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  1. Article ; Online: Peer review report 3 on “Is performing lobectomy after the use of bevacizumab for a lung tumor dangerous?”

    Soner Gürsoy

    Annals of Medicine and Surgery, Vol 5, Iss S1, p S

    2016  Volume 89

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: The impact of dissection of station 9 on survival and the necessity of pulmonary ligament division during upper lobectomy for lung cancer.

    Yazgan, Serkan / Üçvet, Ahmet / Türk, Yunus / Gürsoy, Soner

    Acta chirurgica Belgica

    2021  Volume 123, Issue 2, Page(s) 148–155

    Abstract: Background: We conducted this study to investigate the need for dissection of station 9 lymph nodes during upper lobectomy for non-small-cell lung cancer (NSCLC) and to find out the operative results of inferior pulmonary ligament division.: Methods: ...

    Abstract Background: We conducted this study to investigate the need for dissection of station 9 lymph nodes during upper lobectomy for non-small-cell lung cancer (NSCLC) and to find out the operative results of inferior pulmonary ligament division.
    Methods: A total of 840 patients who underwent upper lobectomy for NSCLC between January 2007 and June 2020 were evaluated retrospectively. The patients were separated into two groups - those having undergone lymph node dissection of station 9 and inferior pulmonary ligament dissection (Group I) and those who did not (Group II). In these groups, the prognostic value of station 9 lymph nodes and postoperative effects (drainage time, prolonged air leak, dead space and length of hospital stay) of ligament division or preservation were analyzed.
    Results: The number of patients with station 9 lymph node metastasis was only one (0.1%) and that was multi-station pN2 disease. Station 9 lymph nodes were found in 675 (80.4%) patients, while 22 (2.6%) patients had no lymph nodes in the dissected material. In the other 143 (17%) patients, the inferior pulmonary ligament and station 9 were not dissected. While 5-year survival was 64.9% in 697 patients of Group I, it was 61.3% in 143 patients of Group II (
    Conclusions: In upper lobectomies, status of station 9 does not have a significant impact on patients' survival and lymph node staging. Additionally, preservation or division of the inferior pulmonary ligament has no significant advantage or disadvantage.
    MeSH term(s) Humans ; Lung Neoplasms/pathology ; Carcinoma, Non-Small-Cell Lung/pathology ; Retrospective Studies ; Lymphatic Metastasis ; Lymph Node Excision/methods ; Pneumonectomy/methods ; Ligaments ; Neoplasm Staging
    Language English
    Publishing date 2021-07-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 210274-2
    ISSN 0001-5458
    ISSN 0001-5458
    DOI 10.1080/00015458.2021.1958189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Changes in the Surgical Treatment Strategies for Nonsmall Cell Lung Cancer in the Past 20 Years: A Single-Center Experience.

    Üçvet, Ahmet / Gürsoy, Soner / Yazgan, Serkan

    Turkish thoracic journal

    2020  Volume 21, Issue 1, Page(s) 8–13

    Abstract: Objectives: Nonsmall cell lung cancer (NSCLC) is a multifactorial disease, and differences in the characteristics of surgical patients may develop over the years. This study aimed to evaluate the patients who underwent curative surgical resection for ... ...

    Abstract Objectives: Nonsmall cell lung cancer (NSCLC) is a multifactorial disease, and differences in the characteristics of surgical patients may develop over the years. This study aimed to evaluate the patients who underwent curative surgical resection for NSCLC in the past 20 years at our center and analyze the changes in the treatment strategies based on demographics, surgical strategies, and histopathology.
    Materials and methods: In this retrospective single-center cohort study, 1995 patients who had undergone lobectomy, bilobectomy, or pneumonectomy for primary NSCLC from January 1997 to January 2017 were analyzed. Patients were divided into two groups: Group I included patients operated in the first 10 years and Group II included patients operated in the last 10 years.
    Results: Overall, 77% of patients were operated in the last 10 years (458 vs. 1537 patients). Sleeve lobectomies performed in Group II reduced the rate of pneumonectomy from 37% to 20% (p<0.001). The operation rates for adenocarcinomas increased significantly during the study period, increasing from 31.4% to 36.2% (p=0.049). The 30- and 90-day postoperative mortality rates were 4.6% and 8.5% in Group I and 4.1% and 5.7% in Group II, respectively (p=0.69 and p=0.037, respectively). When the groups were compared, the median and 5-year survival rates were 44.1 months (95% confidence interval [CI], 35.6-52.6) and 42.9% in Group I and 73.6 months (95% CI, 63.3-83.9) and 53.9% in Group II, respectively (p<0.001).
    Conclusion: This study demonstrates an improvement in long-term outcomes following lung cancer surgery with an increasing rate of surgical procedures in the last 10 years. There was an increase in the proportion of females affected and the rate of adenocarcinoma. However, the pneumonectomy and postoperative N2 disease rates have decreased with advancing preoperative evaluation techniques and parenchyma-saving surgical methods. Postoperative mortality has decreased, and the survival rate has increased.
    Language English
    Publishing date 2020-01-01
    Publishing country Turkey
    Document type Journal Article
    ISSN 2149-2530
    ISSN (online) 2149-2530
    DOI 10.5152/TurkThoracJ.2019.180124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Surgery in congenital lung malformations: the evolution from thoracotomy to VATS, 10-year experience in a single center.

