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  1. Conference proceedings: Behandlung der neovaskulären altersbedingten Makuladegeneration (nAMD) mit intravitrealem Aflibercept (IVT-AFL) in einem Treat-and-Extend (T&E)-Regime: Post-hoc-Analyse zum intensiven Injektionsbedarf (I-I-Bedarf) bei Patienten der ARIES-Studie

    Pielen, Amelie / Wolf, S. / Holz, F.G. / Hykin, P. / Midena, E. / Souied, E. / Lambrou, G. / Machewitz, T. / Allmeier, H. / Mitchell, P.

    2021  , Page(s) 21rg02

    Event/congress 33. Jahrestagung der Retinologischen Gesellschaft; München (digital); Retinologische Gesellschaft; 2021
    Keywords Medizin, Gesundheit
    Publishing date 2021-06-24
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/21rg02
    Database German Medical Science

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  2. Conference proceedings: Zusammenhang zwischen Sehschärfe und intraretinaler (IRF) oder subretinaler (SRF) Flüssigkeit bei Patienten mit neovaskulärer altersbedingter Makuladegeneration (nAMD), die ein Treat-and-Extend-Regime (T&E) mit intravitrealem Aflibercept (IVT-AFL) erhielten: eine Post-hoc-Analyse der ARIES-Studie

    Wolf, Sebastian / Chaudhary, V. / Holz, F.G. / Hykin, P. / Midena, E. / Souied, E. / Machewitz, T. / Lambrou, G. / Mitchell, P.

    2021  , Page(s) 21rg03

    Event/congress 33. Jahrestagung der Retinologischen Gesellschaft; München (digital); Retinologische Gesellschaft; 2021
    Keywords Medizin, Gesundheit
    Publishing date 2021-06-24
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/21rg03
    Database German Medical Science

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  3. Article ; Online: Multimodal and retro-mode imaging in sclerochoroidal calcification: A case report.

    Lopez, J M / Rabinovich, M / Colantuono, D / Souied, E H

    Archivos de la Sociedad Espanola de Oftalmologia

    2024  Volume 99, Issue 5, Page(s) 213–217

    Abstract: We present a case report on sclerochoroidal calcification (SCC), a rare condition involving calcium pyrophosphate deposits in the posterior pole of the eye in a 70-year-old patient. We provide an account of the clinical presentation and its appearance in ...

    Abstract We present a case report on sclerochoroidal calcification (SCC), a rare condition involving calcium pyrophosphate deposits in the posterior pole of the eye in a 70-year-old patient. We provide an account of the clinical presentation and its appearance in multimodal images, using color fundus photography, swept-source optical coherence tomography (SS-OCT), ocular ultrasound, and the novel retro-mode imaging (RMI) technique. Visual acuity was 20/25 in the right eye (OD) and 20/20 in the left eye (OS). Color fundus photography revealed yellowish deposits located in the upper temporal arcade of both eyes. SS-OCT demonstrated masses of scleral origin. Ocular ultrasounds confirmed the calcification of these masses. RMI detected hyper-reflective images with marked superficial elevation. Systemic laboratory results did not detect any abnormalities, leading to the diagnosis of bilateral idiopathic SCC.
    MeSH term(s) Humans ; Aged ; Scleral Diseases/diagnostic imaging ; Multimodal Imaging ; Calcinosis/diagnostic imaging ; Tomography, Optical Coherence ; Choroid Diseases/diagnostic imaging ; Male ; Ultrasonography
    Language English
    Publishing date 2024-02-09
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ISSN 2173-5794
    ISSN (online) 2173-5794
    DOI 10.1016/j.oftale.2024.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prévention nutritionnelle de la dégénérescence maculaire liée à l'âge

    Souied, Éric

    La Revue du praticien

    2018  Volume 67, Issue 1, Page(s) 102–104

    Abstract: Nutritional prevention of age-related macular degeneration. Age-related macular degeneration is the leading cause of blindness in industrialized countries. Nowadays, the treatments of this chronic pathology do not make it possible to avoid the visual ... ...

