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  1. Book: Epigenetics and cancer

    Sarkar, Fazlul H.

    2013  

    Author's details Fazlul H. Sarkar ed
    Language English
    Size X, 287 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT017681507
    ISBN 978-94-007-6611-2 ; 94-007-6611-4 ; 9789400766129 ; 9400766122
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 1447 available for loan (reading room) Lesesaal EG

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  2. Book: MicroRNA targeted cancer therapy

    Sarkar, Fazlul H.

    2014  

    Author's details Fazlul H. Sarkar ed
    Keywords Cancer/Gene therapy ; Non-coding RNA/Therapeutic use
    Subject code 616.9940695
    Language English
    Size X, 351 S., illustrations (black and white, and colour), 24 cm
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018285187
    ISBN 978-3-319-05133-8 ; 9783319051345 ; 3-319-05133-4 ; 3319051342
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 2224 available for loan (reading room) Lesesaal EG

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book: Nutraceuticals and cancer

    Sarkar, Fazlul H.

    2012  

    Author's details Fazlul H. Sarkar ed
    Language English
    Size XII, 379 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT017079240
    ISBN 978-94-007-2629-1 ; 978-94-0072629-1 ; 94-0072629-5 ; 94-007-2629-5 ; 9789400726307 ; 9400726309
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 18 order for loan Magazin

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Novel Holistic Approaches for Overcoming Therapy Resistance in Pancreatic and Colon Cancers.

    Sarkar, Fazlul H

    Medical principles and practice : international journal of the Kuwait University, Health Science Centre

    2016  Volume 25 Suppl 2, Page(s) 3–10

    Abstract: Gastrointestinal (GI) cancers, such as of the colon and pancreas, are highly resistant to both standard and targeted therapeutics. Therapy-resistant and heterogeneous GI cancers harbor highly complex signaling networks (the resistome) that resist ... ...

    Abstract Gastrointestinal (GI) cancers, such as of the colon and pancreas, are highly resistant to both standard and targeted therapeutics. Therapy-resistant and heterogeneous GI cancers harbor highly complex signaling networks (the resistome) that resist apoptotic programming. Commonly used gemcitabine or platinum-based regimens fail to induce meaningful (i.e. disease-reversing) perturbations in the resistome, resulting in high rates of treatment failure. The GI cancer resistance networks are, in part, due to interactions between parallel signaling and aberrantly expressed microRNAs (miRNAs) that collectively promote the development and survival of drug-resistant cancer stem cells with epithelial-to-mesenchymal transition (EMT) characteristics. The lack of understanding of the resistance networks associated with this subpopulation of cells as well as reductionist, single protein-/pathway-targeted approaches have made 'effective drug design' a difficult task. We propose that the successful design of novel therapeutic regimens to target drug-resistant GI tumors is only possible if network-based drug avenues and agents, in particular 'natural agents' with no known toxicity, are correctly identified. Natural agents (dietary agents or their synthetic derivatives) can individually alter miRNA profiles, suppress EMT pathways and eliminate cancer stem-like cells that derive from pancreatic cancer and colon cancer, by partially targeting multiple yet meaningful networks within the GI cancer resistome. However, the efficacy of these agents as combinations (e.g. consumed in the diet) against this resistome has never been studied. This short review article provides an overview of the different challenges involved in the understanding of the GI resistome, and how novel computational biology can help in the design of effective therapies to overcome resistance.
    MeSH term(s) Antineoplastic Agents/therapeutic use ; Biological Products/therapeutic use ; Colonic Neoplasms/drug therapy ; Dietary Supplements ; Drug Discovery/methods ; Drug Discovery/trends ; Drug Resistance, Neoplasm ; Gastrointestinal Neoplasms/drug therapy ; Humans ; MicroRNAs ; Pancreatic Neoplasms/drug therapy
    Chemical Substances Antineoplastic Agents ; Biological Products ; MicroRNAs
    Language English
    Publishing date 2016
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 645108-1
    ISSN 1423-0151 ; 1011-7571
    ISSN (online) 1423-0151
    ISSN 1011-7571
    DOI 10.1159/000435814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2486: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Book: MicroRNA targeted cancer therapy

