LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 37

Search options

  1. Article: Effects of Age at First Joining and Ewe Genotype on the Performance of Two-Tooth Ewes and That of Their Progeny to Slaughter.

    Keady, Timothy W J / Hanrahan, James P

    Animals : an open access journal from MDPI

    2022  Volume 12, Issue 5

    Abstract: ... Ewes were managed in a grass-based system. Ewes first joined at 7 months were lighter (p < 0.01) at 19 ... months and immediately post lambing; otherwise, age at first joining had no effects (p > 0.05) on ewes or ... their progeny and there were no important interactions with genotype. Bel and Suf × Bel had larger litters (p ...

    Abstract The effects of first-joining age (7 or 19 months) and genotype on ewe performance when joined to lamb at 2 years, and the performance of their progeny, were evaluated using 424 ewes, representing 3 genotypes: Belclare (Bel), Suffolk × Belclare (Suf × Bel) and Suffolk-type (≥75% Suffolk ancestry (Suf75)). Ewes were managed in a grass-based system. Ewes first joined at 7 months were lighter (p < 0.01) at 19 months and immediately post lambing; otherwise, age at first joining had no effects (p > 0.05) on ewes or their progeny and there were no important interactions with genotype. Bel and Suf × Bel had larger litters (p < 0.001) and reared more lambs per ewe joined (p < 0.01) than Suf75. Ewe genotype had no effect (p > 0.05) on proportion failing to lamb, incidence of lambing assistance, lamb mortality, ewe survival to 31 months, or progeny performance. Increasing the body weight of ewes at 7 months of age increased the probability (p < 0.02) of rearing 1 or more lambs at 2 years and there was no interaction with genotype. It is concluded that age at first joining had no negative impact on the performance of ewes or their progeny.
    Language English
    Publishing date 2022-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani12050653
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Effects of Age at First Joining and Ewe Genotype on the Performance of Two-Tooth Ewes and That of Their Progeny to Slaughter

    Timothy W. J. Keady / James P. Hanrahan

    Animals, Vol 12, Iss 653, p

    2022  Volume 653

    Abstract: ... Ewes were managed in a grass-based system. Ewes first joined at 7 months were lighter ( p < 0.01) at 19 ... months and immediately post lambing; otherwise, age at first joining had no effects ( p > 0.05) on ewes ... litters ( p < 0.001) and reared more lambs per ewe joined ( p < 0.01) than Suf75. Ewe genotype had no ...

    Abstract The effects of first-joining age (7 or 19 months) and genotype on ewe performance when joined to lamb at 2 years, and the performance of their progeny, were evaluated using 424 ewes, representing 3 genotypes: Belclare (Bel), Suffolk × Belclare (Suf × Bel) and Suffolk-type (≥75% Suffolk ancestry (Suf75)). Ewes were managed in a grass-based system. Ewes first joined at 7 months were lighter ( p < 0.01) at 19 months and immediately post lambing; otherwise, age at first joining had no effects ( p > 0.05) on ewes or their progeny and there were no important interactions with genotype. Bel and Suf × Bel had larger litters ( p < 0.001) and reared more lambs per ewe joined ( p < 0.01) than Suf75. Ewe genotype had no effect ( p > 0.05) on proportion failing to lamb, incidence of lambing assistance, lamb mortality, ewe survival to 31 months, or progeny performance. Increasing the body weight of ewes at 7 months of age increased the probability ( p < 0.02) of rearing 1 or more lambs at 2 years and there was no interaction with genotype. It is concluded that age at first joining had no negative impact on the performance of ewes or their progeny.
    Keywords grazing ; Suffolk ; Belclare ; litter size ; body condition score ; body size ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Review article: controversies surrounding the use of carvedilol and other beta blockers in the management of portal hypertension and cirrhosis.

    Gillespie, Sarah-Louise / Hanrahan, Timothy P / Rockey, Don C / Majumdar, Avik / Hayes, Peter C

    Alimentary pharmacology & therapeutics

    2023  Volume 57, Issue 5, Page(s) 454–463

    Abstract: Background: Advanced chronic liver disease is an increasing cause of premature morbidity and mortality in the UK. Portal hypertension is the primary driver of decompensation, including the development of ascites, hepatic encephalopathy and variceal ... ...

