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  1. Article: Less disease severity of COVID-19 among smokers: An indication of investigating nicotine as preventive measure.

    Ghayyur, Aysha / Hussain, Syed Shahzad / Salam, Emaan / Saeed, Subhan / Shahid, Saman / Salaam, Tanvir Us

    Pakistan journal of pharmaceutical sciences

    2021  Volume 34, Issue 1(Supplementary), Page(s) 321–325

    Abstract: The study was aimed to mention the epidemiology of smoking in Pakistani COVID-19 infected patients along with the disease severity, oxygen dependency and fatality rate. A cross sectional epidemiological study was carried out on 555 confirmed cases of ... ...

    Abstract The study was aimed to mention the epidemiology of smoking in Pakistani COVID-19 infected patients along with the disease severity, oxygen dependency and fatality rate. A cross sectional epidemiological study was carried out on 555 confirmed cases of COVID-19 infection. The median age was 47±16 years. 59% were male and 41% were female. Most of the patients (97.5%) survived, while only 2.5% expired. 25.6% patients required the oxygen. Total 17 (3%) COVID-19 patients with age 20-75 years were identified as smokers. No mortality was observed in smokers. The 1.4% smokers presented with mild disease, 1.2% with moderate disease and 0.4% had severe disease. According to Chi-Square test, there existed an insignificant difference (p-value: 0.38649) between smokers and non-smokers in disease severity levels. Smoking is a precursor for countless diseases, but it behaved differently in COVID-19 infected patients, as its prevalence was significantly low. We found no significant variation of the disease severity among the smokers and non-smokers. Profound experiments should be conducted to recommend whether nicotine can be used as a protective agent to negate COVID-19 infection.
    MeSH term(s) Adolescent ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; COVID-19/etiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Pakistan/epidemiology ; Severity of Illness Index ; Sex Distribution ; Smoking/epidemiology ; Tobacco Smoking/epidemiology ; Young Adult
    Language English
    Publishing date 2021-07-15
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6588: Show issues Location:
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  2. Article: Post-vaccination (COVID-19) impacts in healthcare personnel.

    Shahid, Saman / Ghayyur, Aysha / Majeed, Asma / Nisar, Subhana / Chaudary, Muhammad Anwar

    Pakistan journal of pharmaceutical sciences

    2021  Volume 34, Issue 5(Supplementary), Page(s) 1957–1962

    Abstract: The COVID-19 pandemic has brought attention back to its spread in medical staff. A survey-based study was conducted to combine general information related to COVID-19 exposures, acceptances, vaccines received, and side effects. The majority (62.3%) of ... ...

    Abstract The COVID-19 pandemic has brought attention back to its spread in medical staff. A survey-based study was conducted to combine general information related to COVID-19 exposures, acceptances, vaccines received, and side effects. The majority (62.3%) of healthcare professionals had acquired COVID-19 infection from hospital environment (51.5%) mainly who treated (64%) COVID-19 patients. 54% healthcare respondents expressed 'high acceptance' towards COVID-19 vaccines. 88% received COVID-19 vaccination. The majority of healthcare personnel received SinoPharm (65%). 82.3% did not acquire COVID-19 post-vaccination. 38% mild side effects were observed from vaccination. Following were the general side-effects: myalgia (18.2%), the feeling of sickness (16%), fever (15.6%), dizziness (7.8%), joint pain (7.4%), chills (4.8%), and flu (4.8%). Following were the common neurological side-effects reported: headache (18.2%), fatigue (16.5%), muscle pain (16%), numbness/tingling (3%), and migraine (2.6%). Nausea and diarrhoea were reported in only 3.5% of respondents. Bad taste was reported in only 3% of respondents. The 1.7% reported rash and itching. The majority of the healthcare professionals did not report significant side effects related to neurological, gastroenterological, skin and oral categories. To assess the vaccines' potential for substantial and long-term or chronic effects, more study with a larger sample size and a longer follow-up time is required.
    MeSH term(s) Adult ; COVID-19/immunology ; COVID-19/prevention & control ; COVID-19/transmission ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/adverse effects ; Drug-Related Side Effects and Adverse Reactions/etiology ; Female ; Health Care Surveys ; Health Personnel ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Male ; Occupational Exposure/adverse effects ; Occupational Exposure/prevention & control ; Occupational Health ; Pakistan ; Time Factors ; Treatment Outcome ; Vaccination/adverse effects ; Vaccination Hesitancy
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-11-10
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6588: Show issues Location:
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  3. Article: Depression and dementia from hyponatremia in brain cancer patients exposed to frozen food chemicals.

    Khalid, Sana / Shahid, Saman / Rasheed, Sajid / Iftikhar, Sadaf / Hussain, Syed Shahzad / Ghayyur, Aysha / Chaudhry, Muhammad Nawaz

    Pakistan journal of pharmaceutical sciences

    2020  Volume 32, Issue 6(Supplementary), Page(s) 2859–2864

    Abstract: Frozen food chemicals contain neurotoxins which disturb electrolyte levels. Altered electrolyte levels can induce mental illnesses. This study was focused on finding the prevalence of depression, dementia, intake of antidepressants and electrolytic ... ...

