article analysera la manière dans laquelle cette allusion à la danse de société et la relation singulière qu’elle établit avec le spectateur, propose une vision complexe de la communauté dans le monde contemporain.
Keywords	Recreation. Leisure ; GV1-1860 ; Dancing ; GV1580-1799.4
Language	Italian
Publishing date	2018-12-01T00:00:00Z
Publisher	University of Bologna
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Biocontrol of Alternaria alternata in cold-stored table grapes using psychrotrophic yeasts and bioactive compounds of natural sources.

Torres-Palazzolo, Carolina / Ferreyra, Susana / Iribas, Francisco / Chimeno, Valeria / Rojo, Maria Cecilia / Casalongue, Claudia / Fontana, Ariel / Combina, Mariana / Ponsone, Maria Lorena

International journal of food microbiology

2024 Volume 415, Page(s) 110640

Abstract: Alternaria alternata is a common fungal pathogen causing postharvest decay in table grapes. This study addressed the potential of autochthonous yeasts and bioactive compounds of natural sources to act as biocontrol agents (BCAs) against A. alternata in ... ...

Abstract	Alternaria alternata is a common fungal pathogen causing postharvest decay in table grapes. This study addressed the potential of autochthonous yeasts and bioactive compounds of natural sources to act as biocontrol agents (BCAs) against A. alternata in cold-stored table grapes. With this purpose, 19 yeast capable of growing at 0-1 °C were isolated from the surface of Red Globe table grapes. These isolates, along with the pre-isolated strain Metschnikowia pulcherrima RCM2, were evaluated as BCAs in wounded berries. From these results, six yeast isolates were pre-selected to be combined with bioactive compounds of natural sources, like phenolic compounds (PCs) of side streams of wine industry, including bunch stem extract (BSE) (5-25 %), and cane extract (CE) (5-25 %), and functional polysaccharides from shrimp waste such as chitosan (CH) (0.5 %). Then, the biocontrol efficacy of combined treatments beyond individual ones was compared. The results revealed that 4 yeast isolates, namely M. pulcherrima RCM2 and ULA146, and Aureobasidium pullulans FUL14 and FUL18, were the most effective. However, when combined with the natural bioactive compounds, their efficacy against A. alternata did not increase significantly. Notably, ULA146 and FUL18 demonstrated a biocontrol efficacy of 36-37 %, comparable to that of the treatment with commercial doses of SO
MeSH term(s)	Vitis/microbiology ; Yeasts ; Alternaria ; Fungicides, Industrial
Chemical Substances	Fungicides, Industrial
Language	English
Publishing date	2024-02-27
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	87122-9
ISSN	1879-3460 ; 0168-1605
ISSN (online)	1879-3460
ISSN	0168-1605
DOI	10.1016/j.ijfoodmicro.2024.110640
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Article: Efficacy and Safety of Anticoagulant Therapy in COVID-19-Related Pulmonary Embolism with Different Extension.

Gatto, Maria Chiara / Oliva, Alessandra / Palazzolo, Claudia / Picariello, Claudio / Garascia, Andrea / Nicastri, Emanuele / Girardi, Enrico / Antinori, Andrea

Biomedicines

2023 Volume 11, Issue 5

Abstract: Pulmonary embolism (PE) has been associated with SARS-CoV-2 infection, and its incidence is highly variable. The aim of our study was to describe the radiological and clinical presentations, as well as the therapeutic management, of PEs that occurred ... ...

Abstract	Pulmonary embolism (PE) has been associated with SARS-CoV-2 infection, and its incidence is highly variable. The aim of our study was to describe the radiological and clinical presentations, as well as the therapeutic management, of PEs that occurred during SARS-CoV-2 infection in a cohort of hospitalized patients. In this observational study, we enrolled patients with moderate COVID-19 who developed PE during hospitalization. Clinical, laboratory, and radiological features were recorded. PE was diagnosed on clinical suspicion and/or CT angiography. According to CT angiography results, two groups of patients were further distinguished: those with proximal or central pulmonary embolism (cPE) and those with distal or micro-pulmonary embolism (mPE). A total of 56 patients with a mean age of 78 ± 15 years were included. Overall, PE occurred after a median of 2 days from hospitalization (range 0-47 days) and, interestingly, the majority of them (89%) within the first 10 days of hospitalization, without differences between the groups. Patients with cPE were younger (
Language	English
Publishing date	2023-04-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines11051282
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Article ; Online: A machine learning approach for early identification of patients with severe imported malaria.