    Title translation Nutritional prevention of age-related macular degeneration.
    Abstract Nutritional prevention of age-related macular degeneration. Age-related macular degeneration is the leading cause of blindness in industrialized countries. Nowadays, the treatments of this chronic pathology do not make it possible to avoid the visual loss in the long term. Nutritional prevention thus remains an indispensable means to delay the consequences of this pathology. This article reports the various nutrients that have proved their worth in the prevention of AMD.
    MeSH term(s) Diet ; Humans ; Macular Degeneration/prevention & control
    Language French
    Publishing date 2018-12-03
    Publishing country France
    Document type Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: OCT angiography in retinal and macular diseases

    Bandello, Francesco / Souied, Eric H. / Querques, Giuseppe

    (Developments in ophthalmology ; 56)

    2016  

    Series title Developments in ophthalmology ; 56
    Collection
    Keywords Ophthalmology ; Makulopathie ; Netzhautkrankheit ; Optische Kohärenztomografie ; Angiographie
    Subject Angioradiographie ; Vasographie ; Gefäßdarstellung ; Optische Kohärenztomographie ; OCT ; Optical coherence tomography ; Netzhauterkrankung ; Maculakrankheit ; Makulakrankheit ; Maculopathie ; Makulaforamen ; MFO
    Language English
    Size XI, 184 S. : zahlr. Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018943266
    ISBN 978-3-318-05829-1 ; 3-318-05829-7
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Cognitive bias evaluation on the choice of treatment in common retinal disorders among retina specialists in 2023.

    Niegowski, L-J / Cohen, S Y / Crincoli, E / Mehanna, C J / Souied, E H

    Journal francais d'ophtalmologie

    2024  Volume 47, Issue 6, Page(s) 104177

    Abstract: Purpose: The study aimed to discern the intent to treat with the therapeutic agents prescribed first or second line in the following eye conditions: neovascular age-related macular Degeneration (nAMD), diabetic macular edema (DME), retinal vein ... ...

    Abstract Purpose: The study aimed to discern the intent to treat with the therapeutic agents prescribed first or second line in the following eye conditions: neovascular age-related macular Degeneration (nAMD), diabetic macular edema (DME), retinal vein occlusion (RVO), and myopic maculopathy with choroidal neovascularization (MMNV). The study also aimed to distinguish the ophthalmologists' intended treatment for their patients from those that they would prescribe for themselves if they were affected by the above macular conditions.
    Methods: The study utilized an online survey of 243 French ophthalmologists practicing medical retina, with males accounting for 54.3% of the participants. Data was obtained using a questionnaire that focused on the ophthalmologists' experience with various agents as well as their first and second line choices for nAMD, DME, RVO, and MMNV.
    Results: The vast majority of French ophthalmologists (99%) had experience with the most widely used anti-vascular endothelial growth factors (anti-VEGFs); ranibizumab, bevacizumab, and aflibercept. Fewer than 8% reported experience with anti-VEGF drug reservoirs, biosimilars, or faricimab. The study findings also showed ranibizumab and aflibercept as the commonly prescribed first line choices for the above-mentioned ocular conditions. For the second line choice, the study showed that aflibercept and dexamethasone intravitreal implants were the most common across the four retinal conditions studied. The only difference in intent to treat for "patients" versus "yourself" was for biosimilars (0% to 0.8%, P=0.001).
    Conclusion: The findings regarding the first and second line choices for the mentioned ocular disorders were found to agree with the findings of published literature currently used in practice, with a tendency to prefer ranibizumab as first line therapy for neovascular disorders and aflibercept as first line therapy for macular edema. In addition, there were no differences between choices for first and second line therapy for patients vs. ophthalmologists.
    Language English
    Publishing date 2024-04-10
    Publishing country France
    Document type Journal Article
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2024.104177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: In vivo cone-photoreceptor density comparison between eyes with subretinal drusenoid deposits and healthy eyes using high magnification imaging.

    El Ghazi, Djazia / Miere, Alexandra / Crincoli, Emanuele / Le, Hoang Mai / Souied, Eric H

    International ophthalmology

    2024  Volume 44, Issue 1, Page(s) 82

    Abstract: ... standard deviation foci detected (i.e., cone photoreceptors) was 7123.75 ± 3683.32 foci/mm: Conclusion ...

    Abstract Purpose: To compare photoreceptor density automated quantification in eyes with subretinal drusenoid deposits (SDD) and healthy controls using Heidelberg Spectralis High Magnification Module (HMM) imaging.
    Methods: Twelve eyes of 6 patients with intermediate AMD, presenting with SDD were included, as well as twelve eyes of healthy controls. Individual dot SDD within the central 30° retina were examined with infrared confocal laser ophthalmoscopy, HMM, and spectral-domain optical coherence tomography (SD-OCT). Photoreceptor density analysis was performed on the best-quality image using the ImageJ Foci Picker plugin, after the removal of SDD from the HMM image. Correlations were made between the HMM quantified photoreceptor density, SD-OCT characteristics, stage, and number of SDD.
    Results: Mean age was 75.17 ± 2.51 years in the SDD group (3 males, 3 females) versus 73.17 ± 3.15 years in the healthy control group (p = 0.2). Defects in the overlying ellipsoid zone were present on SD-OCT in 8/12 (66.66%) eyes. The mean ± standard deviation foci detected (i.e., cone photoreceptors) was 7123.75 ± 3683.32 foci/mm
    Conclusion: The decreased cone density in eyes with SDD may correlate with a decrease in retinal function in intermediate AMD eyes independent of neovascular complications or outer retinal pigment epithelial atrophy.
    MeSH term(s) Female ; Male ; Humans ; Aged ; Retinal Cone Photoreceptor Cells ; Retina ; Tomography, Optical Coherence ; Ophthalmoscopy ; Health Status
    Language English
    Publishing date 2024-02-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-024-03023-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Re: Agrón et al.: Reticular pseudodrusen status, ARMS2/HTRA1 genotype, and geographic atrophy enlargement: Age-Related Eye Disease Study 2 Report 32. (Ophthalmology. 2022;129:1107-1119).

