LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 221

Search options

  1. Article ; Online: Rare Case of Benign Prostatic Hyperplasia Causing Deep Vein Thrombosis.

    Kaur, Harveen / Chatterjee, Tulika / Bansal, Saurabh

    The American journal of medicine

    2023  Volume 136, Issue 11, Page(s) e218–e219

    Language English
    Publishing date 2023-07-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2023.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Cyanobacterial Harmful Algal Bloom Toxin Microcystin and Increased

    Chatterjee, Saurabh / More, Madhura

    Toxins

    2023  Volume 15, Issue 4

    Abstract: The effects of global warming are not limited to rising global temperatures and have set in motion a complex chain of events contributing to climate change. A consequence of global warming and the resultant climate change is the rise in cyanobacterial ... ...

    Abstract The effects of global warming are not limited to rising global temperatures and have set in motion a complex chain of events contributing to climate change. A consequence of global warming and the resultant climate change is the rise in cyanobacterial harmful algal blooms (cyano-HABs) across the world, which pose a threat to public health, aquatic biodiversity, and the livelihood of communities that depend on these water systems, such as farmers and fishers. An increase in cyano-HABs and their intensity is associated with an increase in the leakage of cyanotoxins. Microcystins (MCs) are hepatotoxins produced by some cyanobacterial species, and their organ toxicology has been extensively studied. Recent mouse studies suggest that MCs can induce gut resistome changes. Opportunistic pathogens such as
    MeSH term(s) Humans ; Animals ; Mice ; Microcystins/toxicity ; Harmful Algal Bloom ; Diabetes Mellitus, Type 2 ; Cyanobacteria Toxins ; Cyanobacteria ; Climate Change ; Liver ; Brain
    Chemical Substances microcystin (77238-39-2) ; Microcystins ; Cyanobacteria Toxins
    Language English
    Publishing date 2023-04-17
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins15040289
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Catestatin: Antimicrobial Functions and Potential Therapeutics.

    Jati, Suborno / Mahata, Sumana / Das, Soumita / Chatterjee, Saurabh / Mahata, Sushil K

    Pharmaceutics

    2023  Volume 15, Issue 5

    Abstract: The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout ... ...

    Abstract The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant "superbugs". The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA
    Language English
    Publishing date 2023-05-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics15051550
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Host microbiome associated low intestinal acetate correlates with progressive NLRP3-dependent hepatic-immunotoxicity in early life microcystin-LR exposure.

    More, Madhura / Chatterjee, Somdatta / Saha, Punnag / Bose, Dipro / Trivedi, Ayushi / Roy, Subhajit / Chatterjee, Saurabh

    BMC pharmacology & toxicology

    2023  Volume 24, Issue 1, Page(s) 78

    Abstract: Background: Microcystins (MCs), potent hepatotoxins pose a significant health risk to humans, particularly children, who are more vulnerable due to higher water intake and increased exposure during recreational activities.: Methods: Here, we ... ...