D'Abramo, Alessandra / Rinaldi, Francesco / Vita, Serena / Mazzieri, Riccardo / Corpolongo, Angela / Palazzolo, Claudia / Ascoli Bartoli, Tommaso / Faraglia, Francesca / Giancola, Maria Letizia / Girardi, Enrico / Nicastri, Emanuele

Malaria journal

2024 Volume 23, Issue 1, Page(s) 46

Abstract: Background: The aim of this study is to design ad hoc malaria learning (ML) approaches to predict clinical outcome in all patients with imported malaria and, therefore, to identify the best clinical setting.: Methods: This is a single-centre cross- ... ...

Abstract	Background: The aim of this study is to design ad hoc malaria learning (ML) approaches to predict clinical outcome in all patients with imported malaria and, therefore, to identify the best clinical setting. Methods: This is a single-centre cross-sectional study, patients with confirmed malaria, consecutively hospitalized to the Lazzaro Spallanzani National Institute for Infectious Diseases, Rome, Italy from January 2007 to December 2020, were recruited. Different ML approaches were used to perform the analysis of this dataset: support vector machines, random forests, feature selection approaches and clustering analysis. Results: A total of 259 patients with malaria were enrolled, 89.5% patients were male with a median age of 39 y/o. In 78.3% cases, Plasmodium falciparum was found. The patients were classified as severe malaria in 111 cases. From ML analyses, four parameters, AST, platelet count, total bilirubin and parasitaemia, are associated to a negative outcome. Interestingly, two of them, aminotransferase and platelet are not included in the current list of World Health Organization (WHO) criteria for defining severe malaria. Conclusion: In conclusion, the application of ML algorithms as a decision support tool could enable the clinicians to predict the clinical outcome of patients with malaria and consequently to optimize and personalize clinical allocation and treatment.
MeSH term(s)	Humans ; Male ; Female ; Cross-Sectional Studies ; Retrospective Studies ; Malaria/diagnosis ; Malaria/drug therapy ; Plasmodium falciparum ; Italy ; Malaria, Falciparum/diagnosis
Language	English
Publishing date	2024-02-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2091229-8
ISSN	1475-2875 ; 1475-2875
ISSN (online)	1475-2875
ISSN	1475-2875
DOI	10.1186/s12936-024-04869-3
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Article: 2-Vinyl-4H-1,3-Dithiin, a Bioavailable Compound from Garlic, Inhibits Vascular Smooth Muscle Cells Proliferation and Migration by Reducing Oxidative Stress

Torres-Palazzolo, Carolina / de Paola, Matilde / Quesada, Isabel / Camargo, Alejandra / Castro, Claudia

Plant foods for human nutrition. 2020 Sept., v. 75, no. 3

2020

Abstract: Organosulfur compounds (OSCs) of garlic have various health benefits including anti-hypertensive effect. It has been described that volatile OSCs uptake occurs into a moderate extent. Among the bioavailable OSCs present in garlic, 2-vinyl-4H-1,3-dithiin ( ...