    Ceylan, Kenan C / Batihan, Güntuğ / Üçvet, Ahmet / Gürsoy, Soner

    Journal of cardiothoracic surgery

    2021  Volume 16, Issue 1, Page(s) 131

    Abstract: Background: Congenital lung malformation is an umbrella term and consist of various kind of parenchymal and mediastinal pathologies. Surgical resection is often required for diagnosis and curative treatment. We aimed to review our experience in surgical ...

    Abstract Background: Congenital lung malformation is an umbrella term and consist of various kind of parenchymal and mediastinal pathologies. Surgical resection is often required for diagnosis and curative treatment. We aimed to review our experience in surgical treatment for congenital lung disease and present the role of minimally invasive surgery.
    Methods: Surgical resections performed for benign lesions of the lung and mediastinum between January 2009 and May 2019 were retrospectively analyzed. Patients who were found to have congenital lung malformation as a result of pathological examination were included in our study. Distribution characteristics of the patients according to congenital lung malformation subtypes, differences in surgical approach and postoperative results were investigated.
    Results: A total of 94 patients who underwent surgical resection and were diagnosed with the bronchogenic cyst, sequestration, bronchial atresia, congenital cystic adenomatoid malformation (CCAM), or enteric cyst as a result of pathological examination were included the study. There were no significant differences between pathological subtypes in the postoperative length of hospital stay and drainage duration however, perioperative complication rate was higher in the sequestration group. In addition, in the first three days postoperatively, the mean pain score was found to be lower in the VATS group compared to thoracotomy.
    Conclusions: Congenital lung malformations consist of a heterogeneous group of diseases and the surgical treatment in these patients can range from a simple cyst excision to pneumonectomy. Video-assisted thoracoscopic surgery should be considered as the first choice in the surgical treatment of these patients in experienced centers.
    MeSH term(s) Adolescent ; Adult ; Aged ; Bronchial Diseases/surgery ; Bronchogenic Cyst/surgery ; Cystic Adenomatoid Malformation of Lung, Congenital/surgery ; Female ; Humans ; Length of Stay ; Lung/surgery ; Lung Diseases/congenital ; Lung Diseases/surgery ; Male ; Middle Aged ; Minimally Invasive Surgical Procedures ; Pneumonectomy/methods ; Postoperative Period ; Retrospective Studies ; Thoracic Surgery, Video-Assisted/methods ; Thoracotomy/methods ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2021-05-17
    Publishing country England
    Document type Journal Article
    ISSN 1749-8090
    ISSN (online) 1749-8090
    DOI 10.1186/s13019-021-01511-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Video-assisted thoracoscopic lobectomy and bilobectomy versus open thoracotomy for non-small cell lung cancer: Mortality and survival.

    Üçvet, Ahmet / Yazgan, Serkan / Samancılar, Özgür / Türk, Yunus / Gürsoy, Soner / Erbaycu, Ahmet Emin

    Turk gogus kalp damar cerrahisi dergisi

    2022  Volume 30, Issue 1, Page(s) 66–74

    Abstract: Background: In this study, we aimed to evaluate patients who had non-small cell lung cancer and underwent resection, to investigate our tendency to prefer video-assisted thoracic surgery or open thoracotomy, and to compare 30- and 90-day mortalities and ...