    Sarkar, Fazlul H

    2014  

    Author's details Fazlul H. Sarkar, editor
    MeSH term(s) MicroRNAs/therapeutic use ; Neoplasms/therapy ; Genetic Therapy/methods
    Language English
    Size x, 351 pages :, illustrations
    Document type Book
    ISBN 9783319051338 ; 3319051334 ; 9783319051345 ; 3319051342
    Database Catalogue of the US National Library of Medicine (NLM)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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  6. Article ; Online: Correction to: The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications.

    Sundararajan, Vignesh / Sarkar, Fazlul H / Ramasamy, Thamil Selvee

    Cellular oncology (Dordrecht)

    2018  Volume 41, Issue 4, Page(s) 463

    Abstract: In the title of above mentioned article the word 'versatile' had been replaced by 'multifaceted'. ...

    Abstract In the title of above mentioned article the word 'versatile' had been replaced by 'multifaceted'.
    Language English
    Publishing date 2018-07-25
    Publishing country Netherlands
    Document type Journal Article ; Published Erratum
    ZDB-ID 2595109-9
    ISSN 2211-3436 ; 1875-8606 ; 2211-3428
    ISSN (online) 2211-3436
    ISSN 1875-8606 ; 2211-3428
    DOI 10.1007/s13402-018-0396-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6908: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book: Epigenetics and cancer

    Sarkar, Fazlul H

    2013  

    Author's details Fazlul H. Sarkar, editor
    MeSH term(s) Neoplasms/genetics ; Epigenesis, Genetic ; MicroRNAs
    Language English
    Size x, 287 pages :, illustrations
    Document type Book
    ISBN 9789400766112 ; 9789400766129 ; 9400766114 ; 9400766122
    Database Catalogue of the US National Library of Medicine (NLM)

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    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Nutraceuticals and cancer. Preface.

    Sarkar, Fazlul H

    Cancer metastasis reviews

    2010  Volume 29, Issue 3, Page(s) 381–382

    MeSH term(s) Animals ; Dietary Supplements ; Humans ; Neoplasms/diet therapy
    Language English
    Publishing date 2010-09
    Publishing country Netherlands
    Document type Introductory Journal Article
    ZDB-ID 604857-2
    ISSN 1573-7233 ; 0167-7659
    ISSN (online) 1573-7233
    ISSN 0167-7659
    DOI 10.1007/s10555-010-9243-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1812: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Current trends in the chemoprevention of cancer.

    Sarkar, Fazlul H

    Pharmaceutical research

    2010  Volume 27, Issue 6, Page(s) 945–949

    MeSH term(s) Anticarcinogenic Agents/therapeutic use ; Chemoprevention/trends ; Humans ; Neoplasms/drug therapy ; Neoplasms/prevention & control
    Chemical Substances Anticarcinogenic Agents
    Language English
    Publishing date 2010-04-17
    Publishing country United States
    Document type Editorial ; Interview ; Introductory Journal Article
    ZDB-ID 843063-9
    ISSN 1573-904X ; 0724-8741 ; 0739-0742
    ISSN (online) 1573-904X
    ISSN 0724-8741 ; 0739-0742
    DOI 10.1007/s11095-010-0146-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1937: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Book: Nutraceuticals and cancer

    Sarkar, Fazlul H

    2012  

    Author's details Fazlul H. Sarkar, editor
    MeSH term(s) Neoplasms/diet therapy ; Functional Food
    Language English
    Size xii, 379 p. :, ill.
    Publisher Springer
    Publishing place Dordrecht
    Document type Book
    ISBN 9789400726291 ; 9400726295 ; 9789400726307 ; 9400726309
    Database Catalogue of the US National Library of Medicine (NLM)

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    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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