Abstract	Organosulfur compounds (OSCs) of garlic have various health benefits including anti-hypertensive effect. It has been described that volatile OSCs uptake occurs into a moderate extent. Among the bioavailable OSCs present in garlic, 2-vinyl-4H-1,3-dithiin (2VD) is a main component in garlic macerated oil and stir-fried garlic but has been poorly investigated compared with others OSCs, such allyl mercaptan (AM) and S-allyl cysteine (SAC). The aim of this study was to evaluate the effects of 2VD on vascular smooth muscle cells (VSMCs) isolated from spontaneous hypertensive rats (SHR) and compare them with those produced by AM and SAC. Cell viability and proliferation were measured using tetrazolium dye MTT assay and flow cytometry. Cell migration was evaluated by scrape-wound migration assay. OSCs anti-oxidative capacity was determined by measuring reactive oxygen species (ROS) generation, and total antioxidant status (TAS). Non-toxic plasmatic concentrations (10 μg L⁻¹) of 2VD and AM inhibited VSMCs proliferation stimulated with 5% fetal bovine serum and impaired cell migration. In further flow cytometry analysis 2VD treatment resulted in a partial cell cycle arrest at G2 phase. The OSCs tested were able to prevent ROS increase after angiotensin II stimulation and surprisingly 2VD induced higher total antioxidant status compared with AM and SAC. Our results showed that 2VD produces equivalent or superior beneficial effects on VSMCs to those reported for other bioavailable compounds of garlic. This preliminary evidence suggests that 2VD intake could also exert important protective effects against arterial remodeling in hypertension.
Keywords	angiotensin II ; animal disease models ; antihypertensive effect ; antioxidant activity ; bioavailability ; cell cycle checkpoints ; cell movement ; cell proliferation ; cell viability ; cysteine ; dyes ; fetal bovine serum ; flow cytometry ; garlic ; hypertension ; interphase ; myocytes ; oils ; oxidative stress ; protective effect ; rats ; reactive oxygen species ; smooth muscle ; tetrazolium ; toxicity testing ; covid19
Language	English
Dates of publication	2020-09
Size	p. 355-361.
Publishing place	Springer US
Document type	Article
ZDB-ID	221100-2
ISSN	1573-9104 ; 0921-9668
ISSN (online)	1573-9104
ISSN	0921-9668
DOI	10.1007/s11130-020-00819-x
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: 2-Vinyl-4H-1,3-Dithiin, a Bioavailable Compound from Garlic, Inhibits Vascular Smooth Muscle Cells Proliferation and Migration by Reducing Oxidative Stress.

Torres-Palazzolo, Carolina / de Paola, Matilde / Quesada, Isabel / Camargo, Alejandra / Castro, Claudia

Plant foods for human nutrition (Dordrecht, Netherlands)

2020 Volume 75, Issue 3, Page(s) 355–361

Abstract	Organosulfur compounds (OSCs) of garlic have various health benefits including anti-hypertensive effect. It has been described that volatile OSCs uptake occurs into a moderate extent. Among the bioavailable OSCs present in garlic, 2-vinyl-4H-1,3-dithiin (2VD) is a main component in garlic macerated oil and stir-fried garlic but has been poorly investigated compared with others OSCs, such allyl mercaptan (AM) and S-allyl cysteine (SAC). The aim of this study was to evaluate the effects of 2VD on vascular smooth muscle cells (VSMCs) isolated from spontaneous hypertensive rats (SHR) and compare them with those produced by AM and SAC. Cell viability and proliferation were measured using tetrazolium dye MTT assay and flow cytometry. Cell migration was evaluated by scrape-wound migration assay. OSCs anti-oxidative capacity was determined by measuring reactive oxygen species (ROS) generation, and total antioxidant status (TAS). Non-toxic plasmatic concentrations (10 μg L
MeSH term(s)	Animals ; Antioxidants ; Cell Proliferation ; Garlic ; Heterocyclic Compounds ; Muscle, Smooth, Vascular ; Oxidative Stress ; Rats ; Sulfur Compounds ; Vinyl Compounds
Chemical Substances	Antioxidants ; Heterocyclic Compounds ; Sulfur Compounds ; Vinyl Compounds ; 2-vinyl-4H-1,3-dithiin (80028-57-5)
Keywords	covid19
Language	English
Publishing date	2020-05-09
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	188869-9
ISSN	1573-9104 ; 0377-3205
ISSN (online)	1573-9104
ISSN	0377-3205
DOI	10.1007/s11130-020-00819-x
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Article ; Online: Mechanisms Suggesting a Relationship between Vitamin D and Erectile Dysfunction: An Overview.