    Abstract Background: In this study, we aimed to evaluate patients who had non-small cell lung cancer and underwent resection, to investigate our tendency to prefer video-assisted thoracic surgery or open thoracotomy, and to compare 30- and 90-day mortalities and survival rates.
    Methods: Between January 2013 and January 2019, a total of 706 patients (577 males, 129 females; mean age: 61.9±8.6 years; range, 17 to 84 years) who underwent lobectomy or bilobectomy due to primary non-small cell lung cancer were retrospectively analyzed. The patients were divided into two groups as operated on through video-assisted thoracic surgery and through open thoracotomy. The 30- and 90-day mortality rates and survival rates were compared.
    Results: Of the patients, 202 (28.6%) underwent video-assisted thoracic surgery and 504 (71.4%) underwent open thoracotomy. Lobectomy was performed in 632 patients (89.5%) and bilobectomy was performed in 74 patients (10.5%). Patients who were chosen for video-assisted thoracic surgery were statistically significantly older, did not require any procedure other than lobectomy, did not receive neoadjuvant therapy, had a small tumor, and did not have lymph node metastases. The 30- and 90-day mortality rates in the video-assisted thoracic surgery and open thoracotomy groups were 1.8% vs. 2% and 2.6% vs. 2.5%, respectively. The five-year survival rates of video-assisted thoracic surgery and open thoracotomy groups were 74.1% and 65.2%, respectively (p>0.05). The 30- and 90-day mortality and five-year survival rates were 2.1%, 2.6%, and 73.5% in the video-assisted thoracic surgery group and 2.1%, 2.1%, and 68.5% in the open thoracotomy group, respectively, indicating no statistically significant difference between the two groups.
    Conclusion: Throughout the study period, video-assisted thoracic surgery was more preferred in patients with advanced age, in those who had a small tumor, who did not receive neoadjuvant therapy, did not have lymph node metastasis, and did not require any procedure other than lobectomy. In the video-assisted thoracic surgery and open thoracotomy groups, 30- and 90-day mortality and five-year survival rates were similar. Based on these findings, both procedures seem to be acceptable in this patient population.
    Language English
    Publishing date 2022-01-28
    Publishing country Turkey
    Document type Journal Article
    ISSN 1301-5680
    ISSN 1301-5680
    DOI 10.5606/tgkdc.dergisi.2022.20912
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Iterative surgical resections in non-small cell lung cancer

    Ahmet Ucvet / Serkan Yazgan / Ozgur Samancilar / Soner Gursoy / Ahmet Emin Erbaycu / Berna Komurcuoglu

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 18, Iss 4, Pp 221-

    2022  Volume 226

    Keywords lung cancer ; metachronous ; synchronous ; recurrence ; surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Iterative surgical resections in non-small cell lung cancer.

    Ucvet, Ahmet / Yazgan, Serkan / Samancilar, Ozgur / Gursoy, Soner / Erbaycu, Ahmet Emin / Komurcuoglu, Berna

    Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

    2022  Volume 18, Issue 4, Page(s) 221–226

    Abstract: Introduction: We reviewed our surgical preferences and the prognosis for recurrent and second primary tumors in patients who underwent surgical treatment for non-small cell lung carcinoma (NSCLC).: Aim: We report our experience with patients ... ...

    Abstract Introduction: We reviewed our surgical preferences and the prognosis for recurrent and second primary tumors in patients who underwent surgical treatment for non-small cell lung carcinoma (NSCLC).
    Aim: We report our experience with patients undergoing iterative pulmonary resection for lung cancer.
    Material and methods: Among patients who underwent anatomical resection for primary NSCLC, those who underwent a second surgical resection between 2010 and 2020 due to recurrent or second primary tumor were included in the study. Operative mortality, survival, and prognostic factors were investigated.
    Results: In total, 77 cases were included: 31 (40.3%) underwent the second resection for the recurrent disease and 46 (59.7%) underwent the second resection for the second primary tumor. Postoperative mortality occurred in 8 (10.4%) patients. All patients with postoperative mortality were in the group that underwent thoracotomy in both surgical procedures. The 5-year survival rate was 46.5%. The 5-year survival of those operated on for recurrent or second primary tumor was 32.8% and 51.1%, respectively (
    Conclusions: Our study shows that survival results similar to or better than primary NSCLC surgery can be obtained with lower mortality if more limited resections are performed via video-assisted thoracic surgery, especially in young patients. In addition, the prognosis is better in patients with an interval of more than 36 months between two operations.
    Language English
    Publishing date 2022-01-09
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2237053-5
    ISSN 1897-4252 ; 1731-5530
    ISSN (online) 1897-4252
    ISSN 1731-5530
    DOI 10.5114/kitp.2021.112188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Rethoracotomy for early complications: A marker for increased morbidity and mortality.