    Abstract Background: Microcystins (MCs), potent hepatotoxins pose a significant health risk to humans, particularly children, who are more vulnerable due to higher water intake and increased exposure during recreational activities.
    Methods: Here, we investigated the role of host microbiome-linked acetate in modulating inflammation caused by early-life exposure to the cyanotoxin Microcystin-LR (MC-LR) in a juvenile mice model.
    Results: Our study revealed that early-life MC-LR exposure disrupted the gut microbiome, leading to a depletion of key acetate-producing bacteria and decreased luminal acetate concentration. Consequently, the dysbiosis hindered the establishment of a gut homeostatic microenvironment and disrupted gut barrier function. The NOD-like receptor family pyrin domain - containing 3 (NLRP3) inflammasome, a key player in MC-induced hepatoxicity emerged as a central player in this process, with acetate supplementation effectively preventing NLRP3 inflammasome activation, attenuating hepatic inflammation, and decreasing pro-inflammatory cytokine production. To elucidate the mechanism underlying the association between early-life MC-LR exposure and the progression of metabolic dysfunction associated steatotic liver disease (MASLD), we investigated the role of acetate binding to its receptor -G-protein coupled receptor 43 (GPR43) on NLRP3 inflammasome activation. Our results demonstrated that acetate-GPR43 signaling was crucial for decreasing NLRP3 protein levels and inhibiting NLRP3 inflammasome assembly. Further, acetate-induced decrease in NLRP3 protein levels was likely mediated through proteasomal degradation rather than autophagy. Overall, our findings underscore the significance of a healthy gut microbiome and its metabolites, particularly acetate, in the progression of hepatotoxicity induced by early life toxin exposure, crucial for MASLD progression.
    Conclusions: This study highlights potential therapeutic targets in gut dysbiosis and NLRP3 inflammasome activation for mitigating toxin-associated inflammatory liver diseases.
    MeSH term(s) Animals ; Mice ; Acetates ; Dysbiosis/chemically induced ; Gastrointestinal Microbiome ; Inflammasomes ; Inflammation/drug therapy ; Microcystins/toxicity ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism
    Chemical Substances Acetates ; cyanoginosin LR (EQ8332842Y) ; Inflammasomes ; Microcystins ; NLR Family, Pyrin Domain-Containing 3 Protein
    Language English
    Publishing date 2023-12-13
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2680259-4
    ISSN 2050-6511 ; 2050-6511
    ISSN (online) 2050-6511
    ISSN 2050-6511
    DOI 10.1186/s40360-023-00721-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Recent changes in Indian monsoon in light of regionalization based on various rain features

    Chatterjee, Chandrani / Das, Saurabh

    Theoretical and applied climatology. 2021 Nov., v. 146, no. 3-4

    2021  

    Abstract: The effect of climate change on precipitation pattern is emerging out as a serious global challenge. However, the quantification and assessment of the climate change effect on precipitation are a challenging issue given the spatio-temporal inhomogeneity ... ...

    Abstract The effect of climate change on precipitation pattern is emerging out as a serious global challenge. However, the quantification and assessment of the climate change effect on precipitation are a challenging issue given the spatio-temporal inhomogeneity of rainfall. Previous studies mostly used only rain intensity information for the identification of climate change signature by selecting homogeneous rain regions. Rain climatology, however, has several other important characteristics like occurrence of multiple rain type, occurrence of extreme rain events and their spatial distribution. The present study provides a novel approach to combine satellite data with ground measurements for addressing this issue. In this study, the Indian subcontinent has been divided into homogeneous regions based on six different rain features, obtained from ground observations and TRMM satellite measurements of 12 years, using K-medoid clustering technique. The rain features showed distinguishable patterns in the resulting nine homogeneous rain zones and distinct behavioural patterns in the inter-relationships between the various rain features. To verify the consistency of the proposed regionalization, the recent changes in mean monsoon rain rates are then studied using 40 years of rain gauge measurements for these regions. Increasing trends in monsoon rain are observed in two homogeneous regions whereas five of them have shown decreasing signature of rain intensity. Although the present study focused only on monsoon rain over India, the results indicate the suitability of the proposed method as an efficient technique of identifying homogeneous region for other seasons and locations as well.
    Keywords climate change ; climatology ; monsoon season ; rain ; rain gauges ; rain intensity ; remote sensing ; satellites ; India
    Language English
    Dates of publication 2021-11
    Size p. 1007-1018.
    Publishing place Springer Vienna
    Document type Article
    ZDB-ID 1463177-5
    ISSN 1434-4483 ; 0177-798X
    ISSN (online) 1434-4483
    ISSN 0177-798X
    DOI 10.1007/s00704-021-03781-z
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: An Investigation on Super- and Sub-Terminal Drops in Two Different Rain Categories and Climate Regimes

    Chandrani Chatterjee / Federico Porcù / Saurabh Das / Alessandro Bracci

    Remote Sensing, Vol 14, Iss 2515, p

    2022  Volume 2515

    Abstract: The pressing need for accurate and reliable precipitation measurements and forecasting poses theoretical and technological problems. Remote-sensing instruments with increased coverage and sensitivity (such as space-borne and ground-based radar) are ... ...