Crafa, Andrea / Cannarella, Rossella / Barbagallo, Federica / Leanza, Claudia / Palazzolo, Roberto / Flores, Hunter Ausley / La Vignera, Sandro / Condorelli, Rosita A / Calogero, Aldo E

Biomolecules

2023 Volume 13, Issue 6

Abstract: Vitamin D deficiency (VDD) and erectile dysfunction (ED) heavily burden the male population. The higher prevalence of both conditions in the elderly suggests a possible relationship between the two conditions. In addition, in vitro, animal, and human ... ...

Abstract	Vitamin D deficiency (VDD) and erectile dysfunction (ED) heavily burden the male population. The higher prevalence of both conditions in the elderly suggests a possible relationship between the two conditions. In addition, in vitro, animal, and human studies have revealed several mechanisms that may relate VDD to ED. The main mechanism by which vitamin D might exert its action on sexual function appears to be through the regulation of endothelial function. Indeed, VDD correlates with several markers of endothelial function. The action of vitamin D on the endothelium would be exercised both indirectly through its intervention in inflammatory processes and through the production of oxygen free radicals, and directly through the regulation of vascular stiffness, the production of nitric oxide, and the regulation of vessel permeability. Furthermore, the ubiquitous distribution of the vitamin D receptor in the human body means that this hormone can also exert a beneficial effect on erectile function by interfering with those comorbidities significantly associated with ED, such as hypertension, diabetes mellitus, hypercholesterolemia, chronic kidney disease, and hypogonadism. In this review, we thoroughly and carefully presented the evidence and mechanisms that would appear to relate vitamin D levels to erectile function. Furthermore, we have summarized the meta-analytic evidence for and against this association to provide a true representation of this topic. Data published to date suggest that low levels of vitamin D could contribute to worsening erectile function through several mechanisms. Therefore, vitamin D levels should be measured in patients with ED and maintained at adequate levels by specific supplementation in case of deficiency. However, the low quality and heterogeneity of clinical trials evaluating the effects of vitamin D administration on erectile function and ED-associated comorbidities do not allow for a univocal conclusion, and indicate the need for further studies to analyze these aspects.
MeSH term(s)	Animals ; Male ; Humans ; Aged ; Erectile Dysfunction/drug therapy ; Erectile Dysfunction/epidemiology ; Erectile Dysfunction/complications ; Vitamin D/therapeutic use ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/drug therapy ; Vitamins ; Comorbidity
Chemical Substances	Vitamin D (1406-16-2) ; Vitamins
Language	English
Publishing date	2023-06-01
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2701262-1
ISSN	2218-273X ; 2218-273X
ISSN (online)	2218-273X
ISSN	2218-273X
DOI	10.3390/biom13060930
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Article ; Online: IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines.

Murri, Rita / Taccari, Francesco / Palazzolo, Claudia / Fantoni, Massimo / Cauda, Roberto

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

2018 Volume 66, Issue 11, Page(s) 1815–1816

MeSH term(s)	Communicable Diseases ; Humans ; Sepsis ; Shock, Septic
Language	English
Publishing date	2018-01-29
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	1099781-7
ISSN	1537-6591 ; 1058-4838
ISSN (online)	1537-6591
ISSN	1058-4838
DOI	10.1093/cid/cix1114
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Article ; Online: Consumption of oil macerated with garlic produces renovascular protective effects in adult apolipoprotein E-deficient mice.

Torres Palazzolo, Carolina / Martín Giménez, Virna Margarita / Mazzei, Luciana / De Paola, Matilde / Quesada, Isabel / Cuello Carrión, Fernando Darío / Fornés, Miguel Walter / Camargo, Alejandra Beatríz / Castro, Claudia / Manucha, Walter

Food & function

2022 Volume 13, Issue 15, Page(s) 8131–8142

Abstract: Oxidative stress and chronic inflammatory conditions contribute as key determinants in the development of vascular and renal diseases. Organosulfur compounds (OSCs) of oil macerated with garlic (OMG) are promising phytochemicals which could protect us ... ...