    Yazgan, Serkan / Üçvet, Ahmet / Gürsoy, Soner / Samancılar, Özgür

    Turk gogus kalp damar cerrahisi dergisi

    2018  Volume 26, Issue 3, Page(s) 441–449

    Abstract: Background: This study aims to examine the indications, timing and risk factors of rethoracotomy, analyze the postoperative results, and give suggestions to reduce the risks.: Methods: A total of 3,292 patients operated via thoracotomy between ... ...

    Abstract Background: This study aims to examine the indications, timing and risk factors of rethoracotomy, analyze the postoperative results, and give suggestions to reduce the risks.
    Methods: A total of 3,292 patients operated via thoracotomy between January 2006 and January 2017 were evaluated retrospectively. Demographic data, initial operative indications, surgical procedures, indications for rethoracotomy and preoperative risk factors, intraoperative findings and surgical methods, timing of rethoracotomy, morbidity and mortality results were analyzed of 66 patients (60 males, 6 females; mean age 59.4±12.4 years; range, 17 to 80 years) who were performed rethoracotomy before being discharged. Rethoracotomies performed within 72 hours after the first operation constituted the early and those performed after 72 hours constituted the late rethoracotomy group.
    Results: Rethoracotomy was performed in average 4.7 days (range, 1 to 17 days). Early rethoracotomy was performed on 42 patients (1.3%) and 38 (90.4%) of these were due to hemorrhage. The most frequent indication for rethoracotomy was hemorrhage (n=41, 1.2%), followed by bronchopleural fistula (n=17, 0.5%). The other indications were chylothorax, lobe torsion, parenchymal air leak and collapse, and diaphragmatic laceration. Eight patients had rib fractures and all of these patients were over the age of 60. Eight patients who were performed rethoracotomy due to hemorrhage were using antiaggregant drugs. The postoperative morbidity and mortality rates were 33.3% (n=22) and 24.2% (n=16), respectively.
    Conclusion: Rethoracotomy still has high morbidity and mortality rates. The main cause of rethoracotomy performed due to hemorrhage may be rib fractures or antiaggregant drugs. The most remarkable indications of rethoracotomy are hemorrhage and bronchopleural fistula.
    Language English
    Publishing date 2018-07-03
    Publishing country Turkey
    Document type Journal Article
    ISSN 1301-5680
    ISSN 1301-5680
    DOI 10.5606/tgkdc.dergisi.2018.15128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Completion pneumonectomy: Indications and outcomes in non-small cell lung cancer.

    Yazgan, Serkan / Üçvet, Ahmet / Gürsoy, Soner / Samancılar, Özgür

    Turk gogus kalp damar cerrahisi dergisi

    2018  Volume 26, Issue 4, Page(s) 626–635

    Abstract: Background: This retrospective single-center study aims to review the indications and outcomes of completion pneumonectomy after primary resection due to non-small cell lung cancer.: Methods: Of a total of 452 patients who underwent pneumonectomy ... ...