    Abstract The pressing need for accurate and reliable precipitation measurements and forecasting poses theoretical and technological problems. Remote-sensing instruments with increased coverage and sensitivity (such as space-borne and ground-based radar) are available; however, their full exploitation requires physical calibration and validation based on a deep knowledge of precipitation microphysics. This study reports a detailed analysis of the evidence of non-terminal velocities in a mid-latitude (Bologna, Italy) and a tropical location (Kolkata, India). The data from two identical disdrometers OTT-Parsivel2 were analyzed to shed light on the nature of the raindrops that fall at a velocity that is significantly higher (i.e., super-terminal drops) or lower (sub-terminal drops) than the terminal velocity expected for the raindrop sizes. The results show a significant fraction of super- and sub-terminal drops in both locations. The percentages of both super- and sub-terminal drops were higher in Kolkata. However, the difference was more notable for convective rain. The percentages of both super- and sub-terminal drops were found to be high within a drop diameter of 1 mm. The number of sub-terminal drops seemed to increase with an increase in diameter for drops larger than ~2.5 mm. The natural rain in Bologna showed stronger evidence of drop break-up in correspondence with the evolution of non-terminal velocities. Moreover, this study once again pointed toward the fact that the process of break-up cannot be neglected in natural rain of tropical or mid-latitude locations. We found that 7% and 10% of rain samples in Bologna and Kolkata seemed to be subjected to drop break-up. The results indicate that radar measurements of rain in the tropics or mid-latitude regions, relying on the Gunn–Kinzer relationship between velocity and diameter, should be verified by observations of disdrometers for a high precision QPE.
    Keywords super-terminal ; sub-terminal ; break-up ; tropics ; mid-latitude ; disdrometer ; Science ; Q
    Subject code 290
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article: Resection of Osteoid Osteoma Using Three-Dimensional (3D) Printing.

    Krishna, Sathya Vamsi / Gupta, Saurabh Kumar / Holla, Navaneeth / Chatterjee, Kaushik

    Indian journal of orthopaedics

    2022  Volume 56, Issue 9, Page(s) 1657–1661

    Abstract: Using computed tomography scans, we were able to treat symptomatic osteoid osteoma of the distal radius with the help of 3D printing technology that involves designing bone models and fabricating surgical guides to locate the tumour precisely and resect ... ...

    Abstract Using computed tomography scans, we were able to treat symptomatic osteoid osteoma of the distal radius with the help of 3D printing technology that involves designing bone models and fabricating surgical guides to locate the tumour precisely and resect it successfully with limited exposure without the use of any intraoperative imaging. This is a new technology that can be applied to treat bony lesions and can be an alternative solution to currently available techniques.
    Language English
    Publishing date 2022-07-02
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 603194-8
    ISSN 0019-5413
    ISSN 0019-5413
    DOI 10.1007/s43465-022-00689-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1720: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Utilizing coordination chemistry through formation of a Cu

    Chatterjee, Sayantani / Jain, Chetan Kumar / Saha, Tanmoy / Roychoudhury, Susanta / Majumder, Hemanta Kumar / Das, Saurabh

    Journal of inorganic biochemistry

    2023  Volume 249, Page(s) 112369

    Abstract: Quinalizarin, an analogue of anthracycline anticancer agents, is an anticancer agent itself. A ... ...