Abstract	Oxidative stress and chronic inflammatory conditions contribute as key determinants in the development of vascular and renal diseases. Organosulfur compounds (OSCs) of oil macerated with garlic (OMG) are promising phytochemicals which could protect us from hyper-inflammation and oxidative stress-induced organ damage. The present work evaluated the effect of OMG intake in apolipoprotein E-knockout (ApoE-KO) mice. Adult female ApoE-KO mice were randomly divided into three groups and fed with control chow, oil-supplemented diet and OMG-supplemented diet. After 8 weeks, the animals were euthanized and blood, aorta, kidneys, liver and abdominal adipose tissues were obtained for further analysis. Biochemical parameters were measured in plasma, lipid peroxidation as malondialdehyde (MDA) levels was determined in the adipose tissue, oil red O was used to stain atherosclerotic lesions, and histological and ultrastructural analyses of the kidneys were performed. Renal expression levels of Tumor Necrosis Factor α (TNF-α), Interleukin-6 (IL-6) and Wilms' Tumor Protein (WT-1) were determined by western blotting and the co-immunoprecipitation assay (p53/WT-1). Also, transmission electron microscopy for studying the expression of mitofusin 2 (Mfn-2) was used to assess mitochondrial damage. The results showed that long-term moderate intake of OMG improved serum triglyceride levels, diminished the atheroma plaque area, and reduced lipid peroxidation. Furthermore, we found a decrease in oxidative and inflammatory markers, less apoptosis and reduced WT-1 expression in the kidneys. Also, OMG increased p53/WT-1 protein interactions and reduced mitochondrial damage. Our findings suggest that OMG intake would produce anti-atherosclerotic, antifibrotic, anti-inflammatory and antiapoptotic effects in adult ApoE-KO mice, conferring significant renovascular protective actions in a mechanism mediated, at least in part, by WT-1.
MeSH term(s)	Animals ; Anti-Inflammatory Agents ; Antioxidants ; Apolipoproteins E/genetics ; Atherosclerosis/drug therapy ; Atherosclerosis/genetics ; Atherosclerosis/prevention & control ; Female ; Garlic ; Mice ; Mice, Knockout ; Tumor Suppressor Protein p53
Chemical Substances	Anti-Inflammatory Agents ; Antioxidants ; Apolipoproteins E ; Tumor Suppressor Protein p53
Language	English
Publishing date	2022-08-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2612033-1
ISSN	2042-650X ; 2042-6496
ISSN (online)	2042-650X
ISSN	2042-6496
DOI	10.1039/d2fo01509a
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Article ; Online: Effect of Garlic's Active Constituents in Inflammation, Obesity and Cardiovascular Disease.

Quesada, Isabel / de Paola, Matilde / Torres-Palazzolo, Carolina / Camargo, Alejandra / Ferder, León / Manucha, Walter / Castro, Claudia

Current hypertension reports

2020 Volume 22, Issue 1, Page(s) 6

Abstract: Purpose of review: Several studies have attributed garlic's beneficial properties to its high content of organosulfur compounds (OSCs). Here, we summarized recent studies published and some own findings regarding OSCs and its effects on cardiovascular ... ...

Abstract	Purpose of review: Several studies have attributed garlic's beneficial properties to its high content of organosulfur compounds (OSCs). Here, we summarized recent studies published and some own findings regarding OSCs and its effects on cardiovascular disease, inflammation, and obesity. Recent finding: The analysis of the multiple actions produced by OSCs suggests that many of its bioactivities interfere against inflammation, oxidative stress, obesogenic effects, and mitochondrial dysfunction. Accumulating evidence from in vitro, animal, and human studies reinforce the notion that OSCs modify signaling pathways that trigger chronic diseases, and to highlight, actions over these pathways are related to the treatment of disorders addressed in this review. Garlic's bioactive OSCs behave like a nutraceutical panacea because they cover a broad spectrum of applications with promising impact for the prevention and treatment of prevalent chronic pathologies associated with low-grade inflammation.
MeSH term(s)	Animals ; Cardiovascular Diseases/therapy ; Garlic ; Humans ; Hypertension/therapy ; Inflammation ; Obesity/therapy ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use
Chemical Substances	Plant Extracts
Language	English
Publishing date	2020-01-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2057367-4
ISSN	1534-3111 ; 1522-6417
ISSN (online)	1534-3111
ISSN	1522-6417
DOI	10.1007/s11906-019-1009-9
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