    Abstract Background: Advanced chronic liver disease is an increasing cause of premature morbidity and mortality in the UK. Portal hypertension is the primary driver of decompensation, including the development of ascites, hepatic encephalopathy and variceal haemorrhage. Non-selective beta blockers (NSBB) reduce portal pressure and are well established in the prevention of variceal haemorrhage. Carvedilol, a newer NSBB, is more effective at reducing portal pressure due to additional α-adrenergic blockade and has additional anti-oxidant, anti-inflammatory and anti-fibrotic effects.
    Aim: To summarise the available evidence on the use of beta blockers, specifically carvedilol, in cirrhosis, focussing on when and why to start METHODS: We performed a comprehensive literature search of PubMed for relevant publications.
    Results: International guidelines advise the use of NSBB in primary prophylaxis against variceal haemorrhage in those with high-risk varices, with substantial evidence of efficacy comparable with endoscopic band ligation (EBL). NSBB are also well established in secondary prophylaxis, in combination with EBL. More controversial is their use in patients without large varices, but with clinically significant portal hypertension. However, there is gathering evidence that NSBB, particularly carvedilol, reduce the risk of decompensation and improve survival. While caution is advised in patients with advanced cirrhosis and refractory ascites, recent evidence suggests that NSBB can continue to be used safely, and that premature discontinuation may be detrimental.
    Conclusions: With increasing evidence of benefit independent of variceal bleeding, namely retardation of decompensation and improvement in survival, it is time to consider whether carvedilol should be offered to all patients with advanced chronic liver disease.
    MeSH term(s) Humans ; Carvedilol/therapeutic use ; Esophageal and Gastric Varices/drug therapy ; Esophageal and Gastric Varices/prevention & control ; Esophageal and Gastric Varices/complications ; Ascites/etiology ; Ascites/complications ; Gastrointestinal Hemorrhage/drug therapy ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/prevention & control ; Adrenergic beta-Antagonists/therapeutic use ; Hypertension, Portal/complications ; Hypertension, Portal/drug therapy ; Liver Cirrhosis/complications ; Liver Cirrhosis/drug therapy ; Varicose Veins/complications
    Chemical Substances Carvedilol (0K47UL67F2) ; Adrenergic beta-Antagonists
    Language English
    Publishing date 2023-01-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.17380
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2206: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Effects of Age at First Joining and Ewe Genotype on the Performance of Two-Tooth Ewes and That of Their Progeny to Slaughter

    Keady, Timothy W. J. / Hanrahan, James P.

    Animals. 2022 Mar. 04, v. 12, no. 5

    2022  

    Abstract: ... Ewes were managed in a grass-based system. Ewes first joined at 7 months were lighter (p < 0.01) at 19 ... months and immediately post lambing; otherwise, age at first joining had no effects (p > 0.05) on ewes or ... their progeny and there were no important interactions with genotype. Bel and Suf × Bel had larger litters (p ...

    Abstract The effects of first-joining age (7 or 19 months) and genotype on ewe performance when joined to lamb at 2 years, and the performance of their progeny, were evaluated using 424 ewes, representing 3 genotypes: Belclare (Bel), Suffolk × Belclare (Suf × Bel) and Suffolk-type (≥75% Suffolk ancestry (Suf75)). Ewes were managed in a grass-based system. Ewes first joined at 7 months were lighter (p < 0.01) at 19 months and immediately post lambing; otherwise, age at first joining had no effects (p > 0.05) on ewes or their progeny and there were no important interactions with genotype. Bel and Suf × Bel had larger litters (p < 0.001) and reared more lambs per ewe joined (p < 0.01) than Suf75. Ewe genotype had no effect (p > 0.05) on proportion failing to lamb, incidence of lambing assistance, lamb mortality, ewe survival to 31 months, or progeny performance. Increasing the body weight of ewes at 7 months of age increased the probability (p < 0.02) of rearing 1 or more lambs at 2 years and there was no interaction with genotype. It is concluded that age at first joining had no negative impact on the performance of ewes or their progeny.
    Keywords ancestry ; body weight ; ewes ; genotype ; mortality ; probability ; progeny
    Language English
    Dates of publication 2022-0304
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani12050653
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Lessons From COVID-19, ACE2, and Intestinal Inflammation: Could a Virus Trigger Chronic Intestinal Inflammation?

    Hanrahan, Timothy P / Lubel, John S / Garg, Mayur

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2020  Volume 19, Issue 1, Page(s) 206

    MeSH term(s) COVID-19 ; Diarrhea ; Humans ; Inflammation ; Peptidyl-Dipeptidase A ; SARS-CoV-2
    Chemical Substances Peptidyl-Dipeptidase A (EC 3.4.15.1)
    Keywords covid19
    Language English
    Publishing date 2020-07-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2020.07.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5836: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: An Extraordinary Cause of Dyspnea and Weight Loss.