    Abstract Frozen food chemicals contain neurotoxins which disturb electrolyte levels. Altered electrolyte levels can induce mental illnesses. This study was focused on finding the prevalence of depression, dementia, intake of antidepressants and electrolytic alterations in brain cancer (BC) patients and in control group (CG) who were taking frozen and canned food. The levels of electrolytes were compared in both groups through Mann-Whitney U test. The Odds Ratio (OR) and Relative Risks (RR) were calculated of having a specific occurrence or condition of brain cancer patients vs. controls. Majority (41.42%) patients were from the age group 33-57 years. There were 52% male and 47% female patients. There was more occurrence of dementia (41%) and depression (6%) in patients as compared to CG. 94% patients were found with dementia. 32% patients were having low levels of sodium and 43% were having low levels of potassium. High levels of potassium (26%) were found in CG. 76% patients and 73% controls were taking canned food in moderation. 69% patients and 50% controls were taking frozen food in moderation. The potassium levels (p value: 0.00001) and sodium levels (p value: 0.01468) were found at significant difference in brain cancer patients and control group. Statistically significantly higher odds of outcome (OR>1) and increased relative risks (RR) were reported in dementia, depression and intake of anti-depressants for BC vs. CG. This epidemiological study reports hyponatremia as a significantly different parameter between brain cancer patients and controls. Food's chemicals induce hyponatremia, which can disturb mental states to develop different neurological conditions.
    MeSH term(s) Adolescent ; Adult ; Aged ; Antidepressive Agents/therapeutic use ; Brain Neoplasms/metabolism ; Brain Neoplasms/physiopathology ; Case-Control Studies ; Child ; Dementia/etiology ; Dementia/metabolism ; Depression/drug therapy ; Depression/etiology ; Depression/metabolism ; Female ; Frozen Foods/adverse effects ; Humans ; Hyponatremia/chemically induced ; Hyponatremia/metabolism ; Male ; Middle Aged ; Odds Ratio ; Potassium/metabolism ; Prevalence ; Risk ; Sodium/metabolism ; Young Adult
    Chemical Substances Antidepressive Agents ; Sodium (9NEZ333N27) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2020-01-28
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6588: Show issues Location:
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  4. Article: Impacts of intake of bakery food chemicals, degraded water and psychiatric drugs on liver & renal functions of brain tumor patients.

    Khalid, Sana / Shahid, Saman / Chaudhry, Muhammad Nawaz / Hussain, Syed Shahzad / Ghayyur, Aysha / Iftikhar, Sadaf / Rasheed, Sajid

    Pakistan journal of pharmaceutical sciences

    2019  Volume 32, Issue 4(Supplementary), Page(s) 1767–1772

    Abstract: A chemically preserved food has raised mental health issues. Abnormalities in liver and kidney functions have been reported from mentally imbalanced individuals. This study was focused on finding anxiety issues and biochemistry alterations in brain tumor ...

    Abstract A chemically preserved food has raised mental health issues. Abnormalities in liver and kidney functions have been reported from mentally imbalanced individuals. This study was focused on finding anxiety issues and biochemistry alterations in brain tumor patients and in controls. The levels of liver & kidney enzymes were compared in both groups through Mann-Whitney U test. Kendall's tau-b correlation was conducted to determine that is there any relationship between anxiety levels and biochemistry parameters in both groups. There was more occurrence of severe anxiety levels (58%) in brain tumor patients. There were more mood swings in CG (64%) as compared to BP (48%). Less sleeping pattern was found in CG (42%) as compared to BP (37%). More patients (58%) were having severe anxiety levels as compared to CG (52%). 73% patients were having low levels of alkaline phosphatase (AP). 52% individuals in CG were having low levels of AP. AP was found significantly associated with anxiety levels in brain tumor patients only. A nutrient deprived food from preservation can reduce levels of alkaline phosphatase. This can impact metabolism of necessary minerals for proper brain function. This epidemiological study reports a significant association between anxiety and reduced AP levels.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Alkaline Phosphatase/metabolism ; Antipsychotic Agents/adverse effects ; Anxiety/chemically induced ; Brain Neoplasms/metabolism ; Brain Neoplasms/physiopathology ; Case-Control Studies ; Child ; Epidemiologic Studies ; Female ; Food Additives/adverse effects ; Humans ; Kidney/drug effects ; Liver/drug effects ; Male ; Middle Aged ; Water/adverse effects ; Young Adult
    Chemical Substances Antipsychotic Agents ; Food Additives ; Water (059QF0KO0R) ; Alkaline Phosphatase (EC 3.1.3.1)
    Language English
    Publishing date 2019-10-26
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6588: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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