    Bhuiyan, Alauddin / Souied, Eric / Allikmets, Rando L / Smith, R Theodore

    Ophthalmology

    2023  Volume 130, Issue 7, Page(s) e26–e27

    MeSH term(s) Humans ; Geographic Atrophy/diagnosis ; Geographic Atrophy/genetics ; Retinal Drusen/diagnosis ; Retinal Drusen/genetics ; Genotype ; High-Temperature Requirement A Serine Peptidase 1/genetics ; Polymorphism, Single Nucleotide ; Proteins/genetics
    Chemical Substances High-Temperature Requirement A Serine Peptidase 1 (EC 3.4.21.-) ; ARMS2 protein, human ; Proteins
    Language English
    Publishing date 2023-04-27
    Publishing country United States
    Document type Letter
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.03.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Neuropathy, ataxia, retinitis pigmentosa: a case of a mother and two siblings.

    Rabinovich, Mark / Zambrowski, Olivia / Miere, Alexandra / Bhouri, Rakia / Souied, Eric

    Ophthalmic genetics

    2023  Volume 45, Issue 2, Page(s) 193–200

    Abstract: Aim: We describe the ophthalmic manifestations of Neuropathy, ataxia, retinitis pigmentosa (NARP) syndrome in three related patients.: Methods: We examined a mother and her two children, who were carriers of the : Results: All patients had the ... ...

    Abstract Aim: We describe the ophthalmic manifestations of Neuropathy, ataxia, retinitis pigmentosa (NARP) syndrome in three related patients.
    Methods: We examined a mother and her two children, who were carriers of the
    Results: All patients had the clinical manifestations of NARP syndrome, which were variably expressed symptomatically, on the fundus exams, electroretinogram, and visual fields.
    Conclusions: Once genetically established, NARP syndrome, as other mitochondrial disorders, has a very variable progression with different degrees of severity. A multimodal approach involving both neurological and ophthalmological diagnosis of NARP syndrome is necessary in order to establish the course of the disease and the measures to be taken.
    MeSH term(s) Child ; Female ; Humans ; Mothers ; Siblings ; Retinitis Pigmentosa/diagnosis ; Retinitis Pigmentosa/genetics ; Ataxia/diagnosis ; Ataxia/genetics ; Mutation ; Tomography, Optical Coherence ; Hypopituitarism ; Mitochondrial Myopathies
    Language English
    Publishing date 2023-09-06
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1199279-7
    ISSN 1744-5094 ; 0167-6784 ; 1381-6810
    ISSN (online) 1744-5094
    ISSN 0167-6784 ; 1381-6810
    DOI 10.1080/13816810.2023.2253905
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Foveal Hypoplasia in a Patient With High Myopia: Clinical and Imaging Diagnosis.

    Zloto, Ofira / Souied, Eric / Blanco-Garavito, Rocio

    Journal of pediatric ophthalmology and strabismus

    2022  Volume 59, Issue 2, Page(s) e23–e24

    Abstract: The authors present an unusual case of a 6-year-old boy with myopia and foveal hypoplasia who was diagnosed by optical coherence tomography angiography. This case report presents the importance of using optical coherence tomography angiography in the ... ...

    Abstract The authors present an unusual case of a 6-year-old boy with myopia and foveal hypoplasia who was diagnosed by optical coherence tomography angiography. This case report presents the importance of using optical coherence tomography angiography in the diagnosis of a different etiology.
    MeSH term(s) Child ; Fluorescein Angiography/methods ; Fovea Centralis ; Fundus Oculi ; Humans ; Male ; Myopia/complications ; Myopia/diagnosis ; Visual Acuity
    Language English
    Publishing date 2022-03-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 800921-1
    ISSN 1938-2405 ; 0191-3913
    ISSN (online) 1938-2405
    ISSN 0191-3913
    DOI 10.3928/01913913-20220124-03
    Database MEDical Literature Analysis and Retrieval System OnLINE

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