    Abstract Quinalizarin, an analogue of anthracycline anticancer agents, is an anticancer agent itself. A Cu
    MeSH term(s) Humans ; DNA Topoisomerases, Type I/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antibiotics, Antineoplastic ; Topoisomerase II Inhibitors/pharmacology ; Superoxides/metabolism ; Anthracyclines ; Free Radicals/metabolism ; Copper/chemistry ; Coordination Complexes/chemistry
    Chemical Substances 1,2,5,8-tetrahydroxy anthraquinone (6D43C3LYSG) ; DNA Topoisomerases, Type I (EC 5.99.1.2) ; Antineoplastic Agents ; Antibiotics, Antineoplastic ; Topoisomerase II Inhibitors ; Superoxides (11062-77-4) ; Anthracyclines ; Free Radicals ; Copper (789U1901C5) ; Coordination Complexes
    Language English
    Publishing date 2023-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 162843-4
    ISSN 1873-3344 ; 0162-0134
    ISSN (online) 1873-3344
    ISSN 0162-0134
    DOI 10.1016/j.jinorgbio.2023.112369
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1730: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: Deaths due to delayed presentation to the hospital from fear of contracting COVID-19 during lockdown period: a tertiary care center experience.

    Bansal, Saurabh / Roy, Moni / Chatterjee, Tulika / Roy, Ashish Kumar

    Journal of community hospital internal medicine perspectives

    2021  Volume 11, Issue 3, Page(s) 299–301

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2021-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2616884-4
    ISSN 2000-9666
    ISSN 2000-9666
    DOI 10.1080/20009666.2021.1918440
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Proteome changes in larval zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) exposed to (±) anatoxin-a.

    Langan, Laura M / Lovin, Lea M / Taylor, Raegyn B / Scarlett, Kendall R / Kevin Chambliss, C / Chatterjee, Saurabh / Scott, J Thad / Brooks, Bryan W

    Environment international

    2024  Volume 185, Page(s) 108514

    Abstract: Anatoxin-a and its analogues are potent neurotoxins produced by several genera of cyanobacteria. Due in part to its high toxicity and potential presence in drinking water, these toxins pose threats to public health, companion animals and the environment. ...

    Abstract Anatoxin-a and its analogues are potent neurotoxins produced by several genera of cyanobacteria. Due in part to its high toxicity and potential presence in drinking water, these toxins pose threats to public health, companion animals and the environment. It primarily exerts toxicity as a cholinergic agonist, with high affinity at neuromuscular junctions, but molecular mechanisms by which it elicits toxicological responses are not fully understood. To advance understanding of this cyanobacteria, proteomic characterization (DIA shotgun proteomics) of two common fish models (zebrafish and fathead minnow) was performed following  (±) anatoxin-a exposure. Specifically, proteome changes were identified and quantified in larval fish exposed for 96 h (0.01-3 mg/L (±) anatoxin-a and caffeine (a methodological positive control) with environmentally relevant treatment levels examined based on environmental exposure distributions of surface water data. Proteomic concentration - response relationships revealed 48 and 29 proteins with concentration - response relationships curves for zebrafish and fathead minnow, respectively. In contrast, the highest number of differentially expressed proteins (DEPs) varied between zebrafish (n = 145) and fathead minnow (n = 300), with only fatheads displaying DEPs at all treatment levels. For both species, genes associated with reproduction were significantly downregulated, with pathways analysis that broadly clustered genes into groups associated with DNA repair mechanisms. Importantly, significant differences in proteome response between the species was also observed, consistent with prior observations of differences in response using both behavioral assays and gene expression, adding further support to model specific differences in organismal sensitivity and/or response. When DEPs were read across from humans to zebrafish, disease ontology enrichment identified diseases associated with cognition and muscle weakness consistent with the prior literature. Our observations highlight limited knowledge of how (±) anatoxin-a, a commonly used synthetic racemate surrogate, elicits responses at a molecular level and advances its toxicological understanding.
    MeSH term(s) Animals ; Humans ; Zebrafish/metabolism ; Proteome/metabolism ; Larva ; Proteomics ; Cyprinidae/metabolism ; Water Pollutants, Chemical/toxicity ; Cyanobacteria Toxins ; Tropanes
    Chemical Substances anatoxin a (80023A73NK) ; Proteome ; Water Pollutants, Chemical ; Cyanobacteria Toxins ; Tropanes
    Language English
    Publishing date 2024-02-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 554791-x
    ISSN 1873-6750 ; 0160-4120
    ISSN (online) 1873-6750
    ISSN 0160-4120
    DOI 10.1016/j.envint.2024.108514
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3131: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top