    Abstract Background: This retrospective single-center study aims to review the indications and outcomes of completion pneumonectomy after primary resection due to non-small cell lung cancer.
    Methods: Of a total of 452 patients who underwent pneumonectomy between January 2004 and August 2017 for non-small cell lung cancer, 29 (24 males, 5 females; mean age 59.9±7.1 years; range, 45 to 72 years) were performed completion pneumonectomy. Patients" indications, factors affecting early and late-term outcomes, operative mortality and survival rates were analyzed.
    Results: Operative mortality rate was 24.1%, including two intraoperative and five postoperative deaths. Complication rate was 44.8% and the most frequent complication was bronchopleural fistula with 24.1%. Study population was divided into two groups. While elective completion pneumonectomy group (n=19) consisted of recurrent malignant tumor patients, rescue completion pneumonectomy group (n=10) consisted of patients performed urgent pneumonectomy due to a bronchopulmonary complication developing after an anatomic lung resection. The morbidity and mortality rates for elective completion pneumonectomy and rescue completion pneumonectomy were 26.3% and 21.1%; and 70% and 30%, respectively. The morbidity for rescue completion pneumonectomy was significantly higher than elective completion pneumonectomy (p=0.016). Advanced age and presence of any preoperative risk (comorbidity and neoadjuvant treatment) were related to higher operative mortality (p=0.019 and p=0.049, respectively). The median survival after completion pneumonectomy was 19.5 months (95% confidence interval 17.2 to 21.9 months).
    Conclusion: The morbidity and mortality rates of completion pneumonectomy are higher than standard pneumonectomy. Rescue completion pneumonectomy is related to higher postoperative risk, but has better survival. The most significant complication after completion pneumonectomy is bronchopleural fistula. Advanced age and presence of any preoperative risk are related to statistically significantly higher mortality in completion pneumonectomy. Nevertheless, completion pneumonectomy is still a significant treatment option in selected patients.
    Language English
    Publishing date 2018-09-16
    Publishing country Turkey
    Document type Journal Article
    ISSN 1301-5680
    ISSN 1301-5680
    DOI 10.5606/tgkdc.dergisi.2018.16159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Türkiye'de Çin Algısı, 1923-1971

    Deniz Gürsoy

    Cappadocia Journal of Area Studies, Vol 3, Iss

    2021  Volume 1

    Abstract: ... teşkil eden niteliği bağlamında gelişen ilişkiler önem arz etmektedir. Son olarak ise Çin Halk ...

    Abstract Bu çalışma, Türkiye Cumhuriyeti’nin kurulduğu 1923 ile Türkiye’nin Çin Halk Cumhuriyeti’ni tanıdığı 1971 yılları arasında Türkiye Cumhuriyeti Cumhurbaşkanlığı Devlet Arşivleri Başkanlığı Cumhuriyet Arşivi’nde yer alan belgeler çerçevesinde, Türkiye resmi otoriteleri nezdindeki Çin algısını tartışmayı amaçlamaktadır. Bu dönem, söz konusu algının tarihsel birikimle nasıl biçimlendiği, Osmanlı döneminden devralınan bilgi ve siyaset birikiminin bu algıya nasıl yansıdığı ve özellikle iki ülkede gerçekleşen toplumsal, siyasal ve iktisadi dönüşümlerin bu algı bağlamında nasıl bir rol oynadığının incelenmesi için verimli bir dönemdir. Öncelikle Osmanlı’nın geç 19. yüzyıldaki Çin algısı değerlendirilecek ve bu dönemden Cumhuriyete intikal eden sürekliliklerin izi sürülecektir. Ardından Çin Halk Cumhuriyeti’nin kurulduğu 1949 yılına kadar olan dönemde, Türkiye ile Çin arasındaki diplomatik ilişkiler çerçevesinde iki ülkenin birbirini nasıl algıladığı ele alınacaktır. Bu dönemde Çin entelijansiyası için Kemalist modernleşmenin örnek teşkil eden niteliği bağlamında gelişen ilişkiler önem arz etmektedir. Son olarak ise Çin Halk Cumhuriyeti’nin kuruluşundan, Türkiye tarafından tanınmasına kadar geçen süreçte Türkiye resmi otoritelerinin Çin bölgesini ve bu bölgedeki hükümetleri nasıl gördüğüne bakılacaktır. Bu vesileyle, Türk devletinin Çin algısında süreklilik arz eden bazı nitelikler ile Çin Müslümanları, Doğu Türkistan ve Çin’in Rusya ile ilişkiler bakımından taşıdığı önem gibi konular olduğu; bununla birlikte Türkiye’nin ilgili dönemde bütünlüklü ve tek bir Çin politikasına sahip olmadığı bulguları ortaya konacaktır. Ayrıca, Türk dış politikasının, ilgili dönemde tek modeli ve kaynağı Avrupa olan belirli bir modernleşmeci bakış çerçevesinde işlemesi ve bu işleyişin Çin algısına yansımaları değerlendirilecektir.
    Keywords Çin ; Çin algısı ; modernleşme ; Türk dış politikası ; Cumhuriyet Arşivi ; History (General) ; D1-2009 ; Political science ; J
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Cappadocia University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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