    Hanrahan, Timothy P / Goodwin, Mark / Testro, Adam

    Gastroenterology

    2020  Volume 160, Issue 3, Page(s) e19–e20

    MeSH term(s) Adult ; Angiography, Digital Subtraction ; Arteriovenous Fistula/diagnosis ; Arteriovenous Fistula/etiology ; Arteriovenous Fistula/therapy ; Cardiomegaly/diagnosis ; Cardiomegaly/etiology ; Dyspnea/etiology ; Embolization, Therapeutic ; Humans ; Intestines/transplantation ; Liver Transplantation/adverse effects ; Liver Transplantation/methods ; Male ; Mesenteric Arteries/abnormalities ; Mesenteric Arteries/diagnostic imaging ; Mesenteric Arteries/surgery ; Splenic Vein/abnormalities ; Splenic Vein/diagnostic imaging ; Splenic Vein/surgery ; Tomography, X-Ray Computed ; Treatment Outcome ; Weight Loss
    Language English
    Publishing date 2020-07-14
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2020.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.44: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 572: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Lessons From COVID-19, ACE2, and Intestinal Inflammation: Could a Virus Trigger Chronic Intestinal Inflammation?

    Hanrahan, Timothy P / Lubel, John S / Garg, Mayur

    Clin. gastroenterol. hepatol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #663872
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article: Reduced upper limb lean mass on dual energy X-ray absorptiometry predicts adverse outcomes in male liver transplant recipients.

    Hey, Penelope / Hoermann, Rudolf / Gow, Paul / Hanrahan, Timothy P / Testro, Adam G / Apostolov, Ross / Sinclair, Marie

    World journal of transplantation

    2022  Volume 12, Issue 6, Page(s) 120–130

    Abstract: Background: Pre-transplant muscle wasting measured by computed tomography has been associated with adverse clinical outcomes after liver transplantation including increased rates of sepsis and hospitalisation days. Upper limb lean mass (LM) measured by ... ...

    Abstract Background: Pre-transplant muscle wasting measured by computed tomography has been associated with adverse clinical outcomes after liver transplantation including increased rates of sepsis and hospitalisation days. Upper limb lean mass (LM) measured by dual-energy X-ray absorptiometry (DEXA) was recently identified as a novel predictor of sarcopenia-associated mortality in men waitlisted for transplantation.
    Aim: To investigate the use of DEXA LM in predicting gender-stratified early post-transplant outcomes.
    Methods: Liver transplant recipients who underwent pre-transplant DEXA body composition imaging between 2002 and 2017 were included. Endpoints included post-transplant mortality and graft failure, bacterial infections, acute cellular rejection (ACR) and intensive care and total hospital length of stay.
    Results: Four hundred and sixty-nine patients met inclusion criteria of which 338 were male (72%). Median age was 55.0 years (interquartile range 47.4, 59.7) and model for end-stage liver disease (MELD) score 16. Median time from assessment to transplantation was 7 mo (3.5, 12). Upper limb LM was inversely associated with bacterial infections at 180 d post-transplant (hazard ratio = 0.42; 95% confidence interval: 0.20-0.89;
    Conclusion: Sarcopenia is an independent and potentially modifiable predictor of increased post-transplant bacterial infections and hospital length of stay in men with cirrhosis. DEXA upper limb LM provides a novel measure of muscle wasting that has prognostic value in this cohort. The lack of association in women requires further investigation.
    Language English
    Publishing date 2022-08-01
    Publishing country United States
    Document type Journal Article
    ISSN 2220-3230
    ISSN 2220-3230
    DOI 10.5500/wjt.v12.i6.120
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Lessons From COVID-19, ACE2, and Intestinal Inflammation

    Hanrahan, Timothy P. / Lubel, John S. / Garg, Mayur

    Clinical Gastroenterology and Hepatology ; ISSN 1542-3565

    Could a Virus Trigger Chronic Intestinal Inflammation?

    2020  

    Keywords Hepatology ; Gastroenterology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.cgh.2020.07.036
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Antibiotic dosing in obesity: a BIG challenge.

    Hanrahan, Timothy P / Lipman, Jeffrey / Roberts, Jason A

    Critical care (London, England)

    2016  Volume 20, Issue 1, Page(s) 240

    Language English
    Publishing date 2016-08-10
    Publishing country England
    Document type Editorial
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/s13054-016-1426-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top